Comparison of the transmissibility of Trypanosoma congolense strains, isolated in a trypanosomiasis endemic area of eastern Zambia, by Glossina morsitans morsitans.

abstract：:Chagas infection is a major endemic disease affecting Latin American countries. The persistence of Trypanosoma cruzi generates a chronic inflammatory reactivity that induces an immune response directed to the host's tissues. The effectiveness of the treatment in the chronic phase is still unsatisfactory due, amongst o...

journal_title：Parasitology

authors： Fauro R,Lo Presti S,Bazan C,Baez A,Strauss M,Triquell F,Cremonezzi D,Negrete OS,Willhuber GC,Paglini-Oliva P,Rivarola HW

更新日期：2013-06-01 00:00:00

abstract：:A procedure is described for the isolation of sub-cellular fractions from bloodstream forms of Trypanosoma brucei. The method leaves intact most of the nuclei, mitochondria and microbodies. All the fractions have been chemically characterized and tested for 10 enzymatic markers. About 5% of total cell protein was isol...

journal_title：Parasitology

authors： Rovis L,Baekkeskov S

更新日期：1980-06-01 00:00:00

abstract：:Avian malaria is a vector transmitted disease caused by Plasmodium and recent studies suggest that variation in its prevalence across avian hosts is correlated with a variety of ecological traits. Here we examine the relationship between prevalence and diversity of Plasmodium lineages in southeastern Amazonia and: (1)...

journal_title：Parasitology

authors： Fecchio A,Ellis VA,Bell JA,Andretti CB,D'Horta FM,Silva AM,Tkach VV,Weckstein JD

更新日期：2017-07-01 00:00:00

abstract：:The twin concepts of zooprophylaxis and the dilution effect originated with vector-borne diseases (malaria), were driven forward by studies on Lyme borreliosis and have now developed into the mantra "biodiversity protects against disease". The basic idea is that by diluting the assemblage of transmission-competent hos...

journal_title：Parasitology

authors： Randolph SE,Dobson AD

更新日期：2012-06-01 00:00:00

abstract：:Treatment of BALB/c or MF1 mice with cyclosporin A (CsA) around the time of infection with Schistosoma mansoni conferred almost complete protection. The migration kinetics of L-[75Se]selenomethionine-labelled infective cercariae were investigated by compressed tissue autoradiography. Similar levels of skin penetration...

journal_title：Parasitology

authors： Munro GH,Brannan LR,Chappell LH,Thomson AW,McLaren DJ

更新日期：1991-02-01 00:00:00

abstract：:Ticks are of vast medical and veterinary public health importance due to direct damage caused by feeding and their roles in transmitting well known and emerging infectious agents. Ticks and tick-borne pathogens stimulate the immune system of the host. Those immune interactions are of importance in tick biology, pathog...

journal_title：Parasitology

authors： Brossard M,Wikel SK

更新日期：2004-01-01 00:00:00

abstract：:Avian malaria is a mosquito-borne disease caused by Plasmodium spp. protozoa. Although these parasites have been extensively studied in North America and Eurasia, knowledge on the diversity of Plasmodium, its vectors and avian hosts in Africa is scarce. In this study, we report on natural malarial infections in free-r...

journal_title：Parasitology

authors： Aly MZY,Mohamed III,Sebak SI,Vanstreels RET,El Gendy AM

更新日期：2020-08-01 00:00:00

abstract：:The development of resistance in mice to reinfection with Schistosoma mansoni was recorded during an early chronic infection, and compared with hepatic portal pathological and vascular changes. The latter were assessed using a microsphere injection technique. The degree of acquired resistance was directly dependent on...

journal_title：Parasitology

authors： McHugh SM,Coulson PS,Wilson RA

更新日期：1987-02-01 00:00:00

abstract：:A polymorphic set of 14 kDa excretory-secretory (E-S) antigen-encoding cDNAs, with similarity to a previously characterized 15 kDa E-S antigen of Haemonchus contortus, was cloned from Cooperia punctata. Five cDNAs encoding predicted proteins of 70-80% identity were sequenced. Genomic analyses of individuals proved the...

journal_title：Parasitology

authors： Yatsuda AP,De Vries E,Vieira Bressan MC,Eysker M

更新日期：2001-12-01 00:00:00

abstract：:Biozzi mice of Selections 1 and 3, each exhibiting either high- or low-antibody responses to a wide range of antigens, were exposed to primary, secondary and tertiary infections of the nematode, Nematospiroides dubius. The course of these infections was followed by monitoring egg output and by examination of the worm ...

journal_title：Parasitology

authors： Jenkins DC,Carrington TS

更新日期：1981-04-01 00:00:00

abstract：:Fractionation of Schistosoma mansoni cercariae gland secretion on a Sephadex G-150 column followed by a Superose-12 column in an FPLC system, isolated a 47 kDa protease which migrated as a single band on SDS-PAGE gels. A monoclonal antibody (MAb) was produced which recognizes only the 47 kDa protease, and an immuno-af...

journal_title：Parasitology

authors： Chavez-Olortegui C,Resende M,Tavares CA

更新日期：1992-10-01 00:00:00

abstract：:A cDNA encoding a beta-galactoside-binding lectin (galectin) was identified by immunoscreening a Haemonchus contortus cDNA library with antisera from lambs vaccinated with a membrane protein complex (H-gal-GP) derived from the parasites' gut. The cDNA sequence, exhibiting a tandem repeat structure and designated Hco-g...

journal_title：Parasitology

authors： Newlands GF,Skuce PJ,Knox DP,Smith SK,Smith WD

更新日期：1999-11-01 00:00:00

abstract：:The numbers, distribution in the small intestine, sexual development and growth (dry weight) of 5-week-old Moniliformis dubius (Acanthocephala) were investigated experimentally in adult, female CFHB rats fed on theoretically isoenergetic diets containing known amounts of fructose in combination with either maize-oil f...

journal_title：Parasitology

authors： Crompton DW,Keymer A,Singhvi A,Nesheim MC

更新日期：1983-02-01 00:00:00

abstract：:This paper reviews naturally occurring and synthetic compounds that either enhance immune defences or lower both natural and acquired immunity. Immunomodulatory agents used both for laboratory study and clinically for the management of immunologically based diseases are considered. ...

journal_title：Parasitology

authors： Nüssler AK,Thomson AW

更新日期：1992-01-01 00:00:00

abstract：:Expression of metalloprotease activities during metacyclogenesis of a series of strains and clones of Trypanosoma cruzi was investigated using SDS-polyacrylamide gel electrophoresis with a range of different co-polymerized proteolytic substrates. A complex pattern of metalloprotease expression, with considerable quant...

journal_title：Parasitology

authors： Lowndes CM,Bonaldo MC,Thomaz N,Goldenberg S

更新日期：1996-04-01 00:00:00

abstract：:African sleeping sickness is a parasitic disease transmitted through the bites of tsetse flies of the genus Glossina. We constructed mechanistic models for the basic reproduction number, R0, of Trypanosoma brucei gambiense and Trypanosoma brucei rhodesiense, respectively the causative agents of West and East African h...

journal_title：Parasitology

authors： Davis S,Aksoy S,Galvani A

更新日期：2011-04-01 00:00:00

abstract：:This review of protozoan and helminth infections in pregnancy focuses on the impact on the immune response in the newborn infant to maternal infection. Studies of protozoan and helminth infections in pregnant women and in their offspring have shown that children exposed to antigens or microorganisms during pregnancy o...

journal_title：Parasitology

authors： Petersen E

更新日期：2007-01-01 00:00:00

abstract：:This review focuses on some of the more ground-shifting advances of recent decades, particularly those at the molecular and cellular level that illuminate mechanisms underpinning the natural ecology of tick-host-pathogen interactions and the consequent epidemiology of zoonotic infections in humans. Knowledge of compon...

journal_title：Parasitology

authors： Randolph SE

更新日期：2009-10-01 00:00:00

abstract：:Neurological involvement following trypanosome infection has been recognised for over a century. However, there are still many unanswered questions concerning the mechanisms used by the parasite to gain entry to the CNS and the pathogenesis of the resulting neuroinflammatory reaction. There is a paucity of material fr...

journal_title：Parasitology

authors： Rodgers J

更新日期：2010-12-01 00:00:00

abstract：:Prevention of heartworm disease caused by Dirofilaria immitis in domestic dogs and cats relies on a single drug class, the macrocyclic lactones (MLs). Recently, it has been demonstrated that ML-resistant D. immitis are circulating in the Mississippi Delta region of the USA, but the prevalence and impact of these resis...

journal_title：Parasitology

authors： Wolstenholme AJ,Evans CC,Jimenez PD,Moorhead AR

更新日期：2015-09-01 00:00:00

abstract：:A double antibody sandwich ELISA technique has been developed for detection of antigens of African trypanosomes present in the sera of infected mammals. The assay uses a high titre, high affinity rabbit antiserum made to purified membranes of procyclic trypanosomes as "capture" reagent and a mixture of three biotin-la...

journal_title：Parasitology

authors： Liu MK,Pearson TW

更新日期：1987-10-01 00:00:00

abstract：:Ligand-gated chloride channels (LGCCs) are key components of the nervous system of parasitic nematodes and important targets for anthelmintics. Here, we describe the isolation and characterization of a novel member of the LGCC gene family (HcLGCC1) from the parasitic nematode Haemonchus contortus. Sequence analysis re...

journal_title：Parasitology

authors： Forrester SG,Siddiqui SZ

更新日期：2008-04-01 00:00:00

abstract：:A time-course study was conducted to resolve discrepancies in the literature and better define aspects of the Eimeria maxima life cycle such, as sites of development and both morphology and number of asexual stages. Broiler chickens were inoculated orally with five million E. maxima oocysts (APU1), and were necropsied...

journal_title：Parasitology

authors： Dubey JP,Jenkins MC

更新日期：2018-07-01 00:00:00

abstract：:Ivermectin treatment may induce severe adverse reactions in some individuals heavily infected with Loa loa. This hampers the implementation of mass ivermectin treatment against onchocerciasis in areas where Onchocerca volvulus and L. loa are co-endemic. In order to identify factors, including co-infections, which may ...

journal_title：Parasitology

authors： Pion SD,Clarke P,Filipe JA,Kamgno J,Gardon J,Basáñez MG,Boussinesq M

更新日期：2006-06-01 00:00:00

abstract：:Species composition of wild reservoir hosts can influence the transmission and maintenance of multi-host vector borne pathogens. The 'pace of life' hypothesis proposes that the life history strategy of reservoir hosts can influence pathogen transmission of vector borne generalist pathogens. We use empirical data to pa...

journal_title：Parasitology

authors： Erazo D,Cordovez J,Cabrera C,Calzada JE,Saldaña A,Gottdenker NL

更新日期：2017-12-01 00:00:00

abstract：:The World Health Organization announced in November 2014 at the fourth international meeting on 'the control of neglected zoonotic diseases - from advocacy to action', that intervention tools for eliminating Taenia solium taeniosis/cysticercosis (TSTC) are in place. The aim of this work was to elucidate theoretical ou...

journal_title：Parasitology

authors： Johansen MV,Trevisan C,Gabriël S,Magnussen P,Braae UC

更新日期：2017-01-01 00:00:00

abstract：:Alveolar echinococcosis (AE) is a zoonotic parasitic diseases caused by a cestode parasite known as Echinococcus multilocularis. The parasite has a wildlife cycle with definitive hosts (foxes) and small mammals as intermediate hosts (rodents) while humans are the accidental hosts. Parasite infection pressure relation ...

journal_title：Parasitology

authors： Khan A,Ahmed H,Sohail A,Alam F,Simsek S

更新日期：2020-03-01 00:00:00

abstract：:Within the genus Cryptosporidium 2 lineages have evolved, one adapted to the acid environment of the stomach and abomasum, the other comprising parasites that multiply in the small intestine. We tested whether the release of sporozoites from oocysts, a process known as excystation, is triggered by conditions which mim...

journal_title：Parasitology

authors： Widmer G,Klein P,Bonilla R

更新日期：2007-10-01 00:00:00

abstract：:Antibodies against the retrovirus envelope glycoprotein (gp70) of mouse xenotropic retrovirus, BALB virus 2 (Bv2) reacted with the adult worms of Schistosoma japonicum and S. mansoni. This reaction was completely inhibited after adsorption of the antibodies with virions of retrovirus. The reactive schistosome antigen ...

journal_title：Parasitology

authors： Tanaka M,Iwamura Y,Amanuma H,Irie Y,Watanabe M,Watanabe T,Uchiyama Y,Yasuraoka K

更新日期：1989-08-01 00:00:00

abstract：:Stratospheric ozone depletion threatens to increase exposure to ultraviolet (UV) radiation which is known to be a factor in a number of diseases. There is little doubt that cumulative exposure to UV radiation is important in the aetiology of non-melanoma skin cancers. Evidence is also strong for a link with cutaneous ...

journal_title：Parasitology

authors： Bentham G

更新日期：1993-01-01 00:00:00