Immunomodulatory agents in the laboratory and clinic.

Abstract:

:This paper reviews naturally occurring and synthetic compounds that either enhance immune defences or lower both natural and acquired immunity. Immunomodulatory agents used both for laboratory study and clinically for the management of immunologically based diseases are considered.

journal_name

Parasitology

journal_title

Parasitology

authors

Nüssler AK,Thomson AW

doi

10.1017/s0031182000075326

subject

Has Abstract

pub_date

1992-01-01 00:00:00

pages

S5-23

eissn

0031-1820

issn

1469-8161

journal_volume

105 Suppl

pub_type

杂志文章,评审
  • Parasite biodiversity and its determinants in coastal marine teleost fishes of Brazil.

    abstract::Recent studies of the forces behind the diversification of parasite assemblages have shed light on many aspects of parasite biodiversity. By using only parasite species richness as their measure of diversity, however, previous investigations have ignored the relatedness among parasite species and the taxonomic structu...

    journal_title:Parasitology

    pub_type: 杂志文章

    doi:10.1017/s0031182004005050

    authors: Luque JL,Mouillot D,Poulin R

    更新日期:2004-06-01 00:00:00

  • Multi-scale spatial analysis of human alveolar echinococcosis risk in China.

    abstract::Risk factors for the transmission of Echinococcus multilocularis to humans operate at a range of spatial scales. Over a large area, such as China, regional scale risk is correlated with variation in climatic conditions because of its effect on the spatial distribution of landscapes that can support E. multilocularis t...

    journal_title:Parasitology

    pub_type: 杂志文章,评审

    doi:

    authors: Danson FM,Graham AJ,Pleydell DR,Campos-Ponce M,Giraudoux P,Craig PS

    更新日期:2003-01-01 00:00:00

  • Ribonucleic acid synthesis in Plasmodium knowlesi maintained both in vivo and in vitro.

    abstract::RNA extracted from purified parasites of Plasmodium knowlesi was fractionated using agarose gel electrophoresis. Preparations from para sites grown both in vivo and in vitro contained species of RNA with sedimentation coefficients of 4-0S, 5-0S, 16-6S, 24-2S, 31-4S, 38-0S and 48-3S. There was less RNA present in paras...

    journal_title:Parasitology

    pub_type: 杂志文章

    doi:10.1017/s0031182000046655

    authors: Trigg PI,Shakespeare PG,Burt SJ,Kyd SI

    更新日期:1975-10-01 00:00:00

  • Evolutionary pressures in the spread and persistence of infectious agents in vertebrate populations.

    abstract::Infectious agents have considerable potential to regulate or constrain the population growth of vertebrate hosts in natural habitats. A broad theoretical framework provides many insights into how the biology of the parasite and the demography of the host interact to determine this impact. It may manifest itself as a s...

    journal_title:Parasitology

    pub_type: 杂志文章,评审

    doi:10.1017/s003118200007579x

    authors: Anderson RM

    更新日期:1995-01-01 00:00:00

  • Nitric oxide interaction with IL-10, MIP-1alpha, MCP-1 and RANTES over the in vitro granuloma formation against different Schistosoma mansoni antigenic preparations on human schistosomiasis.

    abstract::Nitric oxide (NO) produced by cytokine-activated macrophages is reported to be cytotoxic against the helminth Schistosoma mansoni, although this is a controversial issue. Previous work in our laboratory identified a fraction of S. mansoni soluble adult worm antigenic preparation (SWAP), named PIII, able to elicit sign...

    journal_title:Parasitology

    pub_type: 杂志文章

    doi:10.1017/s0031182099005636

    authors: Oliveira DM,Silva-Teixeira DN,Gustavson S,Oliveira SM,Goes AM

    更新日期:2000-04-01 00:00:00

  • The effect of non-immune stresses on the development of Strongyloides ratti.

    abstract::Strongyloides ratti is a parasitic nematode of rats. The host immune response against S. ratti affects the development of its free-living generation, favouring the development of free-living adult males and females at the expense of directly developing, infective 3rd-stage larvae. However, how the host immune response...

    journal_title:Parasitology

    pub_type: 杂志文章

    doi:10.1017/s0031182005007675

    authors: Crook M,Viney ME

    更新日期:2005-09-01 00:00:00

  • The effect of infection with Lyme disease spirochetes (Borrelia burgdorferi) on the phototaxis, activity, and questing height of the tick vector Ixodes scapularis.

    abstract::Little is known about the effects of infection with Borrelia burgdorferi, the bacterium that causes Lyme disease, on its tick vectors. The purpose of this study was to determine the behavioural and ecological effects of infection by the bacterium in nymphal and adult black-legged (Ixodes scapularis) ticks. We found th...

    journal_title:Parasitology

    pub_type: 杂志文章

    doi:10.1017/s0031182000066336

    authors: Lefcort H,Durden LA

    更新日期:1996-08-01 00:00:00

  • Low-dose oral administration of human interferon alpha can control the development of Theileria parva infection in cattle.

    abstract::Two natural human interferon alpha preparations, (nHuIFN-alpha [Cantell]) and (nHuIFN-alpha [ISI]), were used for the oral treatment of cattle experimentally infected with Theileria parva parva. In the first experiment, 8 Friesian bulls were inoculated with a 1 in 10 dilution of a sporozoite stabilate of T.p. parva (M...

    journal_title:Parasitology

    pub_type: 杂志文章

    doi:10.1017/s0031182000063241

    authors: Young AS,Maritim AC,Kariuki DP,Stagg DA,Wafula JM,Mutugi JJ,Cummins JM,Richards AB,Burns C

    更新日期:1990-10-01 00:00:00

  • Species or local environment, what determines the infection of rodents by Toxoplasma gondii?

    abstract::Toxoplasmosis is largely present in rural areas but its spatial distribution in this environment remains poorly known. In particular, it is unclear if areas of high density of cats, the only hosts excreting Toxoplasma gondii, constitute foci of high prevalence. To improve our understanding of the spatial distribution ...

    journal_title:Parasitology

    pub_type: 杂志文章

    doi:10.1017/S0031182013001522

    authors: Gotteland C,Chaval Y,Villena I,Galan M,Geers R,Aubert D,Poulle ML,Charbonnel N,Gilot-Fromont E

    更新日期:2014-02-01 00:00:00

  • Schistosoma mansoni: evidence for a role of serum factors in protecting artificially transformed schistosomula against antibody-mediated killing in vitro.

    abstract::Artificially transformed schistosomula of Schistosoma mansoni develop a consistent but small protection against the lethal effects of antibody plus complement when cultured for 24 h in a chemically defined medium. In contrast, they become rapidly resistant to antibody plus complement, when cultured in the presence of ...

    journal_title:Parasitology

    pub_type: 杂志文章

    doi:10.1017/s0031182000049404

    authors: Tavares CA,Soares RC,Coelho PM,Gazzinelli G

    更新日期:1978-10-01 00:00:00

  • Signatures of mito-nuclear discordance in Schistosoma turkestanicum indicate a complex evolutionary history of emergence in Europe.

    abstract::High levels of molecular diversity were identified in mitochondrial cytochrome c oxidase (cox1) gene sequences of Schistosoma turkestanicum from Hungary. These cox1 sequences were all specific to Hungary which contrasted with the low levels of diversity seen in the nuclear internal transcribed spacer region (ITS) sequ...

    journal_title:Parasitology

    pub_type: 杂志文章

    doi:10.1017/S0031182017000920

    authors: Lawton SP,Bowen LI,Emery AM,Majoros G

    更新日期:2017-11-01 00:00:00

  • Detection of Neospora caninum in aborted bovine fetuses and dam blood samples by nested PCR and ELISA and seroprevalence in Beijing and Tianjin, China.

    abstract::Neospora caninum infection is a significant cause of abortion in cattle. We investigated the tissue distribution of N. caninum in aborted bovine fetuses and dam blood samples by a nested PCR assay, and compared the nested PCR with ELISA in the diagnosis of N. caninum infection. In total, 26 aborted fetuses and 813 blo...

    journal_title:Parasitology

    pub_type: 杂志文章

    doi:10.1017/S0031182009990813

    authors: Yao L,Yang N,Liu Q,Wang M,Zhang W,Qian WF,Hu YF,Ding J

    更新日期:2009-09-01 00:00:00

  • Alpha proteobacteria of genus Anaplasma (Rickettsiales: Anaplasmataceae): Epidemiology and characteristics of Anaplasma species related to veterinary and public health importance.

    abstract::The Anaplasma species are important globally distributed tick-transmitted bacteria of veterinary and public health importance. These pathogens, cause anaplasmosis in domestic and wild animal species including humans. Rhipicephalus, Ixodes, Dermacentor and Amblyomma genera of ticks are the important vectors of Anaplasm...

    journal_title:Parasitology

    pub_type: 杂志文章,评审

    doi:10.1017/S0031182016000238

    authors: Atif FA

    更新日期:2016-05-01 00:00:00

  • Consumer and host body size effects on the removal of trematode cercariae by ambient communities.

    abstract::Parasite transmission can be altered via the removal of parasites by the ambient communities in which parasite-host interactions take place. However, the mechanisms driving parasite removal remain poorly understood. Using marine trematode cercariae as a model system, we investigated the effects of consumer and host bo...

    journal_title:Parasitology

    pub_type: 杂志文章

    doi:10.1017/S0031182018001488

    authors: Welsh JE,Hempel A,Markovic M,van der Meer J,Thieltges DW

    更新日期:2019-03-01 00:00:00

  • Neutral lipids and the assessment of infectivity in entomopathogenic nematodes: observations on four Steinernema species.

    abstract::An 8-point visual index was developed for Oil Red O staining of neutral lipids in infective juveniles (IJs) of Steinernema carpocapsae (A11), S. riobravis (Biosys 355), S. feltiae (UK76) and S. glaseri (NC). The visual index was found to be a reliable and rapid method for determining the relative neutral lipid content...

    journal_title:Parasitology

    pub_type: 杂志文章

    doi:10.1017/s0031182096008748

    authors: Patel MN,Stolinski M,Wright DJ

    更新日期:1997-05-01 00:00:00

  • Hymenolepis diminuta-induced fecundity reduction may be caused by changes in hormone binding to Tenebrio molitor ovaries.

    abstract::Aspects of vitellogenesis, known to be controlled by juvenile hormone, are adversely affected by Hymenolepis diminuta infection of Tenebrio molitor, in spite of circulating titres of the hormone remaining unchanged. It has therefore been proposed that juvenile hormone binding is disrupted at the tissue site level. Juv...

    journal_title:Parasitology

    pub_type: 杂志文章

    doi:10.1017/s0031182000065288

    authors: Webb TJ,Hurd H

    更新日期:1995-06-01 00:00:00

  • Isolation and characterization of secretions from the plant-parasitic nematode Globodera pallida.

    abstract::Electrophoresis of secretions collected from Globodera pallida revealed a smeared region between 25 and 50 kDa, and a single band of < 20 kDa. The secretions were used to raise an antiserum (LW1). Immunoblotting of parasite homogenates with LW1 differentiated G. pallida from its sibling species G. rostochiensis and re...

    journal_title:Parasitology

    pub_type: 杂志文章

    doi:10.1017/s0031182097001443

    authors: Duncan LH,Robertson L,Robertson WM,Kusel JR

    更新日期:1997-10-01 00:00:00

  • Antiparasitic effects of ethanolic extracts of Piper arboreum and Jatropha gossypiifolia leaves on cercariae and adult worms of Schistosoma mansoni.

    abstract::New treatment strategies for schistosomiasis should be evaluated, since resistant strains to the only available drug, Praziquantel, have already been described. Thus, we demonstrated antiparasitic effects of ethanolic extracts of Jatropha gossypiifolia and Piper arboreum on cercariae and adult worms of Schistosoma man...

    journal_title:Parasitology

    pub_type: 杂志文章

    doi:10.1017/S003118202000181X

    authors: da Silva Alves RR,Mendes Rodrigues JG,Teles-Reis A,Araújo Nogueira R,Correia Lima Licá I,Sampaio Lira MG,da Silva Alves R,Silva-Souza N,Aguiar Dos Santos Andrade TJ,Silva Miranda G

    更新日期:2020-12-01 00:00:00

  • Properties and localization of chitin synthase in Ascaris suum eggs.

    abstract::Investigations were carried out into the properties and localization of chitin synthase (EC 2.4.1.16) in connection with the formation of Ascaris suum egg-shells. The chitin synthase of eggs exhibited properties very similar to those found in other chitin-synthesizing organisms. It was stimulated by the presence of AT...

    journal_title:Parasitology

    pub_type: 杂志文章

    doi:10.1017/s0031182000063575

    authors: Dubinský P,Rybos M,Turceková L

    更新日期:1986-02-01 00:00:00

  • Exposure of small mammals to ticks and rickettsiae in Atlantic Forest patches in the metropolitan area of Recife, North-eastern Brazil.

    abstract::Between December 2007 and March 2009, small mammals were captured in 6 Atlantic Forest patches in Brazil. We assessed tick-host associations and whether they differ among forest strata, sites, seasons, and host age classes or between sexes. Moreover, we assessed the exposure of animals to Rickettsia spp. In total, 432...

    journal_title:Parasitology

    pub_type: 杂志文章

    doi:10.1017/S0031182011001740

    authors: Dantas-Torres F,Aléssio FM,Siqueira DB,Mauffrey JF,Marvulo MF,Martins TF,Moraes-Filho J,Camargo MC,D'Auria SR,Labruna MB,Silva JC

    更新日期:2012-01-01 00:00:00

  • Parasitism and phenotypic change in colonial hosts.

    abstract::Changes in host phenotype are often attributed to manipulation that enables parasites to complete trophic transmission cycles. We characterized changes in host phenotype in a colonial host–endoparasite system that lacks trophic transmission (the freshwater bryozoan Fredericella sultana and myxozoan parasite Tetracapsu...

    journal_title:Parasitology

    pub_type: 杂志文章

    doi:10.1017/S0031182013000899

    authors: Hartikainen H,Fontes I,Okamura B

    更新日期:2013-09-01 00:00:00

  • Glomerular disease associated with Polysporoplasma sparis (Myxozoa) infections in cultured gilthead sea bream, Sparus aurata L. (Pisces: Teleostei).

    abstract::Polysporoplasma sparis infection was studied in gilthead sea bream from different mariculture systems of the Spanish coasts. Culture conditions influenced the infection dynamics, as the parasite appeared only in semi-intensive cultures and was not found in intensive closed systems nor in open ones. No clear seasonal p...

    journal_title:Parasitology

    pub_type: 杂志文章

    doi:10.1017/s0031182098003758

    authors: Palenzuela O,Alvarez-Pellitero P,Sitjà-Bobadilla A

    更新日期:1999-03-01 00:00:00

  • The effect of Giardia lamblia trophozoites on trypsin, chymotrypsin and amylase in vitro.

    abstract::Giardia lamblia localize and multiply in the small intestine and may cause acute or chronic diarrhoea with malabsorption of fat, protein and other nutrients. Abnormal pancreatic function has been documented in giardiasis and trophozoites directly inhibit pancreatic lipase activity in vitro. The aim of this study was t...

    journal_title:Parasitology

    pub_type: 杂志文章

    doi:10.1017/s0031182000075053

    authors: Seow F,Katelaris P,Ngu M

    更新日期:1993-04-01 00:00:00

  • Trypanosomiasis and the brain.

    abstract::Neurological involvement following trypanosome infection has been recognised for over a century. However, there are still many unanswered questions concerning the mechanisms used by the parasite to gain entry to the CNS and the pathogenesis of the resulting neuroinflammatory reaction. There is a paucity of material fr...

    journal_title:Parasitology

    pub_type: 杂志文章,评审

    doi:10.1017/S0031182009991806

    authors: Rodgers J

    更新日期:2010-12-01 00:00:00

  • Integrating the landscape epidemiology and genetics of RNA viruses: rabies in domestic dogs as a model.

    abstract::Landscape epidemiology and landscape genetics combine advances in molecular techniques, spatial analyses and epidemiological models to generate a more real-world understanding of infectious disease dynamics and provide powerful new tools for the study of RNA viruses. Using dog rabies as a model we have identified how ...

    journal_title:Parasitology

    pub_type: 杂志文章,评审

    doi:10.1017/S003118201200090X

    authors: Brunker K,Hampson K,Horton DL,Biek R

    更新日期:2012-12-01 00:00:00

  • Spatial and temporal structure of the trematode component community in Valvata macrostoma (Gastropoda, Prosobranchia).

    abstract::We conducted the first comprehensive study on the spatiotemporal structure of trematode communities in the large-mouthed valve snail, Valvata macrostoma. A total of 1103 snails were examined monthly between May and October 2007 from Lake Konnevesi, Central Finland, from a shallow (1-2 m deep) and an offshore site (5-6...

    journal_title:Parasitology

    pub_type: 杂志文章

    doi:10.1017/S0031182008005027

    authors: Faltýnková A,Valtonen ET,Karvonen A

    更新日期:2008-12-01 00:00:00

  • Haemoproteid parasites of Passer spp.

    abstract::The taxonomic status of the haemoproteid parasites hitherto described from the avian genus Passer is reviewed. It is concluded that 1 species only is valid Haemoproteus passeris Kruse (1890), all other species being designated as synonyms. From material obtained from Passer domesticus a re-description is given of H. p...

    journal_title:Parasitology

    pub_type: 杂志文章

    doi:10.1017/s0031182000047077

    authors: Peirce MA

    更新日期:1976-12-01 00:00:00

  • Protozoan and helminth infections in pregnancy. Short-term and long-term implications of transmission of infection from mother to foetus.

    abstract::This review of protozoan and helminth infections in pregnancy focuses on the impact on the immune response in the newborn infant to maternal infection. Studies of protozoan and helminth infections in pregnant women and in their offspring have shown that children exposed to antigens or microorganisms during pregnancy o...

    journal_title:Parasitology

    pub_type: 杂志文章,评审

    doi:10.1017/S0031182007000182

    authors: Petersen E

    更新日期:2007-01-01 00:00:00

  • Transcriptome analysis during the process of in vitro differentiation of Leishmania donovani using genomic microarrays.

    abstract::Leishmania donovani causes visceral disease (kala-azar), a major health problem throughout the tropics with 500 000 new cases every year. Leishmania differentiates from the promastigote to the amastigote form to establish infection in a mammalian host. To understand the process of differentiation, we assessed the glob...

    journal_title:Parasitology

    pub_type: 杂志文章

    doi:10.1017/S003118200700296X

    authors: Srividya G,Duncan R,Sharma P,Raju BV,Nakhasi HL,Salotra P

    更新日期:2007-10-01 00:00:00

  • Behaviour of Toxoplasma gondii RH Ankara strain tachyzoites during continuous production in various cell lines.

    abstract::Toxoplasma gondii is an obligate intracellular protozoan parasite. The objective of the present study was to examine the behaviour of Toxoplasma gondii RH Ankara strain tachyzoites in a cell culture environment. The study represents the first step in determining whether T. gondii RH Ankara strain tachyzoites, grown in...

    journal_title:Parasitology

    pub_type: 杂志文章

    doi:10.1017/S0031182005009078

    authors: Döskaya M,Degirmenci A,Ciçek C,Ak M,Korkmaz M,Gürüz Y,Uner A

    更新日期:2006-03-01 00:00:00