Depletion of the ozone layer: consequences for non-infectious human diseases.

Abstract:

:Stratospheric ozone depletion threatens to increase exposure to ultraviolet (UV) radiation which is known to be a factor in a number of diseases. There is little doubt that cumulative exposure to UV radiation is important in the aetiology of non-melanoma skin cancers. Evidence is also strong for a link with cutaneous malignant melanoma, although here it appears to be intermittent intense exposure that is most damaging. More controversial is the view that exposure to solar radiation is a significant factor in ocular damage, particularly in the formation of cataracts. Earlier studies pointing to such an effect have been criticized and alternative aetiological hypotheses have been proposed. However, other studies do show an effect of UV exposure on cortical cataract. Concern is also growing that UV may be capable of activating viruses and have immunological effects that might exacerbate infectious disease. Very worrying is the possibility that UV exposure can activate the human immunodeficiency virus which might accelerate the onset AIDS. Any such health effects that have been observed in human populations are the result of exposure to existing, naturally occurring levels of UV radiation. There is, therefore, great concern about the possible exacerbation of these impacts as a result of increased exposure to UV radiation associated with stratospheric ozone depletion. However, any assessment of the nature and scale of such impacts on human health has to deal with several major problems and these are the focus of this paper. There are uncertainties about recent trends in stratospheric ozone and problems in the prediction of future changes.(ABSTRACT TRUNCATED AT 250 WORDS)

journal_name

Parasitology

journal_title

Parasitology

authors

Bentham G

doi

10.1017/s0031182000086108

subject

Has Abstract

pub_date

1993-01-01 00:00:00

pages

S39-46

eissn

0031-1820

issn

1469-8161

journal_volume

106 Suppl

pub_type

杂志文章,评审
  • Rates and intensity of re-infection with human helminths after treatment and the influence of individual, household, and environmental factors in a Brazilian community.

    abstract::This study quantifies the rate and intensity of re-infection with human hookworm and Schistosoma mansoni infection 12 months following successful treatment, and investigates the influence of socio-economic, geographical and environmental factors. A longitudinal study of 642 individuals aged over 5 years was conducted ...

    journal_title:Parasitology

    pub_type: 杂志文章

    doi:10.1017/S0031182011001132

    authors: Cundill B,Alexander N,Bethony JM,Diemert D,Pullan RL,Brooker S

    更新日期:2011-09-01 00:00:00

  • Mechanisms of mortality in Culicoides biting midges due to Haemoproteus infection.

    abstract::We examined the effects of Haemoproteus infection on the survival and pathology caused in the biting midges. Forty-six females of Culicoides impunctatus were exposed experimentally by allowing them to feed on a naturally infected red-backed shrike infected with Haemoproteus lanii (lineage hRB1, gametocytaemia 5·2%). S...

    journal_title:Parasitology

    pub_type: 杂志文章

    doi:10.1017/S0031182016001426

    authors: Bukauskaitė D,Bernotienė R,Iezhova TA,Valkiūnas G

    更新日期:2016-11-01 00:00:00

  • Identification of levamisole resistance markers in the parasitic nematode Haemonchus contortus using a cDNA-AFLP approach.

    abstract::cDNA-AFLP (cDNA-Amplified Fragment Length Polymorphism)-based strategy has been used to identify levamisole (LEV) resistance markers in the nematode Haemonchus contortus. Transcript profiles of adult nematodes from two LEV-resistant and two susceptible isolates were compared. Among the 17 280 transcript-derived fragme...

    journal_title:Parasitology

    pub_type: 杂志文章

    doi:10.1017/S0031182007000030

    authors: Neveu C,Charvet C,Fauvin A,Cortet J,Castagnone-Sereno P,Cabaret J

    更新日期:2007-01-01 00:00:00

  • Tracking a heterosis effect in the field: tadpole resistance to parasites in the water frog hybridogenetic complex.

    abstract::Depending on the extent of evolutionary divergence among parent taxa, hybrids may suffer from a breakdown of co-adapted genes or may conversely exhibit vigour due to the heterosis effect, which confers advantages to increased genetic diversity. That last mechanism could explain the success of hybrids when hybridizatio...

    journal_title:Parasitology

    pub_type: 杂志文章

    doi:10.1017/S0031182009006489

    authors: Planade B,Lena JP,Li H,Plenet S,Guegan JF,Thomas F,Hurtrez-Bousses S,Renaud F,Joly P

    更新日期:2009-08-01 00:00:00

  • Invasion of mature and immature erythrocytes of CBA/Ca mice by a cloned line of Plasmodium chabaudi chabaudi.

    abstract::During the early stages of the primary Plasmodium chabaudi chabaudi AS parasitaemia in CBA/Ca mice this parasite invaded normocytes, but as the parasitaemia developed increasing numbers of parasites were seen within reticulocytes. During and just after peak parasitaemia, as further parasite replication was controlled,...

    journal_title:Parasitology

    pub_type: 杂志文章

    doi:10.1017/s0031182000058583

    authors: Jarra W,Brown KN

    更新日期:1989-10-01 00:00:00

  • Schistosoma mansoni: evidence for a role of serum factors in protecting artificially transformed schistosomula against antibody-mediated killing in vitro.

    abstract::Artificially transformed schistosomula of Schistosoma mansoni develop a consistent but small protection against the lethal effects of antibody plus complement when cultured for 24 h in a chemically defined medium. In contrast, they become rapidly resistant to antibody plus complement, when cultured in the presence of ...

    journal_title:Parasitology

    pub_type: 杂志文章

    doi:10.1017/s0031182000049404

    authors: Tavares CA,Soares RC,Coelho PM,Gazzinelli G

    更新日期:1978-10-01 00:00:00

  • Immune responses to infections with coccidia in chickens: gut hypersensitivity.

    abstract::Sporulated oocysts or oocyst hulls of Eimeria acervulina given via the crop, and oocyst juice or sporozoites inoculated directly into the intestinal lumen, were tested for their effects on the hypersensitivity of the intestines of immunized and susceptible birds. Only viable sporozoites consistently caused an increase...

    journal_title:Parasitology

    pub_type: 杂志文章

    doi:10.1017/s0031182000047132

    authors: Rose ME,Long PL,Bradley JW

    更新日期:1975-12-01 00:00:00

  • IgG reactivities against recombinant Rhoptry-Associated Protein-1 (rRAP-1) are associated with mixed Plasmodium infections and protection against disease in Tanzanian children.

    abstract::A cross-sectional sero-epidemiological study was performed in Magoda, Tanzania, an area where malaria is holoendemic. Blood samples were collected from children (1-4 years) and tested for IgG antibody reactivity against 2 recombinant protein fragments of Plasmodium falciparum Rhoptry-Associated Protein-1 (rRAP-1). The...

    journal_title:Parasitology

    pub_type: 杂志文章

    doi:10.1017/s0031182099004825

    authors: Alifrangis M,Lemnge MM,Moon R,Theisen M,Bygbjerg I,Ridley RG,Jakobsen PH

    更新日期:1999-10-01 00:00:00

  • A middle-repetitive DNA sequence element in the sheep parasitic nematode, Trichostrongylus colubriformis.

    abstract::A novel repetitive DNA sequence in the sheep parasitic nematode Trichostrongylus colubriformis was cloned and sequenced. A 1.1 kb repetitive sequence (Tc15) which hybridized with DNA from T. colubriformis but not with DNA from two other parasitic nematodes, Haemonchus contortus and Ostertagia circumcincta, or sheep wa...

    journal_title:Parasitology

    pub_type: 杂志文章

    doi:10.1017/s0031182000078379

    authors: Callaghan MJ,Beh KJ

    更新日期:1994-09-01 00:00:00

  • The capacity of the fungus Duddingtonia flagrans to prevent strongyle infections in foals on pasture.

    abstract::A field trial was conducted to evaluate the potential of the nematode-destroying fungus Duddingtonia flagrans to control free-living stages of horse strongyles. In late Spring 2 groups of horses (yearlings) with mixed infections of strongyles were allowed to contaminate 2 equal-sized pastures. One of the groups (F) re...

    journal_title:Parasitology

    pub_type: 杂志文章

    doi:10.1017/s003118200006621x

    authors: Larsen M,Nansen P,Grøndahl C,Thamsborg SM,Grønvold J,Wolstrup J,Henriksen SA,Monrad J

    更新日期:1996-07-01 00:00:00

  • The effects of age, temperature, light quantity and wavelength on the swimming behaviour of the cercariae of Cryptocotyle lingua (Digenea: Heterophyidae).

    abstract::Laboratory experiments indicated that the active life-span of the cercariae of Cryptocotyle lingua was temperature-dependent. An increase in water temperature and population age both correlated with a tendency for the organisms to become decaudate. The larvae were strongly photoresponsive to lateral light but with tim...

    journal_title:Parasitology

    pub_type: 杂志文章

    doi:10.1017/s0031182000073789

    authors: Rea JG,Irwin SW

    更新日期:1992-08-01 00:00:00

  • Capture and penetration processes of the free-living juveniles of Trichostrongylus colubriformis (Nematoda) by the nematophagous fungus, Arthrobotrys oligospora.

    abstract::The nematode-trapping fungus Arthrobotrys oligospora traps and invades all the free-living juvenile stages of the trichostrongyle nematode Trichostrongylus colubriformis. The processes of capture and invasion of the 1st-stage juveniles are described using differential interference contrast optics and 3-D reconstructio...

    journal_title:Parasitology

    pub_type: 杂志文章

    doi:10.1017/s0031182000079798

    authors: Murray DS,Wharton DA

    更新日期:1990-08-01 00:00:00

  • Babesia microti and Borrelia bissettii transmission by Ixodes spinipalpis ticks among prairie voles, Microtus ochrogaster, in Colorado.

    abstract::An endemic transmission cycle of Babesia microti was discovered in Colorado in the foothills of the Rocky Mountains. B. microti were found by PCR in 4 of 25 Ixodes spinipalpis tick pools tested (a 3.2 % minimum infection rate) and in 87% (13 of 15) of Microtus ochrogaster (the prairie vole) spleen and blood samples. U...

    journal_title:Parasitology

    pub_type: 杂志文章

    doi:

    authors: Burkot TR,Schneider BS,Pieniazek NJ,Happ CM,Rutherford JS,Slemenda SB,Hoffmeister E,Maupin GO,Zeidner NS

    更新日期:2000-12-01 00:00:00

  • Molecular characterization of 5S ribosomal RNA genes and transcripts in the protozoan parasite Leishmania major.

    abstract::Eukaryotic 5S rRNA, synthesized by RNA polymerase III (Pol III), is an essential component of the large ribosomal subunit. Most organisms contain hundreds of 5S rRNA genes organized into tandem arrays. However, the genome of the protozoan parasite Leishmania major contains only 11 copies of the 5S rRNA gene, which are...

    journal_title:Parasitology

    pub_type: 杂志文章

    doi:10.1017/S0031182016001712

    authors: Moreno-Campos R,Florencio-Martínez LE,Nepomuceno-Mejía T,Rojas-Sánchez S,Vélez-Ramírez DE,Padilla-Mejía NE,Figueroa-Angulo E,Manning-Cela R,Martínez-Calvillo S

    更新日期:2016-12-01 00:00:00

  • Gametocyte sex ratio of a malaria parasite: response to experimental manipulation of parasite clonal diversity.

    abstract::Sex ratio theory posits that the adaptive proportion of male to female gametocytes of a malaria parasite within the vertebrate host depends on the degree of inbreeding within the vector. Gametocyte sex ratio could be phenotypically flexible, being altered based on the infection's clonal diversity, and thus likely inbr...

    journal_title:Parasitology

    pub_type: 杂志文章

    doi:10.1017/s0031182003004207

    authors: Osgood SM,Schall JJ

    更新日期:2004-01-01 00:00:00

  • Myxozoans as biological tags for stock identification of the Argentine hake, Merluccius hubbsi (Gadiformes: Merlucciidae).

    abstract::Myxozoans have been successfully used as tags for fish stock identification around the world. However, few studies using myxozoan tags have been carried out in the Southern Atlantic, a region with complex oceanography that constitutes a potentially suitable scenario for testing the utility of myxozoans as indicators. ...

    journal_title:Parasitology

    pub_type: 杂志文章

    doi:10.1017/S0031182016000226

    authors: Cantatore DM,Irigoitia MM,Holzer AS,Timi JT

    更新日期:2016-05-01 00:00:00

  • Substrate specificity of the neutral sphingomyelinase from Trypanosoma brucei.

    abstract::The kinetoplastid parasite Trypanosoma brucei causes African trypanosomiasis in both humans and animals. Infections place a significant health and economic burden on developing nations in sub-Saharan Africa, but few effective anti-parasitic treatments are currently available. Hence, there is an urgent need to identify...

    journal_title:Parasitology

    pub_type: 杂志文章

    doi:10.1017/S0031182018001853

    authors: Dickie EA,Young SA,Smith TK

    更新日期:2019-04-01 00:00:00

  • Purification and characterization of a 47 kDa protease from Schistosoma mansoni cercarial secretion.

    abstract::Fractionation of Schistosoma mansoni cercariae gland secretion on a Sephadex G-150 column followed by a Superose-12 column in an FPLC system, isolated a 47 kDa protease which migrated as a single band on SDS-PAGE gels. A monoclonal antibody (MAb) was produced which recognizes only the 47 kDa protease, and an immuno-af...

    journal_title:Parasitology

    pub_type: 杂志文章

    doi:10.1017/s0031182000074138

    authors: Chavez-Olortegui C,Resende M,Tavares CA

    更新日期:1992-10-01 00:00:00

  • Human portal serum stimulates cell proliferation in immature Schistosoma mansoni.

    abstract::Schistosomula of Schistosoma mansoni were incubated in RPMI 1640 medium containing 10% fetal calf serum, 10% human portal venous or 10% human peripheral venous sera in the presence of bromodeoxyuridine (BrdU) in order to measure differences in cell proliferation. The rates of cell proliferation as expressed by BrdU la...

    journal_title:Parasitology

    pub_type: 杂志文章

    doi:10.1017/s0031182098003096

    authors: Shaker YM,Wu CH,el-Shobaki FA,Ashour E,Khattab HM,Draz HM,Kamel R,Wu GY

    更新日期:1998-10-01 00:00:00

  • Parasite biodiversity and its determinants in coastal marine teleost fishes of Brazil.

    abstract::Recent studies of the forces behind the diversification of parasite assemblages have shed light on many aspects of parasite biodiversity. By using only parasite species richness as their measure of diversity, however, previous investigations have ignored the relatedness among parasite species and the taxonomic structu...

    journal_title:Parasitology

    pub_type: 杂志文章

    doi:10.1017/s0031182004005050

    authors: Luque JL,Mouillot D,Poulin R

    更新日期:2004-06-01 00:00:00

  • An egg-adapted (attenuated) line of Eimeria necatrix: further studies on its reproduction, pathogenicity and immunogenicity.

    abstract::An egg-adapted line of Eimeria necatrix has now been passaged 40 times in the chorio-allantoic membranes of embryonated eggs. Between the 21st and 40th passage in eggs the parasite was subjected to a selection for precocious development, and its pre-patent period in this host is now 123-125 h. The parasite continued t...

    journal_title:Parasitology

    pub_type: 杂志文章

    doi:10.1017/s0031182000044784

    authors: Shirley MW,Bellatti MA,Millard BJ

    更新日期:1982-04-01 00:00:00

  • Four new species of KudoaMeglitsch, 1947 (Myxosporea: Multivalvulida) from Australia with recommendations for species descriptions in the Kudoidae.

    abstract::Kudoid parasites are significant pathogens of marine fish. In the past, specific identification has been difficult due to a paucity of detailed morphological and biological information provided in the original description of some species. However, the introduction of DNA analysis has dramatically improved diagnosis. F...

    journal_title:Parasitology

    pub_type: 杂志文章

    doi:10.1017/S0031182009991557

    authors: Burger MA,Adlard RD

    更新日期:2010-04-01 00:00:00

  • Isolation and characterization of secretions from the plant-parasitic nematode Globodera pallida.

    abstract::Electrophoresis of secretions collected from Globodera pallida revealed a smeared region between 25 and 50 kDa, and a single band of < 20 kDa. The secretions were used to raise an antiserum (LW1). Immunoblotting of parasite homogenates with LW1 differentiated G. pallida from its sibling species G. rostochiensis and re...

    journal_title:Parasitology

    pub_type: 杂志文章

    doi:10.1017/s0031182097001443

    authors: Duncan LH,Robertson L,Robertson WM,Kusel JR

    更新日期:1997-10-01 00:00:00

  • Glycans with N-acetyllactosamine type 2-like residues covering adult Schistosoma mansoni, and glycomimesis as a putative mechanism of immune evasion.

    abstract::Glycans at the surface of adult Schistosoma mansoni were investigated with gold-labelled lectins. The fragile complex of the glycans with the outer membranes could be preserved for electron microscopy by avoiding extensive pre-fixation with aldehydes and by introducing osmium-ferrocyanide as a membrane fixative. Male ...

    journal_title:Parasitology

    pub_type: 杂志文章

    doi:10.1017/s0031182000081877

    authors: Schmidt J

    更新日期:1995-09-01 00:00:00

  • DNA base composition of filarial nematodes.

    abstract::We have determined the molar content of guanine + cytosine (GC content) of DNA of the filarial nematode (Brugia malayi, Brugia pahangi and Dirofilaria imitis) and of the free-living soil nematodes Caenorhabditis elegans and have analysed the DNA for the presence of methylcytosine. Two independent methods, thermal dena...

    journal_title:Parasitology

    pub_type: 杂志文章

    doi:10.1017/s0031182000066750

    authors: Rothstein N,Stoller TJ,Rajan TV

    更新日期:1988-08-01 00:00:00

  • Subtype analysis of Cryptosporidium parvum isolates from calves on farms around Belgrade, Serbia and Montenegro, using the 60 kDa glycoprotein gene sequences.

    abstract::Cryptosporidium parvum is composed of multiple subtypes, which appear to be zoonotic or anthroponotic. Therefore, in order to understand the molecular epidemiology of this species and to control the zoonotic transmission, it is essential to identify the isolates at the subtype level. In the present study, 60.2% of 103...

    journal_title:Parasitology

    pub_type: 杂志文章

    doi:10.1017/S0031182006001508

    authors: Misic Z,Abe N

    更新日期:2007-03-01 00:00:00

  • Purification of a 64 kDa antigen from Trypanosoma evansi that exhibits cross-reactivity with Trypanosoma vivax.

    abstract::Trypanosoma evansi and Trypanosoma vivax are the most extensively distributed trypanosomes responsible for diseases in livestock. Western blot and indirect immunofluorescence assays revealed a high immunological cross-reaction between these two parasites. An antigen with an apparent molecular mass of 64 kDa (p64), whi...

    journal_title:Parasitology

    pub_type: 杂志文章

    doi:10.1017/s0031182001001214

    authors: Uzcanga G,Mendoza M,Aso PM,Bubis J

    更新日期:2002-03-01 00:00:00

  • Saccharomyces boulardii inhibits the expression of pro-inflammatory cytokines and inducible nitric oxide synthase genes in the colonic mucosa of rats experimentally-infected with Blastocystis subtype-3 cysts.

    abstract::Blastocystis spp. is the most frequent infectious unicellular, luminal parasite in all species of animals and humans. It has been linked to diarrhoea and irritable bowel syndrome. Saccharomyces boulardii (Sb) is a widely used probiotic that previously showed efficacy against several intestinal pathogens. The aim of th...

    journal_title:Parasitology

    pub_type: 杂志文章

    doi:10.1017/S0031182019000696

    authors: Méabed EMH,Abdelhafez DN,Abdelaliem YF

    更新日期:2019-10-01 00:00:00

  • Carbohydrate inhibition of Biomphalaria glabrata embryonic (Bge) cell adhesion to primary sporocysts of Schistosoma mansoni.

    abstract::Due to shared characteristics with snail haemocytes, the Biomphalaria glabrata embryonic (Bge) cell line has been used as a model in vitro system for the study of snail-trematode interactions. In this study, Bge cells were used to characterize the adherence of snail host cells to schistosome primary sporocysts, and to...

    journal_title:Parasitology

    pub_type: 杂志文章

    doi:

    authors: Castillo MG,Yoshino TP

    更新日期:2002-12-01 00:00:00

  • Development of a sensitive immunochromatographic kit using fluorescent silica nanoparticles for rapid serodiagnosis of amebiasis.

    abstract::We have previously shown that the C-terminal region of the intermediate subunit of Entamoeba histolytica galactose- and N-acetyl-D-galactosamine-inhibitable lectin (C-Igl) is a useful antigen for serodiagnosis of amebiasis. An immunochromatographic kit was developed using fluorescent silica nanoparticles coated with C...

    journal_title:Parasitology

    pub_type: 杂志文章

    doi:10.1017/S0031182018000690

    authors: Tachibana H,Kakino A,Kazama M,Feng M,Asai S,Umezawa K,Nozaki T,Makiuchi T,Kamada T,Watanabe H,Horiki N,Cheng X,Masuda G

    更新日期:2018-12-01 00:00:00