Saccharomyces boulardii inhibits the expression of pro-inflammatory cytokines and inducible nitric oxide synthase genes in the colonic mucosa of rats experimentally-infected with Blastocystis subtype-3 cysts.

abstract：:During a longitudinal study investigating the dynamics of malaria in Ugandan lakeshore communities, a consistently high malaria prevalence was observed in young children despite regular treatment. To explore the short-term performance of artemether-lumefantrine (AL), a pilot investigation into parasite carriage after ...

journal_title：Parasitology

authors： Betson M,Sousa-Figueiredo JC,Atuhaire A,Arinaitwe M,Adriko M,Mwesigwa G,Nabonge J,Kabatereine NB,Sutherland CJ,Stothard JR

更新日期：2014-12-01 00:00:00

abstract：:Trypanosoma brucei is the causative agent of African sleeping sickness in humans and one of several pathogens that cause the related veterinary disease Nagana. A complex co-evolution has occurred between these parasites and primates that led to the emergence of trypanosome-specific defences and counter-measures. The f...

journal_title：Parasitology

authors： Capewell P,Cooper A,Clucas C,Weir W,Macleod A

更新日期：2015-02-01 00:00:00

abstract：:The behavioural responses of Onchocerca lienalis microfilariae (mf) to tissue factors of the surrogate black fly host, Simulium vittatum, were studied using a novel in vitro bioassay. Mf accumulated towards thoracic tissues to a density 4 times higher than towards abdominal tissues, despite the larger surface area and...

journal_title：Parasitology

authors： Lehmann T,Cupp SM,Cupp WE

更新日期：1995-04-01 00:00:00

abstract：:With the increased availability of multilocus sequence data, the lack of concordance of gene trees estimated for independent loci has focused attention on both the biological processes producing the discord and the methodologies used to estimate phylogenetic relationships. What has emerged is a suite of new analytical...

journal_title：Parasitology

authors： Knowles LL,Klimov PB

更新日期：2011-11-01 00:00:00

abstract：:A double antibody sandwich ELISA technique has been developed for detection of antigens of African trypanosomes present in the sera of infected mammals. The assay uses a high titre, high affinity rabbit antiserum made to purified membranes of procyclic trypanosomes as "capture" reagent and a mixture of three biotin-la...

journal_title：Parasitology

authors： Liu MK,Pearson TW

更新日期：1987-10-01 00:00:00

abstract：:Genome sequencing has greatly contributed to our understanding of parasitic protozoa. This is particularly the case for Cryptosporidium species (phylum Apicomplexa) which are difficult to propagate. Because of their polymorphic nature, simple sequence repeats have been used extensively as genotypic markers to differen...

journal_title：Parasitology

authors： Widmer G

更新日期：2018-08-01 00:00:00

abstract：:Thirty-one stocks of Trypanosoma cruzi, the agent of Chagas disease, representative of the genetic variability of the 2 principal lineages, that subdivide T. cruzi, were selected on the basis of previous multilocus enzyme electrophoresis analysis using 21 loci. Analyses were performed with lower numbers of loci to exp...

journal_title：Parasitology

authors： Breniere SF,Barnabe C,Bosseno MF,Tibayrenc M

更新日期：2003-09-01 00:00:00

abstract：:Theileria annulata infects and reversibly transforms bovine leucocytes. The parasite-transformed cells are immortalized, metastatic and express a number of metalloproteinases including matrix metalloproteinase 9 which they secrete. All the metalloproteinases observed on substrate gels are inhibited by tissue inhibitor...

journal_title：Parasitology

authors： Adamson RE,Hall FR

更新日期：1996-11-01 00:00:00

abstract：:Changes in the cardiac beta-adrenergic system in early stages of Trypanosoma cruzi infection have been described. Here, we studied an early (135 days post-infection-p.i.) and a late stage (365 days p.i.) of the cardiac chronic form of the experimental infection (Tulahuen or SGO-Z12 strains), determining plasma epineph...

journal_title：Parasitology

authors： Lo Presti MS,Rivarola HW,Fernández AR,Enders JE,Levin G,Fretes R,Cerban FM,Garrido VV,Paglini-Oliva P

更新日期：2009-07-01 00:00:00

abstract：:To investigate the quantitative distribution of Plasmodiumfalciparum gametocytes into the vector bloodmeal, Anopheles arabiensis mosquitoes were fed on 3 volunteers naturally infected with gametocytes. The content of each mosquito midgut was smeared on a microscope slide and Giemsa stained. The distribution of gametoc...

journal_title：Parasitology

authors： Pichon G,Awono-Ambene HP,Robert V

更新日期：2000-08-01 00:00:00

abstract：:An hypothesis is presented to explain the red cell lysis which accompanies an acute malarial infection, as well as the mode of action of certain schizonticidal drugs in the quinoline and acridine series. Quinine and a number of other antimalarial drugs have been found to counteract the inhibition by protein of fatty a...

journal_title：Parasitology

authors： Laser H,Kemp P,Miller N,Lander D,Klein R

更新日期：1975-10-01 00:00:00

abstract：:Previous studies of mating interactions between schistosome species from different evolutionary lineages in mice showed that mating is not random: heterospecific pairs form but, given the choice, the preference is for homospecific partners. Mating competition and change of mate were also demonstrated. Schistosoma mans...

journal_title：Parasitology

authors： Cosgrove CL,Southgate VR

更新日期：2002-09-01 00:00:00

abstract：:The first rigorous proof applicable to the migration pathway of an infective juvenile macroparasite inside its host is presented. Third-stage larvae of a homogonic strain of Strongyloides ratti applied in exact doses of less than 20 to the skin of the flank of young rats were recovered 16-40 h later in the naso-fronta...

journal_title：Parasitology

authors： Tindall NR,Wilson PA

更新日期：1988-06-01 00:00:00

abstract：:Antibodies against variable antigens expressed on the surface of Plasmodium falciparum-infected erythrocytes are believed to be important for protection against malaria. A target for these antibodies is the P. falciparum erythrocyte membrane protein 1, PfEMP1, which is encoded by around 50 var genes and undergoes clon...

journal_title：Parasitology

authors： Giha HA,Staalsoe T,Dodoo D,Elhassan IM,Roper C,Satti GM,Arnot DE,Hviid L,Theander TG

更新日期：1999-07-01 00:00:00

abstract：:Infection with the endosymbiotic bacteria Wolbachia is widespread in filarial nematodes. Previous studies have suggested concordance between the phylogeny of Wolbachia with that of their nematode hosts. However, there is only one published molecular phylogenetic study of filarial species, based on the 5S rRNA gene spa...

journal_title：Parasitology

authors： Casiraghi M,Anderson TJ,Bandi C,Bazzocchi C,Genchi C

更新日期：2001-01-01 00:00:00

abstract：:Amoebiasis, infection by the protozoan parasite Entamoeba histolytica, remains a global health problem, despite the availability of effective treatment. While improved sanitation could lead to the eradication of this disease, it is unlikely that this will occur worldwide in the foreseeable future; thus alternative mea...

journal_title：Parasitology

authors： Stanley SL Jr

更新日期：2006-01-01 00:00:00

abstract：:The accumulation of the trypanocide isometamidium chloride (Samorin, RMB Animal Health Ltd., UK) by a range of clones of Trypanosoma congolense with varying sensitivity to the drug, was measured by methods based on the fluorescence of isometamidium. Fluorescence microscopy and flow cytometry showed a reduction in drug...

journal_title：Parasitology

authors： Sutherland IA,Peregrine AS,Lonsdale-Eccles JD,Holmes PH

更新日期：1991-10-01 00:00:00

abstract：:Promastigotes of Leishmania braziliensis panamensis absorbed the purines adenine, hypoxanthine, adenosine and inosine by a combination of diffusion and mediated components. When the uptake rates for these substrates were corrected for diffusion and compared, the purine bases adenine and hypoxanthine were transported a...

journal_title：Parasitology

authors： Hansen BD,Perez-Arbelo J,Walkony JF,Hendricks LD

更新日期：1982-10-01 00:00:00

abstract：:The glycogen stores of adult Schistosoma mansoni worms could be labelled by incubation of the worms, after an initial reduction of their glycogen content, in the presence of [6-14C]glucose. Subsequent breakdown of the labelled glycogen by the parasite revealed that glycogen was degraded to lactate and carbon dioxide. ...

journal_title：Parasitology

authors： Tielens AG,Celik C,Van den Heuvel JM,Elfring RH,Van den Bergh SG

更新日期：1989-02-01 00:00:00

abstract：:The diversity and prevalence of malaria parasites of the genera Plasmodium and Haemoproteus were determined in the globally-threatened Aquatic Warbler Acrocephalus paludicola. Birds were sampled during migration in Portugal and at the wintering quarters in Senegal and parasites were detected using molecular methods. O...

journal_title：Parasitology

authors： Neto JM,Pérez-Rodríguez A,Haase M,Flade M,Bensch S

更新日期：2015-08-01 00:00:00

abstract：:Solid experimental evidence indicates that EBA-175 is used as a ligand by the Plasmodium falciparum merozoite to bind to human RBC, via different binding processing fragments. Using synthetic peptides and specific receptor-ligand interaction methodology, we have identified 6 high-activity binding sequences from the EB...

journal_title：Parasitology

authors： Rodriguez LE,Urquiza M,Ocampo M,Suarez J,Curtidor H,Guzman F,Vargas LE,Triviños M,Rosas M,Patarroyo ME

更新日期：2000-03-01 00:00:00

abstract：:The effect of different incubation media and of temperature on the induction of water sensitivity has been investigated in intact and tailless Schistosoma mansoni cercariae. Removal of the cercarial tail by vortex stirring and elevation of the temperature of the medium from 27 to 37 degrees C resulted in the rapid ons...

journal_title：Parasitology

authors： Ramalho-Pinto FJ,Gazzinelli G,Howells RE,Pellegrino J

更新日期：1975-08-01 00:00:00

abstract：:Oligosaccharides are broadly present on Leishmania cell surfaces. They can be useful for the leishmaniases diagnosis and also helpful in identifying new cell markers for the disease. The disaccharide Galα1-3Galβ is the immunodominant saccharide in Leishmania cell surface and is the unique non-reducing terminal glycosp...

journal_title：Parasitology

authors： de Souza LMB,Thomaz Soccol V,Petterle RR,Bates MD,Bates PA

更新日期：2018-12-01 00:00:00

abstract：:Schistosoma mansoni depends for its survival on glycolysis. Two glycolytic enzymes, glyceraldehyde-3P-dehydrogenase and triose-phosphate dehydrogenase, found in both the adult and schistosomular tegument, have been reported to confer partial protection against cercarial infection. This paper describes the immunogenic ...

journal_title：Parasitology

authors： Mansour JM,McCrossan MV,Bickle QD,Mansour TE

更新日期：2000-05-01 00:00:00

abstract：:Sodium fluoride (NaF) is an anion that has been previously shown to block the moulting process of Ascaris suum larvae. This study describes moulting and development-specific protein expression profiles of A. suum lung-stage L3 (AsLL3) following NaF exposure. AsLL3s cultured in the presence or absence of NaF were prepa...

journal_title：Parasitology

authors： Islam MK,Miyoshi T,Yamada M,Alim MA,Huang X,Motobu M,Tsuji N

更新日期：2006-10-01 00:00:00

abstract：:A 196 bp fragment of cloned kinetoplast (k) DNA of Leishmania infantum has been sequenced and shown to be diagnostic for this species. The DNA from 10(4)-10(5) promastigotes was routinely and specifically detected in crude dot blots of whole cells lysed in situ, and there was no cross-hybridization with 10(6) cells of...

journal_title：Parasitology

authors： Gramiccia M,Smith DF,Angelici MC,Ready PD,Gradoni L

更新日期：1992-08-01 00:00:00

abstract：:Adult Onchocerca volvulus worms obtained by enzyme digestion from nodules of infected Mexicans were radio-isotope labelled by the chloramine-T or Bolton-Hunter methods. No antigenic determinants were detected in extracts of worms labelled by the chloramine-T method but 3 antigens were detected in extracts of the Bolto...

journal_title：Parasitology

authors： Philipp M,Gómez-Priego A,Parkhouse RM,Davies MW,Clark NW,Ogilvie BM,Beltrán-Hernández F

更新日期：1984-10-01 00:00:00

abstract：:African sleeping sickness is a parasitic disease transmitted through the bites of tsetse flies of the genus Glossina. We constructed mechanistic models for the basic reproduction number, R0, of Trypanosoma brucei gambiense and Trypanosoma brucei rhodesiense, respectively the causative agents of West and East African h...

journal_title：Parasitology

authors： Davis S,Aksoy S,Galvani A

更新日期：2011-04-01 00:00:00

abstract：:As has been shown previously, immunologically intact mice with patent Schistosoma mansoni infections had a significantly lower mean platelet number than intact uninfected mice (P<0.0001). However, platelet numbers in T-cell deprived mice with patent infections were not significantly different from those in uninfected ...

journal_title：Parasitology

authors： Stanley RG,Ngaiza JR,Atieno E,Jell G,Francklow K,Jackson CL,Parry H,Doenhoff MJ

更新日期：2003-03-01 00:00:00

abstract：:Cysteine proteases of pathogenic protozoan parasites play pivotal roles in the life cycle of parasites, but strict regulation of their activities is also essential for maintenance of parasite physiology and interaction with hosts. In this study, we identified and characterized cryptostatin, a novel inhibitor of cystei...

journal_title：Parasitology

authors： Kang JM,Ju HL,Yu JR,Sohn WM,Na BK

更新日期：2012-07-01 00:00:00