Immune responses to infections with coccidia in chickens: gut hypersensitivity.

Abstract:

:Sporulated oocysts or oocyst hulls of Eimeria acervulina given via the crop, and oocyst juice or sporozoites inoculated directly into the intestinal lumen, were tested for their effects on the hypersensitivity of the intestines of immunized and susceptible birds. Only viable sporozoites consistently caused an increase in the permeability of the immunized intestine to macromolecules, shown by the leakage of intravenously injected dye. Repulsion of epithelium and disruption of the villi were seen more often in immunized than in susceptible chickens but there was no correlation with treatment or with dye leakage. The hypersensitive response of immune intestines challenged with a heterologous organism was approximately half as intense as the response to homologous challenge. The significance of these findings in relation to immunity to coccidiosis is discussed.

journal_name

Parasitology

journal_title

Parasitology

authors

Rose ME,Long PL,Bradley JW

doi

10.1017/s0031182000047132

subject

Has Abstract

pub_date

1975-12-01 00:00:00

pages

357-68

issue

3

eissn

0031-1820

issn

1469-8161

journal_volume

71

pub_type

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