Selection and evolution of virulence in bacteria: an ecumenical excursion and modest suggestion.

Abstract:

:Why do parasites kill their hosts? During this past decade, research in three different areas; evolutionary ecology, medical microbiology, and population genetics has provided theory and data that address this and related questions of selection and the evolution and maintenance of parasite virulence. A general theory of parasite-host coevolution and the conditions for selection to favour parasite virulence has been put forth. Considerable advances have been made in elucidating the mechanisms of pathogenicity and inheritance of virulence in bacteria. The population genetic structure and the relationship between pathogenic and non-pathogenic forms has been determined for a number of species of bacteria. We critically review these developments and their implications for questions of selection and the evolution and maintenance of virulence in bacteria. We postulate how selection may operate on specific types of bacterial virulence and present a general protocol to experimentally test hypotheses concerning selection and the evolution of virulence in bacteria.

journal_name

Parasitology

journal_title

Parasitology

authors

Levin BR,Svanborg Edén C

doi

10.1017/s0031182000073054

subject

Has Abstract

pub_date

1990-01-01 00:00:00

pages

S103-15

eissn

0031-1820

issn

1469-8161

journal_volume

100 Suppl

pub_type

杂志文章,评审
  • Discrimination between six species of Theileria using oligonucleotide probes which detect small subunit ribosomal RNA sequences.

    abstract::The complete small subunit ribosomal RNA (srRNA) gene of Theileria parva was cloned and sequenced. Two primers were designed which permitted the specific amplification of part of the Theileria srRNA gene from Theileria-infected cell line samples which were predominantly (> 95%) bovine DNA. The sequence of the central ...

    journal_title:Parasitology

    pub_type: 杂志文章

    doi:10.1017/s0031182000067263

    authors: Allsopp BA,Baylis HA,Allsopp MT,Cavalier-Smith T,Bishop RP,Carrington DM,Sohanpal B,Spooner P

    更新日期:1993-08-01 00:00:00

  • Responses to larval Taenia taeniaeformis in mice with severe combined immunodeficiency (scid).

    abstract::Responses to Taenia taeniaeformis infection were studied in mice with severe combined immunodeficiency (scid), which lack functional T and B lymphocytes. In the early phase of infection, accumulation of polymorphonuclear leucocytes (PML) occurred around the larvae in the liver of scid mice and their immunocompetent co...

    journal_title:Parasitology

    pub_type: 杂志文章

    doi:10.1017/s0031182000061825

    authors: Ishiwata K,Oku Y,Ito M,Kamiya M

    更新日期:1992-04-01 00:00:00

  • Vaccines for amoebiasis: barriers and opportunities.

    abstract::Amoebiasis, infection by the protozoan parasite Entamoeba histolytica, remains a global health problem, despite the availability of effective treatment. While improved sanitation could lead to the eradication of this disease, it is unlikely that this will occur worldwide in the foreseeable future; thus alternative mea...

    journal_title:Parasitology

    pub_type: 杂志文章,评审

    doi:10.1017/S003118200600182X

    authors: Stanley SL Jr

    更新日期:2006-01-01 00:00:00

  • The mannitol cycle in Eimeria.

    abstract::A metabolic pathway known as the mannitol cycle has been identified in Eimerian parasites. The pathway is a shunt off of the glycolytic pathway at fructose-6-phosphate (F6P). Two enzymes convert F6P to mannitol and two other enzymes are responsible for converting mannitol back to F6P when it is utilized. Although the ...

    journal_title:Parasitology

    pub_type: 杂志文章,评审

    doi:

    authors: Schmatz DM

    更新日期:1997-01-01 00:00:00

  • Microgametogony of Sarcocystis hirsuta in the intestine of the cat.

    abstract::The development of microgamonts was studied in the small intestine of a 2-day-old cat after oral inoculation with 10(7) bradyzoites of Sarcocystis hirsuta. The cat was given bradyzoites in 2 doses at 2 h apart and killed 4 h later. Gamonts were seen in parasitophorous vacuoles of goblet cells in the epithelium of the ...

    journal_title:Parasitology

    pub_type: 杂志文章

    doi:10.1017/s0031182000057115

    authors: Dubey JP

    更新日期:1983-02-01 00:00:00

  • The serotoninergic, cholinergic and peptidergic components of the nervous system in the monogenean parasite, Diclidophora merlangi: a cytochemical study.

    abstract::Confocal scanning laser microscopy has been employed with immunocytochemical techniques to map the distribution of serotoninergic and peptidergic components in the nervous system of the monogenean gill-parasite, Diclidophora merlangi; results are compared with the distribution of cholinergic components, following hist...

    journal_title:Parasitology

    pub_type: 杂志文章

    doi:10.1017/s0031182000061266

    authors: Maule AG,Halton DW,Johnston CF,Shaw C,Fairweather I

    更新日期:1990-04-01 00:00:00

  • Detection of viruses in livestock.

    abstract::Diseases caused by viruses are a constant and major problem for livestock production world wide. The diseases range from highly contagious acute forms with high mortality, to chronic disabling diseases with an insidious effect on production. Such diseases cannot be regarded as static in nature due to the highly mutabl...

    journal_title:Parasitology

    pub_type: 杂志文章,评审

    doi:10.1017/s0031182099004199

    authors: Crowther JR

    更新日期:1998-01-01 00:00:00

  • Mathematical models of parasite responses to host immune defences.

    abstract::We examine the evolution of microparasites in response to the immune system of vertebrate hosts. We first describe a simple model for an acute infection. This model suggests that the within-host dynamics of the microparasite will be a 'race' between parasite multiplication and a clonally expanding response by the host...

    journal_title:Parasitology

    pub_type: 杂志文章,评审

    doi:10.1017/s003118209700200x

    authors: Antia R,Lipsitch M

    更新日期:1997-01-01 00:00:00

  • Antiparasitic effects of ethanolic extracts of Piper arboreum and Jatropha gossypiifolia leaves on cercariae and adult worms of Schistosoma mansoni.

    abstract::New treatment strategies for schistosomiasis should be evaluated, since resistant strains to the only available drug, Praziquantel, have already been described. Thus, we demonstrated antiparasitic effects of ethanolic extracts of Jatropha gossypiifolia and Piper arboreum on cercariae and adult worms of Schistosoma man...

    journal_title:Parasitology

    pub_type: 杂志文章

    doi:10.1017/S003118202000181X

    authors: da Silva Alves RR,Mendes Rodrigues JG,Teles-Reis A,Araújo Nogueira R,Correia Lima Licá I,Sampaio Lira MG,da Silva Alves R,Silva-Souza N,Aguiar Dos Santos Andrade TJ,Silva Miranda G

    更新日期:2020-12-01 00:00:00

  • Repeated infection of cats with Brugia pahangi: parasitological observations.

    abstract::Cats were repeatedly inoculated with infective larvae of Brugia pahangi. On parasitological grounds they could be divided into 5 groups. Group I--most cats (some 70%) became microfilaraemic (mf+) and retained high levels of microfilariae (mf) in their blood for over 2 years. In some Group I cats mf counts stabilized a...

    journal_title:Parasitology

    pub_type: 杂志文章

    doi:10.1017/s0031182000063666

    authors: Denham DA,Medeiros F,Baldwin C,Kumar H,Midwinter IC,Birch DW,Smail A

    更新日期:1992-06-01 00:00:00

  • The molecular systematics of blowflies and screwworm flies (Diptera: Calliphoridae) using 28S rRNA, COX1 and EF-1α: insights into the evolution of dipteran parasitism.

    abstract::The Calliphoridae include some of the most economically significant myiasis-causing flies in the world - blowflies and screwworm flies - with many being notorious for their parasitism of livestock. However, despite more than 50 years of research, key taxonomic relationships within the family remain unresolved. This st...

    journal_title:Parasitology

    pub_type: 杂志文章

    doi:10.1017/S0031182011001089

    authors: McDonagh LM,Stevens JR

    更新日期:2011-11-01 00:00:00

  • The formation of surface membrane vesicles from schistosomula of Schistosoma mansoni.

    abstract::Intact surface membrane vesicles were obtained and purified from the schistosomula of Schistosoma mansoni. The method of preparation of the vesicles involved treating the schistosomula in a buffered high salt medium for 1 h at 4 degrees C (Step 1), and then for 1 h at 25-37 degrees C (Step 2). Vesicles were formed fro...

    journal_title:Parasitology

    pub_type: 杂志文章

    doi:10.1017/s0031182000056717

    authors: Kusel JR,Gazzinelli G,Colley DG,de Souza CP,Cordeiro MN

    更新日期:1984-12-01 00:00:00

  • Association and predatory capacity of fungi Pochonia chlamydosporia and Arthrobotrys cladodes in the biological control of parasitic helminths of bovines.

    abstract::Nematophagous fungi are used in the biological control of the parasitic helminths of animals and plants. The association of ovicidal and predator nematophagous fungi may present a complementary and increased action on the biological control of helminths. Joint growth compatibility and predation tests were carried out ...

    journal_title:Parasitology

    pub_type: 杂志文章

    doi:10.1017/S003118201900060X

    authors: Vieira ÍS,Oliveira IC,Campos AK,Araújo JV

    更新日期:2019-09-01 00:00:00

  • Taenia crassiceps: in vivo and in vitro models.

    abstract::Taenia crassiceps is a cestode parasite of wild and domestic animals that rarely affects humans; it has been widely used as an experimental model. The asexual proliferation by budding is a useful attribute of T. crassiceps cysticerci, which allows the various strains to be maintained indefinitely in the peritoneal cav...

    journal_title:Parasitology

    pub_type: 杂志文章,评审

    doi:10.1017/S0031182009991442

    authors: Willms K,Zurabian R

    更新日期:2010-03-01 00:00:00

  • To avoid or eliminate: cestode infections in copepods.

    abstract::The outcome of a parasite infection is the result of the interaction between the host and the parasite. In the system we studied, there are 3 critical stages for the outcome of infection of the (intermediate) host, the copepod Macrocyclops albidus, with the cestode Schistocephalus solidus. During the establishment pha...

    journal_title:Parasitology

    pub_type: 杂志文章

    doi:10.1017/s0031182001001275

    authors: van der Veen IT,Kurtz J

    更新日期:2002-04-01 00:00:00

  • The effect of infection with Lyme disease spirochetes (Borrelia burgdorferi) on the phototaxis, activity, and questing height of the tick vector Ixodes scapularis.

    abstract::Little is known about the effects of infection with Borrelia burgdorferi, the bacterium that causes Lyme disease, on its tick vectors. The purpose of this study was to determine the behavioural and ecological effects of infection by the bacterium in nymphal and adult black-legged (Ixodes scapularis) ticks. We found th...

    journal_title:Parasitology

    pub_type: 杂志文章

    doi:10.1017/s0031182000066336

    authors: Lefcort H,Durden LA

    更新日期:1996-08-01 00:00:00

  • Blood schizontocidal activity of azithromycin and its combination with alpha/beta arteether against multi-drug resistant Plasmodium yoelii nigeriensis, a novel MDR parasite model for antimalarial screening.

    abstract::Many different drug-resistant lines of rodent malaria are available as screening models. It is obligatory to screen new compounds for antimalarial activity against a series of resistant lines in order to identify a compound with potential for the treatment of multi-drug resistant (MDR) malaria infections. Instead of u...

    journal_title:Parasitology

    pub_type: 杂志文章

    doi:10.1017/s003118200500778x

    authors: Tripathi R,Dhawan S,Dutta GP

    更新日期:2005-09-01 00:00:00

  • Babesia microti and Borrelia bissettii transmission by Ixodes spinipalpis ticks among prairie voles, Microtus ochrogaster, in Colorado.

    abstract::An endemic transmission cycle of Babesia microti was discovered in Colorado in the foothills of the Rocky Mountains. B. microti were found by PCR in 4 of 25 Ixodes spinipalpis tick pools tested (a 3.2 % minimum infection rate) and in 87% (13 of 15) of Microtus ochrogaster (the prairie vole) spleen and blood samples. U...

    journal_title:Parasitology

    pub_type: 杂志文章

    doi:

    authors: Burkot TR,Schneider BS,Pieniazek NJ,Happ CM,Rutherford JS,Slemenda SB,Hoffmeister E,Maupin GO,Zeidner NS

    更新日期:2000-12-01 00:00:00

  • Parasites as biological tags of fish stocks: a meta-analysis of their discriminatory power.

    abstract::The use of parasites as biological tags to discriminate among marine fish stocks has become a widely accepted method in fisheries management. Here, we first link this approach to its unstated ecological foundation, the decay in the similarity of the species composition of assemblages as a function of increasing distan...

    journal_title:Parasitology

    pub_type: 杂志文章,meta分析,评审

    doi:10.1017/S0031182013001534

    authors: Poulin R,Kamiya T

    更新日期:2015-01-01 00:00:00

  • Isolation and characterization of secretions from the plant-parasitic nematode Globodera pallida.

    abstract::Electrophoresis of secretions collected from Globodera pallida revealed a smeared region between 25 and 50 kDa, and a single band of < 20 kDa. The secretions were used to raise an antiserum (LW1). Immunoblotting of parasite homogenates with LW1 differentiated G. pallida from its sibling species G. rostochiensis and re...

    journal_title:Parasitology

    pub_type: 杂志文章

    doi:10.1017/s0031182097001443

    authors: Duncan LH,Robertson L,Robertson WM,Kusel JR

    更新日期:1997-10-01 00:00:00

  • Changes in the somatic musculature of the 4th-stage larvae of Ascaris suum Goeze, 1782 (Nematoda: Ascaridoidea) developing in swine.

    abstract::Fourth-stage larvae of Ascaris suum, recovered from piglets at 11-22 days post-infection (p.i.), were examined by light microscopy for changes in the somatic musculature. During this time the estimated total number of muscle cells in the body increases from approximately 600 to 21 000 cells. This non-eutelic developme...

    journal_title:Parasitology

    pub_type: 杂志文章

    doi:10.1017/s003118200005441x

    authors: O'Grady RT

    更新日期:1984-02-01 00:00:00

  • Clustering of filarial infection in an age-graded study: genetic, household and environmental influences.

    abstract::A statistical method that analyses correlation structures in families to delineate the contribution of genetic, household and environmental factors on clustering of infection, has been applied to data collected in an area endemic for brugian filariasis in South Sulawesi, Indonesia. Infection was assessed both by micro...

    journal_title:Parasitology

    pub_type: 杂志文章

    doi:10.1017/s0031182003004487

    authors: Wahyuni S,Houwing-Duistermaat JJ,Syafruddin,Supali T,Yazdanbakhsh M,Sartono E

    更新日期:2004-03-01 00:00:00

  • High polymorphism in Plasmodium vivax merozoite surface protein-5 (MSP5).

    abstract::A key issue relating to developing multi-component anti-malarial vaccines, lies in studying Plasmodium vivax surface proteins' genetic variation. The present work was aimed at amplifying, cloning and sequencing the gene encoding P. vivax merozoite surface protein 5 (PvMSP5) in samples obtained from infected patients f...

    journal_title:Parasitology

    pub_type: 杂志文章

    doi:10.1017/S0031182006001168

    authors: Gomez A,Suarez CF,Martinez P,Saravia C,Patarroyo MA

    更新日期:2006-12-01 00:00:00

  • Malarial parasites and antioxidant nutrients.

    abstract::Susceptibility to oxidative stress is a well-established feature of the malarial parasite. Pharmacologists have taken advantage of this property to design highly effective pro-oxidant antimalarial drugs. Less well appreciated is the fact that nutritional manipulation of host oxidative stress status by dietary means ca...

    journal_title:Parasitology

    pub_type: 杂志文章,评审

    doi:10.1017/s0031182000075533

    authors: Levander OA,Ager AL Jr

    更新日期:1993-01-01 00:00:00

  • Integration and expression of murine retrovirus-related sequences in schistosomes.

    abstract::Antibodies against the retrovirus envelope glycoprotein (gp70) of mouse xenotropic retrovirus, BALB virus 2 (Bv2) reacted with the adult worms of Schistosoma japonicum and S. mansoni. This reaction was completely inhibited after adsorption of the antibodies with virions of retrovirus. The reactive schistosome antigen ...

    journal_title:Parasitology

    pub_type: 杂志文章

    doi:10.1017/s0031182000060996

    authors: Tanaka M,Iwamura Y,Amanuma H,Irie Y,Watanabe M,Watanabe T,Uchiyama Y,Yasuraoka K

    更新日期:1989-08-01 00:00:00

  • Molecular identification of Taenia spp. in the Eurasian lynx (Lynx lynx) from Finland.

    abstract::Cestodes of the genus Taenia are parasites of mammals, with mainly carnivores as definitive and herbivores as intermediate hosts. Various medium-sized cats, Lynx spp., are involved in the life cycles of several species of Taenia. The aim of the present study was to identify Taenia tapeworms in the Eurasian lynx (Lynx ...

    journal_title:Parasitology

    pub_type: 杂志文章

    doi:10.1017/S0031182012002120

    authors: Lavikainen A,Haukisalmi V,Deksne G,Holmala K,Lejeune M,Isomursu M,Jokelainen P,Näreaho A,Laakkonen J,Hoberg EP,Sukura A

    更新日期:2013-04-01 00:00:00

  • Impact of chemical structure of flavanol monomers and condensed tannins on in vitro anthelmintic activity against bovine nematodes.

    abstract::Plants containing condensed tannins (CT) may have potential to control gastrointestinal nematodes (GIN) of cattle. The aim was to investigate the anthelmintic activities of four flavan-3-ols, two galloyl derivatives and 14 purified CT fractions, and to define which structural features of CT determine the anti-parasiti...

    journal_title:Parasitology

    pub_type: 杂志文章

    doi:10.1017/S0031182015001912

    authors: Desrues O,Fryganas C,Ropiak HM,Mueller-Harvey I,Enemark HL,Thamsborg SM

    更新日期:2016-04-01 00:00:00

  • Nitric oxide interaction with IL-10, MIP-1alpha, MCP-1 and RANTES over the in vitro granuloma formation against different Schistosoma mansoni antigenic preparations on human schistosomiasis.

    abstract::Nitric oxide (NO) produced by cytokine-activated macrophages is reported to be cytotoxic against the helminth Schistosoma mansoni, although this is a controversial issue. Previous work in our laboratory identified a fraction of S. mansoni soluble adult worm antigenic preparation (SWAP), named PIII, able to elicit sign...

    journal_title:Parasitology

    pub_type: 杂志文章

    doi:10.1017/s0031182099005636

    authors: Oliveira DM,Silva-Teixeira DN,Gustavson S,Oliveira SM,Goes AM

    更新日期:2000-04-01 00:00:00

  • Immune modulation by a high molecular weight fraction from the rat tapeworm Hymenolepis diminuta.

    abstract::The host-parasite relationship is exquisitely specific. In exploiting the host niche, a variety of helminth parasites have been shown to directly manipulate their hosts' immune responses. We assessed the ability of a whole-worm extract of Hymenolepis diminuta to modulate immune cell activation. Immune cells isolated f...

    journal_title:Parasitology

    pub_type: 杂志文章

    doi:10.1017/s0031182004006985

    authors: Wang A,McKay DM

    更新日期:2005-05-01 00:00:00

  • Development of a strategy for the identification of surface proteins in the pathogenic microsporidian Nosema bombycis.

    abstract::Parasite-host interactions mediated by cell surface proteins have been implicated as a critical step in infections caused by the microsporidian Nosema bombycis. Such cell surface proteins are considered as promising diagnostic markers and targets for drug development. However, little research has specifically addresse...

    journal_title:Parasitology

    pub_type: 杂志文章

    doi:10.1017/S0031182015000190

    authors: Zhao W,Hao Y,Wang L,Zhou Z,Li Z

    更新日期:2015-06-01 00:00:00