Vaccines for amoebiasis: barriers and opportunities.

abstract：:A dipstick dot ELISA for detection of Taenia-specific coproantigens was developed. The test was based on a sandwich ELISA using antibodies raised against adult Taenia solium. Antibodies were absorbed to nitrocellulose paper previously adhered to acetate plastic to form dipsticks. Once blocked with 5% skimmed milk and ...

journal_title：Parasitology

authors： Allan JC,Mencos F,Garcia-Noval J,Sarti E,Flisser A,Wang Y,Liu D,Craig PS

更新日期：1993-07-01 00:00:00

abstract：:Susceptibility to oxidative stress is a well-established feature of the malarial parasite. Pharmacologists have taken advantage of this property to design highly effective pro-oxidant antimalarial drugs. Less well appreciated is the fact that nutritional manipulation of host oxidative stress status by dietary means ca...

journal_title：Parasitology

authors： Levander OA,Ager AL Jr

更新日期：1993-01-01 00:00:00

abstract：:Schistosomiasis is a health problem in Brazil and the role of rodents in maintaining the schistosome life-cycle requires further clarification. The influence of Schistosoma mansoni on a population of Nectomys squamipes was studied by capture-recapture (1st phase, from June 1991 to November 1995) and removal (2nd phase...

journal_title：Parasitology

authors： D'Andrea PS,Maroja LS,Gentile R,Cerqueira R,Maldonado Júnior A,Rey L

更新日期：2000-06-01 00:00:00

abstract：:Ornithodoros moubata ticks were fed on blood infected with Babesia equi. However, the parasites were quickly cleared as evidenced by the disappearance of B. equi-specific ribosomal RNA from the ticks. We hypothesized that if the Babesia parasite can escape midgut-associated barriers a non-vector tick can become infect...

journal_title：Parasitology

authors： Battsetseg B,Matsuo T,Xuan X,Boldbaatar D,Chee SH,Umemiya R,Sakaguchi T,Hatta T,Zhou J,Verdida AR,Taylor D,Fujisaki K

更新日期：2007-01-01 00:00:00

abstract：:An endemic transmission cycle of Babesia microti was discovered in Colorado in the foothills of the Rocky Mountains. B. microti were found by PCR in 4 of 25 Ixodes spinipalpis tick pools tested (a 3.2 % minimum infection rate) and in 87% (13 of 15) of Microtus ochrogaster (the prairie vole) spleen and blood samples. U...

journal_title：Parasitology

authors： Burkot TR,Schneider BS,Pieniazek NJ,Happ CM,Rutherford JS,Slemenda SB,Hoffmeister E,Maupin GO,Zeidner NS

更新日期：2000-12-01 00:00:00

abstract：:The localization and distribution of neuropeptides in the nervous system of the liver fluke, Fasciola hepatica at different stages in the development of the adult fluke have been determined by an indirect immunofluorescence technique, using antisera to 19 vertebrate peptides and the invertebrate neuropeptide, FMRFamid...

journal_title：Parasitology

authors： Magee RM,Fairweather I,Johnston CF,Halton DW,Shaw C

更新日期：1989-04-01 00:00:00

abstract：:An electron microscopical study was made on the development of Eimeria dispersa in the small intestine of the domestic turkey. Turkey poults, 10-14 days of age, were inoculated with oocysts and pieces of intestinal tissue were fixed at intervals between 3.5 and 114 h after inoculation. Sporozoites were occasionally se...

journal_title：Parasitology

authors： Millard BJ,Lawn AM

更新日期：1982-02-01 00:00:00

abstract：:A rapid, visually read, dot-ELISA developed for the detection and differentiation of trypanosome species in tsetse flies (Glossina spp.), was field tested alongside the standard fly dissection method on a range in south eastern Kenya. Of 104 G. pallidipes dissected, 2 were found to be infected with trypanosomes in the...

journal_title：Parasitology

authors： Bosompem KM,Masake RA,Assoku RK,Opiyo EA,Nantulya VM

更新日期：1996-02-01 00:00:00

abstract：:Development and forward migration of Leishmania parasites in the sandfly gut is accompanied by morphological transformation to highly motile, non-dividing 'metacyclic' forms. Previous studies in vitro have demonstrated that this metacyclogenesis is associated with developmentally regulated changes in expression of two...

journal_title：Parasitology

authors： Davies CR,Cooper AM,Peacock C,Lane RP,Blackwell JM

更新日期：1990-12-01 00:00:00

abstract：:cDNA-AFLP (cDNA-Amplified Fragment Length Polymorphism)-based strategy has been used to identify levamisole (LEV) resistance markers in the nematode Haemonchus contortus. Transcript profiles of adult nematodes from two LEV-resistant and two susceptible isolates were compared. Among the 17 280 transcript-derived fragme...

journal_title：Parasitology

authors： Neveu C,Charvet C,Fauvin A,Cortet J,Castagnone-Sereno P,Cabaret J

更新日期：2007-01-01 00:00:00

abstract：:Strongyloides ratti is a parasitic nematode of rats. The host immune response against S. ratti affects the development of its free-living generation, favouring the development of free-living adult males and females at the expense of directly developing, infective 3rd-stage larvae. However, how the host immune response...

journal_title：Parasitology

authors： Crook M,Viney ME

更新日期：2005-09-01 00:00:00

abstract：:Laboratory experiments indicated that the active life-span of the cercariae of Cryptocotyle lingua was temperature-dependent. An increase in water temperature and population age both correlated with a tendency for the organisms to become decaudate. The larvae were strongly photoresponsive to lateral light but with tim...

journal_title：Parasitology

authors： Rea JG,Irwin SW

更新日期：1992-08-01 00:00:00

abstract：:Diagnostic PCR primers for Trichinella were constructed. Twelve pairs of primers were designed based on the sequences of random amplified polymorphic DNA, and 4 pairs of primers were designed based on the reported sequences of complementary DNA encoding excretory-secretory glycoproteins. With these primers, 31 samples...

journal_title：Parasitology

authors： Wu Z,Nagano I,Takahashi Y

更新日期：1998-08-01 00:00:00

abstract：:An hypothesis is presented to explain the red cell lysis which accompanies an acute malarial infection, as well as the mode of action of certain schizonticidal drugs in the quinoline and acridine series. Quinine and a number of other antimalarial drugs have been found to counteract the inhibition by protein of fatty a...

journal_title：Parasitology

authors： Laser H,Kemp P,Miller N,Lander D,Klein R

更新日期：1975-10-01 00:00:00

abstract：:During the course of Schistosoma mansoni murine infection there is a dramatic increase of some immunoglobulins and S. mansoni-specific antibodies. The most substantial response is initiated after 40 days of infection and results in a prolonged increase of total IgG1, IgM and IgA. The maximum increase is respectively 2...

journal_title：Parasitology

authors： Bout D,Rousseaux R,Carlier Y,Capron A

更新日期：1980-04-01 00:00:00

abstract：:Voltage-gated calcium (Ca2+) channels contribute to impulse propagation in excitable cells and also regulate intracellular levels of Ca2+. High voltage-activated (HVA) Ca2+ channels are heteromultimeric membrane proteins. The pore-forming, voltage-sensing subunit is the alpha1 subunit. We have cloned 3 HVA Ca2+ channe...

journal_title：Parasitology

authors： Kohn AB,Lea J,Roberts-Misterly JM,Anderson PA,Greenberg RM

更新日期：2001-11-01 00:00:00

abstract：:Toxoplasma gondii and Sarcocystis neurona are protozoan parasites with terrestrial definitive hosts, and both pathogens can cause fatal disease in a wide range of marine animals. Close monitoring of threatened southern sea otters (Enhydra lutris nereis) in California allowed for the diagnosis of dual transplacental tr...

journal_title：Parasitology

authors： Shapiro K,Miller MA,Packham AE,Aguilar B,Conrad PA,Vanwormer E,Murray MJ

更新日期：2016-03-01 00:00:00

abstract：:Embryonic stages of various Onchocerca species have been used to stimulate resistance in CBA mice to challenge injections with the microfilariae of Onchocerca lienalis. Comparable levels of resistance to challenge (29-37% reductions) were conferred by living, freeze-killed, or sonicated organisms administered with Fre...

journal_title：Parasitology

authors： Carlow CK,Bianco AE

更新日期：1987-06-01 00:00:00

abstract：:Protozoan parasites of the genus Cryptosporidium infect all vertebrate groups and display some host specificity in their infections. It is therefore possible to assume that Cryptosporidium parasites evolved intimately aside with vertebrate lineages. Here we propose a scenario of Cryptosporidium-Vertebrata coevolution ...

journal_title：Parasitology

authors： Garcia-R JC,Hayman DT

更新日期：2016-11-01 00:00:00

abstract：:BALB/c mice were characterized as more resistant to infection with Heligmosomoides polygyrus (Nematoda) than C57BL/6 mice based on lower establishment and survival during a primary infection and stronger protection induced by an immunizing regime. It was hypothesized, therefore, that C57BL/6 mice would be more heavily...

journal_title：Parasitology

authors： Scott ME

更新日期：1991-12-01 00:00:00

abstract：:Two cDNAs encoding cysteine proteinases were isolated from a cDNA library constructed from feeding females of Heterodera glycines. The library was screened with a cysteine proteinase gene fragment originally amplified from cDNA of H. glycines. Database searches predict that 1 cDNA (hgcp-I) encodes a cathepsin L-like p...

journal_title：Parasitology

authors： Urwin PE,Lilley CJ,McPherson MJ,Atkinson HJ

更新日期：1997-06-01 00:00:00

abstract：:Hymenolepis microstoma from secondary infections in mice were found to grow initially more slowly than H. microstoma from primary infections. Eventually a similar rate of growth was attained by both kinds of worm. After transplantation, young worms (less than or equal to 4 days old) grew more slowly in previously infe...

journal_title：Parasitology

authors： Howard RJ

更新日期：1977-10-01 00:00:00

abstract：:Infections with Haemonchus contortus are a major constraint on ruminant health world-wide. Young lambs are very sensitive to Haemonchus infection. Older lambs and sheep acquire immunity after a continuous or seasonal exposure to the parasite. The mechanisms underlying immunity are still not completely understood. Anti...

journal_title：Parasitology

authors： Schallig HD

更新日期：2000-01-01 00:00:00

abstract：:In the context of a broader program dealing with the symbiotic associations of apple snails, we sampled three species that coexist in Lake Regatas (Palermo, Buenos Aires, Argentina). The population of Asolene platae, (but not those of Pomacea canaliculata and Pomacea scalaris) showed trematode larvae (echinocercariae ...

journal_title：Parasitology

authors： Dellagnola FA,Montes MM,Martorelli SR,Vega IA

更新日期：2019-06-01 00:00:00

abstract：:The genetic basis of virulence in a line (YM) of Plasmodium yoelii yoelii was investigated in a cross with a mild line (A/C). The blood forms of the virulent line developed extensively in mature erythrocytes of mice, causing death of the host within 7 days; infections with the mild line were normally restricted to ret...

journal_title：Parasitology

authors： Walliker D,Sanderson A,Yoeli M,Hargreaves BJ

更新日期：1976-04-01 00:00:00

abstract：:Human strongyloidiasis is a serious disease mostly attributable to Strongyloides stercoralis and to a lesser extent Strongyloides fuelleborni, a parasite mainly of non-human primates. The role of animals as reservoirs of human-infecting Strongyloides is ill-defined, and whether dogs are a source of human infection is ...

journal_title：Parasitology

authors： Barratt JLN,Sapp SGH

更新日期：2020-09-01 00:00:00

abstract：:This paper reviews naturally occurring and synthetic compounds that either enhance immune defences or lower both natural and acquired immunity. Immunomodulatory agents used both for laboratory study and clinically for the management of immunologically based diseases are considered. ...

journal_title：Parasitology

authors： Nüssler AK,Thomson AW

更新日期：1992-01-01 00:00:00

abstract：:Philasterides dicentrarchi is a histophagous ciliate causing systemic scuticociliatosis in cultured turbot. This study demonstrates that turbot which survive this disease have serum antibodies that recognize ciliary antigens of this ciliate in ELISA and immobilize/agglutinate the ciliate in vitro. Mouse sera raised ag...

journal_title：Parasitology

authors： Iglesias R,Paramá A,Alvarez MF,Leiro J,Ubeira FM,Sanmartín ML

更新日期：2003-02-01 00:00:00

abstract：:Previous studies of mating interactions between schistosome species from different evolutionary lineages in mice showed that mating is not random: heterospecific pairs form but, given the choice, the preference is for homospecific partners. Mating competition and change of mate were also demonstrated. Schistosoma mans...

journal_title：Parasitology

authors： Cosgrove CL,Southgate VR

更新日期：2002-09-01 00:00:00

abstract：:In an interconnected world, the international pet trade on wild animals is becoming increasingly important. As a consequence, non-native parasite species are introduced, which affect the health of wildlife and contribute to the loss of biodiversity. Because the investigation of parasite diversity within vulnerable hos...

journal_title：Parasitology

authors： Héritier L,Verneau O,Breuil G,Meistertzheim AL

更新日期：2017-04-01 00:00:00