Babesia parasites develop and are transmitted by the non-vector soft tick Ornithodoros moubata (Acari: Argasidae).

Abstract:

:Ornithodoros moubata ticks were fed on blood infected with Babesia equi. However, the parasites were quickly cleared as evidenced by the disappearance of B. equi-specific ribosomal RNA from the ticks. We hypothesized that if the Babesia parasite can escape midgut-associated barriers a non-vector tick can become infected with Babesia. To test this hypothesis, B. equi parasite-infected blood from in vitro culture was injected into the haemocoel of ticks. B. equi-specific rRNA was surprisingly detected 45 days after injection even in the eggs. Babesia-free dogs were infested with O. moubata ticks that were infected by inoculation with B. gibsoni-infected red blood cells. Parasitaemia and antibody production against Bg-TRAP of B. gibsoni increased gradually. These results indicate that O. moubata may be a useful vector model for Babesia parasites and also a very important tool for studies on tick immunity against Babesia parasites and tick-Babesia interactions.

journal_name

Parasitology

journal_title

Parasitology

authors

Battsetseg B,Matsuo T,Xuan X,Boldbaatar D,Chee SH,Umemiya R,Sakaguchi T,Hatta T,Zhou J,Verdida AR,Taylor D,Fujisaki K

doi

10.1017/S0031182006000916

subject

Has Abstract

pub_date

2007-01-01 00:00:00

pages

1-8

issue

Pt 1

eissn

0031-1820

issn

1469-8161

pii

S0031182006000916

journal_volume

134

pub_type

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