Abstract:
:Hymenolepis microstoma from secondary infections in mice were found to grow initially more slowly than H. microstoma from primary infections. Eventually a similar rate of growth was attained by both kinds of worm. After transplantation, young worms (less than or equal to 4 days old) grew more slowly in previously infected than in naive mice. In contrast, 10-day-old worms grew equally well in naive or resistant mice. The administration of cortisone to mice during a secondary infection of H. microstoma inhibited the stunting of growth in young worms which were able to grow as well as those in a primary infection. The effects of the cortisone persisted for less than 4 days. Worms in a secondary infection given 4 days after cortisone treatment were stunted in growth. These experiments suggest that the susceptibility of the worms to the resistance of the mouse applies to the first 4 days within the host. The loss or reduction of this susceptibility might be associated with the worm's entry into the bile duct which occurs 3--4 days after infection.
journal_name
Parasitologyjournal_title
Parasitologyauthors
Howard RJdoi
10.1017/s0031182000062387subject
Has Abstractpub_date
1977-10-01 00:00:00pages
241-9issue
2eissn
0031-1820issn
1469-8161journal_volume
75pub_type
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