Structure of three high voltage-activated calcium channel alpha1 subunits from Schistosoma mansoni.

abstract：:Schistosoma mansoni depends for its survival on glycolysis. Two glycolytic enzymes, glyceraldehyde-3P-dehydrogenase and triose-phosphate dehydrogenase, found in both the adult and schistosomular tegument, have been reported to confer partial protection against cercarial infection. This paper describes the immunogenic ...

journal_title：Parasitology

authors： Mansour JM,McCrossan MV,Bickle QD,Mansour TE

更新日期：2000-05-01 00:00:00

abstract：:The interactions in vivo between Plasmodium berghei sporozoites and Kupffer cells in rat livers were studied by transmission electron microscopy. By 10 and 15 min after inoculation, sporozoites were both free in the liver sinusoids and inside endocytotic vacuoles of the Kupffer cells. The latter cells were very active...

journal_title：Parasitology

authors： Meis JF,Verhave JP,Jap PH,Meuwissen JH

更新日期：1983-04-01 00:00:00

abstract：:We cloned and expressed Echinostoma caproni HSP70 in Escherichia coli. This molecule presents an open reading frame (ORF) of 655 amino acids, and a theoretical molecular weight of 71 kDa. E. caproni HSP70 protein showed a high homology to other helminth molecules, major differences being located in the C-terminal regi...

journal_title：Parasitology

authors： Higón M,Monteagudo C,Fried B,Esteban JG,Toledo R,Marcilla A

更新日期：2008-10-01 00:00:00

abstract：:Expression of metalloprotease activities during metacyclogenesis of a series of strains and clones of Trypanosoma cruzi was investigated using SDS-polyacrylamide gel electrophoresis with a range of different co-polymerized proteolytic substrates. A complex pattern of metalloprotease expression, with considerable quant...

journal_title：Parasitology

authors： Lowndes CM,Bonaldo MC,Thomaz N,Goldenberg S

更新日期：1996-04-01 00:00:00

abstract：:Cats were repeatedly inoculated with infective larvae of Brugia pahangi. On parasitological grounds they could be divided into 5 groups. Group I--most cats (some 70%) became microfilaraemic (mf+) and retained high levels of microfilariae (mf) in their blood for over 2 years. In some Group I cats mf counts stabilized a...

journal_title：Parasitology

authors： Denham DA,Medeiros F,Baldwin C,Kumar H,Midwinter IC,Birch DW,Smail A

更新日期：1992-06-01 00:00:00

abstract：:Host location by parasites can be achieved by either active or passive mechanisms. In spite of their significance, the efficacy of these methods has been little researched. High fecundity in parasites is discussed in terms of the role it plays in dispersal and transmission. Some concepts developed by mainstream behavi...

journal_title：Parasitology

authors： Rea JG,Irwin SW

更新日期：1994-01-01 00:00:00

abstract：:The relative importance of temporal and spatial effects was assessed in helminth communities of bank voles (Myodes glareolus) in 3 woodland sites in N.E. Poland in the late summers of 1999 and 2002. Among common species the rank order of sites in relation to prevalence and abundance of infection was maintained between...

journal_title：Parasitology

authors： Behnke JM,Bajer A,Harris PD,Newington L,Pidgeon E,Rowlands G,Sheriff C,Kuliś-Malkowska K,Siński E,Gilbert FS,Barnard CJ

更新日期：2008-07-01 00:00:00

abstract：:Depending on the extent of evolutionary divergence among parent taxa, hybrids may suffer from a breakdown of co-adapted genes or may conversely exhibit vigour due to the heterosis effect, which confers advantages to increased genetic diversity. That last mechanism could explain the success of hybrids when hybridizatio...

journal_title：Parasitology

authors： Planade B,Lena JP,Li H,Plenet S,Guegan JF,Thomas F,Hurtrez-Bousses S,Renaud F,Joly P

更新日期：2009-08-01 00:00:00

abstract：:Species composition of wild reservoir hosts can influence the transmission and maintenance of multi-host vector borne pathogens. The 'pace of life' hypothesis proposes that the life history strategy of reservoir hosts can influence pathogen transmission of vector borne generalist pathogens. We use empirical data to pa...

journal_title：Parasitology

authors： Erazo D,Cordovez J,Cabrera C,Calzada JE,Saldaña A,Gottdenker NL

更新日期：2017-12-01 00:00:00

abstract：:The phenotypic activity of two 5-nitroindazolinones, i.e. 2-benzyl-1-propyl (22) and 2-benzyl-1-butyl (24) derivatives, previously proposed as anti-Trypanosoma cruzi prototypes, was presently assayed on bloodstream trypomastigotes (BT) of the moderately drug-resistant Y strain. Further exploration of putative targets ...

journal_title：Parasitology

authors： Fonseca-Berzal C,DA Silva CF,Menna-Barreto RF,Batista MM,Escario JA,Arán VJ,Gómez-Barrio A,Soeiro Mde N

更新日期：2016-09-01 00:00:00

abstract：:In this article I begin with a few current ideas on some physiological factors that influence mating choice in insects. Emphasis is placed on those proteins produced by the male reproductive accessory glands which increase female fecundity and reduce her receptivity to subsequent males. Strategies used by late-arrivin...

journal_title：Parasitology

authors： Kaufman WR

更新日期：2004-01-01 00:00:00

abstract：:Giardia lamblia localize and multiply in the small intestine and may cause acute or chronic diarrhoea with malabsorption of fat, protein and other nutrients. Abnormal pancreatic function has been documented in giardiasis and trophozoites directly inhibit pancreatic lipase activity in vitro. The aim of this study was t...

journal_title：Parasitology

authors： Seow F,Katelaris P,Ngu M

更新日期：1993-04-01 00:00:00

abstract：:By means of conventional light microscopical and counting procedures, estimations have been made of the average number and size of ovarian balls from unfertilized and fertilized female Moniliformis dubius. The observations were made on worms recovered from experimental primary infections lasting 1, 2, 3, 4, 5, 8, 11, ...

journal_title：Parasitology

authors： Crompton DW,Arnold S

更新日期：1976-08-01 00:00:00

abstract：:Many marine fisheries in South American Atlantic coasts (SAAC) are threatened by overfishing and under serious risk of collapsing. The SAAC comprises a diversity of environments, possesses a complex oceanography and harbours a vast biodiversity that provide an enormous potential for using parasites as biological tags ...

journal_title：Parasitology

authors： Cantatore DM,Timi JT

更新日期：2015-01-01 00:00:00

abstract：:Neurocysticercosis (NCC) is the most common parasitic disease of the central nervous system (CNS) caused by the larval form of the tapeworm Taenia solium. NCC has a long asymptomatic period with little or no inflammation, and the sequential progression to symptomatic NCC depends upon the intense inflammation associate...

journal_title：Parasitology

authors： Alvarez JI,Mishra BB,Gundra UM,Mishra PK,Teale JM

更新日期：2010-03-01 00:00:00

abstract：:Angiostrongylus cantonensis is a metastrongyloid nematode found widely in the Asia-Pacific region, and the aetiological agent of angiostrongyliasis; a disease characterized by eosinophilic meningitis. Rattus rats are definitive hosts of A. cantonensis, while intermediate hosts include terrestrial and aquatic molluscs....

journal_title：Parasitology

authors： Barratt J,Chan D,Sandaradura I,Malik R,Spielman D,Lee R,Marriott D,Harkness J,Ellis J,Stark D

更新日期：2016-08-01 00:00:00

abstract：:Pinewood nematode, Bursaphelenchus xylophilus, a pine parasitic nematode, poses a serious threat to its host pine forests globally. When dispersal-stage larvae 4 (dauer, DL4) of B. xylophilus enters the new pine, it moults into propagative adult (dauer recovery) and reproduces quickly to kill the host pine. Here, we f...

journal_title：Parasitology

authors： Zhang W,Li Y,Pan L,Wang X,Feng Y,Zhang X

更新日期：2020-01-01 00:00:00

abstract：:Two experiments were carried out in which calves reared parasite-free were infected with a single dose of 3rd-stage larvae of Cooperia oncophora. In the first experiment the calves received 20 000 or 200 000 infective larvae and they were autopsied 28 or 56 days after the infection. In the second experiment the doses ...

journal_title：Parasitology

authors： Borgsteede FH,Hendriks J

更新日期：1979-06-01 00:00:00

abstract：:This study quantifies the rate and intensity of re-infection with human hookworm and Schistosoma mansoni infection 12 months following successful treatment, and investigates the influence of socio-economic, geographical and environmental factors. A longitudinal study of 642 individuals aged over 5 years was conducted ...

journal_title：Parasitology

authors： Cundill B,Alexander N,Bethony JM,Diemert D,Pullan RL,Brooker S

更新日期：2011-09-01 00:00:00

abstract：:There has been an enormous growth in the development of biotechnological applications, where advances in the techniques of microelectronic fabrication and the technologies of miniaturization and integration in semiconductor industries are being applied to the production of Laboratory-on-a-Chip devices. The aim of this...

journal_title：Parasitology

authors： Talary MS,Burt JP,Pethig R

更新日期：1998-01-01 00:00:00

abstract：:The current trend of antimony (Sb) unresponsiveness in the Indian subcontinent is a major impediment to effective chemotherapy of visceral leishmaniasis (VL). Although contributory mechanisms studied in laboratory-raised Sb-R parasites include an up-regulation of drug efflux pumps and increased thiols, their role in c...

journal_title：Parasitology

authors： Mandal G,Wyllie S,Singh N,Sundar S,Fairlamb AH,Chatterjee M

更新日期：2007-11-01 00:00:00

abstract：:Eukaryotic 5S rRNA, synthesized by RNA polymerase III (Pol III), is an essential component of the large ribosomal subunit. Most organisms contain hundreds of 5S rRNA genes organized into tandem arrays. However, the genome of the protozoan parasite Leishmania major contains only 11 copies of the 5S rRNA gene, which are...

journal_title：Parasitology

authors： Moreno-Campos R,Florencio-Martínez LE,Nepomuceno-Mejía T,Rojas-Sánchez S,Vélez-Ramírez DE,Padilla-Mejía NE,Figueroa-Angulo E,Manning-Cela R,Martínez-Calvillo S

更新日期：2016-12-01 00:00:00

abstract：:Many zoonotic disease agents are transmitted between hosts by arthropod vectors, including fleas, but few empirical studies of host-vector-microparasite dynamics have investigated the relative importance of hosts and vectors. This study investigates the dynamics of 4 closely related Bartonella species and their flea v...

journal_title：Parasitology

authors： Telfer S,Begon M,Bennett M,Bown KJ,Burthe S,Lambin X,Telford G,Birtles R

更新日期：2007-03-01 00:00:00

abstract：:Epidemiological rate parameters of host generalist parasites are difficult to estimate, especially in cases where variation in parasite performance can be attributed to host species. Such cases are likely common for generalist parasites of sympatric grazing mammals. In this study, we combined data from experimental ex...

journal_title：Parasitology

authors： Beck MA,Goater CP,Colwell DD

更新日期：2015-09-01 00:00:00

abstract：:The World Health Organization announced in November 2014 at the fourth international meeting on 'the control of neglected zoonotic diseases - from advocacy to action', that intervention tools for eliminating Taenia solium taeniosis/cysticercosis (TSTC) are in place. The aim of this work was to elucidate theoretical ou...

journal_title：Parasitology

authors： Johansen MV,Trevisan C,Gabriël S,Magnussen P,Braae UC

更新日期：2017-01-01 00:00:00

abstract：:Diagnostic PCR primers for Trichinella were constructed. Twelve pairs of primers were designed based on the sequences of random amplified polymorphic DNA, and 4 pairs of primers were designed based on the reported sequences of complementary DNA encoding excretory-secretory glycoproteins. With these primers, 31 samples...

journal_title：Parasitology

authors： Wu Z,Nagano I,Takahashi Y

更新日期：1998-08-01 00:00:00

abstract：:Understanding the origin of invasive parasites and ecological transmission barriers on the distribution of mosquito-borne pathogens is enriched by molecular phylogenetic approaches now that large databases are becoming available. Here we assess the biogeographical relationships among haemosporidian blood parasites and...

journal_title：Parasitology

authors： Baillie SM,Brunton DH

更新日期：2011-12-01 00:00:00

abstract：:Parasite-host interactions mediated by cell surface proteins have been implicated as a critical step in infections caused by the microsporidian Nosema bombycis. Such cell surface proteins are considered as promising diagnostic markers and targets for drug development. However, little research has specifically addresse...

journal_title：Parasitology

authors： Zhao W,Hao Y,Wang L,Zhou Z,Li Z

更新日期：2015-06-01 00:00:00

abstract：:To recognize the stage conversion of Toxoplasma gondii between tachyzoite and bradyzoite in live host cells, a transgenic T. gondii line, which expressed stage-specific red and green fluorescence, was constructed. T. gondii PLK strain tachyzoites were stably transformed with genes encoding red fluorescent protein (DsR...

journal_title：Parasitology

authors： Unno A,Suzuki K,Batanova T,Cha SY,Jang HK,Kitoh K,Takashima Y

更新日期：2009-05-01 00:00:00

abstract：:This study describes morphological changes during capsule formation of Trichinella spiralis with emphasis on nuclei within the capsule. The nuclei of the pre-existing muscle cell may become hypertrophied or degrade soon after the entrance of newborn larvae. Cytoplasm associated with these hypertrophied nuclei was baso...

journal_title：Parasitology

authors： Matsuo A,Wu Z,Nagano I,Takahashi Y

更新日期：2000-08-01 00:00:00