Biological approaches to characterize the mode of action of two 5-nitroindazolinone prototypes on Trypanosoma cruzi bloodstream trypomastigotes.

abstract：:The population of malaria-causing parasites is characterized by great genetic diversity. Knowledge of the polymorphism generation mechanism is a central issue for developing effective vaccines against malaria and understanding the parasite population structure. Plasmodium vivax genetic diversity has been explained in ...

journal_title：Parasitology

authors： Martinez P,Suarez CF,Cardenas PP,Patarroyo MA

更新日期：2004-04-01 00:00:00

abstract：:Neospora caninum infection is a significant cause of abortion in cattle. We investigated the tissue distribution of N. caninum in aborted bovine fetuses and dam blood samples by a nested PCR assay, and compared the nested PCR with ELISA in the diagnosis of N. caninum infection. In total, 26 aborted fetuses and 813 blo...

journal_title：Parasitology

authors： Yao L,Yang N,Liu Q,Wang M,Zhang W,Qian WF,Hu YF,Ding J

更新日期：2009-09-01 00:00:00

abstract：:Polychromophilus murinus, a malaria parasite of Chiroptera is reported from Myotis daubentoni in England. The vector was suspected to be the ectoparasitic Nycteribiid fly, Nycteribia kolenatii. N. kolenatii collected from wild-caught M. daubentoni were found to have oocysts on the midgut and sporozoites in the salivar...

journal_title：Parasitology

authors： Gardner RA,Molyneux DH

更新日期：1988-06-01 00:00:00

abstract：:Sex ratio theory posits that the adaptive proportion of male to female gametocytes of a malaria parasite within the vertebrate host depends on the degree of inbreeding within the vector. Gametocyte sex ratio could be phenotypically flexible, being altered based on the infection's clonal diversity, and thus likely inbr...

journal_title：Parasitology

authors： Osgood SM,Schall JJ

更新日期：2004-01-01 00:00:00

abstract：:A study carried out on a sheep farm examined whether Toxoplasma gondii foetal infection and associated abortion occur in successive lambings. We identified 29 ewes that gave birth to lambs on at least 2 successive years over our study period, 2000-2003. Tissue samples from the progeny of these ewes were analysed by PC...

journal_title：Parasitology

authors： Morley EK,Williams RH,Hughes JM,Thomasson D,Terry RS,Duncanson P,Smith JE,Hide G

更新日期：2008-02-01 00:00:00

abstract：:This study evaluated the effectiveness of low doses of benznidazole (BNZ) on continuous administration (BNZc), combined with allopurinol (ALO), in C57BL/6J and C3H/HeN mice infected with Trypanosoma cruzi Nicaragua strain and T. cruzi Sylvio-X10/4 clone. TcN-C57BL/6J was also treated with intermittent doses of BNZ (BN...

journal_title：Parasitology

authors： Rial MS,Scalise ML,López Alarcón M,Esteva MI,Búa J,Benatar AF,Prado NG,Riarte AR,Fichera LE

更新日期：2019-03-01 00:00:00

abstract：:A molecular approach was used to genetically characterize 5 species (Aoruroides queenslandensis, Blattophila sphaerolaima, Cordonicola gibsoni, Desmicola ornata and Leidynemella fusiformis) belonging to the superfamily Thelastomatoidea (Nematoda: Oxyurida), a group of pinworms that parasitizes terrestrial arthropods. ...

journal_title：Parasitology

authors： Jex AR,Hu M,Rose HA,Schneider M,Cribb TH,Gasser RB

更新日期：2006-07-01 00:00:00

abstract：:We assessed the distribution of Trypanosoma cruzi Discrete Typing Units (DTUs) in domestic and peridomestic Triatoma infestans and Triatoma sordida specimens collected in a well-defined rural area in Pampa del Indio, northeastern Argentina. Microscopically-positive bugs were randomly selected with a multi-level sampli...

journal_title：Parasitology

authors： Maffey L,Cardinal MV,Ordóñez-Krasnowski PC,Lanati LA,Lauricella MA,Schijman AG,Gürtler RE

更新日期：2012-10-01 00:00:00

abstract：:Sequence comparisons have recently shown that the Schistosoma mansoni protein Sm32 is similar to asparaginyl endoproteinases, a novel family of cysteine proteinases, of which the legumains from legumes are the best characterized. By synthesizing and employing fluorogenic peptide substrates for the specific detection o...

journal_title：Parasitology

authors： Dalton JP,Hola-Jamriska L,Brindley PJ

更新日期：1995-12-01 00:00:00

abstract：:Immunological and structural changes in the thymus and pronephros of Cyprinus carpio infected with the blood fluke, Sanguinicola inermis for 30 days, and exposed to 0.5 mg NH4+/1 for 48 and 168 h were investigated. Ultrastructural observations revealed cell disruption and highly vacuolated cytoplasm in the thymus. Of ...

journal_title：Parasitology

authors： Schuwerack PM,Lewis JW,Hoole D,Morley NJ

更新日期：2001-03-01 00:00:00

abstract：:Two natural human interferon alpha preparations, (nHuIFN-alpha [Cantell]) and (nHuIFN-alpha [ISI]), were used for the oral treatment of cattle experimentally infected with Theileria parva parva. In the first experiment, 8 Friesian bulls were inoculated with a 1 in 10 dilution of a sporozoite stabilate of T.p. parva (M...

journal_title：Parasitology

authors： Young AS,Maritim AC,Kariuki DP,Stagg DA,Wafula JM,Mutugi JJ,Cummins JM,Richards AB,Burns C

更新日期：1990-10-01 00:00:00

abstract：:Receptors interacting with terminal sugars as ligands are involved in the binding of Leishmania donovani promastigotes to the macrophage surface and their subsequent internalization. Mannose and glucose are specifically involved in the binding process. Decreased binding occurs to macrophages already infected with L. d...

journal_title：Parasitology

authors： Dutta M,Bandyopadhyay R,Basu MK

更新日期：1994-08-01 00:00:00

abstract：:Blastocystis SSU-rDNA sequence data from 317 captive and free-living non-human primates (NHPs) representing 30 genera of apes, Old and New World (OW and NW) monkeys and prosimians were analysed to investigate subtype (ST) and allele distribution among hosts. Excluding 20 mixed ST infections, 27% of the sequences belon...

journal_title：Parasitology

authors： Alfellani MA,Jacob AS,Perea NO,Krecek RC,Taner-Mulla D,Verweij JJ,Levecke B,Tannich E,Clark CG,Stensvold CR

更新日期：2013-07-01 00:00:00

abstract：:The major transaminase in Heligmosomoides polygyrus, Panagrellus redivivus and rat liver was the 2-oxoglutarate-glutamate system, with relatively few amino acids acting as donors for the pyruvate-alanine and oxaloacetate-aspartate systems. The relative effectiveness of the different amino acid donors in the three tran...

journal_title：Parasitology

authors： Grantham BD,Barrett J

更新日期：1986-12-01 00:00:00

abstract：:Schistosomiasis is a health problem in Brazil and the role of rodents in maintaining the schistosome life-cycle requires further clarification. The influence of Schistosoma mansoni on a population of Nectomys squamipes was studied by capture-recapture (1st phase, from June 1991 to November 1995) and removal (2nd phase...

journal_title：Parasitology

authors： D'Andrea PS,Maroja LS,Gentile R,Cerqueira R,Maldonado Júnior A,Rey L

更新日期：2000-06-01 00:00:00

abstract：:Insecticide-treated nets (ITNs) are a major tool to control malaria. Over recent years increased ITN coverage has been associated with decreased malaria transmission. However, ITN 'misuse' has been increasingly reported and whether this emergent behaviour poses a threat to successful malaria control and elimination is...

journal_title：Parasitology

authors： Honjo K,Chaves LF,Satake A,Kaneko A,Minakawa N

更新日期：2013-04-01 00:00:00

abstract：:Pinewood nematode, Bursaphelenchus xylophilus, a pine parasitic nematode, poses a serious threat to its host pine forests globally. When dispersal-stage larvae 4 (dauer, DL4) of B. xylophilus enters the new pine, it moults into propagative adult (dauer recovery) and reproduces quickly to kill the host pine. Here, we f...

journal_title：Parasitology

authors： Zhang W,Li Y,Pan L,Wang X,Feng Y,Zhang X

更新日期：2020-01-01 00:00:00

abstract：:We estimate the incidence rate, serological conversion rate and basic case reproduction number (R0) of Leishmania infantum from a cohort study of 126 domestic dogs exposed to natural infection rates over 2 years on Marajó Island, Pará State, Brazil. The analysis includes new methods for (1) determining the number of s...

journal_title：Parasitology

authors： Quinnell RJ,Courtenay O,Garcez L,Dye C

更新日期：1997-08-01 00:00:00

abstract：:Highly purified mitochondrial fractions have been isolated from the intraerythrocytic stages of two mammalian Plasmodium spp., Plasmodium yoelii of rodents and Plasmodium falciparum of man. Mitochondria of the former parasite are cristate whereas those of the latter are essentially acristate. Isolated mitochondria fro...

journal_title：Parasitology

authors： Fry M,Beesley JE

更新日期：1991-02-01 00:00:00

abstract：:Increased permeability of capillaries and venules, labelled with colloidal carbon, was observed in the superficial mucosa of the small intestine of sheep infected with Trichostrongylus colubriformis. The labelled vessels were restricted to infected portions of the gut, and the intensity of labelling appeared to be re...

journal_title：Parasitology

authors： Barker IK

更新日期：1975-04-01 00:00:00

abstract：:Human strongyloidiasis is a serious disease mostly attributable to Strongyloides stercoralis and to a lesser extent Strongyloides fuelleborni, a parasite mainly of non-human primates. The role of animals as reservoirs of human-infecting Strongyloides is ill-defined, and whether dogs are a source of human infection is ...

journal_title：Parasitology

authors： Barratt JLN,Sapp SGH

更新日期：2020-09-01 00:00:00

abstract：:An M13 phage random 12-mers peptide library was used to screen cathepsin L mimotopes of Fasciola hepatica and to evaluate their immunogenicity in sheep. Seven clones showed positive reactivity to a rabbit anti-cathepsin L1/L2 antiserum in ELISA, and their amino acid sequences deduced by DNA sequencing were tentatively...

journal_title：Parasitology

authors： Villa-Mancera A,Quiroz-Romero H,Correa D,Ibarra F,Reyes-Pérez M,Reyes-Vivas H,López-Velázquez G,Gazarian K,Gazarian T,Alonso RA

更新日期：2008-10-01 00:00:00

abstract：:Circumstantial evidence suggests that the earlier detachment of Boophilus microplus larvae from highly resistant cattle follows the release of histamine at the attachment site. In vivo and in vitro experiments show that a proportion of the larvae will detach following injection or infusion of histamine. Other mediator...

journal_title：Parasitology

authors： Kemp DH,Bourne A

更新日期：1980-06-01 00:00:00

abstract：:This study reports on morphological variability of Eimeria species, which may be given either by drawings or as quantitative data. The drawings may be used to facilitate identification by eye of 'unknown' Eimeria specimens, whereas quantitative data may serve as a reference set for identification by multivariate stati...

journal_title：Parasitology

authors： Sommer C

更新日期：1998-01-01 00:00:00

abstract：:Leishmania braziliensis strain M2903 was adapted for growth and serially maintained as amastigotes at 34 degrees C in modified UM-54 medium, with growth curves exhibiting typical log and stationary phases. In late passages, amastigote growth took place in the absence of supplementary haemin and was unaffected when the...

journal_title：Parasitology

authors： Balanco JM,Pral EM,da Silva S,Bijovsky AT,Mortara RA,Alfieri SC

更新日期：1998-02-01 00:00:00

abstract：:Past and more recent research has examined the ultrastructure, metabolism, cell biology, genomics and post-genomics of schistosome schistosomula. These areas are considered and discussed in this review with particular emphasis on (1) the early migration phases through the host, (2) interaction of the host immune respo...

journal_title：Parasitology

authors： Gobert GN,Chai M,McManus DP

更新日期：2007-04-01 00:00:00

abstract：:Biodiversity loss may increase the risk of infectious disease in a phenomenon known as the dilution effect. Circumstances that increase the likelihood of disease dilution are: (i) when hosts vary in their competence, and (ii) when communities disassemble predictably, such that the least competent hosts are the most li...

journal_title：Parasitology

authors： Stewart Merrill TE,Johnson PTJ

更新日期：2020-09-01 00:00:00

abstract：:An electron microscopical examination has been made of the fine structure and disposition of pancreatic polypeptide immunoreactive cells associated with the egg-forming apparatus in Diclidophora merlangi. The cell bodies are positioned in the parenchyma surrounding the ootype and taper to axon-like processes that exte...

journal_title：Parasitology

authors： Halton DW,Brennan GP,Maule AG,Shaw C,Johnston CF,Fairweather I

更新日期：1991-06-01 00:00:00

abstract：:Antigenic differences between intra-lymphocytic theilerial parasites isolated from the blood of 18 African buffalo and grown in vitro were assessed with anti-schizont monoclonal antibodies (mAbs). There was marked antigenic diversity both between isolates from different buffalo and between isolates taken at different ...

journal_title：Parasitology

authors： Conrad PA,Stagg DA,Grootenhuis JG,Irvin AD,Newson J,Njamunggeh RE,Rossiter PB,Young AS

更新日期：1987-06-01 00:00:00

abstract：:The flatworm nervous system employs a wide repertoire of neuroactive substances, including small chemical messengers, the so called classical transmitters, and several types of neuropeptides. A large body of research accumulated over four decades has provided a wealth of information on the tissue localization and effe...

journal_title：Parasitology

authors： Ribeiro P,El-Shehabi F,Patocka N

更新日期：2005-01-01 00:00:00