Asparaginyl endopeptidase activity in adult Schistosoma mansoni.

abstract：:Why do parasites kill their hosts? During this past decade, research in three different areas; evolutionary ecology, medical microbiology, and population genetics has provided theory and data that address this and related questions of selection and the evolution and maintenance of parasite virulence. A general theory ...

journal_title：Parasitology

authors： Levin BR,Svanborg Edén C

更新日期：1990-01-01 00:00:00

abstract：:Changes in host phenotype are often attributed to manipulation that enables parasites to complete trophic transmission cycles. We characterized changes in host phenotype in a colonial host–endoparasite system that lacks trophic transmission (the freshwater bryozoan Fredericella sultana and myxozoan parasite Tetracapsu...

journal_title：Parasitology

authors： Hartikainen H,Fontes I,Okamura B

更新日期：2013-09-01 00:00:00

abstract：:A deterministic mathematical model which predicts the probability of developing a new drug-resistant parasite population within the human host is reported. The model incorporates the host's specific antibody response to PfEMP1, and also investigates the influence of chemotherapy on the probability of developing a viab...

journal_title：Parasitology

authors： Gatton ML,Hogarth W,Saul A

更新日期：2001-12-01 00:00:00

abstract：:Traditionally, the family Campulidae has been associated either with the family Fasciolidae, parasites of ruminants, or the Acanthocolpidae, parasites of fishes, based on morphological similarities. Since morphology does not seem to resolve clearly the problem of the relationships of campulids, we have used the sequen...

journal_title：Parasitology

authors： Fernandez M,Littlewood DT,Latorre A,Raga JA,Rollinson D

更新日期：1998-10-01 00:00:00

abstract：:A cDNA clone codifying ribosomal protein L25 was isolated from a Leishmania braziliensis cDNA gene library. The alignment of the amino acid sequence deduced from this gene with other proteins revealed that this protein is related to the L23/25 rihosomal protein family. This is so because this protein shows, in its C-t...

journal_title：Parasitology

authors： González AC,Martínez E,Carmelo E,Piñero JE,Alonso V,Del Castillo A,Valladares B

更新日期：2002-07-01 00:00:00

abstract：:Recombinant ribosomal DNA sequences were amplified by PCR and used as probes to perform a fingerprint analysis of total DNA from different Entamoeba histolytica isolates. RFLPs obtained with one of the probes, R-1, support previous proposals that pathogenic and non-pathogenic E. histolytica are closely related, yet ge...

journal_title：Parasitology

authors： Cruz-Reyes JA,Spice WM,Rehman T,Gisborne E,Ackers JP

更新日期：1992-04-01 00:00:00

abstract：:The in vivo activity of two cyclosporins, cyclosporin A (CsA) and a non-immunosuppressive derivative of dihydrocylosporin A (DHCsA-d) against three tapeworms, Hymenolepis microstoma, H. diminuta and Mesocestoides corti, has been assessed. CsA reversibly reduced the dry weight of H. microstoma in the mouse, briefly del...

journal_title：Parasitology

authors： Chappell LH,Wastling JM,Hurd H

更新日期：1989-04-01 00:00:00

abstract：:Actively immunized mice, whole-body irradiated with 650 or 525 rad., manifested comparable levels of resistance to Schistosoma mansoni compared with unirradiated, immunized mice in spite of a marked reduction in circulating leucocytes (greater than 90%) and platelets (greater than 85%), and despite an abrogation of de...

journal_title：Parasitology

authors： Vignali DA,Bickle QD,Taylor MG

更新日期：1988-02-01 00:00:00

abstract：:Epidemiological rate parameters of host generalist parasites are difficult to estimate, especially in cases where variation in parasite performance can be attributed to host species. Such cases are likely common for generalist parasites of sympatric grazing mammals. In this study, we combined data from experimental ex...

journal_title：Parasitology

authors： Beck MA,Goater CP,Colwell DD

更新日期：2015-09-01 00:00:00

abstract：:We have studied the genomic organization and transcription of the histone H2A genes in the protozoan parasite Leishmania infantum. In the parasite genome 2 gene clusters exist, each containing 3 H2A gene copies. Sequence analyses showed the existence of significant sequence divergence among the H2A genes, mainly in th...

journal_title：Parasitology

authors： Soto M,Quijada L,Larreta R,Iborra S,Alonso C,Requena JM

更新日期：2003-08-01 00:00:00

abstract：:Taenia cestodes were obtained from 5 different definitive host species in Kenya and 175 different samples were examined by classical morphological methods and by isoenzyme analysis using isoelectric focusing in agarose. Gels were stained for 17 different enzymes and 3 of these were used in the construction of isoenzym...

journal_title：Parasitology

authors： Allsopp BA,Jones A,Allsopp MT,Newton SD,Macpherson CN

更新日期：1987-12-01 00:00:00

abstract：:In a population of copepods (Cyclops strenuus abyssorum), with a naturally high prevalence of infection with procercoids of Diphyllobothrium spp., no difference in body size was found between infected and uninfected hosts. However, a significant reduction in the reproductive capacity of infected females was observed, ...

journal_title：Parasitology

authors： Pasternak AF,Huntingford FA,Crompton DW

更新日期：1995-05-01 00:00:00

abstract：:Toxoplasmosis is largely present in rural areas but its spatial distribution in this environment remains poorly known. In particular, it is unclear if areas of high density of cats, the only hosts excreting Toxoplasma gondii, constitute foci of high prevalence. To improve our understanding of the spatial distribution ...

journal_title：Parasitology

authors： Gotteland C,Chaval Y,Villena I,Galan M,Geers R,Aubert D,Poulle ML,Charbonnel N,Gilot-Fromont E

更新日期：2014-02-01 00:00:00

abstract：:Isolates of Trypanosoma cruzi from human patients, domestic and sylvatic animals and vector insects were obtained in different areas of Argentina. Electrophoretic patterns of enzymes from extracts of 95 isolates were analysed. On the basis of zymograms providing information on 10 loci, 12 zymodemes are described accor...

journal_title：Parasitology

authors： de Luca D'oro GM,Gardenal CN,Perret B,Crisci JV,Montamat EE

更新日期：1993-11-01 00:00:00

abstract：:Pinewood nematode, Bursaphelenchus xylophilus, a pine parasitic nematode, poses a serious threat to its host pine forests globally. When dispersal-stage larvae 4 (dauer, DL4) of B. xylophilus enters the new pine, it moults into propagative adult (dauer recovery) and reproduces quickly to kill the host pine. Here, we f...

journal_title：Parasitology

authors： Zhang W,Li Y,Pan L,Wang X,Feng Y,Zhang X

更新日期：2020-01-01 00:00:00

abstract：:Treatment of BALB/c or MF1 mice with cyclosporin A (CsA) around the time of infection with Schistosoma mansoni conferred almost complete protection. The migration kinetics of L-[75Se]selenomethionine-labelled infective cercariae were investigated by compressed tissue autoradiography. Similar levels of skin penetration...

journal_title：Parasitology

authors： Munro GH,Brannan LR,Chappell LH,Thomson AW,McLaren DJ

更新日期：1991-02-01 00:00:00

abstract：:Several approaches were adopted for the disruption and removal of the tegumental surface from protoscoleces of the horse strain of the hydatid organism, Echinococcus granulosus. The effectiveness of each method and the purity of subsequent microthrix-enriched fractions obtained by differential centrifugation were eval...

journal_title：Parasitology

authors： McManus DP,Barrett NJ

更新日期：1985-02-01 00:00:00

abstract：:Strongyloides ratti is a parasitic nematode of rats. The host immune response against S. ratti affects the development of its free-living generation, favouring the development of free-living adult males and females at the expense of directly developing, infective 3rd-stage larvae. However, how the host immune response...

journal_title：Parasitology

authors： Crook M,Viney ME

更新日期：2005-09-01 00:00:00

abstract：:Voltage-gated calcium (Ca2+) channels contribute to impulse propagation in excitable cells and also regulate intracellular levels of Ca2+. High voltage-activated (HVA) Ca2+ channels are heteromultimeric membrane proteins. The pore-forming, voltage-sensing subunit is the alpha1 subunit. We have cloned 3 HVA Ca2+ channe...

journal_title：Parasitology

authors： Kohn AB,Lea J,Roberts-Misterly JM,Anderson PA,Greenberg RM

更新日期：2001-11-01 00:00:00

abstract：:This paper investigates a cohort of 2187 laboratory reared Culex quinquefasciatus fed on 69 human volunteers, including 59 persons with different levels of Wuchereria bancrofti microfilariae and 10 without microfilaria. Mosquitoes were followed until death. Mosquito survival was analysed in relation to the level of mi...

journal_title：Parasitology

authors： Krishnamoorthy K,Subramanian S,Van Oortmarssen GJ,Habbema JD,Das PK

更新日期：2004-07-01 00:00:00

abstract：:Climate change, in particular rising temperature, is suspected to be a major driver for the emergence of many wildlife diseases. Proliferative kidney disease of salmonids, caused by the myxozoan Tetracapsuloides bryosalmonae, was used to evaluate how temperature dependence of host-parasite interactions modulates disea...

journal_title：Parasitology

authors： Strepparava N,Segner H,Ros A,Hartikainen H,Schmidt-Posthaus H,Wahli T

更新日期：2018-03-01 00:00:00

abstract：:The group of haemosporidian parasites is of general interest to basic and applied science, since several species infect mammals, leading to malaria and associated disease symptoms. Although the great majority of haemosporidian parasites appear in bird hosts, as in the case of Leucocytozoon buteonis, there is little ge...

journal_title：Parasitology

authors： Chakarov N,Greiner JF,Hauser S,Schuetzmann D,Krüger O,Boerner M,Wıdera D

更新日期：2012-10-01 00:00:00

abstract：:Endotoxaemia has been described in cases of Human African trypanosomiasis (HAT), but it is unclear if this phenomenon influences inflammatory pathology either in the periphery or central nervous system (CNS). We studied endotoxin concentrations in the plasma and cerebrospinal fluid (CSF) of Trypanosoma brucei rhodesie...

journal_title：Parasitology

authors： Maclean L,Aboubaker EA,Kennedy PG,Sternberg JM

更新日期：2017-04-01 00:00:00

abstract：:Existing models of the basic case reproduction number (R0) for vector-borne diseases assume (i) that the distribution of vectors over the susceptible host species is homogeneous and (ii) that the biting preference for the susceptible host species rather than other potential hosts is a constant. Empirical evidence cont...

journal_title：Parasitology

authors： Kelly DW,Thompson CE

更新日期：2000-03-01 00:00:00

abstract：:The cumulative effect of co-infections between pathogen pairs on the haematological response of East African Short-horn Zebu calves is described. Using a longitudinal study design a stratified clustered random sample of newborn calves were recruited into the Infectious Diseases of East African Livestock (IDEAL) study ...

journal_title：Parasitology

authors： Van Wyk IC,Goddard A,de C Bronsvoort BM,Coetzer JA,Handel IG,Hanotte O,Jennings A,Lesosky M,Kiara H,Thumbi SM,Toye P,Woolhouse MW,Penzhorn BL

更新日期：2014-03-01 00:00:00

abstract：:In this study, the proteome of axenically grown Entamoeba histolytica parasites was explored by two-dimensional gel electrophoresis (2-DE), employing a practical and effective procedure for the solubilization of E. histolytica proteins. Approximately 900 protein species in the pH range between 4 and 7 were detected by...

journal_title：Parasitology

authors： Tolstrup J,Krause E,Tannich E,Bruchhaus I

更新日期：2007-02-01 00:00:00

abstract：:Trypanosoma cruzi, causative agent of Chagas disease, co-infects its triatomine vector with its sister species Trypanosoma rangeli, which shares 60% of its antigens with T. cruzi. Additionally, T. rangeli has been observed to be pathogenic in some of its vector species. Although T. cruzi-T. rangeli co-infections are c...

journal_title：Parasitology

authors： Peterson JK,Graham AL,Elliott RJ,Dobson AP,Triana Chávez O

更新日期：2016-08-01 00:00:00

abstract：:SSU ribosomal sequences of trypanosomes from Brazilian cattle and water buffalo were used to infer phylogenetic relationships between non-pathogenic T. theileri and allied species parasitic in artiodactyls. T. theileri trypanosomes from distinct geographical regions in Brazil and from other countries were tightly clus...

journal_title：Parasitology

authors： Rodrigues AC,Paiva F,Campaner M,Stevens JR,Noyes HA,Teixeira MM

更新日期：2006-02-01 00:00:00

abstract：:The gastrointestinal nematodes (GIN) stand out as an important cause of disease in small ruminant, especially on goat farm. Widespread resistance to synthetic anthelminthics has stimulated the research for alternative strategies of parasite control, including the use of medicinal plants. The present work summarizes th...

journal_title：Parasitology

authors： Oliveira Santos F,Ponce Morais Cerqueira A,Branco A,José Moreira Batatinha M,Borges Botura M

更新日期：2019-09-01 00:00:00

abstract：:Understanding the origin of invasive parasites and ecological transmission barriers on the distribution of mosquito-borne pathogens is enriched by molecular phylogenetic approaches now that large databases are becoming available. Here we assess the biogeographical relationships among haemosporidian blood parasites and...

journal_title：Parasitology

authors： Baillie SM,Brunton DH

更新日期：2011-12-01 00:00:00