Parasitism and phenotypic change in colonial hosts.


:Changes in host phenotype are often attributed to manipulation that enables parasites to complete trophic transmission cycles. We characterized changes in host phenotype in a colonial host–endoparasite system that lacks trophic transmission (the freshwater bryozoan Fredericella sultana and myxozoan parasite Tetracapsuloides bryosalmonae). We show that parasitism exerts opposing phenotypic effects at the colony and module levels. Thus, overt infection (the development of infectious spores in the host body cavity) was linked to a reduction in colony size and growth rate, while colony modules exhibited a form of gigantism. Larger modules may support larger parasite sacs and increase metabolite availability to the parasite. Host metabolic rates were lower in overtly infected relative to uninfected hosts that were not investing in propagule production. This suggests a role for direct resource competition and active parasite manipulation (castration) in driving the expression of the infected phenotype. The malformed offspring (statoblasts) of infected colonies had greatly reduced hatching success. Coupled with the severe reduction in statoblast production this suggests that vertical transmission is rare in overtly infected modules. We show that although the parasite can occasionally infect statoblasts during overt infections, no infections were detected in the surviving mature offspring, suggesting that during overt infections, horizontal transmission incurs a trade-off with vertical transmission.






Hartikainen H,Fontes I,Okamura B




Has Abstract


2013-09-01 00:00:00














  • Schistosoma mansoni phosphofructokinase: immunolocalization in the tegument and immunogenicity.

    abstract::Schistosoma mansoni depends for its survival on glycolysis. Two glycolytic enzymes, glyceraldehyde-3P-dehydrogenase and triose-phosphate dehydrogenase, found in both the adult and schistosomular tegument, have been reported to confer partial protection against cercarial infection. This paper describes the immunogenic ...


    pub_type: 杂志文章


    authors: Mansour JM,McCrossan MV,Bickle QD,Mansour TE

    更新日期:2000-05-01 00:00:00

  • Immunochemical analysis of surface membrane antigens on erythrocytes infected with non-cloned SICA[+] or cloned SICA[-] Plasmodium knowlesi.

    abstract::The SICA[-] or non-agglutinable phenotype of Plasmodium knowlesi schizont-infected erythrocytes has been defined serologically but not biochemically. Similarly, non-cloned SICA[+] or agglutinable parasites have been shown serologically to express SICA or variant antigen(s) but the number and nature of such antigens ha...


    pub_type: 杂志文章


    authors: Howard RJ,Barnwell JW

    更新日期:1985-10-01 00:00:00

  • The degradation rates of cytoplasmic tRNA, rRNA and mRNA in rats are elevated after infection with Nippostrongylus brasiliensis.

    abstract::The effects of a parasitic infection with the nematode Nippostrongylus brasiliensis on the degradation rates of cytoplasmic tRNA, rRNA and mRNA in rats have been investigated by measuring the renal excretion rates of the modified RNA catabolites N6-threoninocarbonyladenosine, pseudouridine and 7-methylguanine. Between...


    pub_type: 杂志文章


    authors: Topp H,Duden R,Stephan U,Schöch G

    更新日期:1998-02-01 00:00:00

  • Host and ecology both play a role in shaping distribution of digenean parasites of New Zealand whelks (Gastropoda: Buccinidae: Cominella).

    abstract::Digenean parasites infecting four Cominella whelk species (C. glandiformis, C. adspersa, C. maculosa and C. virgata), which inhabit New Zealand's intertidal zone, were analysed using molecular techniques. Mitochondrial 16S and cytochrome oxidase 1 (COI) and nuclear rDNA ITS1 sequences were used to infer phylogenetic r...


    pub_type: 杂志文章


    authors: Donald KM,Spencer HG

    更新日期:2016-08-01 00:00:00

  • Matrix metalloproteinases mediate the metastatic phenotype of Theileria annulata-transformed cells.

    abstract::Theileria annulata infects and reversibly transforms bovine leucocytes. The parasite-transformed cells are immortalized, metastatic and express a number of metalloproteinases including matrix metalloproteinase 9 which they secrete. All the metalloproteinases observed on substrate gels are inhibited by tissue inhibitor...


    pub_type: 杂志文章


    authors: Adamson RE,Hall FR

    更新日期:1996-11-01 00:00:00

  • Cytoadherence of knobby and knobless Plasmodium falciparum-infected erythrocytes.

    abstract::Cytoadherence of Plasmodium falciparum-infected erythrocytes to melanoma cells was analysed using strains or isolates of parasites expressing or not expressing knobs (K+ or K- phenotype) on the erythrocyte surface. Both K+ and K- parasites had the capacity to cytoadhere to melanoma cells. Using a panel of melanoma cel...


    pub_type: 杂志文章


    authors: Ruangjirachuporn W,Afzelius BA,Paulie S,Wahlgren M,Berzins K,Perlmann P

    更新日期:1991-06-01 00:00:00

  • Induction of immunity in sheep to Fasciola hepatica with mimotopes of cathepsin L selected from a phage display library.

    abstract::An M13 phage random 12-mers peptide library was used to screen cathepsin L mimotopes of Fasciola hepatica and to evaluate their immunogenicity in sheep. Seven clones showed positive reactivity to a rabbit anti-cathepsin L1/L2 antiserum in ELISA, and their amino acid sequences deduced by DNA sequencing were tentatively...


    pub_type: 杂志文章


    authors: Villa-Mancera A,Quiroz-Romero H,Correa D,Ibarra F,Reyes-Pérez M,Reyes-Vivas H,López-Velázquez G,Gazarian K,Gazarian T,Alonso RA

    更新日期:2008-10-01 00:00:00

  • Species delimitation in trematodes using DNA sequences: Middle-American Clinostomum as a case study.

    abstract::The recent development of genetic methods allows the delineation of species boundaries, especially in organisms where morphological characters are not reliable to differentiate species. However, few empirical studies have used these tools to delineate species among parasitic metazoans. Here we investigate the species ...


    pub_type: 杂志文章


    authors: Pérez-Ponce DE León G,García-Varela M,Pinacho-Pinacho CD,Sereno-Uribe AL,Poulin R

    更新日期:2016-11-01 00:00:00

  • The three-spined stickleback-Schistocephalus solidus system: an experimental model for investigating host-parasite interactions in fish.

    abstract::Plerocercoids of the pseudophyllidean cestode Schistocephalus solidus infect the three-spined stickleback Gasterosteus aculeatus, with important consequences for the biology of host fish. Techniques for culturing the parasite in vitro and generating infective stages that can be used to infect sticklebacks experimental...


    pub_type: 杂志文章


    authors: Barber I,Scharsack JP

    更新日期:2010-03-01 00:00:00

  • What helminth genomes have taught us about parasite evolution.

    abstract::The genomes of more than 20 helminths have now been sequenced. Here we perform a meta-analysis of all sequenced genomes of nematodes and Platyhelminthes, and attempt to address the question of what are the defining characteristics of helminth genomes. We find that parasitic worms lack systems for surface antigenic var...


    pub_type: 杂志文章,meta分析,评审


    authors: Zarowiecki M,Berriman M

    更新日期:2015-02-01 00:00:00

  • Thymus-independent crypt hyperplasia and villous atrophy in the small intestine of mice infected with the trematode Echinostoma revolutum.

    abstract::Conventional mice and congenitally athymic, nude mice were infected with 20 metacercariae of the intestinal trematode Echinostoma revolutum. The sequential events in the pathological changes in the intestine were studied at different intervals post-infection. By day 11 onwards the conventional mice displayed dilatatio...


    pub_type: 杂志文章


    authors: Bindseil E,Christensen NO

    更新日期:1984-06-01 00:00:00

  • Genetic variation among lambs in peripheral IgE activity against the larval stages of Teladorsagia circumcincta.

    abstract::IgA and IgE activity against Teladorsagia circumcincta was investigated in a flock of Texel lambs following natural, mixed nematode infection among lambs. The distribution of IgA activity was similar to a gamma distribution whereas IgE activity was different. Box-Cox analysis demonstrated that X0.25 was a suitable tra...


    pub_type: 杂志文章


    authors: Murphy L,Eckersall PD,Bishop SC,Pettit JJ,Huntley JF,Burchmore R,Stear MJ

    更新日期:2010-07-01 00:00:00

  • Isolation, fractionation and partial characterization of the tegumental surface from protoscoleces of the hydatid organism, Echinococcus granulosus.

    abstract::Several approaches were adopted for the disruption and removal of the tegumental surface from protoscoleces of the horse strain of the hydatid organism, Echinococcus granulosus. The effectiveness of each method and the purity of subsequent microthrix-enriched fractions obtained by differential centrifugation were eval...


    pub_type: 杂志文章


    authors: McManus DP,Barrett NJ

    更新日期:1985-02-01 00:00:00

  • Developmental changes of Echinococcus multilocularis metacestodes revealed by tegumental ultrastructure and lectin-binding sites.

    abstract::Ultrastructural investigations (SEM, TEM) combined with lectin-binding analysis, have revealed concurrent modifications in tegumentary structure and surface glycoconjugates during the establishment and differentiation of Echinococcus multilocularis metacestodes in jirds. The laminated layer, which is amorphous and ric...


    pub_type: 杂志文章


    authors: Leducq R,Gabrion C

    更新日期:1992-02-01 00:00:00

  • Evidence that primary infection of Charollais sheep with Toxoplasma gondii may not prevent foetal infection and abortion in subsequent lambings.

    abstract::A study carried out on a sheep farm examined whether Toxoplasma gondii foetal infection and associated abortion occur in successive lambings. We identified 29 ewes that gave birth to lambs on at least 2 successive years over our study period, 2000-2003. Tissue samples from the progeny of these ewes were analysed by PC...


    pub_type: 杂志文章


    authors: Morley EK,Williams RH,Hughes JM,Thomasson D,Terry RS,Duncanson P,Smith JE,Hide G

    更新日期:2008-02-01 00:00:00

  • The amount of acetylcholinesterase on the parasite surface reflects the differential sensitivity of schistosome species to metrifonate.

    abstract::Acetylcholinesterase (AChE) is present in all stages of the life-cycle of schistosomes and is located in muscle and on the surface of the parasite. Metrifonate is a drug that inhibits AChE. We compared the AChEs from three schistosome species (Schistosoma mansoni, Schistosoma haematobium and Schistosoma bovis) that ha...


    pub_type: 杂志文章


    authors: Camacho M,Tarrab-Hazdai R,Espinoza B,Arnon R,Agnew A

    更新日期:1994-02-01 00:00:00

  • Dipstick dot ELISA for the detection of Taenia coproantigens in humans.

    abstract::A dipstick dot ELISA for detection of Taenia-specific coproantigens was developed. The test was based on a sandwich ELISA using antibodies raised against adult Taenia solium. Antibodies were absorbed to nitrocellulose paper previously adhered to acetate plastic to form dipsticks. Once blocked with 5% skimmed milk and ...


    pub_type: 杂志文章


    authors: Allan JC,Mencos F,Garcia-Noval J,Sarti E,Flisser A,Wang Y,Liu D,Craig PS

    更新日期:1993-07-01 00:00:00

  • A second peak of egg excretion in Strongyloides ratti-infected rats: its origin and biological meaning.

    abstract::In Strongyloides ratti-infected rats, 2 peaks of egg excretion were observed; a large one with maximum egg production on days 7-8 of infection and a small more inconspicuous one around day 25. The second peak, which had been ignored in most studies, was produced by adults in the caecum and the colon. The adults were l...


    pub_type: 杂志文章


    authors: Kimura E,Shintoku Y,Kadosaka T,Fujiwara M,Kondo S,Itoh M

    更新日期:1999-08-01 00:00:00

  • Mechanisms of mortality in Culicoides biting midges due to Haemoproteus infection.

    abstract::We examined the effects of Haemoproteus infection on the survival and pathology caused in the biting midges. Forty-six females of Culicoides impunctatus were exposed experimentally by allowing them to feed on a naturally infected red-backed shrike infected with Haemoproteus lanii (lineage hRB1, gametocytaemia 5·2%). S...


    pub_type: 杂志文章


    authors: Bukauskaitė D,Bernotienė R,Iezhova TA,Valkiūnas G

    更新日期:2016-11-01 00:00:00

  • Marine parasites as pollution indicators: an update.

    abstract::Eight major reviews are cited to indicate a recent knowledge explosion on the use of marine parasites as potential indicators of pollution. A literature update is given for the period 1995-2001. An analysis of the publications cited is used to provide 10 refined criteria for selecting parasites as indicator/monitor sp...


    pub_type: 杂志文章,评审


    authors: Williams HH,MacKenzie K

    更新日期:2003-01-01 00:00:00

  • Female mice mate preferentially with non-parasitized males.

    abstract::If parasitic infection is a driving force in female mate choice, then females should preferentially select parasite-free males. The role of infection on female mate choice in mammals was assessed using a 3-chambered apparatus. A female CD-1 mouse was allowed to choose between 2 tethered male mice, 1 uninfected and 1 i...


    pub_type: 杂志文章


    authors: Ehman KD,Scott ME

    更新日期:2002-11-01 00:00:00

  • Lethality of intestinal tissue extracts from Eimeria-infected chickens.

    abstract::Evidence exists that lethal activity is associated with extracts from Eimeria tenella-infected caecal tissues. We examined tissues of the small intestine infected with other species of Eimeria for a similar lethal activity. Extracts were prepared from intestinal tissues of chickens infected with either E. acervulina, ...


    pub_type: 杂志文章


    authors: McKenzie ME,Johnson J,Long PL

    更新日期:1985-06-01 00:00:00

  • The reproductive effort of Lepeophtheirus pectoralis (Copepoda: Caligidae): insights into the egg production strategy of parasitic copepods.

    abstract::The reproductive effort of Lepeophtheirus pectoralis (Müller O. F., 1776), a caligid copepod, which is commonly found infecting the European flounder, Platichthys flesus (Linnaeus, 1758), is studied in detail for the first time. Seasonal variation in body dimensions and reproductive effort are analysed. Data for 120 o...


    pub_type: 杂志文章


    authors: Frade DG,Santos MJ,Cavaleiro FI

    更新日期:2016-01-01 00:00:00

  • Synthesis and degradation of glycogen by Schistosoma mansoni worms in vitro.

    abstract::The glycogen stores of adult Schistosoma mansoni worms could be labelled by incubation of the worms, after an initial reduction of their glycogen content, in the presence of [6-14C]glucose. Subsequent breakdown of the labelled glycogen by the parasite revealed that glycogen was degraded to lactate and carbon dioxide. ...


    pub_type: 杂志文章


    authors: Tielens AG,Celik C,Van den Heuvel JM,Elfring RH,Van den Bergh SG

    更新日期:1989-02-01 00:00:00

  • Pathophysiology of parasitic infections.

    abstract::Parasites can have a wide range of pathophysiological effects on the host. This review describes those associated with some parasites of major importance in man and animals. Haemoprotozoan diseases such as trypanosomiasis and malaria are primarily associated with anaemia. Such anaemias have a complex aetiology involvi...


    pub_type: 杂志文章,评审


    authors: Holmes PH

    更新日期:1987-01-01 00:00:00

  • Is sex-biased ectoparasitism related to sexual size dimorphism in small mammals of Central Europe?

    abstract::Sexual size dimorphism (SSD) in mammals reveals the extent of sexual selection, which may in turn explain why males are often more infected by parasites than females and that parasites may contribute to the association between SSD and male-biased mortality. Here, we investigated the relationship between SSD in small m...


    pub_type: 杂志文章


    authors: Morand S,De Bellocq JG,Stanko M,Miklisová D

    更新日期:2004-10-01 00:00:00

  • The larvicidal activity of cyclosporin A against Schistosoma mansoni in mice.

    abstract::Treatment of BALB/c or MF1 mice with cyclosporin A (CsA) around the time of infection with Schistosoma mansoni conferred almost complete protection. The migration kinetics of L-[75Se]selenomethionine-labelled infective cercariae were investigated by compressed tissue autoradiography. Similar levels of skin penetration...


    pub_type: 杂志文章


    authors: Munro GH,Brannan LR,Chappell LH,Thomson AW,McLaren DJ

    更新日期:1991-02-01 00:00:00

  • Guinea worm: from Robert Leiper to eradication.

    abstract::Guinea worm disease, dracunculiasis or dracontiasis, is an ancient disease with records going back over 4500 years, but until the beginning of the 20th century, little was known about its life cycle, particularly how humans became infected. In 1905, Robert Thomas Leiper was sent by the British colonial authorities to ...


    pub_type: 传,历史文章,杂志文章,评审


    authors: Tayeh A,Cairncross S,Cox FEG

    更新日期:2017-10-01 00:00:00

  • Egg hatching in 3 species of monocotylid monogenean parasites from the shovelnose ray Rhinobatos typus at Heron Island, Australia.

    abstract::Eggs of Neoheterocotyle rhinobatidis, Troglocephalus rhinobatidis and Merizocotyle icopae (Monogenea: Monocotylidae) from the shovelnose ray Rhinobatos typus (Rhinobatidae) have a distinct hatching pattern linked to light periodicity. Larvae of these 3 monogenean species emerge only during daylight when exposed to nat...


    pub_type: 杂志文章


    authors: Chisholm LA,Whittington ID

    更新日期:2000-09-01 00:00:00

  • Membrane localization and demonstration of isoforms of nucleoside triphosphate hydrolase from Toxoplasma gondii.

    abstract::Toxoplasma gondii has a unique enzyme, a NTPase, which has a wide specificity toward NTP. In the present study, we produced a monoclonal antibody (IgG1, 6C6) against the enzyme which could recognize NTPase isozymes among several strains of T. gondii. Three avirulent strains of T. gondii, ME49, Beverley and Nakayama, w...


    pub_type: 杂志文章


    authors: Kikuchi T,Furuta T,Kojima S

    更新日期:2001-01-01 00:00:00