Boophilus microplus: the effect of histamine on the attachment of cattle-tick larvae--studies in vivo and in vitro.

Abstract:

:Circumstantial evidence suggests that the earlier detachment of Boophilus microplus larvae from highly resistant cattle follows the release of histamine at the attachment site. In vivo and in vitro experiments show that a proportion of the larvae will detach following injection or infusion of histamine. Other mediators such as bradykinin, prostaglandin E2, 5-hydroxytryptamine and dopamine have little or no effect on tick behaviour in vivo. Sensitivity to histamine declines as larval attachments stabilize, and repeated injections have no effect on the weight of larvae after 3 days on the host. Response to histamine is discussed in relation to host resistance, histology of the feeding lesion and larval behaviour.

journal_name

Parasitology

journal_title

Parasitology

authors

Kemp DH,Bourne A

doi

10.1017/s0031182000000950

subject

Has Abstract

pub_date

1980-06-01 00:00:00

pages

487-96

issue

3

eissn

0031-1820

issn

1469-8161

journal_volume

80

pub_type

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