Purification and characterization of a saccharide-binding protein from penetration glands of Diplostomum pseudospathaceum--a bifunctional molecule with cysteine protease activity.

abstract：:Flow cytometric analysis of the binucleated protozoan parasite Giardia intestinalis gave DNA histograms with a broad G1 peak and a definable G2 + M peak with twice the DNA content of G1. Twenty-four hour treatment with metronidazole arrested cell cycle progression of susceptible trophozoites in the G2 + M phase, but h...

journal_title：Parasitology

authors： Hoyne GF,Boreham PF,Parsons PG,Ward C,Biggs B

更新日期：1989-12-01 00:00:00

abstract：:Ligand-gated chloride channels (LGCCs) are key components of the nervous system of parasitic nematodes and important targets for anthelmintics. Here, we describe the isolation and characterization of a novel member of the LGCC gene family (HcLGCC1) from the parasitic nematode Haemonchus contortus. Sequence analysis re...

journal_title：Parasitology

authors： Forrester SG,Siddiqui SZ

更新日期：2008-04-01 00:00:00

abstract：:Theileria-free waterbuck (Kobus defassa) born in captivity were successfully infected with Theileria parva sporozoites derived from ticks infected by feeding on African buffalo (Syncerus caffer). All waterbuck underwent mild infections with the development of sporadic schizont and piroplasm parasitosis when inoculated...

journal_title：Parasitology

authors： Stagg DA,Bishop RP,Morzaria SP,Shaw MK,Wesonga D,Orinda GO,Grootenhuis JG,Molyneux DH,Young AS

更新日期：1994-06-01 00:00:00

abstract：:This review of protozoan and helminth infections in pregnancy focuses on the impact on the immune response in the newborn infant to maternal infection. Studies of protozoan and helminth infections in pregnant women and in their offspring have shown that children exposed to antigens or microorganisms during pregnancy o...

journal_title：Parasitology

authors： Petersen E

更新日期：2007-01-01 00:00:00

abstract：:Solid experimental evidence indicates that EBA-175 is used as a ligand by the Plasmodium falciparum merozoite to bind to human RBC, via different binding processing fragments. Using synthetic peptides and specific receptor-ligand interaction methodology, we have identified 6 high-activity binding sequences from the EB...

journal_title：Parasitology

authors： Rodriguez LE,Urquiza M,Ocampo M,Suarez J,Curtidor H,Guzman F,Vargas LE,Triviños M,Rosas M,Patarroyo ME

更新日期：2000-03-01 00:00:00

abstract：:A comparison has been made of the responses of random-bred CFLP and inbred NIH mice to infection with Trichuris muris. Random-bred mice showed greater variation in worm burdens and less uniformity in worm expulsion. Irradiation prior to infection reduced variation, but did not increase the mean level of infection abov...

journal_title：Parasitology

authors： Wakelin D

更新日期：1975-08-01 00:00:00

abstract：:An electron microscopical study was made on the development of Eimeria dispersa in the small intestine of the domestic turkey. Turkey poults, 10-14 days of age, were inoculated with oocysts and pieces of intestinal tissue were fixed at intervals between 3.5 and 114 h after inoculation. Sporozoites were occasionally se...

journal_title：Parasitology

authors： Millard BJ,Lawn AM

更新日期：1982-02-01 00:00:00

abstract：:A one-year study of gastro-intestinal parasitism in a free-ranging population of maras at Whipsnade Wild Animal Park, UK, revealed a strong relationship between membership of social units and both intensity and prevalence of infection. The mara, a hystricomorph rodent from southern Argentina, has a social organization...

journal_title：Parasitology

authors： Porteous IS,Pankhurst SJ

更新日期：1998-03-01 00:00:00

abstract：:The pentastomid parasite, Raillietiella frenata, is native to Asia where it infects the Asian House gecko, Hemidactylus frenatus. This gecko has been widely introduced and recently R. frenata was found in introduced populations of cane toads (Rhinella marina) in Australia, indicating a host-switch from introduced geck...

journal_title：Parasitology

authors： Kelehear C,Saltonstall K,Torchin ME

更新日期：2015-04-01 00:00:00

abstract：:The efficiency of treatment of human infections with the unicellular eukaryotic pathogens such as fungi and protozoa remains deeply unsatisfactory. For example, the mortality rates from nosocomial fungemia in critically ill, immunosuppressed or post-cancer patients often exceed 50%. A set of six systemic clinical azol...

journal_title：Parasitology

authors： Lepesheva GI,Friggeri L,Waterman MR

更新日期：2018-12-01 00:00:00

abstract：:The ultrastructure of the formation of the first-stage cuticle within the egg of Trichostrongylus colubriformis is described. The first indication of cuticle formation was the formation of the epicuticle external to the epidermal plasma membrane. This becomes thickened to form the epicuticle of the fully formed cuticl...

journal_title：Parasitology

authors： Wharton DA,Bone LW

更新日期：1988-12-01 00:00:00

abstract：:The transmission success of Onchocerca volvulus is thought to be influenced by a variety of regulatory or density-dependent processes that act at various points in the two-host life-cycle. This paper examines one component of the life-cycle, namely, the ingestion of microfilariae by the simuliid vector, to assess the ...

journal_title：Parasitology

authors： Basáñez MG,Boussinesq M,Prod'hon J,Frontado H,Villamizar NJ,Medley GF,Anderson RM

更新日期：1994-01-01 00:00:00

abstract：:Sera from goats and cattle that were infected with two Trypanosoma vivax clones (ILDat 1.2 and ILDat 2.1) derived from different stocks were analysed for antibody activity against the variable surface glycoproteins (VSGs) of the infecting clones by enzyme-linked immune assays (ELISA) and immune lysis. To obtain purifi...

journal_title：Parasitology

authors： Vos GJ,Gardiner PR

更新日期：1990-02-01 00:00:00

abstract：:Changes in the cardiac beta-adrenergic system in early stages of Trypanosoma cruzi infection have been described. Here, we studied an early (135 days post-infection-p.i.) and a late stage (365 days p.i.) of the cardiac chronic form of the experimental infection (Tulahuen or SGO-Z12 strains), determining plasma epineph...

journal_title：Parasitology

authors： Lo Presti MS,Rivarola HW,Fernández AR,Enders JE,Levin G,Fretes R,Cerban FM,Garrido VV,Paglini-Oliva P

更新日期：2009-07-01 00:00:00

abstract：:Given the worldwide decline of amphibian populations due to emerging infectious diseases, it is imperative that we identify and address the causative agents. Many of the pathogens recently implicated in amphibian mortality and morbidity have been fungal or members of a poorly understood group of fungus-like protists, ...

journal_title：Parasitology

authors： Raffel TR,Bommarito T,Barry DS,Witiak SM,Shackelton LA

更新日期：2008-02-01 00:00:00

abstract：:Oligosaccharides are broadly present on Leishmania cell surfaces. They can be useful for the leishmaniases diagnosis and also helpful in identifying new cell markers for the disease. The disaccharide Galα1-3Galβ is the immunodominant saccharide in Leishmania cell surface and is the unique non-reducing terminal glycosp...

journal_title：Parasitology

authors： de Souza LMB,Thomaz Soccol V,Petterle RR,Bates MD,Bates PA

更新日期：2018-12-01 00:00:00

abstract：:Bat flies are obligate ectoparasites of bats and it has been hypothesized that they may be involved in the transmission of Bartonella species between bats. A survey was conducted to identify whether Cyclopodia greefi greefi (Diptera: Nycteribiidae) collected from Ghana and 2 islands in the Gulf of Guinea harbour Barto...

journal_title：Parasitology

authors： Billeter SA,Hayman DT,Peel AJ,Baker K,Wood JL,Cunningham A,Suu-Ire R,Dittmar K,Kosoy MY

更新日期：2012-03-01 00:00:00

abstract：:A thymine-uracil transport system is present in the plasma membrane brush-border of the tapeworm, Hymenolepis diminuta. The relation between initial uptake and substrate concentration of either thymine or uracil was sigmoidal when 2-14C-labelled substrates were used. In contrast, absorption kinetics of methyl-14C- and...

journal_title：Parasitology

authors： Uglem GL,Dupre RK,Harley JP

更新日期：1983-10-01 00:00:00

abstract：:In areas where malaria is endemic, helminthic infections, caused by intestinal or filarial parasites, commonly coexist with malaria in the same individual. This study investigates the course of Plasmodium berghei malaria infection in CBA/J mice inoculated with irradiated attenuated 3rd-stage larvae (L3) of Brugia paha...

journal_title：Parasitology

authors： Yan Y,Inuo G,Akao N,Tsukidate S,Fujita K

更新日期：1997-04-01 00:00:00

abstract：:Changes during development in the elemental contents (Ca, P, K, Mg and S) of male and female Schistosoma mansoni from both mixed and single sex infections have been measured for the first time. In mixed infections, there is a significant difference between the calcium content of male and female worms; female worms hav...

journal_title：Parasitology

authors： Shaw MK,Erasmus DA

更新日期：1983-06-01 00:00:00

abstract：:Trypanosoma cruzi, causative agent of Chagas disease, co-infects its triatomine vector with its sister species Trypanosoma rangeli, which shares 60% of its antigens with T. cruzi. Additionally, T. rangeli has been observed to be pathogenic in some of its vector species. Although T. cruzi-T. rangeli co-infections are c...

journal_title：Parasitology

authors： Peterson JK,Graham AL,Elliott RJ,Dobson AP,Triana Chávez O

更新日期：2016-08-01 00:00:00

abstract：:This study characterized antigens of Trichinella spiralis and T. pseudospiralis muscle larvae recognized by mice infected with the worms. Two-dimensional (2-D) Western blot analysis revealed some profile of antigenic peptides including: (1) molecular weight (MW); (2) isoelectric points (pI), (3) reactivity to well-def...

journal_title：Parasitology

authors： Wu Z,Nagano I,Takahashi Y

更新日期：1999-06-01 00:00:00

abstract：:Taenia cestodes were obtained from 5 different definitive host species in Kenya and 175 different samples were examined by classical morphological methods and by isoenzyme analysis using isoelectric focusing in agarose. Gels were stained for 17 different enzymes and 3 of these were used in the construction of isoenzym...

journal_title：Parasitology

authors： Allsopp BA,Jones A,Allsopp MT,Newton SD,Macpherson CN

更新日期：1987-12-01 00:00:00

abstract：:Parasites can have a wide range of pathophysiological effects on the host. This review describes those associated with some parasites of major importance in man and animals. Haemoprotozoan diseases such as trypanosomiasis and malaria are primarily associated with anaemia. Such anaemias have a complex aetiology involvi...

journal_title：Parasitology

authors： Holmes PH

更新日期：1987-01-01 00:00:00

abstract：:Cyst fluid (CF) of Taenia solium metacestode (TsM) is an important source of serodiagnostic antigens. We have investigated the molecular characteristics of the 120 kDa protein complex in TsM CF purified by fast performance liquid chromatography. The structure of the purified protein was characterized by a variety of p...

journal_title：Parasitology

authors： Lee EG,Bae YA,Jeong YT,Chung JY,Je EY,Kim SH,Na BK,Ju JW,Kim TS,Ma L,Cho SY,Kong Y

更新日期：2005-12-01 00:00:00

abstract：:Electrophysiological and pharmacological techniques were used to study glutamatergic signalling in the parasitic nematode, Ascaris suum. Glutamate or kainate injections into whole worms produced a paralysed quasi-static posture similar to the waveform in behaving worms. The DE2 motorneuron class is a primary target. S...

journal_title：Parasitology

authors： Davis RE

更新日期：1998-05-01 00:00:00

abstract：:The transmission from one host to another constitutes a challenging obstacle for parasites and is a key determinant of their fitness. Due to their complex life histories involving several different hosts, the free-living dispersal stages (cercariae) of digenean trematodes show a huge diversity in morphology and behavi...

journal_title：Parasitology

authors： Selbach C,Poulin R

更新日期：2018-09-01 00:00:00

abstract：:The objectives of this study were (a) to evaluate the sensitivity and specificity of foetal Doppler indices for the prediction of abnormal foetal heart rate (aFHR) at delivery after malaria crisis and (b) to test Doppler parameters against crisis duration for predicting aFHR. Every day during the malaria crisis, the u...

journal_title：Parasitology

authors： Arbeille P,Carles G,Georgescu M,Tobal N,Herault S,Bousquet F,Perrotin F

更新日期：2003-06-01 00:00:00

abstract：:Many clinically useful antibacterial drugs have intracellular target sites. Therefore, in order to reach their targets, these compounds must be able to cross bacterial outer and cytoplasmic membranes. Considerable information is available on the mechanisms by which antibiotics cross bacterial membranes and, in many ca...

journal_title：Parasitology

authors： Chopra I

更新日期：1988-01-01 00:00:00

abstract：:Parasites have a major impact on global finfish and shellfish aquaculture, having significant effects on farm production, sustainability and economic viability. Parasite infections and impacts can, according to pathogen and context, be considered to be either unpredictable/sporadic or predictable/regular. Although bot...

journal_title：Parasitology

authors： Shinn AP,Pratoomyot J,Bron JE,Paladini G,Brooker EE,Brooker AJ

更新日期：2015-01-01 00:00:00