Repeated infection of cats with Brugia pahangi: parasitological observations.

Abstract:

:Cats were repeatedly inoculated with infective larvae of Brugia pahangi. On parasitological grounds they could be divided into 5 groups. Group I--most cats (some 70%) became microfilaraemic (mf+) and retained high levels of microfilariae (mf) in their blood for over 2 years. In some Group I cats mf counts stabilized at high levels whilst in others mf counts continued to increase. Large numbers of fecund adult worms were recovered from their lymphatics. Adult counts were not made on the cats in the current experiments but over 100 adults have been recovered from 'super-susceptible' cats. Large amounts of B. pahangi adult antigen were consistently present in the serum of all Group I cats. About 30% of cats became amicrofilaraemic (mf-). In these cats the peak mf levels were seldom above 10,000 mf/ml. Group II--these cats had less than 10,000 mf/ml and low antigen levels. After more than 1 year of being repeatedly infected B. pahangi adult antigen slowly declined and eventually could no longer be detected in their serum and the number of mf declined very slowly after the fall in antigen levels. This shows that in Group II cats the adult worms die and as the cats are resistant to the development of the continuing weekly inoculation of L3 no new adults can develop. Group III--these cats became mf--during the first year of infection but remained B. pahangi antigen-positive for many weeks after this and, at autopsy, had living adults in their lymphatics.(ABSTRACT TRUNCATED AT 250 WORDS)

journal_name

Parasitology

journal_title

Parasitology

authors

Denham DA,Medeiros F,Baldwin C,Kumar H,Midwinter IC,Birch DW,Smail A

doi

10.1017/s0031182000063666

subject

Has Abstract

pub_date

1992-06-01 00:00:00

pages

415-20

eissn

0031-1820

issn

1469-8161

journal_volume

104 ( Pt 3)

pub_type

杂志文章
  • Comparative efficacy of immunization with inactivated whole tachyzoites versus a tachyzoite-bradyzoite mixture against neosporosis in mice.

    abstract::The worldwide economic impact of Neospora caninum infection has caused the development of effective vaccines to become one of the main goals in the field of neosporosis research. In this study, the protection conferred by antigens from inactivated whole tachyzoites (TZ) and a tachyzoite-bradyzoite mixture (TZ-BZ) of N...

    journal_title:Parasitology

    pub_type: 杂志文章

    doi:10.1017/S0031182011001156

    authors: Rojo-Montejo S,Collantes-Fernández E,Rodríguez-Marcos S,Pérez-Zaballos F,López-Pérez I,Prenafeta A,Ortega-Mora LM

    更新日期:2011-09-01 00:00:00

  • Purification of an agglutinin from the haemolymph of the snail Bulinus nasutus and demonstration of related proteins in other Bulinus spp.

    abstract::The snail Bulinus nasutus 1214 possesses a potent haemagglutinin (end-point titre with human erythrocytes, 2(-18)) in its cell-free haemolymph which also binds to the miracidia (but not other larvae) of the incompatible parasite Schistosoma margrebowiei. We have purified a protein possessing this haemagglutinating pro...

    journal_title:Parasitology

    pub_type: 杂志文章

    doi:10.1017/s0031182000074928

    authors: Harris RA,Preston TM,Southgate VR

    更新日期:1993-02-01 00:00:00

  • Purification of a 64 kDa antigen from Trypanosoma evansi that exhibits cross-reactivity with Trypanosoma vivax.

    abstract::Trypanosoma evansi and Trypanosoma vivax are the most extensively distributed trypanosomes responsible for diseases in livestock. Western blot and indirect immunofluorescence assays revealed a high immunological cross-reaction between these two parasites. An antigen with an apparent molecular mass of 64 kDa (p64), whi...

    journal_title:Parasitology

    pub_type: 杂志文章

    doi:10.1017/s0031182001001214

    authors: Uzcanga G,Mendoza M,Aso PM,Bubis J

    更新日期:2002-03-01 00:00:00

  • The relationship of Hammondia hammondi and Sarcocystis mucosa to other heteroxenous cyst-forming coccidia as inferred by phylogenetic analysis of the 18S SSU ribosomal DNA sequence.

    abstract::The complete sequence of the 18S small subunit (SSU) ribosomal DNA of Hammondia hammondi and Sarcocystis mucosa was obtained and compared to SSU rDNA sequences of Neospora caninum, Toxoplasma gondii, Besnoitia besnoiti, 2 species of Frenkelia, 3 species of Isospora, and 13 species of Sarcocystis. Analyses showed that ...

    journal_title:Parasitology

    pub_type: 杂志文章

    doi:10.1017/s0031182099004618

    authors: Jenkins MC,Ellis JT,Liddell S,Ryce C,Munday BL,Morrison DA,Dubey JP

    更新日期:1999-08-01 00:00:00

  • Plasmodium vivax Duffy binding protein: a modular evolutionary proposal.

    abstract::The population of malaria-causing parasites is characterized by great genetic diversity. Knowledge of the polymorphism generation mechanism is a central issue for developing effective vaccines against malaria and understanding the parasite population structure. Plasmodium vivax genetic diversity has been explained in ...

    journal_title:Parasitology

    pub_type: 杂志文章

    doi:10.1017/s0031182003004773

    authors: Martinez P,Suarez CF,Cardenas PP,Patarroyo MA

    更新日期:2004-04-01 00:00:00

  • Species delimitation in trematodes using DNA sequences: Middle-American Clinostomum as a case study.

    abstract::The recent development of genetic methods allows the delineation of species boundaries, especially in organisms where morphological characters are not reliable to differentiate species. However, few empirical studies have used these tools to delineate species among parasitic metazoans. Here we investigate the species ...

    journal_title:Parasitology

    pub_type: 杂志文章

    doi:10.1017/S0031182016001517

    authors: Pérez-Ponce DE León G,García-Varela M,Pinacho-Pinacho CD,Sereno-Uribe AL,Poulin R

    更新日期:2016-11-01 00:00:00

  • One hundred years of neglect in paediatric schistosomiasis.

    abstract::Early in the history of schistosomiasis research, children under 5 years of age were known to be infected. Although this problem was recognized over 100 years ago, insufficient action has been taken to address this issue. Under current policy, such infected children only receive their first antiparasitic treatment (pr...

    journal_title:Parasitology

    pub_type: 历史文章,杂志文章,评审

    doi:10.1017/S0031182017000014

    authors: Bustinduy AL,Wright S,Joekes EC,Kabatereine NB,Reinhard-Rupp J,King CH,Stothard JR

    更新日期:2017-10-01 00:00:00

  • Field evaluation of a dot-ELISA for the detection and differentiation of trypanosome species in infected tsetse flies (Glossina spp.).

    abstract::A rapid, visually read, dot-ELISA developed for the detection and differentiation of trypanosome species in tsetse flies (Glossina spp.), was field tested alongside the standard fly dissection method on a range in south eastern Kenya. Of 104 G. pallidipes dissected, 2 were found to be infected with trypanosomes in the...

    journal_title:Parasitology

    pub_type: 杂志文章

    doi:10.1017/s0031182000084778

    authors: Bosompem KM,Masake RA,Assoku RK,Opiyo EA,Nantulya VM

    更新日期:1996-02-01 00:00:00

  • Five types of nuclei present in the capsule of Trichinella spiralis.

    abstract::This study describes morphological changes during capsule formation of Trichinella spiralis with emphasis on nuclei within the capsule. The nuclei of the pre-existing muscle cell may become hypertrophied or degrade soon after the entrance of newborn larvae. Cytoplasm associated with these hypertrophied nuclei was baso...

    journal_title:Parasitology

    pub_type: 杂志文章

    doi:10.1017/s0031182099006198

    authors: Matsuo A,Wu Z,Nagano I,Takahashi Y

    更新日期:2000-08-01 00:00:00

  • Time of treatment influences the appearance of drug-resistant parasites in Plasmodium falciparum infections.

    abstract::A deterministic mathematical model which predicts the probability of developing a new drug-resistant parasite population within the human host is reported. The model incorporates the host's specific antibody response to PfEMP1, and also investigates the influence of chemotherapy on the probability of developing a viab...

    journal_title:Parasitology

    pub_type: 杂志文章

    doi:10.1017/s0031182001008824

    authors: Gatton ML,Hogarth W,Saul A

    更新日期:2001-12-01 00:00:00

  • Temperature-related parasite infection dynamics: the case of proliferative kidney disease of brown trout.

    abstract::Climate change, in particular rising temperature, is suspected to be a major driver for the emergence of many wildlife diseases. Proliferative kidney disease of salmonids, caused by the myxozoan Tetracapsuloides bryosalmonae, was used to evaluate how temperature dependence of host-parasite interactions modulates disea...

    journal_title:Parasitology

    pub_type: 杂志文章

    doi:10.1017/S0031182017001482

    authors: Strepparava N,Segner H,Ros A,Hartikainen H,Schmidt-Posthaus H,Wahli T

    更新日期:2018-03-01 00:00:00

  • The emergence of macrocyclic lactone resistance in the canine heartworm, Dirofilaria immitis.

    abstract::Prevention of heartworm disease caused by Dirofilaria immitis in domestic dogs and cats relies on a single drug class, the macrocyclic lactones (MLs). Recently, it has been demonstrated that ML-resistant D. immitis are circulating in the Mississippi Delta region of the USA, but the prevalence and impact of these resis...

    journal_title:Parasitology

    pub_type: 杂志文章,评审

    doi:10.1017/S003118201500061X

    authors: Wolstenholme AJ,Evans CC,Jimenez PD,Moorhead AR

    更新日期:2015-09-01 00:00:00

  • Rat-dietary fructose and the intestinal distribution and growth of Moniliformis (Acanthocephala).

    abstract::The numbers, distribution in the small intestine, sexual development and growth (dry weight) of 5-week-old Moniliformis dubius (Acanthocephala) were investigated experimentally in adult, female CFHB rats fed on theoretically isoenergetic diets containing known amounts of fructose in combination with either maize-oil f...

    journal_title:Parasitology

    pub_type: 杂志文章

    doi:10.1017/s0031182000057176

    authors: Crompton DW,Keymer A,Singhvi A,Nesheim MC

    更新日期:1983-02-01 00:00:00

  • The schistosome in the mammalian host: understanding the mechanisms of adaptation.

    abstract::In this review, we envisage the host environment, not as a hostile one, since the schistosome thrives there, but as one in which the relationship between the two organisms consists of constant communication, through signalling mechanisms involving sense organs, surface glycocalyx, surface membrane and internal organs ...

    journal_title:Parasitology

    pub_type: 杂志文章,评审

    doi:10.1017/S0031182007002971

    authors: Kusel JR,Al-Adhami BH,Doenhoff MJ

    更新日期:2007-10-01 00:00:00

  • Immune responses during cutaneous and visceral leishmaniasis.

    abstract::SUMMARY Leishmania are protozoan parasites spread by a sandfly insect vector and causing a spectrum of diseases collectively known as leishmaniasis. The disease is a significant health problem in many parts of the world, resulting in an estimated 1·3 million new cases and 30 000 deaths annually. Current treatment is b...

    journal_title:Parasitology

    pub_type: 杂志文章

    doi:10.1017/S003118201400095X

    authors: Kedzierski L,Evans KJ

    更新日期:2014-07-30 00:00:00

  • Maltose utilization by extracellular hydrolysis followed by glucose transport in Trichomonas vaginalis.

    abstract::The amitochondriate parasitic protist Trichomonas vaginalis can utilize either glucose or maltose as carbon and energy source. The mechanisms of maltose utilization were explored with uptake experiments using radio-isotope labelled maltose in combination with the silicone-oil centrifugation technique and enzymatic ass...

    journal_title:Parasitology

    pub_type: 杂志文章

    doi:10.1017/s0031182000081026

    authors: ter Kuile BH,Müller M

    更新日期:1995-01-01 00:00:00

  • Factors affecting surface changes in intact cercariae and cercarial bodies of Schistosoma mansoni.

    abstract::The effect of different incubation media and of temperature on the induction of water sensitivity has been investigated in intact and tailless Schistosoma mansoni cercariae. Removal of the cercarial tail by vortex stirring and elevation of the temperature of the medium from 27 to 37 degrees C resulted in the rapid ons...

    journal_title:Parasitology

    pub_type: 杂志文章

    doi:10.1017/s0031182000053105

    authors: Ramalho-Pinto FJ,Gazzinelli G,Howells RE,Pellegrino J

    更新日期:1975-08-01 00:00:00

  • Carbohydrate inhibition of Biomphalaria glabrata embryonic (Bge) cell adhesion to primary sporocysts of Schistosoma mansoni.

    abstract::Due to shared characteristics with snail haemocytes, the Biomphalaria glabrata embryonic (Bge) cell line has been used as a model in vitro system for the study of snail-trematode interactions. In this study, Bge cells were used to characterize the adherence of snail host cells to schistosome primary sporocysts, and to...

    journal_title:Parasitology

    pub_type: 杂志文章

    doi:

    authors: Castillo MG,Yoshino TP

    更新日期:2002-12-01 00:00:00

  • The attachment of Schistosoma mansoni cercariae to human skin cells.

    abstract::Most of our knowledge about the process of penetration of skin, by cercariae of Schistosoma mansoni, has been gained from studies carried out in vivo with laboratory animals. Human skin is significantly different from that of other animals but there are obvious practical difficulties in directly studying attachment an...

    journal_title:Parasitology

    pub_type: 杂志文章

    doi:10.1017/s003118200100885x

    authors: Khammo N,Bartlett A,Clothier RH,Whitfield PJ

    更新日期:2002-01-01 00:00:00

  • Cytogenetic and sequence comparison of adult Phyllodistomum (Digenea: Gorgoderidae) from the three-spined stickleback with larvae from two bivalves.

    abstract::Due to the low informative value of available morphological characters, cytogenetic and molecular methods, based on rDNA sequencing, were used to characterize adult and larval stages of Phyllodistomum spp. Species studied have 18 chromosomes with comparable absolute and relative lengths. Conventional Giemsa staining a...

    journal_title:Parasitology

    pub_type: 杂志文章

    doi:10.1017/s0031182004006109

    authors: Petkeviciŭte R,Stunzenas V,Staneviciŭte G

    更新日期:2004-12-01 00:00:00

  • Phylogenetic taxonomy of Leishmania (Viannia) braziliensis based on isoenzymatic study of 137 isolates.

    abstract::Biochemical characterization of 137 Leishmania braziliensis isolates from South and Central America, and from selected endemic foci in Bolivia, Brazil and Colombia, performed by isoenzymatic electrophoresis using 10 enzymatic systems, showed a high enzymatic polymorphism (44 zymodemes obtained) based on the variation ...

    journal_title:Parasitology

    pub_type: 杂志文章

    doi:10.1017/s0031182097001376

    authors: Chouicha N,Lanotte G,Pratlong F,Cuba Cuba CA,Velez ID,Dedet JP

    更新日期:1997-10-01 00:00:00

  • Comparison of the structures of natural and re-established populations of Ascaris in humans in a rural community of Jiangxi, China.

    abstract::To compare the structures of natural and re-established populations of Ascaris in humans, universal (mass) chemotherapy was carried out at the beginning and the end of the study year using pyrantel pamoate. Worms expelled within 48 h of treatment were collected, their sex determined, and measurements made of length, w...

    journal_title:Parasitology

    pub_type: 杂志文章

    doi:10.1017/s0031182002001737

    authors: Peng W,Cui X,Zhou X

    更新日期:2002-06-01 00:00:00

  • Molecular cloning and characterization of Echinostoma caproni heat shock protein-70 and differential expression in the parasite derived from low- and high-compatible hosts.

    abstract::We cloned and expressed Echinostoma caproni HSP70 in Escherichia coli. This molecule presents an open reading frame (ORF) of 655 amino acids, and a theoretical molecular weight of 71 kDa. E. caproni HSP70 protein showed a high homology to other helminth molecules, major differences being located in the C-terminal regi...

    journal_title:Parasitology

    pub_type: 杂志文章

    doi:10.1017/S0031182008004927

    authors: Higón M,Monteagudo C,Fried B,Esteban JG,Toledo R,Marcilla A

    更新日期:2008-10-01 00:00:00

  • Expression of LPG and GP63 by different developmental stages of Leishmania major in the sandfly Phlebotomus papatasi.

    abstract::Development and forward migration of Leishmania parasites in the sandfly gut is accompanied by morphological transformation to highly motile, non-dividing 'metacyclic' forms. Previous studies in vitro have demonstrated that this metacyclogenesis is associated with developmentally regulated changes in expression of two...

    journal_title:Parasitology

    pub_type: 杂志文章

    doi:10.1017/s0031182000060522

    authors: Davies CR,Cooper AM,Peacock C,Lane RP,Blackwell JM

    更新日期:1990-12-01 00:00:00

  • Molecular identification of Taenia spp. in the Eurasian lynx (Lynx lynx) from Finland.

    abstract::Cestodes of the genus Taenia are parasites of mammals, with mainly carnivores as definitive and herbivores as intermediate hosts. Various medium-sized cats, Lynx spp., are involved in the life cycles of several species of Taenia. The aim of the present study was to identify Taenia tapeworms in the Eurasian lynx (Lynx ...

    journal_title:Parasitology

    pub_type: 杂志文章

    doi:10.1017/S0031182012002120

    authors: Lavikainen A,Haukisalmi V,Deksne G,Holmala K,Lejeune M,Isomursu M,Jokelainen P,Näreaho A,Laakkonen J,Hoberg EP,Sukura A

    更新日期:2013-04-01 00:00:00

  • Signatures of mito-nuclear discordance in Schistosoma turkestanicum indicate a complex evolutionary history of emergence in Europe.

    abstract::High levels of molecular diversity were identified in mitochondrial cytochrome c oxidase (cox1) gene sequences of Schistosoma turkestanicum from Hungary. These cox1 sequences were all specific to Hungary which contrasted with the low levels of diversity seen in the nuclear internal transcribed spacer region (ITS) sequ...

    journal_title:Parasitology

    pub_type: 杂志文章

    doi:10.1017/S0031182017000920

    authors: Lawton SP,Bowen LI,Emery AM,Majoros G

    更新日期:2017-11-01 00:00:00

  • The alteration in signal transduction parameters induced by the excretory-secretory product from Giardia lamblia.

    abstract::The mechanism by which Giardia lamblia exerts its pathogenicity is likely to be multifactorial. A 58 kDa enterotoxin was purified and characterized from the excretory-secretory product (ESP) of the parasite (Kaur et al. 2001). In the present study an attempt has been made to elucidate the mechanism of action of the ES...

    journal_title:Parasitology

    pub_type: 杂志文章

    doi:10.1017/s0031182004005852

    authors: Shant J,Ghosh S,Bhattacharyya S,Ganguly NK,Majumdar S

    更新日期:2004-10-01 00:00:00

  • Molecular phylogenetic and morphological analysis of haemosporidian parasites (Haemosporida) in a naturally infected European songbird, the blackcap Sylvia atricapilla, with description of Haemoproteus pallidulus sp. nov.

    abstract::The blackcap (Sylvia atricapilla) is a common Palearctic migratory warbler, and haemosporidian parasites are common in this species. However, genetic and phenotypic diversity of haemosporidians in warblers has been insufficiently investigated and poorly linked. We addressed this issue by combining molecular and micros...

    journal_title:Parasitology

    pub_type: 杂志文章

    doi:10.1017/S0031182009991235

    authors: Krizanauskiene A,Pérez-Tris J,Palinauskas V,Hellgren O,Bensch S,Valkiūnas G

    更新日期:2010-02-01 00:00:00

  • Purification and characterization of a saccharide-binding protein from penetration glands of Diplostomum pseudospathaceum--a bifunctional molecule with cysteine protease activity.

    abstract::A beta-1,3-glucan-binding lectin from the penetration glands of Diplostomum pseudospathaceum cercariae was isolated by affinity chromatography using yeast glucan and curdlan as affinity matrices. Further purification to homogeneity was performed by cation-exchange chromatography. The protein migrated as a double band ...

    journal_title:Parasitology

    pub_type: 杂志文章

    doi:10.1017/s0031182003003305

    authors: Mikes L,Man P

    更新日期:2003-07-01 00:00:00

  • Density-dependent processes in the transmission of human onchocerciasis: intensity of microfilariae in the skin and their uptake by the simuliid host.

    abstract::The transmission success of Onchocerca volvulus is thought to be influenced by a variety of regulatory or density-dependent processes that act at various points in the two-host life-cycle. This paper examines one component of the life-cycle, namely, the ingestion of microfilariae by the simuliid vector, to assess the ...

    journal_title:Parasitology

    pub_type: 杂志文章

    doi:10.1017/s0031182000078586

    authors: Basáñez MG,Boussinesq M,Prod'hon J,Frontado H,Villamizar NJ,Medley GF,Anderson RM

    更新日期:1994-01-01 00:00:00