Abstract:
:In this review, we envisage the host environment, not as a hostile one, since the schistosome thrives there, but as one in which the relationship between the two organisms consists of constant communication, through signalling mechanisms involving sense organs, surface glycocalyx, surface membrane and internal organs of the parasite, with host fluids and cells. The surface and secretions of the schistosome egg have very different properties from those of other parasite stages, but adapted for the dispersal of the eggs and for the preservation of host liver function. We draw from studies of mammalian cells and other organisms to indicate how further work might be carried out on the signalling function of the surface glycocalyx, the raft structure of the surface and existence of pores in the surface membrane, the repair of the surface membrane, the role of the membrane structure in ion channel function (including recent work on the actin cytoskeleton and calcium channels) and the possible role of P-glycoproteins in the adaptation of the parasite to its environment. We are speculative in some areas, such as the suggestions that variability in surface properties of schistosomes may relate to the existence of membrane rafts and that parasite communities may exhibit quorum sensing. This speculative approach is adopted with the hope that future work on the whole organisms and their interactions will be encouraged.
journal_name
Parasitologyjournal_title
Parasitologyauthors
Kusel JR,Al-Adhami BH,Doenhoff MJdoi
10.1017/S0031182007002971subject
Has Abstractpub_date
2007-10-01 00:00:00pages
1477-526issue
Pt 11eissn
0031-1820issn
1469-8161pii
S0031182007002971journal_volume
134pub_type
杂志文章,评审相关文献
PARASITOLOGY文献大全abstract::Common bird species were screened during May and June 2007 on Barbados for haemosporidian parasites (Haemosporida) of the genera Haemoproteus and Plasmodium to determine whether the low parasite diversity reported in previous studies might have reflected limited sampling. PCR screening and DNA sequencing revealed a si...
journal_title:Parasitology
pub_type: 杂志文章
doi:10.1017/S0031182009990497
更新日期:2009-09-01 00:00:00
abstract::Receptors interacting with terminal sugars as ligands are involved in the binding of Leishmania donovani promastigotes to the macrophage surface and their subsequent internalization. Mannose and glucose are specifically involved in the binding process. Decreased binding occurs to macrophages already infected with L. d...
journal_title:Parasitology
pub_type: 杂志文章
doi:10.1017/s0031182000076253
更新日期:1994-08-01 00:00:00
abstract::Philasterides dicentrarchi is a histophagous ciliate causing systemic scuticociliatosis in cultured turbot. This study demonstrates that turbot which survive this disease have serum antibodies that recognize ciliary antigens of this ciliate in ELISA and immobilize/agglutinate the ciliate in vitro. Mouse sera raised ag...
journal_title:Parasitology
pub_type: 杂志文章
doi:10.1017/s0031182002002688
更新日期:2003-02-01 00:00:00
abstract::Patterns of genetic subdivision in parasite populations can provide important insights into transmission processes and complement information obtained using traditional epidemiological techniques. We describe mitochondrial sequence variation in 265 Ascaris collected from 62 individual hosts (humans and pigs) from 35 h...
journal_title:Parasitology
pub_type: 杂志文章
doi:10.1017/s003118200006399x
更新日期:1995-02-01 00:00:00
abstract::Changes during development in the elemental contents (Ca, P, K, Mg and S) of male and female Schistosoma mansoni from both mixed and single sex infections have been measured for the first time. In mixed infections, there is a significant difference between the calcium content of male and female worms; female worms hav...
journal_title:Parasitology
pub_type: 杂志文章
doi:10.1017/s0031182000050630
更新日期:1983-06-01 00:00:00
abstract::Small vessels showing inflammatory cell infiltrates were invariably observed in the vicinity of intact Toxoplasma tissue cysts within the brains of mice congenitally infected with the protozoan. Lymphocytes were observed in intimate contact with the luminal aspect of the endothelium, penetrating into the thickened bas...
journal_title:Parasitology
pub_type: 杂志文章
doi:10.1017/s0031182000063873
更新日期:1995-02-01 00:00:00
abstract::Ascarid parasites infect a variety of hosts and regular anthelmintic treatment is recommended for all species. Parascaris spp. is the only ascarid species with widespread anthelmintic resistance, which allows for the study of resistance mechanisms. The purpose of this study was to establish an in vitro drug exposure p...
journal_title:Parasitology
pub_type: 杂志文章
doi:10.1017/S0031182020000189
更新日期:2020-05-01 00:00:00
abstract::We examine the evolution of microparasites in response to the immune system of vertebrate hosts. We first describe a simple model for an acute infection. This model suggests that the within-host dynamics of the microparasite will be a 'race' between parasite multiplication and a clonally expanding response by the host...
journal_title:Parasitology
pub_type: 杂志文章,评审
doi:10.1017/s003118209700200x
更新日期:1997-01-01 00:00:00
abstract::Host location by parasites can be achieved by either active or passive mechanisms. In spite of their significance, the efficacy of these methods has been little researched. High fecundity in parasites is discussed in terms of the role it plays in dispersal and transmission. Some concepts developed by mainstream behavi...
journal_title:Parasitology
pub_type: 杂志文章,评审
doi:10.1017/s0031182000085061
更新日期:1994-01-01 00:00:00
abstract::The acanthocephalan parasite, Polymorphus minutus, manipulates its intermediate hosts' (gammarids) behaviour, presumably to facilitate its transmission to the definitive hosts. A fundamental question is whether this capability has evolved to target gammarids in general, or specifically sympatric gammarids. We assessed...
journal_title:Parasitology
pub_type: 杂志文章
doi:10.1017/S0031182020002140
更新日期:2020-11-13 00:00:00
abstract::The ultrastructure of the formation of the first-stage cuticle within the egg of Trichostrongylus colubriformis is described. The first indication of cuticle formation was the formation of the epicuticle external to the epidermal plasma membrane. This becomes thickened to form the epicuticle of the fully formed cuticl...
journal_title:Parasitology
pub_type: 杂志文章
doi:10.1017/s0031182000058868
更新日期:1988-12-01 00:00:00
abstract::Life-cycle stages of the microsporidia Nosema bombycis, the pathogen causing silkworm pebrine, were separated and purified by an improved method of Percoll-gradient centrifugation. Soluble protein fractions of late sporoblasts (spore precursor cells) and mature spores were analysed by two-dimensional polyacrylamide ge...
journal_title:Parasitology
pub_type: 杂志文章
doi:10.1017/S0031182011000801
更新日期:2011-08-01 00:00:00
abstract::In the context of a broader program dealing with the symbiotic associations of apple snails, we sampled three species that coexist in Lake Regatas (Palermo, Buenos Aires, Argentina). The population of Asolene platae, (but not those of Pomacea canaliculata and Pomacea scalaris) showed trematode larvae (echinocercariae ...
journal_title:Parasitology
pub_type: 杂志文章
doi:10.1017/S0031182019000027
更新日期:2019-06-01 00:00:00
abstract::Avian malaria is a mosquito-borne disease caused by Plasmodium spp. protozoa. Although these parasites have been extensively studied in North America and Eurasia, knowledge on the diversity of Plasmodium, its vectors and avian hosts in Africa is scarce. In this study, we report on natural malarial infections in free-r...
journal_title:Parasitology
pub_type: 杂志文章
doi:10.1017/S0031182020000566
更新日期:2020-08-01 00:00:00
abstract::Conventional mice and congenitally athymic, nude mice were infected with 20 metacercariae of the intestinal trematode Echinostoma revolutum. The sequential events in the pathological changes in the intestine were studied at different intervals post-infection. By day 11 onwards the conventional mice displayed dilatatio...
journal_title:Parasitology
pub_type: 杂志文章
doi:10.1017/s0031182000054706
更新日期:1984-06-01 00:00:00
abstract::The group of haemosporidian parasites is of general interest to basic and applied science, since several species infect mammals, leading to malaria and associated disease symptoms. Although the great majority of haemosporidian parasites appear in bird hosts, as in the case of Leucocytozoon buteonis, there is little ge...
journal_title:Parasitology
pub_type: 杂志文章
doi:10.1017/S0031182012000972
更新日期:2012-10-01 00:00:00
abstract::With the increased availability of multilocus sequence data, the lack of concordance of gene trees estimated for independent loci has focused attention on both the biological processes producing the discord and the methodologies used to estimate phylogenetic relationships. What has emerged is a suite of new analytical...
journal_title:Parasitology
pub_type: 杂志文章
doi:10.1017/S003118201100031X
更新日期:2011-11-01 00:00:00
abstract::An apparatus for artificial feeding of Rhipicephalus appendiculatus nymphae was modified to improve feeding performance. Heparinized blood was supplied above a treated artificial membrane while the ticks attached below on its undersurface. The feeding apparatus was incubated at 37 degrees C in an atmosphere of 3% CO2 ...
journal_title:Parasitology
pub_type: 杂志文章
doi:10.1017/s0031182000065963
更新日期:1995-11-01 00:00:00
abstract::Quinine (QN) and quinidine (QND) have been commonly used as effective and affordable antimalarials for over many years. Quinine primarily is used for severe malaria treatment. However, plasmodia resistance to these drugs and poor patient compliance limits their administration to the patients. The declining sensitivity...
journal_title:Parasitology
pub_type: 杂志文章
doi:10.1017/S003118201200176X
更新日期:2013-03-01 00:00:00
abstract::Plant cysteine proteinases (CPs) from Carica papaya kill parasitic and free-living nematodes in vitro by hydrolysis of the worm cuticle, a mechanism that is different to all commercially available synthetic anthelmintics. We have developed a cheap and effective, rapid-throughput Caenorhabditis elegans-based assay for ...
journal_title:Parasitology
pub_type: 杂志文章
doi:10.1017/S0031182016002353
更新日期:2017-04-01 00:00:00
abstract::Vitellogenin synthesis by the fat body has been monitored using in vitro culture and immunoprecipitation. This system was found to be efficient for measuring vitellogenin production in both non-infected Tenebrio molitor and those infected with Hymenolepis diminuta. In fat bodies from infected beetles, vitellogenin pro...
journal_title:Parasitology
pub_type: 杂志文章
doi:10.1017/s0031182000066658
更新日期:1996-04-01 00:00:00
abstract::Costa Rica is near malaria elimination. This achievement has followed shifts in malaria health policy. Here, we evaluate the impacts that different health policies have had on malaria transmission in Costa Rica from 1913 to 2018. We identified regime shifts and used regression models to measure the impact of different...
journal_title:Parasitology
pub_type: 杂志文章
doi:10.1017/S0031182020000621
更新日期:2020-08-01 00:00:00
abstract::DNA barcoding is now a common tool in parasitology and epidemiology, which require good methods for identification not only of parasites and pathogens but vectors and reservoirs. This special issue presents some advances and challenges in barcoding of microbes, parasites, and their vectors and reservoirs. DNA barcodin...
journal_title:Parasitology
pub_type: 社论
doi:10.1017/S0031182018000884
更新日期:2018-04-01 00:00:00
abstract::A prediction of the hypothesis of Wilson (1977, 1980 a, b) to account for larval migration of homogonic Strongyloides ratti in the host is that the pattern of invasion of the mammary gland of a lactating rat will be quantitatively similar on both sides and independent of the point of entry into the body. Twenty-one su...
journal_title:Parasitology
pub_type: 杂志文章
doi:10.1017/s0031182000052744
更新日期:1982-06-01 00:00:00
abstract::Treatment of BALB/c or MF1 mice with cyclosporin A (CsA) around the time of infection with Schistosoma mansoni conferred almost complete protection. The migration kinetics of L-[75Se]selenomethionine-labelled infective cercariae were investigated by compressed tissue autoradiography. Similar levels of skin penetration...
journal_title:Parasitology
pub_type: 杂志文章
doi:10.1017/s0031182000060340
更新日期:1991-02-01 00:00:00
abstract::The amitochondriate parasitic protist Trichomonas vaginalis can utilize either glucose or maltose as carbon and energy source. The mechanisms of maltose utilization were explored with uptake experiments using radio-isotope labelled maltose in combination with the silicone-oil centrifugation technique and enzymatic ass...
journal_title:Parasitology
pub_type: 杂志文章
doi:10.1017/s0031182000081026
更新日期:1995-01-01 00:00:00
abstract::The complex life-cycles of parasitic animals are a product of exploiting the process of development to generate organisms with different biological potentials within a species. Successive stages of the parasite adapt to functions such as host invasion and transmission, and to the colonization of a variety of niches, o...
journal_title:Parasitology
pub_type: 杂志文章,评审
doi:10.1017/s0031182000083451
更新日期:1989-01-01 00:00:00
abstract::In situations where malaria eradication is not an option in the foreseeable future the emphasis must be on the control of morbidity and mortality due to malaria. Under such circumstances drawing a distinction between malarial parasitization and malarial disease may be important for workers in both field and laboratory...
journal_title:Parasitology
pub_type: 杂志文章,评审
doi:10.1017/s0031182000075247
更新日期:1992-01-01 00:00:00
abstract::Fourth-stage larvae of Ascaris suum, recovered from piglets at 11-22 days post-infection (p.i.), were examined by light microscopy for changes in the somatic musculature. During this time the estimated total number of muscle cells in the body increases from approximately 600 to 21 000 cells. This non-eutelic developme...
journal_title:Parasitology
pub_type: 杂志文章
doi:10.1017/s003118200005441x
更新日期:1984-02-01 00:00:00
abstract::Recent publications demonstrated that a fragment of a Neospora caninum ROP2 family member antigen represents a promising vaccine candidate. We here report on the cloning of the cDNA encoding this protein, N. caninum ROP2 family member 1 (NcROP2Fam-1), its molecular characterization and localization. The protein posses...
journal_title:Parasitology
pub_type: 杂志文章
doi:10.1017/S0031182013000383
更新日期:2013-07-01 00:00:00