Ascarids exposed: a method for in vitro drug exposure and gene expression analysis of anthelmintic naïve Parascaris spp.

abstract：:Plants containing condensed tannins (CT) may have potential to control gastrointestinal nematodes (GIN) of cattle. The aim was to investigate the anthelmintic activities of four flavan-3-ols, two galloyl derivatives and 14 purified CT fractions, and to define which structural features of CT determine the anti-parasiti...

journal_title：Parasitology

authors： Desrues O,Fryganas C,Ropiak HM,Mueller-Harvey I,Enemark HL,Thamsborg SM

更新日期：2016-04-01 00:00:00

abstract：:In the context of a broader program dealing with the symbiotic associations of apple snails, we sampled three species that coexist in Lake Regatas (Palermo, Buenos Aires, Argentina). The population of Asolene platae, (but not those of Pomacea canaliculata and Pomacea scalaris) showed trematode larvae (echinocercariae ...

journal_title：Parasitology

authors： Dellagnola FA,Montes MM,Martorelli SR,Vega IA

更新日期：2019-06-01 00:00:00

abstract：:The biodiversity of Trypanosoma cruzi is one of the main factors complicating the understanding of its molecular epidemiology. As an alternative to classical genetic methods, investigators have used DNA-mediated transformation techniques to study this diversity. Recently, transient expression data were shown to correl...

journal_title：Parasitology

authors： Laurent JP,Swindle J

更新日期：1999-12-01 00:00:00

abstract：:A specific enzyme-linked immunosorbent assay, based on a 48 kDa metallo-proteinase isolated from the frontal glands of a porocephalid pentastomid (Porocephalus crotali) in rat intermediate hosts, is described. SDS-PAGE analysis of whole nymphal homogenate, followed by Western blotting and probing with immune rat serum...

journal_title：Parasitology

authors： Jones DA,Riley J

更新日期：1991-12-01 00:00:00

abstract：:Dr David Livingstone died on May 1st 1873. He was 60 years old and had spent much of the previous 30 years walking across large stretches of Southern Africa, exploring the terrain he hoped could provide new environments in which Europeans and Africans could cohabit on equal terms and bring prosperity to a part of the ...

journal_title：Parasitology

authors： Barrett MP,Giordani F

更新日期：2017-10-01 00:00:00

abstract：:Nitric oxide (NO) produced by cytokine-activated macrophages is reported to be cytotoxic against the helminth Schistosoma mansoni, although this is a controversial issue. Previous work in our laboratory identified a fraction of S. mansoni soluble adult worm antigenic preparation (SWAP), named PIII, able to elicit sign...

journal_title：Parasitology

authors： Oliveira DM,Silva-Teixeira DN,Gustavson S,Oliveira SM,Goes AM

更新日期：2000-04-01 00:00:00

abstract：:Stratospheric ozone depletion threatens to increase exposure to ultraviolet (UV) radiation which is known to be a factor in a number of diseases. There is little doubt that cumulative exposure to UV radiation is important in the aetiology of non-melanoma skin cancers. Evidence is also strong for a link with cutaneous ...

journal_title：Parasitology

authors： Bentham G

更新日期：1993-01-01 00:00:00

abstract：:Early in the history of schistosomiasis research, children under 5 years of age were known to be infected. Although this problem was recognized over 100 years ago, insufficient action has been taken to address this issue. Under current policy, such infected children only receive their first antiparasitic treatment (pr...

journal_title：Parasitology

authors： Bustinduy AL,Wright S,Joekes EC,Kabatereine NB,Reinhard-Rupp J,King CH,Stothard JR

更新日期：2017-10-01 00:00:00

abstract：:A molecular approach was used to genetically characterize 5 species (Aoruroides queenslandensis, Blattophila sphaerolaima, Cordonicola gibsoni, Desmicola ornata and Leidynemella fusiformis) belonging to the superfamily Thelastomatoidea (Nematoda: Oxyurida), a group of pinworms that parasitizes terrestrial arthropods. ...

journal_title：Parasitology

authors： Jex AR,Hu M,Rose HA,Schneider M,Cribb TH,Gasser RB

更新日期：2006-07-01 00:00:00

abstract：:The outcome of a parasite infection is the result of the interaction between the host and the parasite. In the system we studied, there are 3 critical stages for the outcome of infection of the (intermediate) host, the copepod Macrocyclops albidus, with the cestode Schistocephalus solidus. During the establishment pha...

journal_title：Parasitology

authors： van der Veen IT,Kurtz J

更新日期：2002-04-01 00:00:00

abstract：:Protozoan parasites of the genus Cryptosporidium infect all vertebrate groups and display some host specificity in their infections. It is therefore possible to assume that Cryptosporidium parasites evolved intimately aside with vertebrate lineages. Here we propose a scenario of Cryptosporidium-Vertebrata coevolution ...

journal_title：Parasitology

authors： Garcia-R JC,Hayman DT

更新日期：2016-11-01 00:00:00

abstract：:The epidemiological and ecological processes which govern the success of multiple-species co-infections are as yet unresolved. Here we investigated prior versus late residency within hosts, meaning which parasite contacts the host first, to determine if the outcomes of intra-host competition are altered. We infected a...

journal_title：Parasitology

authors： Lohr JN,Yin M,Wolinska J

更新日期：2010-09-01 00:00:00

abstract：:Protective immunity against larval Taenia crassiceps has been shown to rely on T cells; however, the roles of the specific subsets of T cells during infection are not known. To investigate a possible role for gamma delta T cells, this study investigated larval infection in delta-chain knock-out C57BL/6 (deltaKO) and w...

journal_title：Parasitology

authors： Toenjes SA,Spolski RJ,Mooney KA,Kuhn RE

更新日期：1999-10-01 00:00:00

abstract：:Since 2004 there has been a remarkable increment in our knowledge of the proteins and glycans that reside at, or are released from the surfaces of schistosomes in the mammalian host. Initial characterization of the soluble proteome permits distinctions to be made between the parasite secretome and its necrotome. The p...

journal_title：Parasitology

authors： Wilson RA

更新日期：2012-08-01 00:00:00

abstract：:In this study, we describe the molecular analysis of zinc-metalloproteases from the abomasal nematode Ostertagia ostertagi which were exclusively recognized by local antibodies of immune cattle. Full-length or partial coding sequences of 4 different zinc-metalloprotease cDNAs of Ostertagia (met-1, -2, -3 and -4) were ...

journal_title：Parasitology

authors： De Maere V,Vercauteren I,Geldhof P,Gevaert K,Vercruysse J,Claerebout E

更新日期：2005-01-01 00:00:00

abstract：:Neospora caninum is an Apicomplexan protozoan that has the dog as a definitive host and cattle (among other animals) as intermediate hosts. It causes encephalopathy in dogs and abortion in cows, with significant loss in worldwide livestock. As any Apicomplexan, the parasite invades the cells using proteins contained i...

journal_title：Parasitology

authors： Pereira LM,Candido-Silva JA,De Vries E,Yatsuda AP

更新日期：2011-03-01 00:00:00

abstract：:The parasitic roundworms Strongyloides stercoralis (in man) and Strongyloides ratti (in rats) employ environmentally controlled XX/XO sex determination with a pair of X chromosomes and two pairs of autosomes. Strongyloides papillosus (in sheep) has only two pairs of chromosomes, one of which combines the genetic mater...

journal_title：Parasitology

authors： Kulkarni A,Dyka A,Nemetschke L,Grant WN,Streit A

更新日期：2013-12-01 00:00:00

abstract：:Longitudinal muscles in adult male Schistosoma mansoni appear to remain in almost all respects functional after tegumental disruption by Triton X-100. Responses to high K+, ouabain, low temperature, praziquantel and neurotransmitters are still present. Muscle membrane potentials remain near those of control animals an...

journal_title：Parasitology

authors： Depenbusch JW,Thompson DP,Pax RA,Bennett JL

更新日期：1983-08-01 00:00:00

abstract：:In recent years, a malaria infection of humans in South East Asia, originally diagnosed as a known human-infecting species, Plasmodium malariae, has been identified as a simian parasite, Plasmodium knowlesi. This species had been subject to considerable investigation in monkeys since the 1930s. With the development of...

journal_title：Parasitology

authors： Butcher GA,Mitchell GH

更新日期：2018-01-01 00:00:00

abstract：:Schizont-infected red blood cells (SI-RBC) from Plasmodium berghei-infected mice contain between 2 and 10 times as much sialic acid as uninfected RBC from the same blood (99-550 micrograms/10(10) RBC versus 33-65 micrograms/10(10) RBC). Total RBC samples from infected animals containing up to 63% ring- and trophozoite...

journal_title：Parasitology

authors： Howard RJ,Seeley DC Jr,Kao V,Wember M,Schauer R

更新日期：1986-06-01 00:00:00

abstract：:The pentastomid parasite, Raillietiella frenata, is native to Asia where it infects the Asian House gecko, Hemidactylus frenatus. This gecko has been widely introduced and recently R. frenata was found in introduced populations of cane toads (Rhinella marina) in Australia, indicating a host-switch from introduced geck...

journal_title：Parasitology

authors： Kelehear C,Saltonstall K,Torchin ME

更新日期：2015-04-01 00:00:00

abstract：:The nematode-trapping fungus Arthrobotrys oligospora traps and invades all the free-living juvenile stages of the trichostrongyle nematode Trichostrongylus colubriformis. The processes of capture and invasion of the 1st-stage juveniles are described using differential interference contrast optics and 3-D reconstructio...

journal_title：Parasitology

authors： Murray DS,Wharton DA

更新日期：1990-08-01 00:00:00

abstract：:Biochemical characterization of 137 Leishmania braziliensis isolates from South and Central America, and from selected endemic foci in Bolivia, Brazil and Colombia, performed by isoenzymatic electrophoresis using 10 enzymatic systems, showed a high enzymatic polymorphism (44 zymodemes obtained) based on the variation ...

journal_title：Parasitology

authors： Chouicha N,Lanotte G,Pratlong F,Cuba Cuba CA,Velez ID,Dedet JP

更新日期：1997-10-01 00:00:00

abstract：:Due to the low informative value of available morphological characters, cytogenetic and molecular methods, based on rDNA sequencing, were used to characterize adult and larval stages of Phyllodistomum spp. Species studied have 18 chromosomes with comparable absolute and relative lengths. Conventional Giemsa staining a...

journal_title：Parasitology

authors： Petkeviciŭte R,Stunzenas V,Staneviciŭte G

更新日期：2004-12-01 00:00:00

abstract：:Infection by larval Echinococcus granulosus is usually characterized by tight inflammatory control. However, various degrees of chronic granulomatous inflammation are also observed, reaching a high point in infection of cattle by the most prevalent parasite strain worldwide, which is not well adapted to this host spec...

journal_title：Parasitology

authors： Basika T,Muñoz N,Casaravilla C,Irigoín F,Batthyány C,Bonilla M,Salinas G,Pacheco JP,Roth J,Durán R,Díaz A

更新日期：2012-02-01 00:00:00

abstract：:Stability of trichostrogylid populations indicates that some form of density-dependent regulation occurs which could act through fecundity. We present evidence for intraspecific density-dependent effects in 1 of 2, dominant, abomasal nematodes species (Ostertagia gruehneri) of Svalbard reindeer (Rangifer tarandus plat...

journal_title：Parasitology

authors： Irvine RJ,Stien A,Dallas JF,Halvorsen,Langvatn R,Albon SD

更新日期：2001-06-01 00:00:00

abstract：:The protein composition of Schistosoma mansoni was analysed by electrophoresis in polyacrylamide slab gel in the presence of sodium dodecyl sulphate. A high degree of identity existed between protein patterns obtain from immature and adult parasites of the two sexes. Some stage-and sex-specific components were indenti...

journal_title：Parasitology

authors： Ruppel A,Cioli D

更新日期：1977-12-01 00:00:00

abstract：:A recombinant baculovirus-expressed hybrid protein containing epitopes for the C-terminal fragment of the Plasmodium falciparum precursor to the major merozoite surface antigens (PMMSA) and the tetrapeptide repeats of the circumsporozoite protein (CSP) was assessed for its immunogenicity. Murine MHC-II restriction of ...

journal_title：Parasitology

authors： Lockyer MJ,Cooper H,Tite J,Rowan W,Crowe JS

更新日期：1993-06-01 00:00:00

abstract：:Acetylcholinesterase (AChE) is present in all stages of the life-cycle of schistosomes and is located in muscle and on the surface of the parasite. Metrifonate is a drug that inhibits AChE. We compared the AChEs from three schistosome species (Schistosoma mansoni, Schistosoma haematobium and Schistosoma bovis) that ha...

journal_title：Parasitology

authors： Camacho M,Tarrab-Hazdai R,Espinoza B,Arnon R,Agnew A

更新日期：1994-02-01 00:00:00

abstract：:Experiments to investigate the metabolism of glycine, L-glutamic acid and L-aspartic acid by Moniliformis moniliformis were carried out by incubating adult worms aerobically for 3 h at 37 degrees C in Tyrode's solution containing either [U-14C]glycine, L-[U-14C]glutamic acid, L-[U-14C]aspartic acid or L-[4-14C]asparti...

journal_title：Parasitology

authors： Ward PF,Crompton DW

更新日期：1987-06-01 00:00:00