Parastrongyloides trichosuri suggests that XX/XO sex determination is ancestral in Strongyloididae (Nematoda).


:The parasitic roundworms Strongyloides stercoralis (in man) and Strongyloides ratti (in rats) employ environmentally controlled XX/XO sex determination with a pair of X chromosomes and two pairs of autosomes. Strongyloides papillosus (in sheep) has only two pairs of chromosomes, one of which combines the genetic material homologous to the S. ratti chromosomes X and I. This species creates males through the elimination of one copy of the portion related to the X chromosome (chromatin diminution). It is not clear which one of these two sex-determining mechanisms is ancestral. We demonstrate that Strongyloides vituli (in cattle) has two pairs of chromosomes like its very close relative S. papillosus whereas Parastrongyloides trichosuri, a closely related out-group to Strongyloides spp. in Australian brushtail possums, has three chromosome pairs and employs XX/XO sex determination. The X chromosome of P. trichosuri is homologous to the X chromosome of S. ratti. Our data strongly suggest that the last common ancestor of Strongyloides spp. and Parastrongyloides spp. had two pairs of autosomes along with two or one X chromosome in females and males, respectively. The situation with two pairs of chromosomes is likely derived and occurred through the fusion of the X chromosome with an autosome.






Kulkarni A,Dyka A,Nemetschke L,Grant WN,Streit A




Has Abstract


2013-12-01 00:00:00














  • Molecular evolution of freshwater snail intermediate hosts within the Bulinus forskalii group.

    abstract::Freshwater snails of the Bulinus forskalii group are one of four Bulinus species complexes responsible for the transmission of schistosomes in Africa and adjacent regions. The species status of these conchologically variable and widely distributed planorbids remains unclear, and parasite compatibility varies considera...


    pub_type: 杂志文章


    authors: Jones CS,Rollinson D,Mimpfoundi R,Ouma J,Kariuki HC,Noble LR

    更新日期:2001-01-01 00:00:00

  • Malarial parasites and antioxidant nutrients.

    abstract::Susceptibility to oxidative stress is a well-established feature of the malarial parasite. Pharmacologists have taken advantage of this property to design highly effective pro-oxidant antimalarial drugs. Less well appreciated is the fact that nutritional manipulation of host oxidative stress status by dietary means ca...


    pub_type: 杂志文章,评审


    authors: Levander OA,Ager AL Jr

    更新日期:1993-01-01 00:00:00

  • Mechanisms underlying reduced expulsion of a murine nematode infection during protein deficiency.

    abstract::Balb/c mice infected with the gastrointestinal nematode Heligmosomoides bakeri were fed protein sufficient (PS, 24%) or deficient (PD, 3%) diets to investigate whether diet, infection or dose of larval challenge (0, 100 or 200 larvae) influenced gut pathophysiology and inflammation. Among the PS mice, worms were more ...


    pub_type: 杂志文章


    authors: Tu T,Koski KG,Scott ME

    更新日期:2008-01-01 00:00:00

  • Proteomic analysis of Entamoeba histolytica.

    abstract::In this study, the proteome of axenically grown Entamoeba histolytica parasites was explored by two-dimensional gel electrophoresis (2-DE), employing a practical and effective procedure for the solubilization of E. histolytica proteins. Approximately 900 protein species in the pH range between 4 and 7 were detected by...


    pub_type: 杂志文章


    authors: Tolstrup J,Krause E,Tannich E,Bruchhaus I

    更新日期:2007-02-01 00:00:00

  • Identification and characterization of cross-reactive antigens from Neospora caninum and Toxoplasma gondii.

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    pub_type: 杂志文章


    authors: Liao M,Xuan X,Huang X,Shirafuji H,Fukumoto S,Hirata H,Suzuki H,Fujisaki K

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  • Environmental sodium regulates cutaneous sugar transport in a digenean fluke.

    abstract::Glucose uptake was examined in adult specimens of Proterometra macrostoma (Trematoda: Digenea) recovered from the stomach (endoparasites) and gills (ectoparasites) of longear sunfish, Lepomis megalotis. The endoparasitic forms transported glucose directly through the external body surface by Na+-independent, facilitat...


    pub_type: 杂志文章


    authors: Uglem GL

    更新日期:1987-02-01 00:00:00

  • Factors influencing infections in Rhipicephalus appendiculatus ticks fed on cattle infected with Theileria parva.

    abstract::A large database on the transmission of a stabilate of the Theileria parva Muguga stock from one breed of cattle using two stocks of Rhipicephalus appendiculatus, Muguga and Ol Pejeta was developed and analysed. Factors associated with the ticks and cattle, and the infections developing in cattle were studied in relat...


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    authors: Young AS,Dolan TT,Morzaria SP,Mwakima FN,Norval RA,Scott J,Sherriff A,Gettinby G

    更新日期:1996-09-01 00:00:00

  • Impaired health status and increased incidence of diseases in Toxoplasma-seropositive subjects - an explorative cross-sectional study.

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    pub_type: 杂志文章


    authors: Flegr J,Escudero DQ

    更新日期:2016-12-01 00:00:00

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    pub_type: 杂志文章,评审


    authors: Kaufman WR

    更新日期:2004-01-01 00:00:00

  • Adaptation of Cryptosporidium oocysts to different excystation conditions.

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    authors: Widmer G,Klein P,Bonilla R

    更新日期:2007-10-01 00:00:00

  • Sialic acid analysis and tritium-labelling of sialoglycoproteins of mouse erythrocytes infected with Plasmodium berghei.

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    authors: Howard RJ,Seeley DC Jr,Kao V,Wember M,Schauer R

    更新日期:1986-06-01 00:00:00

  • Increased levels of thiols protect antimony unresponsive Leishmania donovani field isolates against reactive oxygen species generated by trivalent antimony.

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    pub_type: 杂志文章


    authors: Mandal G,Wyllie S,Singh N,Sundar S,Fairlamb AH,Chatterjee M

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    pub_type: 杂志文章


    authors: Harwood CL,Young IS,Lee DL,Altringham JD

    更新日期:1996-12-01 00:00:00

  • Health policy impacts on malaria transmission in Costa Rica.

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    pub_type: 杂志文章,评审


    authors: Shinn AP,Pratoomyot J,Bron JE,Paladini G,Brooker EE,Brooker AJ

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    authors: Smith T,Maire N,Ross A,Penny M,Chitnis N,Schapira A,Studer A,Genton B,Lengeler C,Tediosi F,de Savigny D,Tanner M

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    authors: Wu Z,Nagano I,Takahashi Y

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    pub_type: 杂志文章


    authors: Walliker D,Sanderson A,Yoeli M,Hargreaves BJ

    更新日期:1976-04-01 00:00:00

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    pub_type: 杂志文章


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    pub_type: 杂志文章


    authors: Matsuo A,Wu Z,Nagano I,Takahashi Y

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    pub_type: 杂志文章


    authors: Müller N,Frei E,Nuñez S,Gottstein B

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    authors: Montes JF,Durfort M,Lladó A,García-Valero J

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    pub_type: 杂志文章


    authors: Jones DA,Riley J

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    pub_type: 杂志文章


    authors: Shirley MW,Bellatti MA,Millard BJ

    更新日期:1982-04-01 00:00:00

  • Biological approaches to characterize the mode of action of two 5-nitroindazolinone prototypes on Trypanosoma cruzi bloodstream trypomastigotes.

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    pub_type: 杂志文章


    authors: Fonseca-Berzal C,DA Silva CF,Menna-Barreto RF,Batista MM,Escario JA,Arán VJ,Gómez-Barrio A,Soeiro Mde N

    更新日期:2016-09-01 00:00:00

  • Long-term epidemiology, effect on body condition and interspecific interactions of concomitant infection by nasopharyngeal bot fly larvae (Cephenemyia auribarbis and Pharyngomyia picta, Oestridae) in a population of Iberian red deer (Cervus elaphus hispan

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    pub_type: 杂志文章


    authors: Vicente J,Fierro Y,Martínez M,Gortázar C

    更新日期:2004-09-01 00:00:00

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    pub_type: 杂志文章


    authors: Mapes CJ,Gallie GJ

    更新日期:1977-06-01 00:00:00

  • Tick-borne disease systems emerge from the shadows: the beauty lies in molecular detail, the message in epidemiology.

    abstract::This review focuses on some of the more ground-shifting advances of recent decades, particularly those at the molecular and cellular level that illuminate mechanisms underpinning the natural ecology of tick-host-pathogen interactions and the consequent epidemiology of zoonotic infections in humans. Knowledge of compon...


    pub_type: 杂志文章,评审


    authors: Randolph SE

    更新日期:2009-10-01 00:00:00

  • Evolutionary pressures in the spread and persistence of infectious agents in vertebrate populations.

    abstract::Infectious agents have considerable potential to regulate or constrain the population growth of vertebrate hosts in natural habitats. A broad theoretical framework provides many insights into how the biology of the parasite and the demography of the host interact to determine this impact. It may manifest itself as a s...


    pub_type: 杂志文章,评审


    authors: Anderson RM

    更新日期:1995-01-01 00:00:00