A comparative analysis of various developmental stages of Schistosoma mansoni with respect to their protein composition.

abstract：:We have studied the genomic organization and transcription of the histone H2A genes in the protozoan parasite Leishmania infantum. In the parasite genome 2 gene clusters exist, each containing 3 H2A gene copies. Sequence analyses showed the existence of significant sequence divergence among the H2A genes, mainly in th...

journal_title：Parasitology

authors： Soto M,Quijada L,Larreta R,Iborra S,Alonso C,Requena JM

更新日期：2003-08-01 00:00:00

abstract：:Uptake of radioactivity labelled purine bases and nucleosides by suspensions of Trypanosoma brucei and Trypanosoma congolense in bicine buffer was determined at 37 degrees C. With T. brucei, the rate of uptake of adenosine was much greater than that of the other compounds tested, the uptake of which decreased in the o...

journal_title：Parasitology

authors： James DM,Born GV

更新日期：1980-10-01 00:00:00

abstract：:This study evaluated the effectiveness of low doses of benznidazole (BNZ) on continuous administration (BNZc), combined with allopurinol (ALO), in C57BL/6J and C3H/HeN mice infected with Trypanosoma cruzi Nicaragua strain and T. cruzi Sylvio-X10/4 clone. TcN-C57BL/6J was also treated with intermittent doses of BNZ (BN...

journal_title：Parasitology

authors： Rial MS,Scalise ML,López Alarcón M,Esteva MI,Búa J,Benatar AF,Prado NG,Riarte AR,Fichera LE

更新日期：2019-03-01 00:00:00

abstract：:Protective immunity against larval Taenia crassiceps has been shown to rely on T cells; however, the roles of the specific subsets of T cells during infection are not known. To investigate a possible role for gamma delta T cells, this study investigated larval infection in delta-chain knock-out C57BL/6 (deltaKO) and w...

journal_title：Parasitology

authors： Toenjes SA,Spolski RJ,Mooney KA,Kuhn RE

更新日期：1999-10-01 00:00:00

abstract：:Recent publications demonstrated that a fragment of a Neospora caninum ROP2 family member antigen represents a promising vaccine candidate. We here report on the cloning of the cDNA encoding this protein, N. caninum ROP2 family member 1 (NcROP2Fam-1), its molecular characterization and localization. The protein posses...

journal_title：Parasitology

authors： Alaeddine F,Hemphill A,Debache K,Guionaud C

更新日期：2013-07-01 00:00:00

abstract：:We examined the mechanism of action and compared the anthelmintic efficacy of cysteine proteinases from papaya, pineapple, fig, kiwi fruit and Egyptian milkweed in vitro using the rodent gastrointestinal nematode Heligmosomoides polygyrus. Within a 2 h incubation period, all the cysteine proteinases, with the exceptio...

journal_title：Parasitology

authors： Stepek G,Buttle DJ,Duce IR,Lowe A,Behnke JM

更新日期：2005-02-01 00:00:00

abstract：:Immunization against the protozoan Theileria parva by infection and treatment has proved to be very efficient for the control of East Coast fever, an acute and often-fatal lymphoproliferative tick-borne disease of cattle in Eastern, Central and Southern Africa. The immunizing dose of live T. parva sporozoites used in ...

journal_title：Parasitology

authors： Marcotty T,Speybroeck N,Berkvens D,Chaka G,Besa R,Madder M,Dolan T,Losson B,Brandt J

更新日期：2004-02-01 00:00:00

abstract：:Oocysts of Cryptosporidium parvum showed relatively low levels of SOD activity. The SOD which had a pI of 4.8 and an approximate molecular weight of 35 kDa appeared to be iron dependent. Catalase, glutathione transferase, glutathione reductase and glutathione peroxidase activity could not be detected, nor could trypan...

journal_title：Parasitology

authors： Entrala E,Mascaro C,Barrett J

更新日期：1997-01-01 00:00:00

abstract：:Microvilli are developed on the surface of Schistosoma mansoni schistosomula during penetration of the host skin; they form rapidly but are lost approximately 90 min after penetration. Identical microvilli are also formed on schistosomula which have penetrated a mouse skin preparation in vitro, and on schistosomula pr...

journal_title：Parasitology

authors： McLaren DJ,Hockley DJ

更新日期：1976-10-01 00:00:00

abstract：:The rapid elimination of the intestinal phase of Trichinella spiralis in NIH mice is associated with progressive inflammation of the intestinal tract. The non-specific effects of this inflammation were studied in mice concurrently infected with an unrelated parasite, Hymenolepis diminuta, which does not stimulate a vi...

journal_title：Parasitology

authors： Behnke JM,Bland PW,Wakelin D

更新日期：1977-08-01 00:00:00

abstract：:Cells of Leishmania donovani in co-culture with Trypanosoma brucei, were severely affected in their growth, resulting in swelling and subsequent lysis. Similar effects were also observed when Crithidia luciliae or Phytomonas sp. were co-cultured with T. brucei. Direct contact between the cells under investigation and ...

journal_title：Parasitology

authors： Coppens I,Ter Kuile BH,Opperdoes FR

更新日期：1992-12-01 00:00:00

abstract：:We describe a laboratory model using Eimeria falciformis and E. pragensis to investigate some of the interactions in double-species infections of Eimeria. Mice were given trickle infections by oral inoculation of 100 sporulated oocysts of one species at 3 or 4 day intervals throughout the experiments and, once immunit...

journal_title：Parasitology

authors： Shehu K,Nowell F

更新日期：1998-11-01 00:00:00

abstract：:Biochemical characterization of 137 Leishmania braziliensis isolates from South and Central America, and from selected endemic foci in Bolivia, Brazil and Colombia, performed by isoenzymatic electrophoresis using 10 enzymatic systems, showed a high enzymatic polymorphism (44 zymodemes obtained) based on the variation ...

journal_title：Parasitology

authors： Chouicha N,Lanotte G,Pratlong F,Cuba Cuba CA,Velez ID,Dedet JP

更新日期：1997-10-01 00:00:00

abstract：:Trials were carried out to study the humoral immune response of blackflies to filariae following infection using the intrathoracic injection technique. An induced 66 kDa protein was abundant in the haemolymph of the European species Simulium ornatum following infection with bovine Onchocerca lienalis. This protein was...

journal_title：Parasitology

authors： Hagen HE,Grunewald J,Ham PJ

更新日期：1994-12-01 00:00:00

abstract：:The magnetic resonance imaging (MRI) appearance of the brain and spinal cord in humans with neuroangiostrongyliasis (NA) due to Angiostrongylus cantonensis infection has been well reported. Equivalent studies in animals are lacking. This case series describes clinical and MRI findings in 11 dogs with presumptively or ...

journal_title：Parasitology

authors： Wun MK,Malik R,Yu J,Chow KE,Lau M,Podadera JM,Webster N,Lee R,Šlapeta J,Davies S

更新日期：2020-09-21 00:00:00

abstract：:Parasite transmission can be altered via the removal of parasites by the ambient communities in which parasite-host interactions take place. However, the mechanisms driving parasite removal remain poorly understood. Using marine trematode cercariae as a model system, we investigated the effects of consumer and host bo...

journal_title：Parasitology

authors： Welsh JE,Hempel A,Markovic M,van der Meer J,Thieltges DW

更新日期：2019-03-01 00:00:00

abstract：:Perkinsus marinus is a protozoan responsible for dramatic mortality in the Eastern oyster, Crassostrea virginica, but not in the Pacific oyster, C. gigas. To understand the host-parasite relationship, we inoculated P. marinus trophozoites into the shell cavity of C. gigas and measured, over 2 months, (i) intensity of ...

journal_title：Parasitology

authors： Romestand B,Corbier F,Roch P

更新日期：2002-10-01 00:00:00

abstract：:In situations where malaria eradication is not an option in the foreseeable future the emphasis must be on the control of morbidity and mortality due to malaria. Under such circumstances drawing a distinction between malarial parasitization and malarial disease may be important for workers in both field and laboratory...

journal_title：Parasitology

authors： Marsh K

更新日期：1992-01-01 00:00:00

abstract：:Many zoonotic disease agents are transmitted between hosts by arthropod vectors, including fleas, but few empirical studies of host-vector-microparasite dynamics have investigated the relative importance of hosts and vectors. This study investigates the dynamics of 4 closely related Bartonella species and their flea v...

journal_title：Parasitology

authors： Telfer S,Begon M,Bennett M,Bown KJ,Burthe S,Lambin X,Telford G,Birtles R

更新日期：2007-03-01 00:00:00

abstract：:In areas where malaria is endemic, helminthic infections, caused by intestinal or filarial parasites, commonly coexist with malaria in the same individual. This study investigates the course of Plasmodium berghei malaria infection in CBA/J mice inoculated with irradiated attenuated 3rd-stage larvae (L3) of Brugia paha...

journal_title：Parasitology

authors： Yan Y,Inuo G,Akao N,Tsukidate S,Fujita K

更新日期：1997-04-01 00:00:00

abstract：:Prevention of heartworm disease caused by Dirofilaria immitis in domestic dogs and cats relies on a single drug class, the macrocyclic lactones (MLs). Recently, it has been demonstrated that ML-resistant D. immitis are circulating in the Mississippi Delta region of the USA, but the prevalence and impact of these resis...

journal_title：Parasitology

authors： Wolstenholme AJ,Evans CC,Jimenez PD,Moorhead AR

更新日期：2015-09-01 00:00:00

abstract：:Distribution of Leptorhynchoides thecatus (Acanthocephala: Rhadinorhynchidae) among the pyloric caeca and the relationship between site and rate of maturation were studied in laboratory infections of 10, 25 and 40 cystacanths fed to green sunfish, Lepomis cyanellus. After 1 week fish fed at each intensity had signific...

journal_title：Parasitology

authors： Ewald JA,Nickol BB

更新日期：1989-06-01 00:00:00

abstract：:Why do parasites kill their hosts? During this past decade, research in three different areas; evolutionary ecology, medical microbiology, and population genetics has provided theory and data that address this and related questions of selection and the evolution and maintenance of parasite virulence. A general theory ...

journal_title：Parasitology

authors： Levin BR,Svanborg Edén C

更新日期：1990-01-01 00:00:00

abstract：:A 196 bp fragment of cloned kinetoplast (k) DNA of Leishmania infantum has been sequenced and shown to be diagnostic for this species. The DNA from 10(4)-10(5) promastigotes was routinely and specifically detected in crude dot blots of whole cells lysed in situ, and there was no cross-hybridization with 10(6) cells of...

journal_title：Parasitology

authors： Gramiccia M,Smith DF,Angelici MC,Ready PD,Gradoni L

更新日期：1992-08-01 00:00:00

abstract：:American trypanosamiasis occurs in nature as a sylvatic cycle, where Trypanosoma cruzi interacts with wild triatomines and mammalian reservoirs, such as marsupials, rodents, armadillos and other animals. Due to difficulties in trying to isolate T. cruzi stocks from the sylvatic cycle, very few studies have been perfor...

journal_title：Parasitology

authors： Fernandes O,Mangia RH,Lisboa CV,Pinho AP,Morel CM,Zingales B,Campbell DA,Jansen AM

更新日期：1999-02-01 00:00:00

abstract：:In Strongyloides ratti-infected rats, 2 peaks of egg excretion were observed; a large one with maximum egg production on days 7-8 of infection and a small more inconspicuous one around day 25. The second peak, which had been ignored in most studies, was produced by adults in the caecum and the colon. The adults were l...

journal_title：Parasitology

authors： Kimura E,Shintoku Y,Kadosaka T,Fujiwara M,Kondo S,Itoh M

更新日期：1999-08-01 00:00:00

abstract：:The fine structure of the oncosphere of Hymenolepis nana has been investigated by transmission and scanning electron microscopy, together with light microscope observations of JB-4 embedded material. The outer surface of the oncosphere is covered by an epithelial layer, termed the embryonic epithelium. Cell types pres...

journal_title：Parasitology

authors： Fairweather I,Threadgold LT

更新日期：1981-06-01 00:00:00

abstract：:Pentastomids comprise a highly specialized taxon of arthropod-like parasites that probably became adapted to the lungs of amphibians and reptiles early in their long evolutionary history. Few other macroparasites exploit this particular niche. Pentastomids are often large, long-lived and yet they cause little observab...

journal_title：Parasitology

authors： Riley J,Henderson RJ

更新日期：1999-01-01 00:00:00

abstract：:Artificially transformed schistosomula of Schistosoma mansoni develop a consistent but small protection against the lethal effects of antibody plus complement when cultured for 24 h in a chemically defined medium. In contrast, they become rapidly resistant to antibody plus complement, when cultured in the presence of ...

journal_title：Parasitology

authors： Tavares CA,Soares RC,Coelho PM,Gazzinelli G

更新日期：1978-10-01 00:00:00

abstract：:Host location by parasites can be achieved by either active or passive mechanisms. In spite of their significance, the efficacy of these methods has been little researched. High fecundity in parasites is discussed in terms of the role it plays in dispersal and transmission. Some concepts developed by mainstream behavi...

journal_title：Parasitology

authors： Rea JG,Irwin SW

更新日期：1994-01-01 00:00:00