Proteomics at the schistosome-mammalian host interface: any prospects for diagnostics or vaccines?

abstract：:A mathematical model of the transmission dynamics of Cowdria ruminantium by the ixodid tick Amblyomma hebraeum in the bovine host is developed and used to investigate the epidemiology of heartwater across a range of vector challenge. The processes described are supported by empirical data. The pattern of outcome measu...

journal_title：Parasitology

authors： O'Callaghan CJ,Medley GF,Peter TF,Perry BD

更新日期：1998-07-01 00:00:00

abstract：:The biodiversity of Trypanosoma cruzi is one of the main factors complicating the understanding of its molecular epidemiology. As an alternative to classical genetic methods, investigators have used DNA-mediated transformation techniques to study this diversity. Recently, transient expression data were shown to correl...

journal_title：Parasitology

authors： Laurent JP,Swindle J

更新日期：1999-12-01 00:00:00

abstract：:Protozoan parasites of the genus Cryptosporidium infect all vertebrate groups and display some host specificity in their infections. It is therefore possible to assume that Cryptosporidium parasites evolved intimately aside with vertebrate lineages. Here we propose a scenario of Cryptosporidium-Vertebrata coevolution ...

journal_title：Parasitology

authors： Garcia-R JC,Hayman DT

更新日期：2016-11-01 00:00:00

abstract：:The response of the plant parasitic nematode, Meloidogyne incognita (J2 stage) to avermectin B2a-23-one is triphasic, comprising an initial loss of locomotor activity where the juveniles remain sensitive to touch, a recovery phase and a final loss of activity where the juveniles are relatively insensitive to touch. In...

journal_title：Parasitology

authors： Wright DJ,Birtle AJ,Roberts IT

更新日期：1984-04-01 00:00:00

abstract：OBJECTIVE:Unravelling the determinants of parasite life-history traits in natural settings is complex. Here, we deciphered the relationships between biotic, abiotic factors and the variation in 4 life-history traits (body size, egg presence, egg number and egg size) in the fish ectoparasite Tracheliastes polycolpus. We...

journal_title：Parasitology

authors： Loot G,Poulet N,Brosse S,Tudesque L,Thomas F,Blanchet S

更新日期：2011-06-01 00:00:00

abstract：:Toxoplasma gondii and Sarcocystis neurona are protozoan parasites with terrestrial definitive hosts, and both pathogens can cause fatal disease in a wide range of marine animals. Close monitoring of threatened southern sea otters (Enhydra lutris nereis) in California allowed for the diagnosis of dual transplacental tr...

journal_title：Parasitology

authors： Shapiro K,Miller MA,Packham AE,Aguilar B,Conrad PA,Vanwormer E,Murray MJ

更新日期：2016-03-01 00:00:00

abstract：:A delayed gamma distribution satisfactorily described the distribution of times to hatching of Ostertagia circumcincta eggs incubated in 0.1% saline at temperatures between 6 and 20 degrees C. Below 6 degree C hatching of eggs was extremely variable. The relationship between rates of development and temperature within...

journal_title：Parasitology

authors： Young RR,Anderson N,Overend D,Tweedie RL,Malafant KW,Preston GA

更新日期：1980-12-01 00:00:00

abstract：:Protective immunity against larval Taenia crassiceps has been shown to rely on T cells; however, the roles of the specific subsets of T cells during infection are not known. To investigate a possible role for gamma delta T cells, this study investigated larval infection in delta-chain knock-out C57BL/6 (deltaKO) and w...

journal_title：Parasitology

authors： Toenjes SA,Spolski RJ,Mooney KA,Kuhn RE

更新日期：1999-10-01 00:00:00

abstract：:We describe a laboratory model using Eimeria falciformis and E. pragensis to investigate some of the interactions in double-species infections of Eimeria. Mice were given trickle infections by oral inoculation of 100 sporulated oocysts of one species at 3 or 4 day intervals throughout the experiments and, once immunit...

journal_title：Parasitology

authors： Shehu K,Nowell F

更新日期：1998-11-01 00:00:00

abstract：:Alveolar echinococcosis (AE) is a zoonotic parasitic diseases caused by a cestode parasite known as Echinococcus multilocularis. The parasite has a wildlife cycle with definitive hosts (foxes) and small mammals as intermediate hosts (rodents) while humans are the accidental hosts. Parasite infection pressure relation ...

journal_title：Parasitology

authors： Khan A,Ahmed H,Sohail A,Alam F,Simsek S

更新日期：2020-03-01 00:00:00

abstract：:The biological parameters which generate seasonal fluctuations in the size of populations of Caryophyllaeus laticeps are examined in detail. A mathematical model is formulated to describe the dynamics of the adult parasite within the fish host Abramis brama, and the predictions of the model are compared with observed ...

journal_title：Parasitology

authors： Anderson RM

更新日期：1976-06-01 00:00:00

abstract：:The present study was performed on antigen-presenting cells (APCs) of Theileria annulata transformed dendritic cells (TaDCs) and monocyte-derived dendritic cells (MoDCs) to compare differences in antigen presentation and stimulation of T lymphocyte proliferation. Antigen presentation for T lymphocyte proliferation was...

journal_title：Parasitology

authors： Rashid M,Liu J,Guan G,Wang J,Li Z,Hassan MA,Rashid MI,Mukhtar MU,Luo J,Yin H

更新日期：2020-01-01 00:00:00

abstract：:We investigated intestinal trichomonads in western lowland gorillas, central chimpanzees and humans cohabiting the forest ecosystem of Dzanga-Sangha Protected Area in Central African Republic, using the internal transcribed spacer (ITS) region and SSU rRNA gene sequences. Trichomonads belonging to the genus Tetratrich...

journal_title：Parasitology

authors： Petrželková KJ,Smejkalová P,Céza V,Pafčo B,Shutt-Phillips KA,Todd A,Jirků-Pomajbíková K,Benavides J,Modrý D,Čepička I

更新日期：2020-02-01 00:00:00

abstract：:Patterns of genetic subdivision in parasite populations can provide important insights into transmission processes and complement information obtained using traditional epidemiological techniques. We describe mitochondrial sequence variation in 265 Ascaris collected from 62 individual hosts (humans and pigs) from 35 h...

journal_title：Parasitology

authors： Anderson TJ,Romero-Abal ME,Jaenike J

更新日期：1995-02-01 00:00:00

abstract：:Accurately identifying resistance to gastrointestinal nematode infections requires the ability to identify animals with low and high intensities of infection. The pathogenic effects of nematodes depend upon both the length and number of worms, neither of which can be measured in live animals. Indices that predict thes...

journal_title：Parasitology

authors： Mair C,Matthews L,De Cisneros JP,Stefan T,Stear MJ

更新日期：2015-05-01 00:00:00

abstract：:The genomes of more than 20 helminths have now been sequenced. Here we perform a meta-analysis of all sequenced genomes of nematodes and Platyhelminthes, and attempt to address the question of what are the defining characteristics of helminth genomes. We find that parasitic worms lack systems for surface antigenic var...

journal_title：Parasitology

authors： Zarowiecki M,Berriman M

更新日期：2015-02-01 00:00:00

abstract：:Heparin-binding proteins (HBPs) play a key role in Trypanosoma cruzi-host cell interactions. HBPs recognize heparan sulfate (HS) at the host cell surface and are able to induce the cytoadherence and invasion of this parasite. Herein, we analysed the biochemical properties of the HBPs and also evaluated the expression ...

journal_title：Parasitology

authors： Oliveira FO Jr,Alves CR,Silva FS,Côrtes LM,Toma L,Bouças RI,Aguilar T,Nader HB,Pereira MC

更新日期：2013-02-01 00:00:00

abstract：:The surface coat of the 2nd-stage juveniles (J2) of plant-parasitic nematodes is considered to be involved in interactions with microorganisms in the soil and rhizosphere, as well as with the host plant. Characterization of surface antigens might be important in the development of new nematode control strategies. In t...

journal_title：Parasitology

authors： Sharon E,Spiegel Y,Salomon R,Curtis RH

更新日期：2002-08-01 00:00:00

abstract：:Ultrastructural investigations (SEM, TEM) combined with lectin-binding analysis, have revealed concurrent modifications in tegumentary structure and surface glycoconjugates during the establishment and differentiation of Echinococcus multilocularis metacestodes in jirds. The laminated layer, which is amorphous and ric...

journal_title：Parasitology

authors： Leducq R,Gabrion C

更新日期：1992-02-01 00:00:00

abstract：:Conventional mice and congenitally athymic, nude mice were infected with 20 metacercariae of the intestinal trematode Echinostoma revolutum. The sequential events in the pathological changes in the intestine were studied at different intervals post-infection. By day 11 onwards the conventional mice displayed dilatatio...

journal_title：Parasitology

authors： Bindseil E,Christensen NO

更新日期：1984-06-01 00:00:00

abstract：:American trypanosamiasis occurs in nature as a sylvatic cycle, where Trypanosoma cruzi interacts with wild triatomines and mammalian reservoirs, such as marsupials, rodents, armadillos and other animals. Due to difficulties in trying to isolate T. cruzi stocks from the sylvatic cycle, very few studies have been perfor...

journal_title：Parasitology

authors： Fernandes O,Mangia RH,Lisboa CV,Pinho AP,Morel CM,Zingales B,Campbell DA,Jansen AM

更新日期：1999-02-01 00:00:00

abstract：:The twin concepts of zooprophylaxis and the dilution effect originated with vector-borne diseases (malaria), were driven forward by studies on Lyme borreliosis and have now developed into the mantra "biodiversity protects against disease". The basic idea is that by diluting the assemblage of transmission-competent hos...

journal_title：Parasitology

authors： Randolph SE,Dobson AD

更新日期：2012-06-01 00:00:00

abstract：:The ribosomal RNA (rRNA) gene units of Schistosoma mansoni and S. rodhaini, of the lateral spined egg group, have been studied. The schistosome rRNA gene unit consists of a regular interspersion of the two genes encoding the large and small rRNA units with two spacers. The large spacer is not transcribed while the sma...

journal_title：Parasitology

authors： Walker TK,Simpson AJ,Rollinson D

更新日期：1989-02-01 00:00:00

abstract：:The epicontinental fauna of the Iberian Peninsula is strongly influenced by its geographical history. As the possibilities for dispersion of organisms into and from this region were (and still are) limited, the local fauna consists almost exclusively of endemic species. Almost all Iberian freshwater fishes of the fami...

journal_title：Parasitology

authors： Benovics M,Desdevises Y,Šanda R,Vukić J,Scheifler M,Doadrio I,Sousa-Santos C,Šimková A

更新日期：2020-04-01 00:00:00

abstract：:Trials were carried out to study the humoral immune response of blackflies to filariae following infection using the intrathoracic injection technique. An induced 66 kDa protein was abundant in the haemolymph of the European species Simulium ornatum following infection with bovine Onchocerca lienalis. This protein was...

journal_title：Parasitology

authors： Hagen HE,Grunewald J,Ham PJ

更新日期：1994-12-01 00:00:00

abstract：:Due to the low informative value of available morphological characters, cytogenetic and molecular methods, based on rDNA sequencing, were used to characterize adult and larval stages of Phyllodistomum spp. Species studied have 18 chromosomes with comparable absolute and relative lengths. Conventional Giemsa staining a...

journal_title：Parasitology

authors： Petkeviciŭte R,Stunzenas V,Staneviciŭte G

更新日期：2004-12-01 00:00:00

abstract：:The evolution of host specificity and the potential trade-off between being a generalist and a specialist are central issues in the evolutionary ecology of parasites. Different species of parasites or even different populations of the same species often show different degrees of host specificity. However, less is know...

journal_title：Parasitology

authors： Leung TL,Poulin R

更新日期：2010-02-01 00:00:00

abstract：:Like in other trypanosomatids D-glucose is a crucial source of energy to Trypanosoma rangeli, a non-pathogenic parasite that in Central and South America infects triatomine vectors and different mammalian species, including humans. In several trypanosome species, D-glucose transporters were already described and clone...

journal_title：Parasitology

authors： Miletti LC,Koerich LB,Pacheco LK,Steindel M,Stambuk BU

更新日期：2006-12-01 00:00:00

abstract：:Oesophagostomum dentatum stages were investigated for glutathione S-transferase (GST) expression at the protein and mRNA levels. GST activity was detected in all stages (infectious and parasitic stages including third- and fourth-stage larvae of different ages as well as males and females) and could be dose-dependentl...

journal_title：Parasitology

authors： Joachim A,Ruttkowski B

更新日期：2008-09-01 00:00:00

abstract：:Expression of metalloprotease activities during metacyclogenesis of a series of strains and clones of Trypanosoma cruzi was investigated using SDS-polyacrylamide gel electrophoresis with a range of different co-polymerized proteolytic substrates. A complex pattern of metalloprotease expression, with considerable quant...

journal_title：Parasitology

authors： Lowndes CM,Bonaldo MC,Thomaz N,Goldenberg S

更新日期：1996-04-01 00:00:00