Origin of a major infectious disease in vertebrates: The timing of Cryptosporidium evolution and its hosts.

abstract：:A 196 bp fragment of cloned kinetoplast (k) DNA of Leishmania infantum has been sequenced and shown to be diagnostic for this species. The DNA from 10(4)-10(5) promastigotes was routinely and specifically detected in crude dot blots of whole cells lysed in situ, and there was no cross-hybridization with 10(6) cells of...

journal_title：Parasitology

authors： Gramiccia M,Smith DF,Angelici MC,Ready PD,Gradoni L

更新日期：1992-08-01 00:00:00

abstract：:Given the worldwide decline of amphibian populations due to emerging infectious diseases, it is imperative that we identify and address the causative agents. Many of the pathogens recently implicated in amphibian mortality and morbidity have been fungal or members of a poorly understood group of fungus-like protists, ...

journal_title：Parasitology

authors： Raffel TR,Bommarito T,Barry DS,Witiak SM,Shackelton LA

更新日期：2008-02-01 00:00:00

abstract：:To test the homogeneity of 18S sequences within Trypanosoma cruzi, riboprint profiles were separated by temperature gradient gel electrophoresis (TGGE). Upon interpretation of melting curves of fragments within a riboprint profile, there appeared to be two 18S sequence types within each stock examined. Two similar typ...

journal_title：Parasitology

authors： Stothard JR,Frame IA,Carrasco HJ,Miles MA

更新日期：1998-09-01 00:00:00

abstract：:Schistosoma mansoni depends for its survival on glycolysis. Two glycolytic enzymes, glyceraldehyde-3P-dehydrogenase and triose-phosphate dehydrogenase, found in both the adult and schistosomular tegument, have been reported to confer partial protection against cercarial infection. This paper describes the immunogenic ...

journal_title：Parasitology

authors： Mansour JM,McCrossan MV,Bickle QD,Mansour TE

更新日期：2000-05-01 00:00:00

abstract：:DNA barcoding is now a common tool in parasitology and epidemiology, which require good methods for identification not only of parasites and pathogens but vectors and reservoirs. This special issue presents some advances and challenges in barcoding of microbes, parasites, and their vectors and reservoirs. DNA barcodin...

journal_title：Parasitology

authors： Morand S

更新日期：2018-04-01 00:00:00

abstract：:The recent development of genetic methods allows the delineation of species boundaries, especially in organisms where morphological characters are not reliable to differentiate species. However, few empirical studies have used these tools to delineate species among parasitic metazoans. Here we investigate the species ...

journal_title：Parasitology

authors： Pérez-Ponce DE León G,García-Varela M,Pinacho-Pinacho CD,Sereno-Uribe AL,Poulin R

更新日期：2016-11-01 00:00:00

abstract：:Changes in host phenotype are often attributed to manipulation that enables parasites to complete trophic transmission cycles. We characterized changes in host phenotype in a colonial host–endoparasite system that lacks trophic transmission (the freshwater bryozoan Fredericella sultana and myxozoan parasite Tetracapsu...

journal_title：Parasitology

authors： Hartikainen H,Fontes I,Okamura B

更新日期：2013-09-01 00:00:00

abstract：:A serine protease was purified 942-fold from culture supernatant of L. amazonensis promastigotes using (NH4)2SO4 precipitation followed by affinity chromatography on aprotinin-agarose and continuous elution electrophoresis by Prep Cell, yielding a total recovery of 61%. The molecular mass of the active enzyme estimate...

journal_title：Parasitology

authors： Silva-Lopez RE,Coelho MG,De Simone SG

更新日期：2005-07-01 00:00:00

abstract：:In this study, we describe the molecular analysis of zinc-metalloproteases from the abomasal nematode Ostertagia ostertagi which were exclusively recognized by local antibodies of immune cattle. Full-length or partial coding sequences of 4 different zinc-metalloprotease cDNAs of Ostertagia (met-1, -2, -3 and -4) were ...

journal_title：Parasitology

authors： De Maere V,Vercauteren I,Geldhof P,Gevaert K,Vercruysse J,Claerebout E

更新日期：2005-01-01 00:00:00

abstract：:We have recently identified 2 surface proteins in Entamoeba histolytica as intermediate subunits of galactose- and N-acetyl-D-galactosamine-inhibitable lectin (EhIgl1 and EhIgl2); these proteins both contain multiple CXXC motifs. Here, we report the molecular characterization of the corresponding proteins in Entamoeba...

journal_title：Parasitology

authors： Tachibana H,Cheng XJ,Kobayashi S,Okada Y,Itoh J,Takeuchi T

更新日期：2007-12-01 00:00:00

abstract：:Ultrastructural investigations (SEM, TEM) combined with lectin-binding analysis, have revealed concurrent modifications in tegumentary structure and surface glycoconjugates during the establishment and differentiation of Echinococcus multilocularis metacestodes in jirds. The laminated layer, which is amorphous and ric...

journal_title：Parasitology

authors： Leducq R,Gabrion C

更新日期：1992-02-01 00:00:00

abstract：:The phenotypic activity of two 5-nitroindazolinones, i.e. 2-benzyl-1-propyl (22) and 2-benzyl-1-butyl (24) derivatives, previously proposed as anti-Trypanosoma cruzi prototypes, was presently assayed on bloodstream trypomastigotes (BT) of the moderately drug-resistant Y strain. Further exploration of putative targets ...

journal_title：Parasitology

authors： Fonseca-Berzal C,DA Silva CF,Menna-Barreto RF,Batista MM,Escario JA,Arán VJ,Gómez-Barrio A,Soeiro Mde N

更新日期：2016-09-01 00:00:00

abstract：:Parasites of the genera Plasmodium and Haemoproteus (Apicomplexa: Haemosporida) are a diverse group of pathogens that infect birds nearly worldwide. Despite their ubiquity, the ecological and evolutionary factors that shape the diversity and distribution of these protozoan parasites among avian communities and geograp...

journal_title：Parasitology

authors： Fecchio A,Svensson-Coelho M,Bell J,Ellis VA,Medeiros MC,Trisos CH,Blake JG,Loiselle BA,Tobias JA,Fanti R,Coffey ED,DE Faria IP,Pinho JB,Felix G,Braga EM,Anciães M,Tkach V,Bates J,Witt C,Weckstein JD,Ricklefs RE,

更新日期：2017-06-01 00:00:00

abstract：:Philasterides dicentrarchi is a histophagous ciliate causing systemic scuticociliatosis in cultured turbot. This study demonstrates that turbot which survive this disease have serum antibodies that recognize ciliary antigens of this ciliate in ELISA and immobilize/agglutinate the ciliate in vitro. Mouse sera raised ag...

journal_title：Parasitology

authors： Iglesias R,Paramá A,Alvarez MF,Leiro J,Ubeira FM,Sanmartín ML

更新日期：2003-02-01 00:00:00

abstract：:Members of the phylum Microspora are a group of unusual, obligate intracellular eukaryotic parasites that infect a wide range of hosts. However, there are a limited number of microsporidial infections reported in avian hosts, and no parasite species has been defined as an avian pathogen. A microsporidian organism was ...

journal_title：Parasitology

authors： Snowden KF,Logan K,Phalen DN

更新日期：2000-07-01 00:00:00

abstract：:Cystic echinococcosis (CE) is a high prevalence zoonosis among the rural population of Tacuarembó (Uruguay). The correlation between serological data and the incidence of risk factors was studied in a survey carried out in 1998 among rural communities where 480 individuals were examined by means of abdominal sonograph...

journal_title：Parasitology

authors： Hernández A,Cardozo G,Dematteis S,Baz A,Trias N,Nuñez H,Barragué A,López L,Fuentes J,López O,Ferreira C

更新日期：2005-04-01 00:00:00

abstract：:As has been shown previously, immunologically intact mice with patent Schistosoma mansoni infections had a significantly lower mean platelet number than intact uninfected mice (P<0.0001). However, platelet numbers in T-cell deprived mice with patent infections were not significantly different from those in uninfected ...

journal_title：Parasitology

authors： Stanley RG,Ngaiza JR,Atieno E,Jell G,Francklow K,Jackson CL,Parry H,Doenhoff MJ

更新日期：2003-03-01 00:00:00

abstract：:Why do parasites kill their hosts? During this past decade, research in three different areas; evolutionary ecology, medical microbiology, and population genetics has provided theory and data that address this and related questions of selection and the evolution and maintenance of parasite virulence. A general theory ...

journal_title：Parasitology

authors： Levin BR,Svanborg Edén C

更新日期：1990-01-01 00:00:00

abstract：:Susceptibility to oxidative stress is a well-established feature of the malarial parasite. Pharmacologists have taken advantage of this property to design highly effective pro-oxidant antimalarial drugs. Less well appreciated is the fact that nutritional manipulation of host oxidative stress status by dietary means ca...

journal_title：Parasitology

authors： Levander OA,Ager AL Jr

更新日期：1993-01-01 00:00:00

abstract：:Th2-biased inflammation with eosinophilia and IgE production is a hallmark of helminth infections. It is pronounced in hyperreactive onchocerciasis patients ('sowda' or 'local form'), who efficiently kill microfilariae resulting in severe dermatitis and lymphadenitis. In contrast, hyporeactive patients ('generalised f...

journal_title：Parasitology

authors： Korten S,Hoerauf A,Kaifi JT,Büttner DW

更新日期：2011-01-01 00:00:00

abstract：:Fractionation of Schistosoma mansoni cercariae gland secretion on a Sephadex G-150 column followed by a Superose-12 column in an FPLC system, isolated a 47 kDa protease which migrated as a single band on SDS-PAGE gels. A monoclonal antibody (MAb) was produced which recognizes only the 47 kDa protease, and an immuno-af...

journal_title：Parasitology

authors： Chavez-Olortegui C,Resende M,Tavares CA

更新日期：1992-10-01 00:00:00

abstract：:The evolution of host specificity and the potential trade-off between being a generalist and a specialist are central issues in the evolutionary ecology of parasites. Different species of parasites or even different populations of the same species often show different degrees of host specificity. However, less is know...

journal_title：Parasitology

authors： Leung TL,Poulin R

更新日期：2010-02-01 00:00:00

abstract：:RNA extracted from purified parasites of Plasmodium knowlesi was fractionated using agarose gel electrophoresis. Preparations from para sites grown both in vivo and in vitro contained species of RNA with sedimentation coefficients of 4-0S, 5-0S, 16-6S, 24-2S, 31-4S, 38-0S and 48-3S. There was less RNA present in paras...

journal_title：Parasitology

authors： Trigg PI,Shakespeare PG,Burt SJ,Kyd SI

更新日期：1975-10-01 00:00:00

abstract：:It is suspected that host-parasite interactions are influenced by climatic oscillations such as the North Atlantic Oscillation (NAO). However, the effects of climatic oscillations on host-parasite interactions have never been investigated. A long-term (1982-1999) dataset of the host snail Lymnaea stagnalis and tremato...

journal_title：Parasitology

authors： Doi H,Yurlova NI

更新日期：2011-07-01 00:00:00

abstract：:Resistance to diclazuril was induced by 10 passages of the Houghton strains of Eimeria acervulina and E. tenella in chickens given progressively greater concentrations of the drug. This resistance was, however, not complete since the drug retained some efficacy against the drug-passaged lines. Attempts to passage the ...

journal_title：Parasitology

authors： Chapman HD

更新日期：1989-10-01 00:00:00

abstract：:The behavioural responses of Onchocerca lienalis microfilariae (mf) to tissue factors of the surrogate black fly host, Simulium vittatum, were studied using a novel in vitro bioassay. Mf accumulated towards thoracic tissues to a density 4 times higher than towards abdominal tissues, despite the larger surface area and...

journal_title：Parasitology

authors： Lehmann T,Cupp SM,Cupp WE

更新日期：1995-04-01 00:00:00

abstract：:In a recent study by our group on the prevalence of intestinal parasitic infections and on the knowledge, attitudes and practices of local residents of Campos dos Goytacazes, Rio de Janeiro, Brazil, we observed that about 50% of the inhabitants were parasitized and had some knowledge of intestinal parasitic infections...

journal_title：Parasitology

authors： Pereira AP,Alencar MF,Cohen SC,Souza-Júnior PR,Cecchetto F,Mathias LS,Santos CP,Almeida JC,de Moraes Neto AH

更新日期：2012-05-01 00:00:00

abstract：:Solid experimental evidence indicates that EBA-175 is used as a ligand by the Plasmodium falciparum merozoite to bind to human RBC, via different binding processing fragments. Using synthetic peptides and specific receptor-ligand interaction methodology, we have identified 6 high-activity binding sequences from the EB...

journal_title：Parasitology

authors： Rodriguez LE,Urquiza M,Ocampo M,Suarez J,Curtidor H,Guzman F,Vargas LE,Triviños M,Rosas M,Patarroyo ME

更新日期：2000-03-01 00:00:00

abstract：:Species composition of wild reservoir hosts can influence the transmission and maintenance of multi-host vector borne pathogens. The 'pace of life' hypothesis proposes that the life history strategy of reservoir hosts can influence pathogen transmission of vector borne generalist pathogens. We use empirical data to pa...

journal_title：Parasitology

authors： Erazo D,Cordovez J,Cabrera C,Calzada JE,Saldaña A,Gottdenker NL

更新日期：2017-12-01 00:00:00

abstract：:This study assessed the role of historical processes on the geographic isolation, molecular evolution, and morphological diversification of host-parasite populations from the southern Brazilian coast. Adult specimens of Scleromystax barbatus and Scleromystax macropterus were collected from the sub-basin of the Nhundia...

journal_title：Parasitology

authors： Bueno-Silva M,Boeger WA

更新日期：2019-09-01 00:00:00