Low levels of transforming growth factor-beta (TGF-beta) and reduced suppression of Th2-mediated inflammation in hyperreactive human onchocerciasis.

abstract：:Ligand-gated chloride channels (LGCCs) are key components of the nervous system of parasitic nematodes and important targets for anthelmintics. Here, we describe the isolation and characterization of a novel member of the LGCC gene family (HcLGCC1) from the parasitic nematode Haemonchus contortus. Sequence analysis re...

journal_title：Parasitology

authors： Forrester SG,Siddiqui SZ

更新日期：2008-04-01 00:00:00

abstract：:Studies on the nutrition and physiology of Trichomonas vaginalis have been hampered by the lack of a defined synthetic medium in which to grow the organism. New synthetic media free of ill-defined supplements and serum which support good growth of T. vaginalis have been developed in this study. The first successful ap...

journal_title：Parasitology

authors： Linstead D

更新日期：1981-08-01 00:00:00

abstract：:In recent years, a malaria infection of humans in South East Asia, originally diagnosed as a known human-infecting species, Plasmodium malariae, has been identified as a simian parasite, Plasmodium knowlesi. This species had been subject to considerable investigation in monkeys since the 1930s. With the development of...

journal_title：Parasitology

authors： Butcher GA,Mitchell GH

更新日期：2018-01-01 00:00:00

abstract：:Ivermectin treatment may induce severe adverse reactions in some individuals heavily infected with Loa loa. This hampers the implementation of mass ivermectin treatment against onchocerciasis in areas where Onchocerca volvulus and L. loa are co-endemic. In order to identify factors, including co-infections, which may ...

journal_title：Parasitology

authors： Pion SD,Clarke P,Filipe JA,Kamgno J,Gardon J,Basáñez MG,Boussinesq M

更新日期：2006-06-01 00:00:00

abstract：:The glycolytic enzyme triosephosphate isomerase catalyses the isomerization between glyceraldehyde 3-phosphate and dihydroxyacetone phosphate. Here we report that Trichomonas vaginalis contains 2 fully functional tpi genes. Both genes are located in separated chromosomal context with different promoter regulatory elem...

journal_title：Parasitology

authors： Figueroa-Angulo EE,Estrella-Hernández P,Salgado-Lugo H,Ochoa-Leyva A,Gómez Puyou A,Campos SS,Montero-Moran G,Ortega-López J,Saab-Rincón G,Arroyo R,Benítez-Cardoza CG,Brieba LG

更新日期：2012-11-01 00:00:00

abstract：:When eggs of the monogenean Dictyocotyle coeliaca, a parasite from the body cavity of Raja naevus, are incubated in alternating 12 h periods of light and darkness at 12 degrees C the marginal hooklets appear between 75 and 90 days after collecting the eggs from the host's body cavity and hatching begins after about 10...

journal_title：Parasitology

authors： Kearn GC

更新日期：1975-02-01 00:00:00

abstract：:Neurocysticercosis (NCC) is the most common parasitic disease of the central nervous system (CNS) caused by the larval form of the tapeworm Taenia solium. NCC has a long asymptomatic period with little or no inflammation, and the sequential progression to symptomatic NCC depends upon the intense inflammation associate...

journal_title：Parasitology

authors： Alvarez JI,Mishra BB,Gundra UM,Mishra PK,Teale JM

更新日期：2010-03-01 00:00:00

abstract：:Most, if not all, organisms face attack by natural enemies and will be selected to evolve some form of defence. Resistance may have costs as well as its obvious benefits. These costs may be associated with actual defence or with the maintenance of the defensive machinery irrespective of whether a challenge occurs. In ...

journal_title：Parasitology

authors： Kraaijeveld AR,Ferrari J,Godfray HC

更新日期：2002-01-01 00:00:00

abstract：:A new histozoic species of myxosporean was found to infect the gill filaments, gut, kidney and liver of the freshwater teleost Leporinus friderici, collected from the estuarine region of the Amazon, near the city of Belém, Brazil. The plasmodia show asynchronous development, at any one time composed of mature spores a...

journal_title：Parasitology

authors： Casal G,Matos E,Azevedo C

更新日期：2003-04-01 00:00:00

abstract：:Studies of the kinetics of adenosine transport were carried out on the P1 and P2 transporters of drug-sensitive Trypanosoma evansi and its cloned derivative, resistant to the melaminophenyl arsenical Mel CY. Characterization of adenosine uptake was made by estimation of the maximum concentration taken up at time infin...

journal_title：Parasitology

authors： Suswam EA,Ross CA,Martin RJ

更新日期：2003-12-01 00:00:00

abstract：:In this study, the proteome of axenically grown Entamoeba histolytica parasites was explored by two-dimensional gel electrophoresis (2-DE), employing a practical and effective procedure for the solubilization of E. histolytica proteins. Approximately 900 protein species in the pH range between 4 and 7 were detected by...

journal_title：Parasitology

authors： Tolstrup J,Krause E,Tannich E,Bruchhaus I

更新日期：2007-02-01 00:00:00

abstract：:The complete nucleotide sequence of the mitochondrial genome was determined for the fish tapeworm Diphyllobothrium latum. This genome is 13,608 bp in length and encodes 12 protein-coding genes (but lacks the atp8), 22 transfer RNA (tRNA) and 2 ribosomal RNA (rRNA) genes, corresponding to the gene complement found thus...

journal_title：Parasitology

authors： Park JK,Kim KH,Kang S,Jeon HK,Kim JH,Littlewood DT,Eom KS

更新日期：2007-05-01 00:00:00

abstract：:The understanding of the patterns and processes underlying the structure of parasite communities has progressed significantly in the last years; however, much of the evidence available to date on parasite community comes from unconfirmed studies. In this study the ectoparasite communities of 2 related rockfishes, Seba...

journal_title：Parasitology

authors： González MT,Oliva ME

更新日期：2006-09-01 00:00:00

abstract：:Immunization against the protozoan Theileria parva by infection and treatment has proved to be very efficient for the control of East Coast fever, an acute and often-fatal lymphoproliferative tick-borne disease of cattle in Eastern, Central and Southern Africa. The immunizing dose of live T. parva sporozoites used in ...

journal_title：Parasitology

authors： Marcotty T,Speybroeck N,Berkvens D,Chaka G,Besa R,Madder M,Dolan T,Losson B,Brandt J

更新日期：2004-02-01 00:00:00

abstract：:Costa Rica is near malaria elimination. This achievement has followed shifts in malaria health policy. Here, we evaluate the impacts that different health policies have had on malaria transmission in Costa Rica from 1913 to 2018. We identified regime shifts and used regression models to measure the impact of different...

journal_title：Parasitology

authors： Chaves LF,Ramírez Rojas M,Prado M,Garcés JL,Salas Peraza D,Marín Rodríguez R

更新日期：2020-08-01 00:00:00

abstract：:Phylogenetic relationships among Trypanosoma rangeli isolates from man, wild mammals and triatomine bugs from widespread geographical origin were inferred by comparison of the small subunit of ribosomal gene sequences. The phylogenetic trees indicated that the subgenus Herpetosoma is polyphyletic and strongly supporte...

journal_title：Parasitology

authors： Da Silva FM,Noyes H,Campaner M,Junqueira AC,Coura JR,Añez N,Shaw JJ,Stevens JR,Teixeira MM

更新日期：2004-11-01 00:00:00

abstract：:The molecular phylogeny and morphology of the oxyuroid nematode genus Aspiculuris from voles and house mice has been examined. Worms collected from Myodes glareolus in Poland, Eire and the UK are identified as Aspiculuris tianjinensis, previously known only from China, while worms from Mus musculus from a range of loc...

journal_title：Parasitology

authors： Behnke JM,Stewart A,Bajer A,Grzybek M,Harris PD,Lowe A,Ribas A,Smales L,Vandegrift KJ

更新日期：2015-10-01 00:00:00

abstract：:Highly purified mitochondrial fractions have been isolated from the intraerythrocytic stages of two mammalian Plasmodium spp., Plasmodium yoelii of rodents and Plasmodium falciparum of man. Mitochondria of the former parasite are cristate whereas those of the latter are essentially acristate. Isolated mitochondria fro...

journal_title：Parasitology

authors： Fry M,Beesley JE

更新日期：1991-02-01 00:00:00

abstract：:An egg-adapted line of Eimeria necatrix has now been passaged 40 times in the chorio-allantoic membranes of embryonated eggs. Between the 21st and 40th passage in eggs the parasite was subjected to a selection for precocious development, and its pre-patent period in this host is now 123-125 h. The parasite continued t...

journal_title：Parasitology

authors： Shirley MW,Bellatti MA,Millard BJ

更新日期：1982-04-01 00:00:00

abstract：:Parasites have a major impact on global finfish and shellfish aquaculture, having significant effects on farm production, sustainability and economic viability. Parasite infections and impacts can, according to pathogen and context, be considered to be either unpredictable/sporadic or predictable/regular. Although bot...

journal_title：Parasitology

authors： Shinn AP,Pratoomyot J,Bron JE,Paladini G,Brooker EE,Brooker AJ

更新日期：2015-01-01 00:00:00

abstract：:Toxoplasmosis is largely present in rural areas but its spatial distribution in this environment remains poorly known. In particular, it is unclear if areas of high density of cats, the only hosts excreting Toxoplasma gondii, constitute foci of high prevalence. To improve our understanding of the spatial distribution ...

journal_title：Parasitology

authors： Gotteland C,Chaval Y,Villena I,Galan M,Geers R,Aubert D,Poulle ML,Charbonnel N,Gilot-Fromont E

更新日期：2014-02-01 00:00:00

abstract：:A survey was carried out to determine values for the prevalence and intensity of infection of intestinal helminths in children living in Cocle Province, Republic of Panama. The data set consisted of the results of microscopic examinations (modified Kato Katz technique) of stool samples collected in November 1987 from ...

journal_title：Parasitology

authors： Robertson LJ,Crompton DW,Walters DE,Nesheim MC,Sanjur D,Walsh EA

更新日期：1989-10-01 00:00:00

abstract：:The World Health Organization announced in November 2014 at the fourth international meeting on 'the control of neglected zoonotic diseases - from advocacy to action', that intervention tools for eliminating Taenia solium taeniosis/cysticercosis (TSTC) are in place. The aim of this work was to elucidate theoretical ou...

journal_title：Parasitology

authors： Johansen MV,Trevisan C,Gabriël S,Magnussen P,Braae UC

更新日期：2017-01-01 00:00:00

abstract：:With the increased availability of multilocus sequence data, the lack of concordance of gene trees estimated for independent loci has focused attention on both the biological processes producing the discord and the methodologies used to estimate phylogenetic relationships. What has emerged is a suite of new analytical...

journal_title：Parasitology

authors： Knowles LL,Klimov PB

更新日期：2011-11-01 00:00:00

abstract：:Cercariae of the bird schistosome Trichobilharzia regenti and of the human schistosome Schistosoma mansoni employ proteases to invade the skin of their definitive hosts. To investigate whether a similar proteolytic mechanism is used by both species, cercarial extracts of T. regenti and S. mansoni were biochemically ch...

journal_title：Parasitology

authors： Kasný M,Mikes L,Dalton JP,Mountford AP,Horák P

更新日期：2007-10-01 00:00:00

abstract：:Expression of metalloprotease activities during metacyclogenesis of a series of strains and clones of Trypanosoma cruzi was investigated using SDS-polyacrylamide gel electrophoresis with a range of different co-polymerized proteolytic substrates. A complex pattern of metalloprotease expression, with considerable quant...

journal_title：Parasitology

authors： Lowndes CM,Bonaldo MC,Thomaz N,Goldenberg S

更新日期：1996-04-01 00:00:00

abstract：:We have studied the genomic organization and transcription of the histone H2A genes in the protozoan parasite Leishmania infantum. In the parasite genome 2 gene clusters exist, each containing 3 H2A gene copies. Sequence analyses showed the existence of significant sequence divergence among the H2A genes, mainly in th...

journal_title：Parasitology

authors： Soto M,Quijada L,Larreta R,Iborra S,Alonso C,Requena JM

更新日期：2003-08-01 00:00:00

abstract：:Australian tea tree oil (TTO) and its extract terpinen-4-ol (T4O) are found to be effective in moderating demodex-related diseases. Their possible effects are lowering the mite counts, relieving the demodex-related symptoms and modulating the immune system especially the inflammatory response. This review summarizes t...

journal_title：Parasitology

authors： Lam NSK,Long XX,Griffin RC,Chen MK,Doery JC

更新日期：2018-10-01 00:00:00

abstract：:This study was conducted to quantify the association between meteorological variables and incidence of Plasmodium falciparum in areas with unstable malaria transmission in Ethiopia. We used morbidity data pertaining to microscopically confirmed cases reported from 35 sites throughout Ethiopia over a period of approxim...

journal_title：Parasitology

authors： Abeku TA,De Vlas SJ,Borsboom GJ,Tadege A,Gebreyesus Y,Gebreyohannes H,Alamirew D,Seifu A,Nagelkerke NJ,Habbema JD

更新日期：2004-06-01 00:00:00

abstract：:The complete small subunit ribosomal RNA (srRNA) gene of Theileria parva was cloned and sequenced. Two primers were designed which permitted the specific amplification of part of the Theileria srRNA gene from Theileria-infected cell line samples which were predominantly (> 95%) bovine DNA. The sequence of the central ...

journal_title：Parasitology

authors： Allsopp BA,Baylis HA,Allsopp MT,Cavalier-Smith T,Bishop RP,Carrington DM,Sohanpal B,Spooner P

更新日期：1993-08-01 00:00:00