Experimental combination therapy using low doses of benznidazole and allopurinol in mouse models of Trypanosoma cruzi chronic infection.

abstract：:Trypanosomes are blood-borne parasites that can infect a variety of different vertebrates, including animals and humans. This study aims to broaden scientific knowledge about the presence and biodiversity of trypanosomes in Australian bats. Molecular and morphological analysis was performed on 86 blood samples collect...

journal_title：Parasitology

authors： Austen JM,Van Kampen E,Egan SL,O'Dea MA,Jackson B,Ryan UM,Irwin PJ,Prada D

更新日期：2020-12-01 00:00:00

abstract：:During the early stages of the primary Plasmodium chabaudi chabaudi AS parasitaemia in CBA/Ca mice this parasite invaded normocytes, but as the parasitaemia developed increasing numbers of parasites were seen within reticulocytes. During and just after peak parasitaemia, as further parasite replication was controlled,...

journal_title：Parasitology

authors： Jarra W,Brown KN

更新日期：1989-10-01 00:00:00

abstract：:Leishmania produce several types of mucin-like glycoproteins called proteophosphoglycans (PPGs) some of which are secreted while others are found on the surface of promastigotes and amastigotes. These proteins are thought to be important in the transmission, invasion and subsequent intracellular survival of parasites....

journal_title：Parasitology

authors： Samant M,Sahasrabuddhe AA,Singh N,Gupta SK,Sundar S,Dube A

更新日期：2007-08-01 00:00:00

abstract：:SIV rats infected with a high dose (50,000 oocysts) of Eimeria nieschulzi displayed clinical symptoms of coccidiosis such as diarrhoea (days 6 and 7 post-primary infection) and weight loss (days 6-8 post-primary infection) and were completely immune to challenge with a similar dose. The ability of rats to produce tumo...

journal_title：Parasitology

authors： Smith NC,Ovington KS,Deplazes P,Eckert J

更新日期：1995-07-01 00:00:00

abstract：:In parallel with massive research efforts in human schistosomiasis over the past 30 years, persistent efforts have been made to understand the basis for compatibility and incompatibility in molluscan schistosomiasis. Snail plasma contains molecules that are toxic to trematodes, but these seem to kill only species that...

journal_title：Parasitology

authors： Bayne CJ,Hahn UK,Bender RC

更新日期：2001-01-01 00:00:00

abstract：:The development of drug resistance by the present Houghton strain of Eimeria tenella to the quinolones, methyl benzoquate and buquinolate, was found to take place after a single experimental passage. The development of resistance was independent of drug selection pressure and showed cross resistance to other quinolone...

journal_title：Parasitology

authors： Chapman HD

更新日期：1975-08-01 00:00:00

abstract：:Infections with Haemonchus contortus are a major constraint on ruminant health world-wide. Young lambs are very sensitive to Haemonchus infection. Older lambs and sheep acquire immunity after a continuous or seasonal exposure to the parasite. The mechanisms underlying immunity are still not completely understood. Anti...

journal_title：Parasitology

authors： Schallig HD

更新日期：2000-01-01 00:00:00

abstract：:The complete sequence of the 18S small subunit (SSU) ribosomal DNA of Hammondia hammondi and Sarcocystis mucosa was obtained and compared to SSU rDNA sequences of Neospora caninum, Toxoplasma gondii, Besnoitia besnoiti, 2 species of Frenkelia, 3 species of Isospora, and 13 species of Sarcocystis. Analyses showed that ...

journal_title：Parasitology

authors： Jenkins MC,Ellis JT,Liddell S,Ryce C,Munday BL,Morrison DA,Dubey JP

更新日期：1999-08-01 00:00:00

abstract：:Murine monoclonal antibodies (mAbs) against Neospora caninum tachyzoites were produced to identify the cross-reactive antigens between N. caninum and Toxoplasma gondii. Ten mAbs recognizing cross-reactive antigens of both parasites were obtained and tentatively classified into 6 different groups based on their reactiv...

journal_title：Parasitology

authors： Liao M,Xuan X,Huang X,Shirafuji H,Fukumoto S,Hirata H,Suzuki H,Fujisaki K

更新日期：2005-05-01 00:00:00

abstract：:In a recent study by our group on the prevalence of intestinal parasitic infections and on the knowledge, attitudes and practices of local residents of Campos dos Goytacazes, Rio de Janeiro, Brazil, we observed that about 50% of the inhabitants were parasitized and had some knowledge of intestinal parasitic infections...

journal_title：Parasitology

authors： Pereira AP,Alencar MF,Cohen SC,Souza-Júnior PR,Cecchetto F,Mathias LS,Santos CP,Almeida JC,de Moraes Neto AH

更新日期：2012-05-01 00:00:00

abstract：:Recent publications demonstrated that a fragment of a Neospora caninum ROP2 family member antigen represents a promising vaccine candidate. We here report on the cloning of the cDNA encoding this protein, N. caninum ROP2 family member 1 (NcROP2Fam-1), its molecular characterization and localization. The protein posses...

journal_title：Parasitology

authors： Alaeddine F,Hemphill A,Debache K,Guionaud C

更新日期：2013-07-01 00:00:00

abstract：:Eimerian oocysts were found in 98% of 422 faeces samples from goats in SE England. It was found that 74% of the samples contained thousands or tens of thousands of oocysts/g. Kids less than 1 year old had higher oocyst counts than yearling or adult goats. Nine species of Eimeria were identified, and 65% of the samples...

journal_title：Parasitology

authors： Norton CC

更新日期：1986-04-01 00:00:00

abstract：:The surface coat of the 2nd-stage juveniles (J2) of plant-parasitic nematodes is considered to be involved in interactions with microorganisms in the soil and rhizosphere, as well as with the host plant. Characterization of surface antigens might be important in the development of new nematode control strategies. In t...

journal_title：Parasitology

authors： Sharon E,Spiegel Y,Salomon R,Curtis RH

更新日期：2002-08-01 00:00:00

abstract：:Stability of trichostrogylid populations indicates that some form of density-dependent regulation occurs which could act through fecundity. We present evidence for intraspecific density-dependent effects in 1 of 2, dominant, abomasal nematodes species (Ostertagia gruehneri) of Svalbard reindeer (Rangifer tarandus plat...

journal_title：Parasitology

authors： Irvine RJ,Stien A,Dallas JF,Halvorsen,Langvatn R,Albon SD

更新日期：2001-06-01 00:00:00

abstract：:Bloodstream forms of Trypanosoma congolense (2 clones: ILNat3.1 and IL3000, and 4 stocks: IL2079, IL2466, IL3266 and CP-81) were continuously cultivated in vitro at 34-36 degrees C in the absence of feeder cell layers, using HMI-93 medium which was modified from Iscove's modified Dulbecco's MEM (Flow Laboratories, Irv...

journal_title：Parasitology

authors： Hirumi H,Hirumi K

更新日期：1991-04-01 00:00:00

abstract：:Angiostrongylus cantonensis is a metastrongyloid nematode found widely in the Asia-Pacific region, and the aetiological agent of angiostrongyliasis; a disease characterized by eosinophilic meningitis. Rattus rats are definitive hosts of A. cantonensis, while intermediate hosts include terrestrial and aquatic molluscs....

journal_title：Parasitology

authors： Barratt J,Chan D,Sandaradura I,Malik R,Spielman D,Lee R,Marriott D,Harkness J,Ellis J,Stark D

更新日期：2016-08-01 00:00:00

abstract：:The parasitic roundworms Strongyloides stercoralis (in man) and Strongyloides ratti (in rats) employ environmentally controlled XX/XO sex determination with a pair of X chromosomes and two pairs of autosomes. Strongyloides papillosus (in sheep) has only two pairs of chromosomes, one of which combines the genetic mater...

journal_title：Parasitology

authors： Kulkarni A,Dyka A,Nemetschke L,Grant WN,Streit A

更新日期：2013-12-01 00:00:00

abstract：:Anti-trypanosomiasis vaccination still remains the best theoretical option in the fight against a disease that is continuously hovering between its wildlife reservoir and its reservoir in man and livestock. While antigenic variation of the parasite surface coat has been considered the major obstacle in the development...

journal_title：Parasitology

authors： Magez S,Caljon G,Tran T,Stijlemans B,Radwanska M

更新日期：2010-12-01 00:00:00

abstract：:A study carried out on a sheep farm examined whether Toxoplasma gondii foetal infection and associated abortion occur in successive lambings. We identified 29 ewes that gave birth to lambs on at least 2 successive years over our study period, 2000-2003. Tissue samples from the progeny of these ewes were analysed by PC...

journal_title：Parasitology

authors： Morley EK,Williams RH,Hughes JM,Thomasson D,Terry RS,Duncanson P,Smith JE,Hide G

更新日期：2008-02-01 00:00:00

abstract：:The gastrointestinal nematodes (GIN) stand out as an important cause of disease in small ruminant, especially on goat farm. Widespread resistance to synthetic anthelminthics has stimulated the research for alternative strategies of parasite control, including the use of medicinal plants. The present work summarizes th...

journal_title：Parasitology

authors： Oliveira Santos F,Ponce Morais Cerqueira A,Branco A,José Moreira Batatinha M,Borges Botura M

更新日期：2019-09-01 00:00:00

abstract：:West-central China is an important endemic focus of both alveolar and cystic echinococcosis where several species of intermediate host are commonly infected with Echinococcus granulosus and E. multilocularis . Isolates of E. granulosus were collected from humans and other animals from different geographical areas of Q...

journal_title：Parasitology

authors： Yang YR,Rosenzvit MC,Zhang LH,Zhang JZ,McManus DP

更新日期：2005-10-01 00:00:00

abstract：:A mathematical model of the transmission dynamics of Cowdria ruminantium by the ixodid tick Amblyomma hebraeum in the bovine host is developed and used to investigate the epidemiology of heartwater across a range of vector challenge. The processes described are supported by empirical data. The pattern of outcome measu...

journal_title：Parasitology

authors： O'Callaghan CJ,Medley GF,Peter TF,Perry BD

更新日期：1998-07-01 00:00:00

abstract：:To compare the structures of natural and re-established populations of Ascaris in humans, universal (mass) chemotherapy was carried out at the beginning and the end of the study year using pyrantel pamoate. Worms expelled within 48 h of treatment were collected, their sex determined, and measurements made of length, w...

journal_title：Parasitology

authors： Peng W,Cui X,Zhou X

更新日期：2002-06-01 00:00:00

abstract：:The ribosomal RNA (rRNA) gene units of Schistosoma mansoni and S. rodhaini, of the lateral spined egg group, have been studied. The schistosome rRNA gene unit consists of a regular interspersion of the two genes encoding the large and small rRNA units with two spacers. The large spacer is not transcribed while the sma...

journal_title：Parasitology

authors： Walker TK,Simpson AJ,Rollinson D

更新日期：1989-02-01 00:00:00

abstract：:We describe a laboratory model using Eimeria falciformis and E. pragensis to investigate some of the interactions in double-species infections of Eimeria. Mice were given trickle infections by oral inoculation of 100 sporulated oocysts of one species at 3 or 4 day intervals throughout the experiments and, once immunit...

journal_title：Parasitology

authors： Shehu K,Nowell F

更新日期：1998-11-01 00:00:00

abstract：:An electron microscopical study was made on the development of Eimeria dispersa in the small intestine of the domestic turkey. Turkey poults, 10-14 days of age, were inoculated with oocysts and pieces of intestinal tissue were fixed at intervals between 3.5 and 114 h after inoculation. Sporozoites were occasionally se...

journal_title：Parasitology

authors： Millard BJ,Lawn AM

更新日期：1982-02-01 00:00:00

abstract：:Recent studies of the forces behind the diversification of parasite assemblages have shed light on many aspects of parasite biodiversity. By using only parasite species richness as their measure of diversity, however, previous investigations have ignored the relatedness among parasite species and the taxonomic structu...

journal_title：Parasitology

authors： Luque JL,Mouillot D,Poulin R

更新日期：2004-06-01 00:00:00

abstract：:We have recently identified 2 surface proteins in Entamoeba histolytica as intermediate subunits of galactose- and N-acetyl-D-galactosamine-inhibitable lectin (EhIgl1 and EhIgl2); these proteins both contain multiple CXXC motifs. Here, we report the molecular characterization of the corresponding proteins in Entamoeba...

journal_title：Parasitology

authors： Tachibana H,Cheng XJ,Kobayashi S,Okada Y,Itoh J,Takeuchi T

更新日期：2007-12-01 00:00:00

abstract：:Distribution of Leptorhynchoides thecatus (Acanthocephala: Rhadinorhynchidae) among the pyloric caeca and the relationship between site and rate of maturation were studied in laboratory infections of 10, 25 and 40 cystacanths fed to green sunfish, Lepomis cyanellus. After 1 week fish fed at each intensity had signific...

journal_title：Parasitology

authors： Ewald JA,Nickol BB

更新日期：1989-06-01 00:00:00

abstract：:The reproductive effort of Lepeophtheirus pectoralis (Müller O. F., 1776), a caligid copepod, which is commonly found infecting the European flounder, Platichthys flesus (Linnaeus, 1758), is studied in detail for the first time. Seasonal variation in body dimensions and reproductive effort are analysed. Data for 120 o...

journal_title：Parasitology

authors： Frade DG,Santos MJ,Cavaleiro FI

更新日期：2016-01-01 00:00:00