Blood schizontocidal activity of azithromycin and its combination with alpha/beta arteether against multi-drug resistant Plasmodium yoelii nigeriensis, a novel MDR parasite model for antimalarial screening.

abstract：:Experiments to investigate the metabolism of glycine, L-glutamic acid and L-aspartic acid by Moniliformis moniliformis were carried out by incubating adult worms aerobically for 3 h at 37 degrees C in Tyrode's solution containing either [U-14C]glycine, L-[U-14C]glutamic acid, L-[U-14C]aspartic acid or L-[4-14C]asparti...

journal_title：Parasitology

authors： Ward PF,Crompton DW

更新日期：1987-06-01 00:00:00

abstract：:The cumulative effect of co-infections between pathogen pairs on the haematological response of East African Short-horn Zebu calves is described. Using a longitudinal study design a stratified clustered random sample of newborn calves were recruited into the Infectious Diseases of East African Livestock (IDEAL) study ...

journal_title：Parasitology

authors： Van Wyk IC,Goddard A,de C Bronsvoort BM,Coetzer JA,Handel IG,Hanotte O,Jennings A,Lesosky M,Kiara H,Thumbi SM,Toye P,Woolhouse MW,Penzhorn BL

更新日期：2014-03-01 00:00:00

abstract：:The individual and combined effects of cadmium (Cd) and 3,3',4,4',5-pentachlorobiphenyl (PCB 126) on the antibody response of fish against metazoan parasites were tested. Eels experimentally infected with the swim bladder nematode Anguillicola crassus were exposed to sublethal concentrations of Cd and PCB 126. Cd was ...

journal_title：Parasitology

authors： Sures B,Knopf K

更新日期：2004-04-01 00:00:00

abstract：:Asparaginyl proteinases (or legumains) are a recently identified, novel class of cysteine proteinase which specifically hydrolyse peptide bonds after asparagine residues. Legumains have been implicated in the activation of cysteine proteases, particularly cathepsin B-like proteinases which are thought to help degrade ...

journal_title：Parasitology

authors： Oliver EM,Skuce PJ,McNair CM,Knox DP

更新日期：2006-08-01 00:00:00

abstract：:The glycolytic enzyme triosephosphate isomerase catalyses the isomerization between glyceraldehyde 3-phosphate and dihydroxyacetone phosphate. Here we report that Trichomonas vaginalis contains 2 fully functional tpi genes. Both genes are located in separated chromosomal context with different promoter regulatory elem...

journal_title：Parasitology

authors： Figueroa-Angulo EE,Estrella-Hernández P,Salgado-Lugo H,Ochoa-Leyva A,Gómez Puyou A,Campos SS,Montero-Moran G,Ortega-López J,Saab-Rincón G,Arroyo R,Benítez-Cardoza CG,Brieba LG

更新日期：2012-11-01 00:00:00

abstract：:Plerocercoids of the pseudophyllidean cestode Schistocephalus solidus infect the three-spined stickleback Gasterosteus aculeatus, with important consequences for the biology of host fish. Techniques for culturing the parasite in vitro and generating infective stages that can be used to infect sticklebacks experimental...

journal_title：Parasitology

authors： Barber I,Scharsack JP

更新日期：2010-03-01 00:00:00

abstract：:The outcome of a parasite infection is the result of the interaction between the host and the parasite. In the system we studied, there are 3 critical stages for the outcome of infection of the (intermediate) host, the copepod Macrocyclops albidus, with the cestode Schistocephalus solidus. During the establishment pha...

journal_title：Parasitology

authors： van der Veen IT,Kurtz J

更新日期：2002-04-01 00:00:00

abstract：:Adults of the porocephalid pentastomid Porocephalus crotali infect the lung of rattlesnake definitive hosts and larvae develop in rat intermediate hosts. In the latter, nymphs encyst within a variety of tissue sites (commonly abdominal fat bodies and lungs) and each becomes the focus of an eosinophilic granuloma. From...

journal_title：Parasitology

authors： McHardy P,Riley J,Huntley JF

更新日期：1993-01-01 00:00:00

abstract：:In theory, the age at which maturation occurs in parasitic nematodes is inversely related to pre-maturational mortality rate, and cross-species data on mammalian nematodes are consistent with this prediction. Immunity is a major source of parasite mortality and parasites stand to gain sizeable fitness benefits through...

journal_title：Parasitology

authors： Guinnee MA,Gemmill AW,Chan BH,Viney ME,Read AF

更新日期：2003-11-01 00:00:00

abstract：:Parasites often induce behavioural changes in their host. However, it is not necessarily easy to determine whether these changes are representative of an adaptation of the parasite (parasite manipulation), an adaptive response of the host or a side-effect of infection. In a solitary parasitoid of Drosophila larvae (Le...

journal_title：Parasitology

authors： Varaldi J,Petit S,Boulétreau M,Fleury F

更新日期：2006-06-01 00:00:00

abstract：:Pentastomids comprise a highly specialized taxon of arthropod-like parasites that probably became adapted to the lungs of amphibians and reptiles early in their long evolutionary history. Few other macroparasites exploit this particular niche. Pentastomids are often large, long-lived and yet they cause little observab...

journal_title：Parasitology

authors： Riley J,Henderson RJ

更新日期：1999-01-01 00:00:00

abstract：:Microvilli are developed on the surface of Schistosoma mansoni schistosomula during penetration of the host skin; they form rapidly but are lost approximately 90 min after penetration. Identical microvilli are also formed on schistosomula which have penetrated a mouse skin preparation in vitro, and on schistosomula pr...

journal_title：Parasitology

authors： McLaren DJ,Hockley DJ

更新日期：1976-10-01 00:00:00

abstract：:Schistosoma mansoni egg counts by faecal examination vary considerably and are not very sensitive, so prevalences are underestimated. The distribution of egg counts can adequately be described by a stochastic model which distinguishes variation in counts between persons and variation in repeated counts within a person...

journal_title：Parasitology

authors： De Vlas SJ,Engels D,Rabello AL,Oostburg BF,Van Lieshout L,Polderman AM,Van Oortmarssen GJ,Habbema JD,Gryseels B

更新日期：1997-02-01 00:00:00

abstract：:The first rigorous proof applicable to the migration pathway of an infective juvenile macroparasite inside its host is presented. Third-stage larvae of a homogonic strain of Strongyloides ratti applied in exact doses of less than 20 to the skin of the flank of young rats were recovered 16-40 h later in the naso-fronta...

journal_title：Parasitology

authors： Tindall NR,Wilson PA

更新日期：1988-06-01 00:00:00

abstract：:Cutaneous Leishmaniasis (CL) is considered a neglected tropical disease which in Pakistan can now be considered as a growing public health problem. The exact figures on the magnitude of the disease are lacking both at the national and regional level and only a few health centres are available for diagnosis of CL. The ...

journal_title：Parasitology

authors： Khan A,Sajid R,Gul S,Hussain A,Zehri MT,Naz S,Simsek S,Waseem S,Afzal MS,Naqvi SKUH,Qasim M,Ahmed H

更新日期：2020-12-23 00:00:00

abstract：:The epidemiological and ecological processes which govern the success of multiple-species co-infections are as yet unresolved. Here we investigated prior versus late residency within hosts, meaning which parasite contacts the host first, to determine if the outcomes of intra-host competition are altered. We infected a...

journal_title：Parasitology

authors： Lohr JN,Yin M,Wolinska J

更新日期：2010-09-01 00:00:00

abstract：:Serology is an important tool for the diagnosis of alveolar echinococcosis (AE) in humans. In order to improve serodiagnostic performance, we have developed an in vitro-produced Echinococcus mulilocularis metacestode vesicle fluid (EmVF) antigen for application in an immunoblot assay. Immunoblot analysis of EmVF revea...

journal_title：Parasitology

authors： Müller N,Frei E,Nuñez S,Gottstein B

更新日期：2007-06-01 00:00:00

abstract：:Pelodera strongyloides larvae were found in the conjunctival sacs of Apodemus sylvaticus and Clethrionomys glareolus and in hair follicles of A. sylvaticus. Those in the eyes were 3rd-stage larvae while most of those in the dermis were early 4th stages. There was no evidence of pathology and sections of the skin showe...

journal_title：Parasitology

authors： Hominick WM,Aston AJ

更新日期：1981-08-01 00:00:00

abstract：:Transmission experiments were conducted to compare the transmissibility of genetically different Trypanosoma congolense (Savannah subgroup) strains isolated from cattle in a trypanosomiasis endemic area of eastern Zambia. A total of 17 strains were compared. Three strains were extremely virulent with a short pre-paten...

journal_title：Parasitology

authors： Masumu J,Marcotty T,Ndeledje N,Kubi C,Geerts S,Vercruysse J,Dorny P,van den Bossche P

更新日期：2006-09-01 00:00:00

abstract：:Entomopathogenic nematode infective juveniles are likely to encounter both uninfected and infected insects and host quality depends on the stage of the infection. We hypothesized that nematode response to infected hosts will change over the course of an infection. Here, we tested this hypothesis by focusing on the inf...

journal_title：Parasitology

authors： Ramos-Rodríguez O,Campbell JF,Christen JM,Shapiro-Ilan DI,Lewis EE,Ramaswamy SB

更新日期：2007-05-01 00:00:00

abstract：:Leishmania braziliensis strain M2903 was adapted for growth and serially maintained as amastigotes at 34 degrees C in modified UM-54 medium, with growth curves exhibiting typical log and stationary phases. In late passages, amastigote growth took place in the absence of supplementary haemin and was unaffected when the...

journal_title：Parasitology

authors： Balanco JM,Pral EM,da Silva S,Bijovsky AT,Mortara RA,Alfieri SC

更新日期：1998-02-01 00:00:00

abstract：:The current trend of antimony (Sb) unresponsiveness in the Indian subcontinent is a major impediment to effective chemotherapy of visceral leishmaniasis (VL). Although contributory mechanisms studied in laboratory-raised Sb-R parasites include an up-regulation of drug efflux pumps and increased thiols, their role in c...

journal_title：Parasitology

authors： Mandal G,Wyllie S,Singh N,Sundar S,Fairlamb AH,Chatterjee M

更新日期：2007-11-01 00:00:00

abstract：:Schistosoma mansoni eggs, miracidia and primary sporocysts were labelled with phalloidin-rhodamine to visualize filamentous actin structures. Analysis of these forms by confocal fluorescence microscopy revealed the presence of previously well-defined circular and longitudinal muscle layers. Besides these muscular laye...

journal_title：Parasitology

authors： Bahia D,Avelar LG,Vigorosi F,Cioli D,Oliveira GC,Mortara RA

更新日期：2006-09-01 00:00:00

abstract：:An electron microscopical examination has been made of the fine structure and disposition of pancreatic polypeptide immunoreactive cells associated with the egg-forming apparatus in Diclidophora merlangi. The cell bodies are positioned in the parenchyma surrounding the ootype and taper to axon-like processes that exte...

journal_title：Parasitology

authors： Halton DW,Brennan GP,Maule AG,Shaw C,Johnston CF,Fairweather I

更新日期：1991-06-01 00:00:00

abstract：:Embryonic stages of various Onchocerca species have been used to stimulate resistance in CBA mice to challenge injections with the microfilariae of Onchocerca lienalis. Comparable levels of resistance to challenge (29-37% reductions) were conferred by living, freeze-killed, or sonicated organisms administered with Fre...

journal_title：Parasitology

authors： Carlow CK,Bianco AE

更新日期：1987-06-01 00:00:00

abstract：:During the early stages of the primary Plasmodium chabaudi chabaudi AS parasitaemia in CBA/Ca mice this parasite invaded normocytes, but as the parasitaemia developed increasing numbers of parasites were seen within reticulocytes. During and just after peak parasitaemia, as further parasite replication was controlled,...

journal_title：Parasitology

authors： Jarra W,Brown KN

更新日期：1989-10-01 00:00:00

abstract：:Th2-biased inflammation with eosinophilia and IgE production is a hallmark of helminth infections. It is pronounced in hyperreactive onchocerciasis patients ('sowda' or 'local form'), who efficiently kill microfilariae resulting in severe dermatitis and lymphadenitis. In contrast, hyporeactive patients ('generalised f...

journal_title：Parasitology

authors： Korten S,Hoerauf A,Kaifi JT,Büttner DW

更新日期：2011-01-01 00:00:00

abstract：:The worldwide economic impact of Neospora caninum infection has caused the development of effective vaccines to become one of the main goals in the field of neosporosis research. In this study, the protection conferred by antigens from inactivated whole tachyzoites (TZ) and a tachyzoite-bradyzoite mixture (TZ-BZ) of N...

journal_title：Parasitology

authors： Rojo-Montejo S,Collantes-Fernández E,Rodríguez-Marcos S,Pérez-Zaballos F,López-Pérez I,Prenafeta A,Ortega-Mora LM

更新日期：2011-09-01 00:00:00

abstract：:The development of microgamonts was studied in the small intestine of a 2-day-old cat after oral inoculation with 10(7) bradyzoites of Sarcocystis hirsuta. The cat was given bradyzoites in 2 doses at 2 h apart and killed 4 h later. Gamonts were seen in parasitophorous vacuoles of goblet cells in the epithelium of the ...

journal_title：Parasitology

authors： Dubey JP

更新日期：1983-02-01 00:00:00

abstract：:During a longitudinal study investigating the dynamics of malaria in Ugandan lakeshore communities, a consistently high malaria prevalence was observed in young children despite regular treatment. To explore the short-term performance of artemether-lumefantrine (AL), a pilot investigation into parasite carriage after ...

journal_title：Parasitology

authors： Betson M,Sousa-Figueiredo JC,Atuhaire A,Arinaitwe M,Adriko M,Mwesigwa G,Nabonge J,Kabatereine NB,Sutherland CJ,Stothard JR

更新日期：2014-12-01 00:00:00