The degradation rates of cytoplasmic tRNA, rRNA and mRNA in rats are elevated after infection with Nippostrongylus brasiliensis.

abstract：:Entomopathogenic nematode infective juveniles are likely to encounter both uninfected and infected insects and host quality depends on the stage of the infection. We hypothesized that nematode response to infected hosts will change over the course of an infection. Here, we tested this hypothesis by focusing on the inf...

journal_title：Parasitology

authors： Ramos-Rodríguez O,Campbell JF,Christen JM,Shapiro-Ilan DI,Lewis EE,Ramaswamy SB

更新日期：2007-05-01 00:00:00

abstract：:Small vessels showing inflammatory cell infiltrates were invariably observed in the vicinity of intact Toxoplasma tissue cysts within the brains of mice congenitally infected with the protozoan. Lymphocytes were observed in intimate contact with the luminal aspect of the endothelium, penetrating into the thickened bas...

journal_title：Parasitology

authors： Sims TA,Hay J

更新日期：1995-02-01 00:00:00

abstract：:Most, if not all, organisms face attack by natural enemies and will be selected to evolve some form of defence. Resistance may have costs as well as its obvious benefits. These costs may be associated with actual defence or with the maintenance of the defensive machinery irrespective of whether a challenge occurs. In ...

journal_title：Parasitology

authors： Kraaijeveld AR,Ferrari J,Godfray HC

更新日期：2002-01-01 00:00:00

abstract：:Following cloning of Leishmania (L.) amazonensis kinetoplast DNA two recombinant clones were identified: one specific for L. (L.) amazonensis and the other specific for L. (L.) amazonensis and closely related isolates. DNA sequences from these clones were compared with those of other kinetoplastids and oligonucleotide...

journal_title：Parasitology

authors： Eresh S,McCallum SM,Barker DC

更新日期：1994-11-01 00:00:00

abstract：:The in vivo activity of two cyclosporins, cyclosporin A (CsA) and a non-immunosuppressive derivative of dihydrocylosporin A (DHCsA-d) against three tapeworms, Hymenolepis microstoma, H. diminuta and Mesocestoides corti, has been assessed. CsA reversibly reduced the dry weight of H. microstoma in the mouse, briefly del...

journal_title：Parasitology

authors： Chappell LH,Wastling JM,Hurd H

更新日期：1989-04-01 00:00:00

abstract：:Eimerian oocysts were found in 98% of 422 faeces samples from goats in SE England. It was found that 74% of the samples contained thousands or tens of thousands of oocysts/g. Kids less than 1 year old had higher oocyst counts than yearling or adult goats. Nine species of Eimeria were identified, and 65% of the samples...

journal_title：Parasitology

authors： Norton CC

更新日期：1986-04-01 00:00:00

abstract：:Electrophoresis of secretions collected from Globodera pallida revealed a smeared region between 25 and 50 kDa, and a single band of < 20 kDa. The secretions were used to raise an antiserum (LW1). Immunoblotting of parasite homogenates with LW1 differentiated G. pallida from its sibling species G. rostochiensis and re...

journal_title：Parasitology

authors： Duncan LH,Robertson L,Robertson WM,Kusel JR

更新日期：1997-10-01 00:00:00

abstract：:Many different drug-resistant lines of rodent malaria are available as screening models. It is obligatory to screen new compounds for antimalarial activity against a series of resistant lines in order to identify a compound with potential for the treatment of multi-drug resistant (MDR) malaria infections. Instead of u...

journal_title：Parasitology

authors： Tripathi R,Dhawan S,Dutta GP

更新日期：2005-09-01 00:00:00

abstract：:Cryptosporidium parvum is a zoonotic protozoan parasite that mainly affects the ileum of humans and livestock, with the potential to cause severe enteric disease. We describe the complete life cycle of C. parvum in an in vitro system. Infected cultures of the human ileocecal epithelial cell line (HCT-8) were observed ...

journal_title：Parasitology

authors： Borowski H,Thompson RC,Armstrong T,Clode PL

更新日期：2010-01-01 00:00:00

abstract：:Most human cases of cryptosporidiosis are caused by Cryptosporidium parvum or Cryptosporidium hominis, but the use of molecular diagnostic methods has revealed that several other less common species or genotypes can also be involved. Here, we describe two unusual causes of cryptosporidiosis, one being the recently des...

journal_title：Parasitology

authors： Lebbad M,Beser J,Insulander M,Karlsson L,Mattsson JG,Svenungsson B,Axén C

更新日期：2013-12-01 00:00:00

abstract：:Voltage-gated calcium (Ca2+) channels contribute to impulse propagation in excitable cells and also regulate intracellular levels of Ca2+. High voltage-activated (HVA) Ca2+ channels are heteromultimeric membrane proteins. The pore-forming, voltage-sensing subunit is the alpha1 subunit. We have cloned 3 HVA Ca2+ channe...

journal_title：Parasitology

authors： Kohn AB,Lea J,Roberts-Misterly JM,Anderson PA,Greenberg RM

更新日期：2001-11-01 00:00:00

abstract：:Oocysts of fowl coccidia, suspended in a 12% aqueous solution of alginic acid, were dropped into 5% calcium chloride solution to form beads. Following ingestion by chicks, excystation of sporozoites was not affected. Oocyst viability was best when beads were air-dried to 33% of their original weight and stored in airt...

journal_title：Parasitology

authors： Norton CC,Joyner LP

更新日期：1986-06-01 00:00:00

abstract：:Described in the present study is a major component of the cell wall of 2 of the most pathogenic parasites of molluscs, Perkinsus atlanticus and P. marinus. The component is a high molecular weight protein (233 kDa), which we have named PWP-1 (for Perkinsus wall protein-1). Western blots, using a polyclonal serum gene...

journal_title：Parasitology

authors： Montes JF,Durfort M,Lladó A,García-Valero J

更新日期：2002-05-01 00:00:00

abstract：:The World Health Organization announced in November 2014 at the fourth international meeting on 'the control of neglected zoonotic diseases - from advocacy to action', that intervention tools for eliminating Taenia solium taeniosis/cysticercosis (TSTC) are in place. The aim of this work was to elucidate theoretical ou...

journal_title：Parasitology

authors： Johansen MV,Trevisan C,Gabriël S,Magnussen P,Braae UC

更新日期：2017-01-01 00:00:00

abstract：:The surface morphology of fixed ovarian balls from female Moniliformis dubius, agd 12, 18, 26, 28, 42, 77, 105 and 118 days, has been examined by means of scanning electron microscopy. The appearance of the surface has been found to be variable between ovarian balls from worms of the same and different ages. Some part...

journal_title：Parasitology

authors： Parshad VR,Crompton DW,Martin J

更新日期：1980-10-01 00:00:00

abstract：:Members of the phylum Microspora are a group of unusual, obligate intracellular eukaryotic parasites that infect a wide range of hosts. However, there are a limited number of microsporidial infections reported in avian hosts, and no parasite species has been defined as an avian pathogen. A microsporidian organism was ...

journal_title：Parasitology

authors： Snowden KF,Logan K,Phalen DN

更新日期：2000-07-01 00:00:00

abstract：:Sera from goats and cattle that were infected with two Trypanosoma vivax clones (ILDat 1.2 and ILDat 2.1) derived from different stocks were analysed for antibody activity against the variable surface glycoproteins (VSGs) of the infecting clones by enzyme-linked immune assays (ELISA) and immune lysis. To obtain purifi...

journal_title：Parasitology

authors： Vos GJ,Gardiner PR

更新日期：1990-02-01 00:00:00

abstract：:The 4-aminoquinolines chloroquine (CQ) and amodiaquine (AM) were used to treat Gambian children with uncomplicated falciparum malaria in a randomized drug trial. Blood samples were taken immediately before treatment (day 0), and at day 7 and day 28 after treatment. Samples from those parasitologically positive at day ...

journal_title：Parasitology

authors： Duraisingh MT,Drakeley CJ,Muller O,Bailey R,Snounou G,Targett GA,Greenwood BM,Warhurst DC

更新日期：1997-03-01 00:00:00

abstract：:Bile salts have been identified as an important trigger for excystation of Cryptosporidium oocysts but the hierarchy or synergism of this signal in relation to other triggers involved in excystation is poorly understood. In addition to excystation, bile salts have also been reported to increase the invasiveness of spo...

journal_title：Parasitology

authors： King BJ,Keegan AR,Phillips R,Fanok S,Monis PT

更新日期：2012-10-01 00:00:00

abstract：:Parasite-host interactions mediated by cell surface proteins have been implicated as a critical step in infections caused by the microsporidian Nosema bombycis. Such cell surface proteins are considered as promising diagnostic markers and targets for drug development. However, little research has specifically addresse...

journal_title：Parasitology

authors： Zhao W,Hao Y,Wang L,Zhou Z,Li Z

更新日期：2015-06-01 00:00:00

abstract：:The mechanism by which Giardia lamblia exerts its pathogenicity is likely to be multifactorial. A 58 kDa enterotoxin was purified and characterized from the excretory-secretory product (ESP) of the parasite (Kaur et al. 2001). In the present study an attempt has been made to elucidate the mechanism of action of the ES...

journal_title：Parasitology

authors： Shant J,Ghosh S,Bhattacharyya S,Ganguly NK,Majumdar S

更新日期：2004-10-01 00:00:00

abstract：:The efficiency of treatment of human infections with the unicellular eukaryotic pathogens such as fungi and protozoa remains deeply unsatisfactory. For example, the mortality rates from nosocomial fungemia in critically ill, immunosuppressed or post-cancer patients often exceed 50%. A set of six systemic clinical azol...

journal_title：Parasitology

authors： Lepesheva GI,Friggeri L,Waterman MR

更新日期：2018-12-01 00:00:00

abstract：:Aiming to further characterize the haemocyte subsets in Biomphalaria snails, we have performed a detailed flow cytometric analysis of whole haemolymph cellular components using a multiparametric dual colour labelling procedure. Ethidium bromide/acridine orange fluorescence features were used to first select viable hae...

journal_title：Parasitology

authors： Martins-Souza RL,Pereira CA,Coelho PM,Martins-Filho OA,Negrão-Corrêa D

更新日期：2009-01-01 00:00:00

abstract：:Susceptibility to oxidative stress is a well-established feature of the malarial parasite. Pharmacologists have taken advantage of this property to design highly effective pro-oxidant antimalarial drugs. Less well appreciated is the fact that nutritional manipulation of host oxidative stress status by dietary means ca...

journal_title：Parasitology

authors： Levander OA,Ager AL Jr

更新日期：1993-01-01 00:00:00

abstract：:Infections with Haemonchus contortus are a major constraint on ruminant health world-wide. Young lambs are very sensitive to Haemonchus infection. Older lambs and sheep acquire immunity after a continuous or seasonal exposure to the parasite. The mechanisms underlying immunity are still not completely understood. Anti...

journal_title：Parasitology

authors： Schallig HD

更新日期：2000-01-01 00:00:00

abstract：:During a longitudinal study investigating the dynamics of malaria in Ugandan lakeshore communities, a consistently high malaria prevalence was observed in young children despite regular treatment. To explore the short-term performance of artemether-lumefantrine (AL), a pilot investigation into parasite carriage after ...

journal_title：Parasitology

authors： Betson M,Sousa-Figueiredo JC,Atuhaire A,Arinaitwe M,Adriko M,Mwesigwa G,Nabonge J,Kabatereine NB,Sutherland CJ,Stothard JR

更新日期：2014-12-01 00:00:00

abstract：:Pasteuria penetrans is a Gram-positive endospore-producing bacterium that is a parasite of root-knot nematodes. Attachment of endospores to the cuticle of the nematode is the first stage in the infection process. Western blot analysis with monoclonal and polyclonal antibodies that recognize the 30 kDa heparin-binding ...

journal_title：Parasitology

authors： Mohan S,Fould S,Davies KG

更新日期：2001-09-01 00:00:00

abstract：:The development of a successful vaccine depends not only on the production of the vaccine itself, but also on the design pf the vaccination programme. This involves a better understanding of the epidemiology of the disease to be controlled, the delivery system to be used and the costs involved. This review focuses on ...

journal_title：Parasitology

authors： Bundy DA,Chan MS,Guyatt HL

更新日期：1995-01-01 00:00:00

abstract：:Eukaryotic 5S rRNA, synthesized by RNA polymerase III (Pol III), is an essential component of the large ribosomal subunit. Most organisms contain hundreds of 5S rRNA genes organized into tandem arrays. However, the genome of the protozoan parasite Leishmania major contains only 11 copies of the 5S rRNA gene, which are...

journal_title：Parasitology

authors： Moreno-Campos R,Florencio-Martínez LE,Nepomuceno-Mejía T,Rojas-Sánchez S,Vélez-Ramírez DE,Padilla-Mejía NE,Figueroa-Angulo E,Manning-Cela R,Martínez-Calvillo S

更新日期：2016-12-01 00:00:00

abstract：:Little is known about the effects of infection with Borrelia burgdorferi, the bacterium that causes Lyme disease, on its tick vectors. The purpose of this study was to determine the behavioural and ecological effects of infection by the bacterium in nymphal and adult black-legged (Ixodes scapularis) ticks. We found th...

journal_title：Parasitology

authors： Lefcort H,Durden LA

更新日期：1996-08-01 00:00:00