Killing of schistosomula of Schistosoma mansoni by macrophages: induction by T-cell clone-derived lymphokines and interferon-gamma.

abstract：:In parallel with massive research efforts in human schistosomiasis over the past 30 years, persistent efforts have been made to understand the basis for compatibility and incompatibility in molluscan schistosomiasis. Snail plasma contains molecules that are toxic to trematodes, but these seem to kill only species that...

journal_title：Parasitology

authors： Bayne CJ,Hahn UK,Bender RC

更新日期：2001-01-01 00:00:00

abstract：:The sequence of appearance of specific lytic activity against more than 20 variable antigen types (VATs) of Trypanosoma vivax in the serum of 27 animals belonging to 5 species has been examined. For each host species there was a characteristic course of infection, with differences in height and duration of parasitaemi...

journal_title：Parasitology

authors： Barry JD

更新日期：1986-02-01 00:00:00

abstract：:Seroprevalence data illustrate that human exposure to Toxocara is frequent. Environmental contamination with Toxocara spp. eggs is assumed to be the best indicator of human exposure, but increased risk of exposure has also been associated with many other factors. Reported associations are inconsistent, however, and th...

journal_title：Parasitology

authors： Kanobana K,Devleesschauwer B,Polman K,Speybroeck N

更新日期：2013-07-01 00:00:00

abstract：:Following cloning of Leishmania (L.) amazonensis kinetoplast DNA two recombinant clones were identified: one specific for L. (L.) amazonensis and the other specific for L. (L.) amazonensis and closely related isolates. DNA sequences from these clones were compared with those of other kinetoplastids and oligonucleotide...

journal_title：Parasitology

authors： Eresh S,McCallum SM,Barker DC

更新日期：1994-11-01 00:00:00

abstract：:Most human cases of cryptosporidiosis are caused by Cryptosporidium parvum or Cryptosporidium hominis, but the use of molecular diagnostic methods has revealed that several other less common species or genotypes can also be involved. Here, we describe two unusual causes of cryptosporidiosis, one being the recently des...

journal_title：Parasitology

authors： Lebbad M,Beser J,Insulander M,Karlsson L,Mattsson JG,Svenungsson B,Axén C

更新日期：2013-12-01 00:00:00

abstract：:Anti-trypanosomiasis vaccination still remains the best theoretical option in the fight against a disease that is continuously hovering between its wildlife reservoir and its reservoir in man and livestock. While antigenic variation of the parasite surface coat has been considered the major obstacle in the development...

journal_title：Parasitology

authors： Magez S,Caljon G,Tran T,Stijlemans B,Radwanska M

更新日期：2010-12-01 00:00:00

abstract：:In an experiment to study the infectivity, growth and virulence of Schistocephalus solidus in their first intermediate host, copepods of the species Macrocyclops albidus were kept singly and exposed to up to 9 coracidia. Eleven or 14 days post-infection (p.i.) the presence and growth of the cestode larvae relative to ...

journal_title：Parasitology

authors： Wedekind C

更新日期：1997-09-01 00:00:00

abstract：:Schizont-infected red blood cells (SI-RBC) from Plasmodium berghei-infected mice contain between 2 and 10 times as much sialic acid as uninfected RBC from the same blood (99-550 micrograms/10(10) RBC versus 33-65 micrograms/10(10) RBC). Total RBC samples from infected animals containing up to 63% ring- and trophozoite...

journal_title：Parasitology

authors： Howard RJ,Seeley DC Jr,Kao V,Wember M,Schauer R

更新日期：1986-06-01 00:00:00

abstract：:Sex ratio theory posits that the adaptive proportion of male to female gametocytes of a malaria parasite within the vertebrate host depends on the degree of inbreeding within the vector. Gametocyte sex ratio could be phenotypically flexible, being altered based on the infection's clonal diversity, and thus likely inbr...

journal_title：Parasitology

authors： Osgood SM,Schall JJ

更新日期：2004-01-01 00:00:00

abstract：:Eight major reviews are cited to indicate a recent knowledge explosion on the use of marine parasites as potential indicators of pollution. A literature update is given for the period 1995-2001. An analysis of the publications cited is used to provide 10 refined criteria for selecting parasites as indicator/monitor sp...

journal_title：Parasitology

authors： Williams HH,MacKenzie K

更新日期：2003-01-01 00:00:00

abstract：:The tegumental surface of Schistosoma mansoni sporocysts is the site of both nutritive and immunological interactions with haemolymph cells and plasma of Biomphalaria glabrata, the schistosome intermediate host. Within minutes of being placed in host plasma, sporocysts acquire plasma antigens, and within 3 h host plas...

journal_title：Parasitology

authors： Bayne CJ,Loker ES,Yui MA

更新日期：1986-06-01 00:00:00

abstract：:Schistosoma mansoni depends for its survival on glycolysis. Two glycolytic enzymes, glyceraldehyde-3P-dehydrogenase and triose-phosphate dehydrogenase, found in both the adult and schistosomular tegument, have been reported to confer partial protection against cercarial infection. This paper describes the immunogenic ...

journal_title：Parasitology

authors： Mansour JM,McCrossan MV,Bickle QD,Mansour TE

更新日期：2000-05-01 00:00:00

abstract：:Increased permeability of capillaries and venules, labelled with colloidal carbon, was observed in the superficial mucosa of the small intestine of sheep infected with Trichostrongylus colubriformis. The labelled vessels were restricted to infected portions of the gut, and the intensity of labelling appeared to be re...

journal_title：Parasitology

authors： Barker IK

更新日期：1975-04-01 00:00:00

abstract：:The genetic basis of virulence in a line (YM) of Plasmodium yoelii yoelii was investigated in a cross with a mild line (A/C). The blood forms of the virulent line developed extensively in mature erythrocytes of mice, causing death of the host within 7 days; infections with the mild line were normally restricted to ret...

journal_title：Parasitology

authors： Walliker D,Sanderson A,Yoeli M,Hargreaves BJ

更新日期：1976-04-01 00:00:00

abstract：:The snail Bulinus nasutus 1214 possesses a potent haemagglutinin (end-point titre with human erythrocytes, 2(-18)) in its cell-free haemolymph which also binds to the miracidia (but not other larvae) of the incompatible parasite Schistosoma margrebowiei. We have purified a protein possessing this haemagglutinating pro...

journal_title：Parasitology

authors： Harris RA,Preston TM,Southgate VR

更新日期：1993-02-01 00:00:00

abstract：:Parasite-host interactions mediated by cell surface proteins have been implicated as a critical step in infections caused by the microsporidian Nosema bombycis. Such cell surface proteins are considered as promising diagnostic markers and targets for drug development. However, little research has specifically addresse...

journal_title：Parasitology

authors： Zhao W,Hao Y,Wang L,Zhou Z,Li Z

更新日期：2015-06-01 00:00:00

abstract：:Avian malaria is a vector transmitted disease caused by Plasmodium and recent studies suggest that variation in its prevalence across avian hosts is correlated with a variety of ecological traits. Here we examine the relationship between prevalence and diversity of Plasmodium lineages in southeastern Amazonia and: (1)...

journal_title：Parasitology

authors： Fecchio A,Ellis VA,Bell JA,Andretti CB,D'Horta FM,Silva AM,Tkach VV,Weckstein JD

更新日期：2017-07-01 00:00:00

abstract：:Genome assemblies can form the basis of comparative analyses fostering insight into the evolutionary genetics of a parasite's pathogenicity, host-pathogen interactions, environmental constraints and invasion biology; however, the length and complexity of many parasite genomes has hampered the development of well-resol...

journal_title：Parasitology

authors： Thompson PC,Zarlenga DS,Liu MY,Rosenthal BM

更新日期：2017-09-01 00:00:00

abstract：:A collection of stocks of Trypanosoma brucei rhodesiense isolated in Kenya have been examined for electrophoretic variation in 20 enzymes. The results obtained have been analysed in order to determine whether these trypanosomes are diploid and undergo mating and to determine the genetic distance between T. b. rhodesie...

journal_title：Parasitology

authors： Tait A,Barry JD,Wink R,Sanderson A,Crowe JS

更新日期：1985-02-01 00:00:00

abstract：:Vertically transmitted parasites (VTPs) such as Wolbachia are expected not only to minimize the damage they inflict on their hosts, but also to protect their hosts against the damaging effects of coinfecting parasites. By modifying the fitness costs of the infection, VTPs can therefore play an important role in the ev...

journal_title：Parasitology

authors： Zélé F,Denoyelle J,Duron O,Rivero A

更新日期：2018-05-01 00:00:00

abstract：:A cDNA encoding a beta-galactoside-binding lectin (galectin) was identified by immunoscreening a Haemonchus contortus cDNA library with antisera from lambs vaccinated with a membrane protein complex (H-gal-GP) derived from the parasites' gut. The cDNA sequence, exhibiting a tandem repeat structure and designated Hco-g...

journal_title：Parasitology

authors： Newlands GF,Skuce PJ,Knox DP,Smith SK,Smith WD

更新日期：1999-11-01 00:00:00

abstract：:The numbers, distribution in the small intestine, sexual development and growth (dry weight) of 5-week-old Moniliformis dubius (Acanthocephala) were investigated experimentally in adult, female CFHB rats fed on theoretically isoenergetic diets containing known amounts of fructose in combination with either maize-oil f...

journal_title：Parasitology

authors： Crompton DW,Keymer A,Singhvi A,Nesheim MC

更新日期：1983-02-01 00:00:00

abstract：:The biological parameters which generate seasonal fluctuations in the size of populations of Caryophyllaeus laticeps are examined in detail. A mathematical model is formulated to describe the dynamics of the adult parasite within the fish host Abramis brama, and the predictions of the model are compared with observed ...

journal_title：Parasitology

authors： Anderson RM

更新日期：1976-06-01 00:00:00

abstract：:A 186 bp Echinococcus granulosus-specific repetitive element, TREg, was used to assess genetic variation between strains. In G7 genotype (pig strain) it has the characteristics of a satellite DNA element with a copy number of 23000 per haploid genome. Analysis, by sequencing of TREg monomers, showed a great degree of ...

journal_title：Parasitology

authors： Rosenzvit MC,Canova SG,Kamenetzky L,Guarnera EA

更新日期：2001-10-01 00:00:00

abstract：:Multiplication of Plasmodium parasites within human erythrocytes is essential to malarial disease. The cell-division cycle of this organism, however, is still poorly understood. In other eukaryotes, various techniques for (apparent) cell-cycle synchronization have been used to shed light on the mechanisms involved in ...

journal_title：Parasitology

authors： Naughton JA,Bell A

更新日期：2007-03-01 00:00:00

abstract：:Steroids have been shown to be beneficial in patients and mice with eosinophilic meningitis caused by Angiostrongylus cantonensis infection; however, the mechanism for this beneficial effect is unknown. We speculated that the effect of steroids in eosinophilic meningitis caused by A. cantonensis infection may be media...

journal_title：Parasitology

authors： Tsai HC,Chen YH

更新日期：2020-10-02 00:00:00

abstract：:Plerocercoids of the pseudophyllidean cestode Schistocephalus solidus infect the three-spined stickleback Gasterosteus aculeatus, with important consequences for the biology of host fish. Techniques for culturing the parasite in vitro and generating infective stages that can be used to infect sticklebacks experimental...

journal_title：Parasitology

authors： Barber I,Scharsack JP

更新日期：2010-03-01 00:00:00

abstract：:This study reports that inhibition of Leishmania Topo-I with the minor groove-binding ligands (MGBLs) Hoechst 33342 (Ho342) blocks parasite growth in culture by mechanisms involving DNA breakage. While Ho342 inhibited the replication of several species of Leishmania in a dose- and time-dependent manner, Ho258 was not ...

journal_title：Parasitology

authors： Marquis JF,Drolet M,Olivier M

更新日期：2003-01-01 00:00:00

abstract：:We present observational and experimental evidence that cycles of the Lyme disease spirochaete, Borrelia burgdorferi s.l., can be maintained by sheep in the virtual absence of alternative hosts. A 2-year field study in upland moorland habitats of northwest UK established that sheep feed up to 80% of larval, > 99% of n...

journal_title：Parasitology

authors： Ogden NH,Nuttall PA,Randolph SE

更新日期：1997-12-01 00:00:00

abstract：:Plants containing condensed tannins (CT) may have potential to control gastrointestinal nematodes (GIN) of cattle. The aim was to investigate the anthelmintic activities of four flavan-3-ols, two galloyl derivatives and 14 purified CT fractions, and to define which structural features of CT determine the anti-parasiti...

journal_title：Parasitology

authors： Desrues O,Fryganas C,Ropiak HM,Mueller-Harvey I,Enemark HL,Thamsborg SM

更新日期：2016-04-01 00:00:00