The role of ecological opportunity in shaping host-parasite networks.

abstract：:This study reports that inhibition of Leishmania Topo-I with the minor groove-binding ligands (MGBLs) Hoechst 33342 (Ho342) blocks parasite growth in culture by mechanisms involving DNA breakage. While Ho342 inhibited the replication of several species of Leishmania in a dose- and time-dependent manner, Ho258 was not ...

journal_title：Parasitology

authors： Marquis JF,Drolet M,Olivier M

更新日期：2003-01-01 00:00:00

abstract：:Artificially transformed schistosomula of Schistosoma mansoni develop a consistent but small protection against the lethal effects of antibody plus complement when cultured for 24 h in a chemically defined medium. In contrast, they become rapidly resistant to antibody plus complement, when cultured in the presence of ...

journal_title：Parasitology

authors： Tavares CA,Soares RC,Coelho PM,Gazzinelli G

更新日期：1978-10-01 00:00:00

abstract：:Ticks are of vast medical and veterinary public health importance due to direct damage caused by feeding and their roles in transmitting well known and emerging infectious agents. Ticks and tick-borne pathogens stimulate the immune system of the host. Those immune interactions are of importance in tick biology, pathog...

journal_title：Parasitology

authors： Brossard M,Wikel SK

更新日期：2004-01-01 00:00:00

abstract：:The biodiversity of Trypanosoma cruzi is one of the main factors complicating the understanding of its molecular epidemiology. As an alternative to classical genetic methods, investigators have used DNA-mediated transformation techniques to study this diversity. Recently, transient expression data were shown to correl...

journal_title：Parasitology

authors： Laurent JP,Swindle J

更新日期：1999-12-01 00:00:00

abstract：:Feulgen-pararosaniline (SO2) staining was performed on stages in the life-cycle of Isospora (Toxoplasma) gondii, Eimeria tenella, Sarcocystis cruzi and Plasmodium berghei. The fluorescence emission of the stained DNA in nuclei of these stages was examined and compared with absorption microscopy measurements at 560 nm ...

journal_title：Parasitology

authors： Cornelissen AW,Overdulve JP,Van der Ploeg M

更新日期：1984-02-01 00:00:00

abstract：:Polychromophilus murinus, a malaria parasite of Chiroptera is reported from Myotis daubentoni in England. The vector was suspected to be the ectoparasitic Nycteribiid fly, Nycteribia kolenatii. N. kolenatii collected from wild-caught M. daubentoni were found to have oocysts on the midgut and sporozoites in the salivar...

journal_title：Parasitology

authors： Gardner RA,Molyneux DH

更新日期：1988-06-01 00:00:00

abstract：:Host-parasite interactions are shaped by the co-evolutionary arms race of parasite virulence, transmission success as well as host resistance and recovery. The virulence and fitness of parasites may depend on host condition, which is mediated, for instance, by host energy constraints. Here, we investigated to what ext...

journal_title：Parasitology

authors： Coors A,De Meester L

更新日期：2011-01-01 00:00:00

abstract：:Trichinella spiralis larvae infect and develop within skeletal muscle cells causing major changes to their mechanical properties. The aim of this investigation was to determine the effects of T. spiralis on the power output and fatigue resistance of the mammalian diaphragm under conditions simulating in vivo operation...

journal_title：Parasitology

authors： Harwood CL,Young IS,Lee DL,Altringham JD

更新日期：1996-12-01 00:00:00

abstract：:Electrophysiological and pharmacological techniques were used to study glutamatergic signalling in the parasitic nematode, Ascaris suum. Glutamate or kainate injections into whole worms produced a paralysed quasi-static posture similar to the waveform in behaving worms. The DE2 motorneuron class is a primary target. S...

journal_title：Parasitology

authors： Davis RE

更新日期：1998-05-01 00:00:00

abstract：:An immunochromatographic test (ICT), using recombinant truncated P50 (P50t), for the detection of antibodies to Babesia gibsoni was developed and evaluated. Whereas all sera from specific pathogen-free dogs were clearly negative, all sera from dogs experimentally infected with B. gibsoni were clearly positive in the I...

journal_title：Parasitology

authors： Verdida RA,Xuan X,Fukumoto S,Huang X,Zhou J,Igarashi I,Claveria FG,Nagasawa H

更新日期：2005-12-01 00:00:00

abstract：:Ornithodoros moubata ticks were fed on blood infected with Babesia equi. However, the parasites were quickly cleared as evidenced by the disappearance of B. equi-specific ribosomal RNA from the ticks. We hypothesized that if the Babesia parasite can escape midgut-associated barriers a non-vector tick can become infect...

journal_title：Parasitology

authors： Battsetseg B,Matsuo T,Xuan X,Boldbaatar D,Chee SH,Umemiya R,Sakaguchi T,Hatta T,Zhou J,Verdida AR,Taylor D,Fujisaki K

更新日期：2007-01-01 00:00:00

abstract：:Cystic echinococcosis (CE) is a high prevalence zoonosis among the rural population of Tacuarembó (Uruguay). The correlation between serological data and the incidence of risk factors was studied in a survey carried out in 1998 among rural communities where 480 individuals were examined by means of abdominal sonograph...

journal_title：Parasitology

authors： Hernández A,Cardozo G,Dematteis S,Baz A,Trias N,Nuñez H,Barragué A,López L,Fuentes J,López O,Ferreira C

更新日期：2005-04-01 00:00:00

abstract：:Infection of small macropodids with the larval stage of Echinococcus granulosus can cause fatalities as well as significant pulmonary impairment and other adverse sequelae. The brush-tailed rock-wallaby (Petrogale penicillata) is a small macropodid listed as vulnerable on the IUCN's Red List of Threatened Species. Thi...

journal_title：Parasitology

authors： Barnes TS,Goldizen AW,Morton JM,Coleman GT

更新日期：2008-05-01 00:00:00

abstract：:Murine monoclonal antibodies (mAbs) against Neospora caninum tachyzoites were produced to identify the cross-reactive antigens between N. caninum and Toxoplasma gondii. Ten mAbs recognizing cross-reactive antigens of both parasites were obtained and tentatively classified into 6 different groups based on their reactiv...

journal_title：Parasitology

authors： Liao M,Xuan X,Huang X,Shirafuji H,Fukumoto S,Hirata H,Suzuki H,Fujisaki K

更新日期：2005-05-01 00:00:00

abstract：:The glycogen stores of adult Schistosoma mansoni worms could be labelled by incubation of the worms, after an initial reduction of their glycogen content, in the presence of [6-14C]glucose. Subsequent breakdown of the labelled glycogen by the parasite revealed that glycogen was degraded to lactate and carbon dioxide. ...

journal_title：Parasitology

authors： Tielens AG,Celik C,Van den Heuvel JM,Elfring RH,Van den Bergh SG

更新日期：1989-02-01 00:00:00

abstract：:Theileria annulata infects and reversibly transforms bovine leucocytes. The parasite-transformed cells are immortalized, metastatic and express a number of metalloproteinases including matrix metalloproteinase 9 which they secrete. All the metalloproteinases observed on substrate gels are inhibited by tissue inhibitor...

journal_title：Parasitology

authors： Adamson RE,Hall FR

更新日期：1996-11-01 00:00:00

abstract：:The response of the plant parasitic nematode, Meloidogyne incognita (J2 stage) to avermectin B2a-23-one is triphasic, comprising an initial loss of locomotor activity where the juveniles remain sensitive to touch, a recovery phase and a final loss of activity where the juveniles are relatively insensitive to touch. In...

journal_title：Parasitology

authors： Wright DJ,Birtle AJ,Roberts IT

更新日期：1984-04-01 00:00:00

abstract：:Vesiculated protoscoleces (VP) were produced by culturing freshly collected protoscoleces from Echinococcus granulosus horse liver hydatids in RPMI 1640 monophasic medium at 37 degrees C for 18 days. Half of the VP were used as such, the other half used after killing them by freeze-thawing. Nine-day-old chicken heart ...

journal_title：Parasitology

authors： Janssen D,De Rycke PH,De Ridder L

更新日期：1990-06-01 00:00:00

abstract：:The epidemiological and ecological processes which govern the success of multiple-species co-infections are as yet unresolved. Here we investigated prior versus late residency within hosts, meaning which parasite contacts the host first, to determine if the outcomes of intra-host competition are altered. We infected a...

journal_title：Parasitology

authors： Lohr JN,Yin M,Wolinska J

更新日期：2010-09-01 00:00:00

abstract：:Part of Robert T. Leiper's (1881-1969) lasting legacy in medical helminthology is grounded on his pioneering work on schistosomiasis (Bilharzia). Having undertaken many expeditions to the tropics, his fascination with parasite life cycles typically allowed him to devise simple preventive measures that curtailed transm...

journal_title：Parasitology

authors： Stothard JR,Kabatereine NB,Archer J,Al-Shehri H,Tchuem-Tchuenté LA,Gyapong M,Bustinduy AL

更新日期：2017-10-01 00:00:00

abstract：:Sequence comparisons have recently shown that the Schistosoma mansoni protein Sm32 is similar to asparaginyl endoproteinases, a novel family of cysteine proteinases, of which the legumains from legumes are the best characterized. By synthesizing and employing fluorogenic peptide substrates for the specific detection o...

journal_title：Parasitology

authors： Dalton JP,Hola-Jamriska L,Brindley PJ

更新日期：1995-12-01 00:00:00

abstract：:In an experiment to study the infectivity, growth and virulence of Schistocephalus solidus in their first intermediate host, copepods of the species Macrocyclops albidus were kept singly and exposed to up to 9 coracidia. Eleven or 14 days post-infection (p.i.) the presence and growth of the cestode larvae relative to ...

journal_title：Parasitology

authors： Wedekind C

更新日期：1997-09-01 00:00:00

abstract：:Sex ratio theory posits that the adaptive proportion of male to female gametocytes of a malaria parasite within the vertebrate host depends on the degree of inbreeding within the vector. Gametocyte sex ratio could be phenotypically flexible, being altered based on the infection's clonal diversity, and thus likely inbr...

journal_title：Parasitology

authors： Osgood SM,Schall JJ

更新日期：2004-01-01 00:00:00

abstract：:To test the homogeneity of 18S sequences within Trypanosoma cruzi, riboprint profiles were separated by temperature gradient gel electrophoresis (TGGE). Upon interpretation of melting curves of fragments within a riboprint profile, there appeared to be two 18S sequence types within each stock examined. Two similar typ...

journal_title：Parasitology

authors： Stothard JR,Frame IA,Carrasco HJ,Miles MA

更新日期：1998-09-01 00:00:00

abstract：:Many different drug-resistant lines of rodent malaria are available as screening models. It is obligatory to screen new compounds for antimalarial activity against a series of resistant lines in order to identify a compound with potential for the treatment of multi-drug resistant (MDR) malaria infections. Instead of u...

journal_title：Parasitology

authors： Tripathi R,Dhawan S,Dutta GP

更新日期：2005-09-01 00:00:00

abstract：:The rapid elimination of the intestinal phase of Trichinella spiralis in NIH mice is associated with progressive inflammation of the intestinal tract. The non-specific effects of this inflammation were studied in mice concurrently infected with an unrelated parasite, Hymenolepis diminuta, which does not stimulate a vi...

journal_title：Parasitology

authors： Behnke JM,Bland PW,Wakelin D

更新日期：1977-08-01 00:00:00

abstract：:Cells of Leishmania donovani in co-culture with Trypanosoma brucei, were severely affected in their growth, resulting in swelling and subsequent lysis. Similar effects were also observed when Crithidia luciliae or Phytomonas sp. were co-cultured with T. brucei. Direct contact between the cells under investigation and ...

journal_title：Parasitology

authors： Coppens I,Ter Kuile BH,Opperdoes FR

更新日期：1992-12-01 00:00:00

abstract：:The surface morphology of fixed ovarian balls from female Moniliformis dubius, agd 12, 18, 26, 28, 42, 77, 105 and 118 days, has been examined by means of scanning electron microscopy. The appearance of the surface has been found to be variable between ovarian balls from worms of the same and different ages. Some part...

journal_title：Parasitology

authors： Parshad VR,Crompton DW,Martin J

更新日期：1980-10-01 00:00:00

abstract：:Exponential decay in community similarity as a function of distance is a ubiquitous phenomenon in biogeography. Thus, for parasite communities, pairwise similarity decreases with increasing geographical distance between host populations. This biogeographical rule should also apply along other dimensions characterizing...

journal_title：Parasitology

authors： Poulin R

更新日期：2010-04-01 00:00:00

abstract：:Confocal scanning laser microscopy has been employed with immunocytochemical techniques to map the distribution of serotoninergic and peptidergic components in the nervous system of the monogenean gill-parasite, Diclidophora merlangi; results are compared with the distribution of cholinergic components, following hist...

journal_title：Parasitology

authors： Maule AG,Halton DW,Johnston CF,Shaw C,Fairweather I

更新日期：1990-04-01 00:00:00