Abstract:
:Cells of Leishmania donovani in co-culture with Trypanosoma brucei, were severely affected in their growth, resulting in swelling and subsequent lysis. Similar effects were also observed when Crithidia luciliae or Phytomonas sp. were co-cultured with T. brucei. Direct contact between the cells under investigation and T. brucei was necessary because T. brucei did not hamper the growth of the other trypanosomatids, when separated by a filter with 0.2 microns pore size. Examination of this phenomenon at the ultrastructural level, in a co-culture of L. donovani and T. brucei, suggests that the plasma membrane permeability is increased in the former, as a result of a close cellular contact between the two cell types.
journal_name
Parasitologyjournal_title
Parasitologyauthors
Coppens I,Ter Kuile BH,Opperdoes FRdoi
10.1017/s0031182000074564subject
Has Abstractpub_date
1992-12-01 00:00:00pages
393-8eissn
0031-1820issn
1469-8161journal_volume
105 ( Pt 3)pub_type
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