Abstract:
:The present study was undertaken to investigate the antiparasitic activity of extracellular products of Streptomyces albus. Bioactivity-guided isolation of chloroform extracts affording a compound showing potent activity. The structure of the compound was elucidated as salinomycin (SAL) by EI-MS, 1H NMR and 13C NMR. In vitro test showed that SAL has potent anti-parasitic efficacy against theronts of Ichthyophthirius multifiliis with 10 min, 1, 2, 3 and 4 h (effective concentration) EC50 (95% confidence intervals) of 2.12 (2.22-2.02), 1.93 (1.98-1.88), 1.42 (1.47-1.37), 1.35 (1.41-1.31) and 1.11 (1.21-1.01) mg L-1. In vitro antiparasitic assays revealed that SAL could be 100% effective against I. multifiliis encysted tomonts at a concentration of 8.0 mg L-1. In vivo test demonstrated that the number of I. multifiliis trophonts on Erythroculter ilishaeformis treated with SAL was markedly lower than that of control group at 10 days after exposed to theronts (P < 0.05). In the control group, 80% mortality was observed owing to heavy I. multifiliis infection at 10 days. On the other hand, only 30.0% mortality was recorded in the group treated with 8.0 mg L-1 SAL. The median lethal dose (LD50) of SAL for E. ilishaeformis was 32.9 mg L-1.
journal_name
Parasitologyjournal_title
Parasitologyauthors
Yao JY,Gao MY,Jia YY,Wu YX,Yin WL,Cao Z,Yang GL,Huang HB,Wang CF,Shen JY,Gu ZMdoi
10.1017/S0031182018001919subject
Has Abstractpub_date
2019-04-01 00:00:00pages
521-526issue
4eissn
0031-1820issn
1469-8161pii
S0031182018001919journal_volume
146pub_type
杂志文章相关文献
PARASITOLOGY文献大全abstract::A delayed gamma distribution satisfactorily described the distribution of times to hatching of Ostertagia circumcincta eggs incubated in 0.1% saline at temperatures between 6 and 20 degrees C. Below 6 degree C hatching of eggs was extremely variable. The relationship between rates of development and temperature within...
journal_title:Parasitology
pub_type: 杂志文章
doi:10.1017/s0031182000061874
更新日期:1980-12-01 00:00:00
abstract::The molecular phylogeny and morphology of the oxyuroid nematode genus Aspiculuris from voles and house mice has been examined. Worms collected from Myodes glareolus in Poland, Eire and the UK are identified as Aspiculuris tianjinensis, previously known only from China, while worms from Mus musculus from a range of loc...
journal_title:Parasitology
pub_type: 杂志文章
doi:10.1017/S0031182015000864
更新日期:2015-10-01 00:00:00
abstract::Host-parasite interactions are shaped by the co-evolutionary arms race of parasite virulence, transmission success as well as host resistance and recovery. The virulence and fitness of parasites may depend on host condition, which is mediated, for instance, by host energy constraints. Here, we investigated to what ext...
journal_title:Parasitology
pub_type: 杂志文章
doi:10.1017/S0031182010000995
更新日期:2011-01-01 00:00:00
abstract::The abundance of Profilicollis botulus was monitored in eider ducks for 3 years. No significant difference in P. botulus abundance was found between eiders taken alive and those collected dead from the shore line, or between adult males and adult females. Adult male eiders had a seasonal pattern of infection. Incubati...
journal_title:Parasitology
pub_type: 杂志文章
doi:10.1017/s0031182000062806
更新日期:1985-12-01 00:00:00
abstract::Blastocystis SSU-rDNA sequence data from 317 captive and free-living non-human primates (NHPs) representing 30 genera of apes, Old and New World (OW and NW) monkeys and prosimians were analysed to investigate subtype (ST) and allele distribution among hosts. Excluding 20 mixed ST infections, 27% of the sequences belon...
journal_title:Parasitology
pub_type: 杂志文章
doi:10.1017/S0031182013000255
更新日期:2013-07-01 00:00:00
abstract::Isolates of Trypanosoma cruzi from human patients, domestic and sylvatic animals and vector insects were obtained in different areas of Argentina. Electrophoretic patterns of enzymes from extracts of 95 isolates were analysed. On the basis of zymograms providing information on 10 loci, 12 zymodemes are described accor...
journal_title:Parasitology
pub_type: 杂志文章
doi:10.1017/s0031182000067755
更新日期:1993-11-01 00:00:00
abstract::The individual and combined effects of cadmium (Cd) and 3,3',4,4',5-pentachlorobiphenyl (PCB 126) on the antibody response of fish against metazoan parasites were tested. Eels experimentally infected with the swim bladder nematode Anguillicola crassus were exposed to sublethal concentrations of Cd and PCB 126. Cd was ...
journal_title:Parasitology
pub_type: 杂志文章
doi:10.1017/s003118200300475x
更新日期:2004-04-01 00:00:00
abstract::Aspects of vitellogenesis, known to be controlled by juvenile hormone, are adversely affected by Hymenolepis diminuta infection of Tenebrio molitor, in spite of circulating titres of the hormone remaining unchanged. It has therefore been proposed that juvenile hormone binding is disrupted at the tissue site level. Juv...
journal_title:Parasitology
pub_type: 杂志文章
doi:10.1017/s0031182000065288
更新日期:1995-06-01 00:00:00
abstract::We have determined the molar content of guanine + cytosine (GC content) of DNA of the filarial nematode (Brugia malayi, Brugia pahangi and Dirofilaria imitis) and of the free-living soil nematodes Caenorhabditis elegans and have analysed the DNA for the presence of methylcytosine. Two independent methods, thermal dena...
journal_title:Parasitology
pub_type: 杂志文章
doi:10.1017/s0031182000066750
更新日期:1988-08-01 00:00:00
abstract::Recent studies of Echinococcus granulosus molecular strain typing have enabled a better understanding of the transmission cycle of cystic echinococcosis. There have been many publications in this area but there is a need for the evaluation of these tools. We have attempted to respond to this need in our study, which a...
journal_title:Parasitology
pub_type: 杂志文章
doi:10.1017/s0031182003004359
更新日期:2004-02-01 00:00:00
abstract::Most human cases of cryptosporidiosis are caused by Cryptosporidium parvum or Cryptosporidium hominis, but the use of molecular diagnostic methods has revealed that several other less common species or genotypes can also be involved. Here, we describe two unusual causes of cryptosporidiosis, one being the recently des...
journal_title:Parasitology
pub_type: 杂志文章
doi:10.1017/S003118201300084X
更新日期:2013-12-01 00:00:00
abstract::High levels of molecular diversity were identified in mitochondrial cytochrome c oxidase (cox1) gene sequences of Schistosoma turkestanicum from Hungary. These cox1 sequences were all specific to Hungary which contrasted with the low levels of diversity seen in the nuclear internal transcribed spacer region (ITS) sequ...
journal_title:Parasitology
pub_type: 杂志文章
doi:10.1017/S0031182017000920
更新日期:2017-11-01 00:00:00
abstract::Eimerian oocysts were found in 98% of 422 faeces samples from goats in SE England. It was found that 74% of the samples contained thousands or tens of thousands of oocysts/g. Kids less than 1 year old had higher oocyst counts than yearling or adult goats. Nine species of Eimeria were identified, and 65% of the samples...
journal_title:Parasitology
pub_type: 杂志文章
doi:10.1017/s0031182000064052
更新日期:1986-04-01 00:00:00
abstract::The flatworm nervous system employs a wide repertoire of neuroactive substances, including small chemical messengers, the so called classical transmitters, and several types of neuropeptides. A large body of research accumulated over four decades has provided a wealth of information on the tissue localization and effe...
journal_title:Parasitology
pub_type: 杂志文章,评审
doi:10.1017/S0031182005008565
更新日期:2005-01-01 00:00:00
abstract::There is increasing support for the presence of viruses and virus-like particles inside protozoan cells. This study describes viral-like RNA molecules that have been detected in two species of Eimeria that infect the chicken. The RNA molecule identified in E. maxima has been characterized: subcellular fractionation st...
journal_title:Parasitology
pub_type: 杂志文章
doi:10.1017/s0031182000063198
更新日期:1990-10-01 00:00:00
abstract::Cercariae of the bird schistosome Trichobilharzia regenti and of the human schistosome Schistosoma mansoni employ proteases to invade the skin of their definitive hosts. To investigate whether a similar proteolytic mechanism is used by both species, cercarial extracts of T. regenti and S. mansoni were biochemically ch...
journal_title:Parasitology
pub_type: 杂志文章
doi:10.1017/S0031182007002910
更新日期:2007-10-01 00:00:00
abstract::Toxocariasis is a common helminthic infection that has a worldwide distribution. However, data from Lebanon about the prevalence of this infection are non-existent. We conducted a Toxocara seroprevalence study with 150 subjects attending the outpatient clinics at the American University of Beirut Medical Center betwee...
journal_title:Parasitology
pub_type: 杂志文章
doi:10.1017/S0031182005009637
更新日期:2006-05-01 00:00:00
abstract::An ultrastructural study has been performed on radiation-attenuated parasites fixed in situ during their extended stay in the lungs. At day 7 post-infection all parasites were located within blood vessels. In contrast to normally migrating parasites, at days 13 and 21 post-infection the majority of radiation-attenuate...
journal_title:Parasitology
pub_type: 杂志文章
doi:10.1017/s0031182000056547
更新日期:1985-08-01 00:00:00
abstract::Trypanosomes are blood-borne parasites that can infect a variety of different vertebrates, including animals and humans. This study aims to broaden scientific knowledge about the presence and biodiversity of trypanosomes in Australian bats. Molecular and morphological analysis was performed on 86 blood samples collect...
journal_title:Parasitology
pub_type: 杂志文章
doi:10.1017/S0031182020001845
更新日期:2020-12-01 00:00:00
abstract::Two cDNAs encoding cysteine proteinases were isolated from a cDNA library constructed from feeding females of Heterodera glycines. The library was screened with a cysteine proteinase gene fragment originally amplified from cDNA of H. glycines. Database searches predict that 1 cDNA (hgcp-I) encodes a cathepsin L-like p...
journal_title:Parasitology
pub_type: 杂志文章
doi:
更新日期:1997-06-01 00:00:00
abstract::In areas where malaria is endemic, helminthic infections, caused by intestinal or filarial parasites, commonly coexist with malaria in the same individual. This study investigates the course of Plasmodium berghei malaria infection in CBA/J mice inoculated with irradiated attenuated 3rd-stage larvae (L3) of Brugia paha...
journal_title:Parasitology
pub_type: 杂志文章
doi:10.1017/s0031182096008566
更新日期:1997-04-01 00:00:00
abstract::Resistance to diclazuril was induced by 10 passages of the Houghton strains of Eimeria acervulina and E. tenella in chickens given progressively greater concentrations of the drug. This resistance was, however, not complete since the drug retained some efficacy against the drug-passaged lines. Attempts to passage the ...
journal_title:Parasitology
pub_type: 杂志文章
doi:10.1017/s0031182000058625
更新日期:1989-10-01 00:00:00
abstract::Infection with the endosymbiotic bacteria Wolbachia is widespread in filarial nematodes. Previous studies have suggested concordance between the phylogeny of Wolbachia with that of their nematode hosts. However, there is only one published molecular phylogenetic study of filarial species, based on the 5S rRNA gene spa...
journal_title:Parasitology
pub_type: 杂志文章
doi:10.1017/s0031182000007149
更新日期:2001-01-01 00:00:00
abstract::Studies of the kinetics of adenosine transport were carried out on the P1 and P2 transporters of drug-sensitive Trypanosoma evansi and its cloned derivative, resistant to the melaminophenyl arsenical Mel CY. Characterization of adenosine uptake was made by estimation of the maximum concentration taken up at time infin...
journal_title:Parasitology
pub_type: 杂志文章
doi:10.1017/s003118200300413x
更新日期:2003-12-01 00:00:00
abstract::The surface morphology of fixed ovarian balls from female Moniliformis dubius, agd 12, 18, 26, 28, 42, 77, 105 and 118 days, has been examined by means of scanning electron microscopy. The appearance of the surface has been found to be variable between ovarian balls from worms of the same and different ages. Some part...
journal_title:Parasitology
pub_type: 杂志文章
doi:10.1017/s0031182000056146
更新日期:1980-10-01 00:00:00
abstract::Cells of Leishmania donovani in co-culture with Trypanosoma brucei, were severely affected in their growth, resulting in swelling and subsequent lysis. Similar effects were also observed when Crithidia luciliae or Phytomonas sp. were co-cultured with T. brucei. Direct contact between the cells under investigation and ...
journal_title:Parasitology
pub_type: 杂志文章
doi:10.1017/s0031182000074564
更新日期:1992-12-01 00:00:00
abstract::Antigenic differences between intra-lymphocytic theilerial parasites isolated from the blood of 18 African buffalo and grown in vitro were assessed with anti-schizont monoclonal antibodies (mAbs). There was marked antigenic diversity both between isolates from different buffalo and between isolates taken at different ...
journal_title:Parasitology
pub_type: 杂志文章
doi:10.1017/s0031182000055761
更新日期:1987-06-01 00:00:00
abstract::Essential oils (EOs) are considered a new class of ecological products aimed at the control of insects for industrial and domestic use; however, there still is a lack of studies involving the control of fleas. Ctenocephalides felis felis, the most observed parasite in dogs and cats, is associated with several diseases...
journal_title:Parasitology
pub_type: 杂志文章
doi:10.1017/S0031182019001641
更新日期:2020-03-01 00:00:00
abstract::Leishmania are obligatory intracellular parasitic protozoa that cycle between sand fly mid-gut and phagolysosomes of mammalian macrophages. They have developed genetically programmed changes in gene and protein expression that enable rapid optimization of cell function according to vector and host environments. During...
journal_title:Parasitology
pub_type: 杂志文章,评审
doi:10.1017/S0031182012000157
更新日期:2012-08-01 00:00:00
abstract::Costa Rica is near malaria elimination. This achievement has followed shifts in malaria health policy. Here, we evaluate the impacts that different health policies have had on malaria transmission in Costa Rica from 1913 to 2018. We identified regime shifts and used regression models to measure the impact of different...
journal_title:Parasitology
pub_type: 杂志文章
doi:10.1017/S0031182020000621
更新日期:2020-08-01 00:00:00