Consequence of Hoechst 33342-mediated Leishmania DNA topoisomerase-I inhibition on parasite replication.

abstract：:A delayed gamma distribution satisfactorily described the distribution of times to hatching of Ostertagia circumcincta eggs incubated in 0.1% saline at temperatures between 6 and 20 degrees C. Below 6 degree C hatching of eggs was extremely variable. The relationship between rates of development and temperature within...

journal_title：Parasitology

authors： Young RR,Anderson N,Overend D,Tweedie RL,Malafant KW,Preston GA

更新日期：1980-12-01 00:00:00

abstract：:Leishmania donovani causes visceral disease (kala-azar), a major health problem throughout the tropics with 500 000 new cases every year. Leishmania differentiates from the promastigote to the amastigote form to establish infection in a mammalian host. To understand the process of differentiation, we assessed the glob...

journal_title：Parasitology

authors： Srividya G,Duncan R,Sharma P,Raju BV,Nakhasi HL,Salotra P

更新日期：2007-10-01 00:00:00

abstract：:The isolation of 2 genomic clones has allowed us to further characterize a Schistosoma mansoni serine protease designated SmSP1. The deduced amino acid sequence (248aa) considered as a 'light chain' encoding the active site, presents significant homologies with mouse plasma kallikrein and human factor I light chain. T...

journal_title：Parasitology

authors： Cocude C,Pierrot C,Cêtre C,Fontaine J,Godin C,Capron A,Khalife J

更新日期：1999-04-01 00:00:00

abstract：:BALB/c mice were characterized as more resistant to infection with Heligmosomoides polygyrus (Nematoda) than C57BL/6 mice based on lower establishment and survival during a primary infection and stronger protection induced by an immunizing regime. It was hypothesized, therefore, that C57BL/6 mice would be more heavily...

journal_title：Parasitology

authors： Scott ME

更新日期：1991-12-01 00:00:00

abstract：:Differentiation of epimastigotes and production of infective metacyclic forms of Trypanosoma congolense were examined in a culture system which enabled manipulation of the population density of insect forms. Scanning electron microscopy of cultures revealed the attachment sites of epimastigotes in detail, showing them...

journal_title：Parasitology

authors： Prain CJ,Ross CA

更新日期：1990-02-01 00:00:00

abstract：:Acute Chagas disease outbreaks are related to the consumption of food or drink contaminated by triatomine feces, thus making oral infection an important route of transmission. Both vector-borne and oral infections trigger important cardiac manifestations in the host that are related to a dysregulated immune response. ...

journal_title：Parasitology

authors： Kuehn CC,Oliveira LG,Miranda MA,Prado JC

更新日期：2014-06-01 00:00:00

abstract：:If parasitic infection is a driving force in female mate choice, then females should preferentially select parasite-free males. The role of infection on female mate choice in mammals was assessed using a 3-chambered apparatus. A female CD-1 mouse was allowed to choose between 2 tethered male mice, 1 uninfected and 1 i...

journal_title：Parasitology

authors： Ehman KD,Scott ME

更新日期：2002-11-01 00:00:00

abstract：:Toxoplasma gondii has a unique enzyme, a NTPase, which has a wide specificity toward NTP. In the present study, we produced a monoclonal antibody (IgG1, 6C6) against the enzyme which could recognize NTPase isozymes among several strains of T. gondii. Three avirulent strains of T. gondii, ME49, Beverley and Nakayama, w...

journal_title：Parasitology

authors： Kikuchi T,Furuta T,Kojima S

更新日期：2001-01-01 00:00:00

abstract：:Interferon-gamma (IFN-gamma) has a crucial role for host defence against parasite infection. It is not clear, however, how IFN-gamma affects the parasite-infected host cells. The effect of IFN-gamma on Neospora caninum-infected cells was investigated in murine fibroblasts and canine kidney cells in vitro. In the prese...

journal_title：Parasitology

authors： Nishikawa Y,Mishima M,Nagasawa H,Igarashi I,Fujisaki K,Otsuka H,Mikami T

更新日期：2001-07-01 00:00:00

abstract：:Post-mesocyclic development of Trypanosoma brucei in the tsetse fly in its migration from midgut to salivary glands, was revisited by sequential microdissection, morphometry and DNA-cytofluorometry. This development started by day 6 after the infective feed, with passage of mesocyclic midgut trypomastigotes through pr...

journal_title：Parasitology

authors： Van Den Abbeele J,Claes Y,van Bockstaele D,Le Ray D,Coosemans M

更新日期：1999-05-01 00:00:00

abstract：:A number of authors have demonstrated that the schistosomicidal compound, Praziquantel (Pzq), depends for its action upon the immune status of the host (Sabah et al. 1985; Brindley & Sher, 1987; Doenhoff et al. 1987). We have attempted to define the synergistic interaction between immuno- and chemotherapy further, usi...

journal_title：Parasitology

authors： Piper KP,Mott RF,Hockley DJ,McLaren DJ

更新日期：1991-10-01 00:00:00

abstract：:RNA extracted from purified parasites of Plasmodium knowlesi was fractionated using agarose gel electrophoresis. Preparations from para sites grown both in vivo and in vitro contained species of RNA with sedimentation coefficients of 4-0S, 5-0S, 16-6S, 24-2S, 31-4S, 38-0S and 48-3S. There was less RNA present in paras...

journal_title：Parasitology

authors： Trigg PI,Shakespeare PG,Burt SJ,Kyd SI

更新日期：1975-10-01 00:00:00

abstract：:West-central China is an important endemic focus of both alveolar and cystic echinococcosis where several species of intermediate host are commonly infected with Echinococcus granulosus and E. multilocularis . Isolates of E. granulosus were collected from humans and other animals from different geographical areas of Q...

journal_title：Parasitology

authors： Yang YR,Rosenzvit MC,Zhang LH,Zhang JZ,McManus DP

更新日期：2005-10-01 00:00:00

abstract：:The extent of sequence diversity among the genes encoding 10 antigens (Tp1-10) known to be recognized by CD8+ T lymphocytes from cattle immune to Theileria parva was analysed. The sequences were derived from parasites in 23 buffalo-derived cell lines, three cattle-derived isolates and one cloned cell line obtained fro...

journal_title：Parasitology

authors： Sitt T,Pelle R,Chepkwony M,Morrison WI,Toye P

更新日期：2018-09-01 00:00:00

abstract：:Endosymbiotic bacteria of the genus Wolbachia infect a number of invertebrate species in which they induce various alterations in host reproduction, mainly cytoplasmic incompatibility (CI). In contrast to most other maternally transmitted parasites, manipulation of host reproduction makes the spread of Wolbachia possi...

journal_title：Parasitology

authors： Fleury F,Vavre F,Ris N,Fouillet P,Boulétreau M

更新日期：2000-11-01 00:00:00

abstract：:Small vessels showing inflammatory cell infiltrates were invariably observed in the vicinity of intact Toxoplasma tissue cysts within the brains of mice congenitally infected with the protozoan. Lymphocytes were observed in intimate contact with the luminal aspect of the endothelium, penetrating into the thickened bas...

journal_title：Parasitology

authors： Sims TA,Hay J

更新日期：1995-02-01 00:00:00

abstract：:Anti-trypanosomiasis vaccination still remains the best theoretical option in the fight against a disease that is continuously hovering between its wildlife reservoir and its reservoir in man and livestock. While antigenic variation of the parasite surface coat has been considered the major obstacle in the development...

journal_title：Parasitology

authors： Magez S,Caljon G,Tran T,Stijlemans B,Radwanska M

更新日期：2010-12-01 00:00:00

abstract：:The 4-aminoquinolines chloroquine (CQ) and amodiaquine (AM) were used to treat Gambian children with uncomplicated falciparum malaria in a randomized drug trial. Blood samples were taken immediately before treatment (day 0), and at day 7 and day 28 after treatment. Samples from those parasitologically positive at day ...

journal_title：Parasitology

authors： Duraisingh MT,Drakeley CJ,Muller O,Bailey R,Snounou G,Targett GA,Greenwood BM,Warhurst DC

更新日期：1997-03-01 00:00:00

abstract：:The amitochondriate parasitic protist Trichomonas vaginalis can utilize either glucose or maltose as carbon and energy source. The mechanisms of maltose utilization were explored with uptake experiments using radio-isotope labelled maltose in combination with the silicone-oil centrifugation technique and enzymatic ass...

journal_title：Parasitology

authors： ter Kuile BH,Müller M

更新日期：1995-01-01 00:00:00

abstract：:In previous studies, ultrastructural observations revealed a large number of gap junctions (GJs) in the neck and immature proglottid tissues of Taenia solium tapeworms. In these helminths, cytoplasmic glycogen sacs are connected by numerous discrete GJs to other cells throughout the maturing strobilar tissue. Disconti...

journal_title：Parasitology

authors： Zurabian R,Landa A,Robert L,Willms K

更新日期：2008-08-01 00:00:00

abstract：:Amoebiasis, infection by the protozoan parasite Entamoeba histolytica, remains a global health problem, despite the availability of effective treatment. While improved sanitation could lead to the eradication of this disease, it is unlikely that this will occur worldwide in the foreseeable future; thus alternative mea...

journal_title：Parasitology

authors： Stanley SL Jr

更新日期：2006-01-01 00:00:00

abstract：:In this review, we envisage the host environment, not as a hostile one, since the schistosome thrives there, but as one in which the relationship between the two organisms consists of constant communication, through signalling mechanisms involving sense organs, surface glycocalyx, surface membrane and internal organs ...

journal_title：Parasitology

authors： Kusel JR,Al-Adhami BH,Doenhoff MJ

更新日期：2007-10-01 00:00:00

abstract：:Aiming to further characterize the haemocyte subsets in Biomphalaria snails, we have performed a detailed flow cytometric analysis of whole haemolymph cellular components using a multiparametric dual colour labelling procedure. Ethidium bromide/acridine orange fluorescence features were used to first select viable hae...

journal_title：Parasitology

authors： Martins-Souza RL,Pereira CA,Coelho PM,Martins-Filho OA,Negrão-Corrêa D

更新日期：2009-01-01 00:00:00

abstract：:The first rigorous proof applicable to the migration pathway of an infective juvenile macroparasite inside its host is presented. Third-stage larvae of a homogonic strain of Strongyloides ratti applied in exact doses of less than 20 to the skin of the flank of young rats were recovered 16-40 h later in the naso-fronta...

journal_title：Parasitology

authors： Tindall NR,Wilson PA

更新日期：1988-06-01 00:00:00

abstract：:The biological parameters which generate seasonal fluctuations in the size of populations of Caryophyllaeus laticeps are examined in detail. A mathematical model is formulated to describe the dynamics of the adult parasite within the fish host Abramis brama, and the predictions of the model are compared with observed ...

journal_title：Parasitology

authors： Anderson RM

更新日期：1976-06-01 00:00:00

abstract：:Syphacia stroma (von Linstow, 1884) Morgan, 1932 and Syphacia frederici Roman, 1945 are oxyurid nematodes that parasitize two murid rodents, Apodemus sylvaticus and Apodemus flavicollis, on the European mainland. Only S. stroma has been recorded previously in Apodemus spp. from the British Isles. Despite the paucity o...

journal_title：Parasitology

authors： Stewart A,Lowe A,Smales L,Bajer A,Bradley J,Dwużnik D,Franssen F,Griffith J,Stuart P,Turner C,Zaleśny G,Behnke JM

更新日期：2018-03-01 00:00:00

abstract：:Experiments to investigate the metabolism of glycine, L-glutamic acid and L-aspartic acid by Moniliformis moniliformis were carried out by incubating adult worms aerobically for 3 h at 37 degrees C in Tyrode's solution containing either [U-14C]glycine, L-[U-14C]glutamic acid, L-[U-14C]aspartic acid or L-[4-14C]asparti...

journal_title：Parasitology

authors： Ward PF,Crompton DW

更新日期：1987-06-01 00:00:00

abstract：:In order to study the effects of acclimatization of Plasmodium in beta-thalassaemic mice, we used a mouse model of beta-thalassaemia (DBA/2J/beta-thal/beta-thal), similar to that observed in humans. We acclimatized 3 rodent malarias (P. berghei, P. chabaudi and P. yoelii) in DBA/2J and DBA/2J/beta-thal mice lines, by ...

journal_title：Parasitology

authors： Clarebout G,Gamain B,Slomianny C,Camus D,Dive D

更新日期：1996-03-01 00:00:00

abstract：:Isolates of Trypanosoma cruzi from human patients, domestic and sylvatic animals and vector insects were obtained in different areas of Argentina. Electrophoretic patterns of enzymes from extracts of 95 isolates were analysed. On the basis of zymograms providing information on 10 loci, 12 zymodemes are described accor...

journal_title：Parasitology

authors： de Luca D'oro GM,Gardenal CN,Perret B,Crisci JV,Montamat EE

更新日期：1993-11-01 00:00:00

abstract：:The incidence of fever among infants in the village of Idete in the Morogoro region of Tanzania was analyzed in relation to densities of Plasmodium falciparum parasites in the peripheral blood. Parasite densities in both fever cases and in asymptomatic infants, were compared and a Bayesian non-parametric mixture decom...

journal_title：Parasitology

authors： Vounatsou P,Smith T,Kitua AY,Alonso PL,Tanner M

更新日期：2000-01-01 00:00:00