Identification of a developmentally regulated Schistosoma mansoni serine protease homologous to mouse plasma kallikrein and human factor I.

abstract：:Of the 7 genetic assemblages of the parasite Giardia duodenalis only 2 (A and B) are known to cause infections in humans. These assemblages have been characterized in detail at the genomic level but few studies have examined differences in the proteins expressed. Employing one and two-dimensional PAGE we have identifi...

journal_title：Parasitology

authors： Steuart RF,O'Handley R,Lipscombe RJ,Lock RA,Thompson RC

更新日期：2008-12-01 00:00:00

abstract：:Traditionally, the family Campulidae has been associated either with the family Fasciolidae, parasites of ruminants, or the Acanthocolpidae, parasites of fishes, based on morphological similarities. Since morphology does not seem to resolve clearly the problem of the relationships of campulids, we have used the sequen...

journal_title：Parasitology

authors： Fernandez M,Littlewood DT,Latorre A,Raga JA,Rollinson D

更新日期：1998-10-01 00:00:00

abstract：:Vesiculated protoscoleces (VP) were produced by culturing freshly collected protoscoleces from Echinococcus granulosus horse liver hydatids in RPMI 1640 monophasic medium at 37 degrees C for 18 days. Half of the VP were used as such, the other half used after killing them by freeze-thawing. Nine-day-old chicken heart ...

journal_title：Parasitology

authors： Janssen D,De Rycke PH,De Ridder L

更新日期：1990-06-01 00:00:00

abstract：:Cyst fluid (CF) of Taenia solium metacestode (TsM) is an important source of serodiagnostic antigens. We have investigated the molecular characteristics of the 120 kDa protein complex in TsM CF purified by fast performance liquid chromatography. The structure of the purified protein was characterized by a variety of p...

journal_title：Parasitology

authors： Lee EG,Bae YA,Jeong YT,Chung JY,Je EY,Kim SH,Na BK,Ju JW,Kim TS,Ma L,Cho SY,Kong Y

更新日期：2005-12-01 00:00:00

abstract：:Population genetics of multi-host pathogens offers great potential for the understanding of their complex epidemiology but care must be taken to ensure that the sampling procedure does not bias estimates of population indices. The transfer of material to laboratory passage, in particular, runs the risk of bottleneckin...

journal_title：Parasitology

authors： Shrivastava J,Gower CM,Balolong E Jr,Wang TP,Qian BZ,Webster JP

更新日期：2005-11-01 00:00:00

abstract：:Interferon-gamma (IFN-gamma) has a crucial role for host defence against parasite infection. It is not clear, however, how IFN-gamma affects the parasite-infected host cells. The effect of IFN-gamma on Neospora caninum-infected cells was investigated in murine fibroblasts and canine kidney cells in vitro. In the prese...

journal_title：Parasitology

authors： Nishikawa Y,Mishima M,Nagasawa H,Igarashi I,Fujisaki K,Otsuka H,Mikami T

更新日期：2001-07-01 00:00:00

abstract：:The response of the plant parasitic nematode, Meloidogyne incognita (J2 stage) to avermectin B2a-23-one is triphasic, comprising an initial loss of locomotor activity where the juveniles remain sensitive to touch, a recovery phase and a final loss of activity where the juveniles are relatively insensitive to touch. In...

journal_title：Parasitology

authors： Wright DJ,Birtle AJ,Roberts IT

更新日期：1984-04-01 00:00:00

abstract：:Malaria remains a major cause of human morbidity and mortality worldwide. Plasmodium falciparum, the most virulent of the 4 human Plasmodium species causing malaria, is potentially life threatening, is increasing in prevalence and is becoming even more resistant to in-use drugs. In light of the growing problem of mult...

journal_title：Parasitology

authors： Mahajan SS,Kamath VR,Ghatpande SS

更新日期：2005-10-01 00:00:00

abstract：:The levels of superoxide dismutase (SOD) were determined in detergent-soluble, somatic and excretion-secretion (E-S) preparations from adult Fasciola hepatica using the xanthine oxidase system and visualized in substrate gels. Compared to detergent-soluble and somatic extracts, E-S products showed the highest SOD acti...

journal_title：Parasitology

authors： Piacenza L,Radi R,Goñi F,Carmona C

更新日期：1998-12-01 00:00:00

abstract：:We investigated changes in the behaviour of Stagnicola elodes associated with the emergence of Plagiorchis elegans cercariae. Within 15 min of the reduction in light intensity, which triggered the onset of cercarial emergence, infected snails moved to the top of the water column and remained there for 2-3 h. Seventy-n...

journal_title：Parasitology

authors： Lowenberger CA,Rau ME

更新日期：1994-07-01 00:00:00

abstract：:The development and growth of Haemonchus contortus was studied in the stomach of the laboratory rabbit. Less than 1% of the ensheathed infective larvae given to rabbits became established, whereas after exsheathment in vitro under physiological conditions, 20-30% of the larvae administered developed to the 4th stage. ...

journal_title：Parasitology

authors： Mapes CJ,Gallie GJ

更新日期：1977-06-01 00:00:00

abstract：:Pelodera strongyloides larvae were found in the conjunctival sacs of Apodemus sylvaticus and Clethrionomys glareolus and in hair follicles of A. sylvaticus. Those in the eyes were 3rd-stage larvae while most of those in the dermis were early 4th stages. There was no evidence of pathology and sections of the skin showe...

journal_title：Parasitology

authors： Hominick WM,Aston AJ

更新日期：1981-08-01 00:00:00

abstract：:We have cloned a cDNA encoding a novel antigen from a Sarcoptes scabiei (Acari) cDNA library by immunoscreening with sera from S. scabiei-infected dogs. The antigen is encoded by a 2,157 bp mRNA with a predicted open reading frame of 719 amino acids (molecular weight 79 kDa). Our sequence analysis identified the prese...

journal_title：Parasitology

authors： Ljunggren EL,Bergström K,Morrison DA,Mattsson JG

更新日期：2006-01-01 00:00:00

abstract：:SIV rats infected with a high dose (50,000 oocysts) of Eimeria nieschulzi displayed clinical symptoms of coccidiosis such as diarrhoea (days 6 and 7 post-primary infection) and weight loss (days 6-8 post-primary infection) and were completely immune to challenge with a similar dose. The ability of rats to produce tumo...

journal_title：Parasitology

authors： Smith NC,Ovington KS,Deplazes P,Eckert J

更新日期：1995-07-01 00:00:00

abstract：:Patterns of genetic subdivision in parasite populations can provide important insights into transmission processes and complement information obtained using traditional epidemiological techniques. We describe mitochondrial sequence variation in 265 Ascaris collected from 62 individual hosts (humans and pigs) from 35 h...

journal_title：Parasitology

authors： Anderson TJ,Romero-Abal ME,Jaenike J

更新日期：1995-02-01 00:00:00

abstract：:Neurocysticercosis (NCC) is the most common parasitic disease of the central nervous system (CNS) caused by the larval form of the tapeworm Taenia solium. NCC has a long asymptomatic period with little or no inflammation, and the sequential progression to symptomatic NCC depends upon the intense inflammation associate...

journal_title：Parasitology

authors： Alvarez JI,Mishra BB,Gundra UM,Mishra PK,Teale JM

更新日期：2010-03-01 00:00:00

abstract：:An enzyme-linked immunosorbent assay (ELISA) was used to detect antibodies to Encephalitozoon cuniculi in man, using spores derived from tissue culture as antigen. Negligible cross-reactions were found with other microsporidia of vertebrate or of invertebrate origin and there was no cross-reaction with Toxoplasma gond...

journal_title：Parasitology

authors： Hollister WS,Canning EU

更新日期：1987-04-01 00:00:00

abstract：:Highly purified mitochondrial fractions have been isolated from the intraerythrocytic stages of two mammalian Plasmodium spp., Plasmodium yoelii of rodents and Plasmodium falciparum of man. Mitochondria of the former parasite are cristate whereas those of the latter are essentially acristate. Isolated mitochondria fro...

journal_title：Parasitology

authors： Fry M,Beesley JE

更新日期：1991-02-01 00:00:00

abstract：:Depending on the extent of evolutionary divergence among parent taxa, hybrids may suffer from a breakdown of co-adapted genes or may conversely exhibit vigour due to the heterosis effect, which confers advantages to increased genetic diversity. That last mechanism could explain the success of hybrids when hybridizatio...

journal_title：Parasitology

authors： Planade B,Lena JP,Li H,Plenet S,Guegan JF,Thomas F,Hurtrez-Bousses S,Renaud F,Joly P

更新日期：2009-08-01 00:00:00

abstract：:The glycolytic enzyme triosephosphate isomerase catalyses the isomerization between glyceraldehyde 3-phosphate and dihydroxyacetone phosphate. Here we report that Trichomonas vaginalis contains 2 fully functional tpi genes. Both genes are located in separated chromosomal context with different promoter regulatory elem...

journal_title：Parasitology

authors： Figueroa-Angulo EE,Estrella-Hernández P,Salgado-Lugo H,Ochoa-Leyva A,Gómez Puyou A,Campos SS,Montero-Moran G,Ortega-López J,Saab-Rincón G,Arroyo R,Benítez-Cardoza CG,Brieba LG

更新日期：2012-11-01 00:00:00

abstract：:Electrophoresis of secretions collected from Globodera pallida revealed a smeared region between 25 and 50 kDa, and a single band of < 20 kDa. The secretions were used to raise an antiserum (LW1). Immunoblotting of parasite homogenates with LW1 differentiated G. pallida from its sibling species G. rostochiensis and re...

journal_title：Parasitology

authors： Duncan LH,Robertson L,Robertson WM,Kusel JR

更新日期：1997-10-01 00:00:00

abstract：:n order to investigate the dynamics of Septin4 (Sept4) expression and its function in the formation of fibrotic livers in mice infected with Schistosoma japonicum, we constructed the mouse model of S. japonicum egg-induced liver fibrosis for 24 weeks. Immunohistochemical staining, qRT-PCR and Western blot were used to...

journal_title：Parasitology

authors： Duan YN,Qian HY,Qin YW,Zhu DD,He XX,Zhou Q,Yang YN,Bao J,Feng JR,Sun W,Chen JL

更新日期：2011-07-01 00:00:00

abstract：:Ligand-gated chloride channels (LGCCs) are key components of the nervous system of parasitic nematodes and important targets for anthelmintics. Here, we describe the isolation and characterization of a novel member of the LGCC gene family (HcLGCC1) from the parasitic nematode Haemonchus contortus. Sequence analysis re...

journal_title：Parasitology

authors： Forrester SG,Siddiqui SZ

更新日期：2008-04-01 00:00:00

abstract：:In situations where malaria eradication is not an option in the foreseeable future the emphasis must be on the control of morbidity and mortality due to malaria. Under such circumstances drawing a distinction between malarial parasitization and malarial disease may be important for workers in both field and laboratory...

journal_title：Parasitology

authors： Marsh K

更新日期：1992-01-01 00:00:00

abstract：:The serial passage of 3 strains of Eimeria from the chicken in embryonating turkey embryos is reported here. All 3 strains increased their reproduction in turkey embryos; reproduction being equal to or better than the same lines maintained in chicken embryos. Pathogenicity and immunogenicity trials conducted in chicke...

journal_title：Parasitology

authors： Kogut MH,Gore TC,Long PL

更新日期：1983-04-01 00:00:00

abstract：:Within the genus Cryptosporidium 2 lineages have evolved, one adapted to the acid environment of the stomach and abomasum, the other comprising parasites that multiply in the small intestine. We tested whether the release of sporozoites from oocysts, a process known as excystation, is triggered by conditions which mim...

journal_title：Parasitology

authors： Widmer G,Klein P,Bonilla R

更新日期：2007-10-01 00:00:00

abstract：:A double antibody sandwich ELISA technique has been developed for detection of antigens of African trypanosomes present in the sera of infected mammals. The assay uses a high titre, high affinity rabbit antiserum made to purified membranes of procyclic trypanosomes as "capture" reagent and a mixture of three biotin-la...

journal_title：Parasitology

authors： Liu MK,Pearson TW

更新日期：1987-10-01 00:00:00

abstract：:The genetic basis of virulence in a line (YM) of Plasmodium yoelii yoelii was investigated in a cross with a mild line (A/C). The blood forms of the virulent line developed extensively in mature erythrocytes of mice, causing death of the host within 7 days; infections with the mild line were normally restricted to ret...

journal_title：Parasitology

authors： Walliker D,Sanderson A,Yoeli M,Hargreaves BJ

更新日期：1976-04-01 00:00:00

abstract：:Cryptosporidia are important protozoan parasites of vertebrates, and a number of species and genotypes, with different host ranges, have been described. In this study a protocol was established for the detection and the genetic characterization of Cryptosporidium spp. isolated from various types of surface waters (riv...

journal_title：Parasitology

authors： Ward PI,Deplazes P,Regli W,Rinder H,Mathis A

更新日期：2002-04-01 00:00:00

abstract：:Why do parasites kill their hosts? During this past decade, research in three different areas; evolutionary ecology, medical microbiology, and population genetics has provided theory and data that address this and related questions of selection and the evolution and maintenance of parasite virulence. A general theory ...

journal_title：Parasitology

authors： Levin BR,Svanborg Edén C

更新日期：1990-01-01 00:00:00