Synergistic antimalarial activity of ketones with rufigallol and vitamin C.

abstract：:Like in other trypanosomatids D-glucose is a crucial source of energy to Trypanosoma rangeli, a non-pathogenic parasite that in Central and South America infects triatomine vectors and different mammalian species, including humans. In several trypanosome species, D-glucose transporters were already described and clone...

journal_title：Parasitology

authors： Miletti LC,Koerich LB,Pacheco LK,Steindel M,Stambuk BU

更新日期：2006-12-01 00:00:00

abstract：:A collection of stocks of Trypanosoma brucei rhodesiense isolated in Kenya have been examined for electrophoretic variation in 20 enzymes. The results obtained have been analysed in order to determine whether these trypanosomes are diploid and undergo mating and to determine the genetic distance between T. b. rhodesie...

journal_title：Parasitology

authors： Tait A,Barry JD,Wink R,Sanderson A,Crowe JS

更新日期：1985-02-01 00:00:00

abstract：:A dipstick dot ELISA for detection of Taenia-specific coproantigens was developed. The test was based on a sandwich ELISA using antibodies raised against adult Taenia solium. Antibodies were absorbed to nitrocellulose paper previously adhered to acetate plastic to form dipsticks. Once blocked with 5% skimmed milk and ...

journal_title：Parasitology

authors： Allan JC,Mencos F,Garcia-Noval J,Sarti E,Flisser A,Wang Y,Liu D,Craig PS

更新日期：1993-07-01 00:00:00

abstract：:Phylogenetic relationships among Trypanosoma rangeli isolates from man, wild mammals and triatomine bugs from widespread geographical origin were inferred by comparison of the small subunit of ribosomal gene sequences. The phylogenetic trees indicated that the subgenus Herpetosoma is polyphyletic and strongly supporte...

journal_title：Parasitology

authors： Da Silva FM,Noyes H,Campaner M,Junqueira AC,Coura JR,Añez N,Shaw JJ,Stevens JR,Teixeira MM

更新日期：2004-11-01 00:00:00

abstract：:Intact surface membrane vesicles were obtained and purified from the schistosomula of Schistosoma mansoni. The method of preparation of the vesicles involved treating the schistosomula in a buffered high salt medium for 1 h at 4 degrees C (Step 1), and then for 1 h at 25-37 degrees C (Step 2). Vesicles were formed fro...

journal_title：Parasitology

authors： Kusel JR,Gazzinelli G,Colley DG,de Souza CP,Cordeiro MN

更新日期：1984-12-01 00:00:00

abstract：:We investigated intestinal trichomonads in western lowland gorillas, central chimpanzees and humans cohabiting the forest ecosystem of Dzanga-Sangha Protected Area in Central African Republic, using the internal transcribed spacer (ITS) region and SSU rRNA gene sequences. Trichomonads belonging to the genus Tetratrich...

journal_title：Parasitology

authors： Petrželková KJ,Smejkalová P,Céza V,Pafčo B,Shutt-Phillips KA,Todd A,Jirků-Pomajbíková K,Benavides J,Modrý D,Čepička I

更新日期：2020-02-01 00:00:00

abstract：:Fractionation of Schistosoma mansoni cercariae gland secretion on a Sephadex G-150 column followed by a Superose-12 column in an FPLC system, isolated a 47 kDa protease which migrated as a single band on SDS-PAGE gels. A monoclonal antibody (MAb) was produced which recognizes only the 47 kDa protease, and an immuno-af...

journal_title：Parasitology

authors： Chavez-Olortegui C,Resende M,Tavares CA

更新日期：1992-10-01 00:00:00

abstract：:Schistosomiasis is a health problem in Brazil and the role of rodents in maintaining the schistosome life-cycle requires further clarification. The influence of Schistosoma mansoni on a population of Nectomys squamipes was studied by capture-recapture (1st phase, from June 1991 to November 1995) and removal (2nd phase...

journal_title：Parasitology

authors： D'Andrea PS,Maroja LS,Gentile R,Cerqueira R,Maldonado Júnior A,Rey L

更新日期：2000-06-01 00:00:00

abstract：:RNA extracted from purified parasites of Plasmodium knowlesi was fractionated using agarose gel electrophoresis. Preparations from para sites grown both in vivo and in vitro contained species of RNA with sedimentation coefficients of 4-0S, 5-0S, 16-6S, 24-2S, 31-4S, 38-0S and 48-3S. There was less RNA present in paras...

journal_title：Parasitology

authors： Trigg PI,Shakespeare PG,Burt SJ,Kyd SI

更新日期：1975-10-01 00:00:00

abstract：:Laboratory experiments indicated that the active life-span of the cercariae of Cryptocotyle lingua was temperature-dependent. An increase in water temperature and population age both correlated with a tendency for the organisms to become decaudate. The larvae were strongly photoresponsive to lateral light but with tim...

journal_title：Parasitology

authors： Rea JG,Irwin SW

更新日期：1992-08-01 00:00:00

abstract：:An electron microscopical study was made on the development of Eimeria dispersa in the small intestine of the domestic turkey. Turkey poults, 10-14 days of age, were inoculated with oocysts and pieces of intestinal tissue were fixed at intervals between 3.5 and 114 h after inoculation. Sporozoites were occasionally se...

journal_title：Parasitology

authors： Millard BJ,Lawn AM

更新日期：1982-02-01 00:00:00

abstract：:Isolates of Trypanosoma cruzi from human patients, domestic and sylvatic animals and vector insects were obtained in different areas of Argentina. Electrophoretic patterns of enzymes from extracts of 95 isolates were analysed. On the basis of zymograms providing information on 10 loci, 12 zymodemes are described accor...

journal_title：Parasitology

authors： de Luca D'oro GM,Gardenal CN,Perret B,Crisci JV,Montamat EE

更新日期：1993-11-01 00:00:00

abstract：:Infectious agents have considerable potential to regulate or constrain the population growth of vertebrate hosts in natural habitats. A broad theoretical framework provides many insights into how the biology of the parasite and the demography of the host interact to determine this impact. It may manifest itself as a s...

journal_title：Parasitology

authors： Anderson RM

更新日期：1995-01-01 00:00:00

abstract：:The efficiency of treatment of human infections with the unicellular eukaryotic pathogens such as fungi and protozoa remains deeply unsatisfactory. For example, the mortality rates from nosocomial fungemia in critically ill, immunosuppressed or post-cancer patients often exceed 50%. A set of six systemic clinical azol...

journal_title：Parasitology

authors： Lepesheva GI,Friggeri L,Waterman MR

更新日期：2018-12-01 00:00:00

abstract：:Vesiculated protoscoleces (VP) were produced by culturing freshly collected protoscoleces from Echinococcus granulosus horse liver hydatids in RPMI 1640 monophasic medium at 37 degrees C for 18 days. Half of the VP were used as such, the other half used after killing them by freeze-thawing. Nine-day-old chicken heart ...

journal_title：Parasitology

authors： Janssen D,De Rycke PH,De Ridder L

更新日期：1990-06-01 00:00:00

abstract：:Parasites of the genera Plasmodium and Haemoproteus (Apicomplexa: Haemosporida) are a diverse group of pathogens that infect birds nearly worldwide. Despite their ubiquity, the ecological and evolutionary factors that shape the diversity and distribution of these protozoan parasites among avian communities and geograp...

journal_title：Parasitology

authors： Fecchio A,Svensson-Coelho M,Bell J,Ellis VA,Medeiros MC,Trisos CH,Blake JG,Loiselle BA,Tobias JA,Fanti R,Coffey ED,DE Faria IP,Pinho JB,Felix G,Braga EM,Anciães M,Tkach V,Bates J,Witt C,Weckstein JD,Ricklefs RE,

更新日期：2017-06-01 00:00:00

abstract：:Recent publications demonstrated that a fragment of a Neospora caninum ROP2 family member antigen represents a promising vaccine candidate. We here report on the cloning of the cDNA encoding this protein, N. caninum ROP2 family member 1 (NcROP2Fam-1), its molecular characterization and localization. The protein posses...

journal_title：Parasitology

authors： Alaeddine F,Hemphill A,Debache K,Guionaud C

更新日期：2013-07-01 00:00:00

abstract：:The protein composition of Schistosoma mansoni was analysed by electrophoresis in polyacrylamide slab gel in the presence of sodium dodecyl sulphate. A high degree of identity existed between protein patterns obtain from immature and adult parasites of the two sexes. Some stage-and sex-specific components were indenti...

journal_title：Parasitology

authors： Ruppel A,Cioli D

更新日期：1977-12-01 00:00:00

abstract：:Trials were carried out to study the humoral immune response of blackflies to filariae following infection using the intrathoracic injection technique. An induced 66 kDa protein was abundant in the haemolymph of the European species Simulium ornatum following infection with bovine Onchocerca lienalis. This protein was...

journal_title：Parasitology

authors： Hagen HE,Grunewald J,Ham PJ

更新日期：1994-12-01 00:00:00

abstract：:Ticks have numerous natural enemies, but only a few species have been evaluated as tick biocontrol agents (BCAs). Some laboratory results suggest that several bacteria are pathogenic to ticks, but their mode of action and their potential value as biocontrol agents remain to be determined. The most promising entomopath...

journal_title：Parasitology

authors： Samish M,Ginsberg H,Glazer I

更新日期：2004-01-01 00:00:00

abstract：:Full-length cDNAs encoding cytosolic (SODc) and putative extracellular (SODe) Cu/Zn superoxide dismutases (SODs) from the ovine gastrointestinal parasitic nematode Haemonchus contortus have been isolated and characterized. The predicted sequences of the H. contortus SODs showed strong homology to other helminth SODs, ...

journal_title：Parasitology

authors： Liddell S,Knox DP

更新日期：1998-04-01 00:00:00

abstract：:Diseases caused by viruses are a constant and major problem for livestock production world wide. The diseases range from highly contagious acute forms with high mortality, to chronic disabling diseases with an insidious effect on production. Such diseases cannot be regarded as static in nature due to the highly mutabl...

journal_title：Parasitology

authors： Crowther JR

更新日期：1998-01-01 00:00:00

abstract：:The biodiversity of Trypanosoma cruzi is one of the main factors complicating the understanding of its molecular epidemiology. As an alternative to classical genetic methods, investigators have used DNA-mediated transformation techniques to study this diversity. Recently, transient expression data were shown to correl...

journal_title：Parasitology

authors： Laurent JP,Swindle J

更新日期：1999-12-01 00:00:00

abstract：:The in vitro effects of 4 arylimidamides (DB811, DB786, DB750 and DB766) against the proliferative tachyzoite stage of the apicomplexan parasite Besnoitia besnoiti were investigated. These four compounds had been shown earlier to exhibit in vitro activities in the nanomolar range against the related apicomplexans Neos...

journal_title：Parasitology

authors： Cortes HC,Muller N,Boykin D,Stephens CE,Hemphill A

更新日期：2011-04-01 00:00:00

abstract：:In light of the low success rate of target-based genomics and HTS (High Throughput Screening) approaches in anti-infective drug discovery, in silico structure-based drug design (SBDD) is becoming increasingly prominent at the forefront of drug discovery. In silico SBDD can be used to identify novel enzyme inhibitors r...

journal_title：Parasitology

authors： Cunningham F,McPhillie MJ,Johnson AP,Fishwick CW

更新日期：2014-01-01 00:00:00

abstract：:Three cDNAs encoding rhoptry-associated protein 1 (RAP-1) homologues were found in the Babesia gibsoni EST database. Based on similarities to BgRAP-1a, which was identified previously by serological screening of a cDNA merozoite library, the two new genes were designated BgRAP-1b (33.7%) and BgRAP-1c (57%). Mice antis...

journal_title：Parasitology

authors： Terkawi MA,Amornthep A,Ooka H,Aboge G,Jia H,Goo YK,Nelson B,Yamagishi J,Nishikawa Y,Igarashi I,Kawazu SI,Fujisaki K,Xuan X

更新日期：2009-09-01 00:00:00

abstract：:Highly purified mitochondrial fractions have been isolated from the intraerythrocytic stages of two mammalian Plasmodium spp., Plasmodium yoelii of rodents and Plasmodium falciparum of man. Mitochondria of the former parasite are cristate whereas those of the latter are essentially acristate. Isolated mitochondria fro...

journal_title：Parasitology

authors： Fry M,Beesley JE

更新日期：1991-02-01 00:00:00

abstract：:While purine transport has been widely studied in protozoa, almost nothing is known about their capacity to salvage pyrimidines. Here, we report a Leishmania major transporter with high affinity for uracil (Km=0.32+/-0.07 microM) which we designated LmU1. This transporter displayed a high degree of specificity, as it ...

journal_title：Parasitology

authors： Papageorgiou IG,Yakob L,Al Salabi MI,Diallinas G,Soteriadou KP,De Koning HP

更新日期：2005-03-01 00:00:00

abstract：:The complete sequence of the 18S small subunit (SSU) ribosomal DNA of Hammondia hammondi and Sarcocystis mucosa was obtained and compared to SSU rDNA sequences of Neospora caninum, Toxoplasma gondii, Besnoitia besnoiti, 2 species of Frenkelia, 3 species of Isospora, and 13 species of Sarcocystis. Analyses showed that ...

journal_title：Parasitology

authors： Jenkins MC,Ellis JT,Liddell S,Ryce C,Munday BL,Morrison DA,Dubey JP

更新日期：1999-08-01 00:00:00

abstract：:Australian tea tree oil (TTO) and its extract terpinen-4-ol (T4O) are found to be effective in moderating demodex-related diseases. Their possible effects are lowering the mite counts, relieving the demodex-related symptoms and modulating the immune system especially the inflammatory response. This review summarizes t...

journal_title：Parasitology

authors： Lam NSK,Long XX,Griffin RC,Chen MK,Doery JC

更新日期：2018-10-01 00:00:00