Abstract:
:Australian tea tree oil (TTO) and its extract terpinen-4-ol (T4O) are found to be effective in moderating demodex-related diseases. Their possible effects are lowering the mite counts, relieving the demodex-related symptoms and modulating the immune system especially the inflammatory response. This review summarizes the topical treatments of TTO and T4O in human demodicosis, their possible mechanism of actions, side-effects and potential resistance in treating this condition. Although current treatments other than TTO and T4O are relatively effective in controlling the demodex mite population and the related symptoms, more research on the efficacy and drug delivery technology is needed in order to assess its potential as an alternative treatment with minimal side-effect profile, low toxicity and low risk of demodex resistance.
journal_name
Parasitologyjournal_title
Parasitologyauthors
Lam NSK,Long XX,Griffin RC,Chen MK,Doery JCdoi
10.1017/S0031182018000495subject
Has Abstractpub_date
2018-10-01 00:00:00pages
1510-1520issue
12eissn
0031-1820issn
1469-8161pii
S0031182018000495journal_volume
145pub_type
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