Abstract:
:This study was conducted to quantify the association between meteorological variables and incidence of Plasmodium falciparum in areas with unstable malaria transmission in Ethiopia. We used morbidity data pertaining to microscopically confirmed cases reported from 35 sites throughout Ethiopia over a period of approximately 6-7 years. A model was developed reflecting biological relationships between meteorological and morbidity variables. A model that included rainfall 2 and 3 months earlier, mean minimum temperature of the previous month and P. falciparum case incidence during the previous month was fitted to morbidity data from the various areas. The model produced similar percentages of over-estimation (19.7% of predictions exceeded twice the observed values) and under-estimation (18.6%, were less than half the observed values). Inclusion of maximum temperature did not improve the model. The model performed better in areas with relatively high or low incidence (>85% of the total variance explained) than those with moderate incidence (55-85% of the total variance explained). The study indicated that a dynamic immunity mechanism is needed in a prediction model. The potential usefulness and drawbacks of the modelling approach in studying the weather-malaria relationship are discussed, including a need for mechanisms that can adequately handle temporal variations in immunity to malaria.
journal_name
Parasitologyjournal_title
Parasitologyauthors
Abeku TA,De Vlas SJ,Borsboom GJ,Tadege A,Gebreyesus Y,Gebreyohannes H,Alamirew D,Seifu A,Nagelkerke NJ,Habbema JDdoi
10.1017/s0031182004005013subject
Has Abstractpub_date
2004-06-01 00:00:00pages
585-93issue
Pt 6eissn
0031-1820issn
1469-8161journal_volume
128pub_type
杂志文章相关文献
PARASITOLOGY文献大全abstract::There has been an enormous growth in the development of biotechnological applications, where advances in the techniques of microelectronic fabrication and the technologies of miniaturization and integration in semiconductor industries are being applied to the production of Laboratory-on-a-Chip devices. The aim of this...
journal_title:Parasitology
pub_type: 杂志文章,评审
doi:10.1017/s0031182099004126
更新日期:1998-01-01 00:00:00
abstract::Renal infections by parasitic ciliates were studied in adult snails of Helix aspersa aspersa and Helix aspersa maxima collected from 2 mixed rearing system-based heliciculture farms located in Galicia (NW Spain). The occurrence of ciliates was also examined in slugs (Deroceras reticulatum) invading the greenhouses whe...
journal_title:Parasitology
pub_type: 杂志文章
doi:10.1017/S0031182009006040
更新日期:2009-06-01 00:00:00
abstract::Flow cytometric analysis of the binucleated protozoan parasite Giardia intestinalis gave DNA histograms with a broad G1 peak and a definable G2 + M peak with twice the DNA content of G1. Twenty-four hour treatment with metronidazole arrested cell cycle progression of susceptible trophozoites in the G2 + M phase, but h...
journal_title:Parasitology
pub_type: 杂志文章
doi:10.1017/s0031182000059047
更新日期:1989-12-01 00:00:00
abstract::The glycogen stores of adult Schistosoma mansoni worms could be labelled by incubation of the worms, after an initial reduction of their glycogen content, in the presence of [6-14C]glucose. Subsequent breakdown of the labelled glycogen by the parasite revealed that glycogen was degraded to lactate and carbon dioxide. ...
journal_title:Parasitology
pub_type: 杂志文章
doi:10.1017/s0031182000059692
更新日期:1989-02-01 00:00:00
abstract::Antibodies against variable antigens expressed on the surface of Plasmodium falciparum-infected erythrocytes are believed to be important for protection against malaria. A target for these antibodies is the P. falciparum erythrocyte membrane protein 1, PfEMP1, which is encoded by around 50 var genes and undergoes clon...
journal_title:Parasitology
pub_type: 杂志文章
doi:10.1017/s0031182099004485
更新日期:1999-07-01 00:00:00
abstract::The amitochondriate parasitic protist Trichomonas vaginalis can utilize either glucose or maltose as carbon and energy source. The mechanisms of maltose utilization were explored with uptake experiments using radio-isotope labelled maltose in combination with the silicone-oil centrifugation technique and enzymatic ass...
journal_title:Parasitology
pub_type: 杂志文章
doi:10.1017/s0031182000081026
更新日期:1995-01-01 00:00:00
abstract::Why do parasites kill their hosts? During this past decade, research in three different areas; evolutionary ecology, medical microbiology, and population genetics has provided theory and data that address this and related questions of selection and the evolution and maintenance of parasite virulence. A general theory ...
journal_title:Parasitology
pub_type: 杂志文章,评审
doi:10.1017/s0031182000073054
更新日期:1990-01-01 00:00:00
abstract::It is suspected that host-parasite interactions are influenced by climatic oscillations such as the North Atlantic Oscillation (NAO). However, the effects of climatic oscillations on host-parasite interactions have never been investigated. A long-term (1982-1999) dataset of the host snail Lymnaea stagnalis and tremato...
journal_title:Parasitology
pub_type: 杂志文章
doi:10.1017/S0031182011000655
更新日期:2011-07-01 00:00:00
abstract::Australian tea tree oil (TTO) and its extract terpinen-4-ol (T4O) are found to be effective in moderating demodex-related diseases. Their possible effects are lowering the mite counts, relieving the demodex-related symptoms and modulating the immune system especially the inflammatory response. This review summarizes t...
journal_title:Parasitology
pub_type: 杂志文章,评审
doi:10.1017/S0031182018000495
更新日期:2018-10-01 00:00:00
abstract::African sleeping sickness is a parasitic disease transmitted through the bites of tsetse flies of the genus Glossina. We constructed mechanistic models for the basic reproduction number, R0, of Trypanosoma brucei gambiense and Trypanosoma brucei rhodesiense, respectively the causative agents of West and East African h...
journal_title:Parasitology
pub_type: 杂志文章
doi:10.1017/S0031182010001496
更新日期:2011-04-01 00:00:00
abstract::Traditionally, the family Campulidae has been associated either with the family Fasciolidae, parasites of ruminants, or the Acanthocolpidae, parasites of fishes, based on morphological similarities. Since morphology does not seem to resolve clearly the problem of the relationships of campulids, we have used the sequen...
journal_title:Parasitology
pub_type: 杂志文章
doi:10.1017/s0031182098003126
更新日期:1998-10-01 00:00:00
abstract::In parallel with massive research efforts in human schistosomiasis over the past 30 years, persistent efforts have been made to understand the basis for compatibility and incompatibility in molluscan schistosomiasis. Snail plasma contains molecules that are toxic to trematodes, but these seem to kill only species that...
journal_title:Parasitology
pub_type: 杂志文章,评审
doi:10.1017/s0031182001008137
更新日期:2001-01-01 00:00:00
abstract::Alveolar echinococcosis (AE) is a zoonotic parasitic diseases caused by a cestode parasite known as Echinococcus multilocularis. The parasite has a wildlife cycle with definitive hosts (foxes) and small mammals as intermediate hosts (rodents) while humans are the accidental hosts. Parasite infection pressure relation ...
journal_title:Parasitology
pub_type: 杂志文章
doi:10.1017/S0031182019001720
更新日期:2020-03-01 00:00:00
abstract::A cDNA clone codifying ribosomal protein L25 was isolated from a Leishmania braziliensis cDNA gene library. The alignment of the amino acid sequence deduced from this gene with other proteins revealed that this protein is related to the L23/25 rihosomal protein family. This is so because this protein shows, in its C-t...
journal_title:Parasitology
pub_type: 杂志文章
doi:10.1017/s0031182002001804
更新日期:2002-07-01 00:00:00
abstract::Quinine (QN) and quinidine (QND) have been commonly used as effective and affordable antimalarials for over many years. Quinine primarily is used for severe malaria treatment. However, plasmodia resistance to these drugs and poor patient compliance limits their administration to the patients. The declining sensitivity...
journal_title:Parasitology
pub_type: 杂志文章
doi:10.1017/S003118201200176X
更新日期:2013-03-01 00:00:00
abstract::SUMMARY Leishmania are protozoan parasites spread by a sandfly insect vector and causing a spectrum of diseases collectively known as leishmaniasis. The disease is a significant health problem in many parts of the world, resulting in an estimated 1·3 million new cases and 30 000 deaths annually. Current treatment is b...
journal_title:Parasitology
pub_type: 杂志文章
doi:10.1017/S003118201400095X
更新日期:2014-07-30 00:00:00
abstract::Schistosomula of Schistosoma mansoni were incubated in RPMI 1640 medium containing 10% fetal calf serum, 10% human portal venous or 10% human peripheral venous sera in the presence of bromodeoxyuridine (BrdU) in order to measure differences in cell proliferation. The rates of cell proliferation as expressed by BrdU la...
journal_title:Parasitology
pub_type: 杂志文章
doi:10.1017/s0031182098003096
更新日期:1998-10-01 00:00:00
abstract::Monensin (Mon) is an anticoccidial polyether ionophore widely used to control coccidiosis. The extensive use of polyether ionophores on poultry farms resulted in widespread resistance, but the underlying resistance mechanisms are unknown in detail. For analysing the mode of action by which resistance against polyether...
journal_title:Parasitology
pub_type: 杂志文章
doi:10.1017/S0031182017001512
更新日期:2018-03-01 00:00:00
abstract::Blood examination by microhaematocrit and haemoculture of 459 snakes belonging to 37 species revealed 2.4% trypanosome prevalence in species of Viperidae (Crotalus durissus and Bothrops jararaca) and Colubridae (Pseudoboa nigra). Trypanosome cultures from C. durissus and P. nigra were behaviourally and morphologically...
journal_title:Parasitology
pub_type: 杂志文章
doi:10.1017/S0031182008004253
更新日期:2008-04-01 00:00:00
abstract::The protein composition of Schistosoma mansoni was analysed by electrophoresis in polyacrylamide slab gel in the presence of sodium dodecyl sulphate. A high degree of identity existed between protein patterns obtain from immature and adult parasites of the two sexes. Some stage-and sex-specific components were indenti...
journal_title:Parasitology
pub_type: 杂志文章
doi:10.1017/s003118200005188x
更新日期:1977-12-01 00:00:00
abstract::BALB/c mice were characterized as more resistant to infection with Heligmosomoides polygyrus (Nematoda) than C57BL/6 mice based on lower establishment and survival during a primary infection and stronger protection induced by an immunizing regime. It was hypothesized, therefore, that C57BL/6 mice would be more heavily...
journal_title:Parasitology
pub_type: 杂志文章
doi:10.1017/s0031182000059953
更新日期:1991-12-01 00:00:00
abstract::The Baltic Sea is characterized by organisms that can tolerate brackish water. Because of the Sea's history during glacial times, its flora and fauna (and also their parasites) can be traced to marine, freshwater and genuine brackish elements beside glacial relics. Snails, planktonic copepods, benthic amphipods and is...
journal_title:Parasitology
pub_type: 杂志文章,评审
doi:10.1017/s0031182002001567
更新日期:2002-01-01 00:00:00
abstract::The pentastomid parasite, Raillietiella frenata, is native to Asia where it infects the Asian House gecko, Hemidactylus frenatus. This gecko has been widely introduced and recently R. frenata was found in introduced populations of cane toads (Rhinella marina) in Australia, indicating a host-switch from introduced geck...
journal_title:Parasitology
pub_type: 杂志文章
doi:10.1017/S0031182014001759
更新日期:2015-04-01 00:00:00
abstract::Past and more recent research has examined the ultrastructure, metabolism, cell biology, genomics and post-genomics of schistosome schistosomula. These areas are considered and discussed in this review with particular emphasis on (1) the early migration phases through the host, (2) interaction of the host immune respo...
journal_title:Parasitology
pub_type: 杂志文章,评审
doi:10.1017/S0031182006001648
更新日期:2007-04-01 00:00:00
abstract::Laboratory experiments indicated that the active life-span of the cercariae of Cryptocotyle lingua was temperature-dependent. An increase in water temperature and population age both correlated with a tendency for the organisms to become decaudate. The larvae were strongly photoresponsive to lateral light but with tim...
journal_title:Parasitology
pub_type: 杂志文章
doi:10.1017/s0031182000073789
更新日期:1992-08-01 00:00:00
abstract::Schistosoma mansoni eggs, miracidia and primary sporocysts were labelled with phalloidin-rhodamine to visualize filamentous actin structures. Analysis of these forms by confocal fluorescence microscopy revealed the presence of previously well-defined circular and longitudinal muscle layers. Besides these muscular laye...
journal_title:Parasitology
pub_type: 杂志文章
doi:10.1017/S0031182006000400
更新日期:2006-09-01 00:00:00
abstract::Syphacia stroma (von Linstow, 1884) Morgan, 1932 and Syphacia frederici Roman, 1945 are oxyurid nematodes that parasitize two murid rodents, Apodemus sylvaticus and Apodemus flavicollis, on the European mainland. Only S. stroma has been recorded previously in Apodemus spp. from the British Isles. Despite the paucity o...
journal_title:Parasitology
pub_type: 杂志文章
doi:10.1017/S0031182017001470
更新日期:2018-03-01 00:00:00
abstract::We estimate the incidence rate, serological conversion rate and basic case reproduction number (R0) of Leishmania infantum from a cohort study of 126 domestic dogs exposed to natural infection rates over 2 years on Marajó Island, Pará State, Brazil. The analysis includes new methods for (1) determining the number of s...
journal_title:Parasitology
pub_type: 杂志文章
doi:10.1017/s0031182097001200
更新日期:1997-08-01 00:00:00
abstract::Parasites often induce behavioural changes in their host. However, it is not necessarily easy to determine whether these changes are representative of an adaptation of the parasite (parasite manipulation), an adaptive response of the host or a side-effect of infection. In a solitary parasitoid of Drosophila larvae (Le...
journal_title:Parasitology
pub_type: 杂志文章
doi:10.1017/S0031182006009930
更新日期:2006-06-01 00:00:00
abstract::A distinct 8 kDa calcium-binding protein (CaBP) is preferentially expressed at the cercarial stage during the life-cycle of the schistosome. Available data indicate that this CaBP may be associated with tissue/organ remodelling (involving protein degradation and synthesis of new proteins) during transformation of the ...
journal_title:Parasitology
pub_type: 杂志文章
doi:10.1017/s0031182003003858
更新日期:2003-10-01 00:00:00