Resistance towards monensin is proposed to be acquired in a Toxoplasma gondii model by reduced invasion and egress activities, in addition to increased intracellular replication.

abstract：:Cytoadherence of Plasmodium falciparum-infected erythrocytes to melanoma cells was analysed using strains or isolates of parasites expressing or not expressing knobs (K+ or K- phenotype) on the erythrocyte surface. Both K+ and K- parasites had the capacity to cytoadhere to melanoma cells. Using a panel of melanoma cel...

journal_title：Parasitology

authors： Ruangjirachuporn W,Afzelius BA,Paulie S,Wahlgren M,Berzins K,Perlmann P

更新日期：1991-06-01 00:00:00

abstract：:To compare the structures of natural and re-established populations of Ascaris in humans, universal (mass) chemotherapy was carried out at the beginning and the end of the study year using pyrantel pamoate. Worms expelled within 48 h of treatment were collected, their sex determined, and measurements made of length, w...

journal_title：Parasitology

authors： Peng W,Cui X,Zhou X

更新日期：2002-06-01 00:00:00

abstract：:Strongyloidiasis is frequently asymptomatic and diagnosis of latent infection is difficult due to limitations of current parasitological and serological methods. This study aimed to verify the use of conventional polymerase chain reaction (PCR) assay for molecular diagnosis of Strongyloides stercoralis infection. Fres...

journal_title：Parasitology

authors： Sitta RB,Malta FM,Pinho JR,Chieffi PP,Gryschek RC,Paula FM

更新日期：2014-04-01 00:00:00

abstract：:Giardia lamblia localize and multiply in the small intestine and may cause acute or chronic diarrhoea with malabsorption of fat, protein and other nutrients. Abnormal pancreatic function has been documented in giardiasis and trophozoites directly inhibit pancreatic lipase activity in vitro. The aim of this study was t...

journal_title：Parasitology

authors： Seow F,Katelaris P,Ngu M

更新日期：1993-04-01 00:00:00

abstract：:Insecticide-treated nets (ITNs) are a major tool to control malaria. Over recent years increased ITN coverage has been associated with decreased malaria transmission. However, ITN 'misuse' has been increasingly reported and whether this emergent behaviour poses a threat to successful malaria control and elimination is...

journal_title：Parasitology

authors： Honjo K,Chaves LF,Satake A,Kaneko A,Minakawa N

更新日期：2013-04-01 00:00:00

abstract：:Theileria-free waterbuck (Kobus defassa) born in captivity were successfully infected with Theileria parva sporozoites derived from ticks infected by feeding on African buffalo (Syncerus caffer). All waterbuck underwent mild infections with the development of sporadic schizont and piroplasm parasitosis when inoculated...

journal_title：Parasitology

authors： Stagg DA,Bishop RP,Morzaria SP,Shaw MK,Wesonga D,Orinda GO,Grootenhuis JG,Molyneux DH,Young AS

更新日期：1994-06-01 00:00:00

abstract：:Infection of breeding hens with Eimeria maxima induces production of Eimeria-specific IgG antibodies which are transferred to hatchlings via the egg yolk and confer a high degree of maternal immunity against homologous challenge and partial immunity to infection with another important species, Eimeria tenella. As an e...

journal_title：Parasitology

authors： Smith NC,Wallach M,Petracca M,Braun R,Eckert J

更新日期：1994-12-01 00:00:00

abstract：:The ribosomal RNA (rRNA) gene units of Schistosoma mansoni and S. rodhaini, of the lateral spined egg group, have been studied. The schistosome rRNA gene unit consists of a regular interspersion of the two genes encoding the large and small rRNA units with two spacers. The large spacer is not transcribed while the sma...

journal_title：Parasitology

authors： Walker TK,Simpson AJ,Rollinson D

更新日期：1989-02-01 00:00:00

abstract：:Genome sequencing has greatly contributed to our understanding of parasitic protozoa. This is particularly the case for Cryptosporidium species (phylum Apicomplexa) which are difficult to propagate. Because of their polymorphic nature, simple sequence repeats have been used extensively as genotypic markers to differen...

journal_title：Parasitology

authors： Widmer G

更新日期：2018-08-01 00:00:00

abstract：:A procedure is described for the isolation of sub-cellular fractions from bloodstream forms of Trypanosoma brucei. The method leaves intact most of the nuclei, mitochondria and microbodies. All the fractions have been chemically characterized and tested for 10 enzymatic markers. About 5% of total cell protein was isol...

journal_title：Parasitology

authors： Rovis L,Baekkeskov S

更新日期：1980-06-01 00:00:00

abstract：:Transmission experiments were conducted to compare the transmissibility of genetically different Trypanosoma congolense (Savannah subgroup) strains isolated from cattle in a trypanosomiasis endemic area of eastern Zambia. A total of 17 strains were compared. Three strains were extremely virulent with a short pre-paten...

journal_title：Parasitology

authors： Masumu J,Marcotty T,Ndeledje N,Kubi C,Geerts S,Vercruysse J,Dorny P,van den Bossche P

更新日期：2006-09-01 00:00:00

abstract：:The current trend of antimony (Sb) unresponsiveness in the Indian subcontinent is a major impediment to effective chemotherapy of visceral leishmaniasis (VL). Although contributory mechanisms studied in laboratory-raised Sb-R parasites include an up-regulation of drug efflux pumps and increased thiols, their role in c...

journal_title：Parasitology

authors： Mandal G,Wyllie S,Singh N,Sundar S,Fairlamb AH,Chatterjee M

更新日期：2007-11-01 00:00:00

abstract：:In previous studies, ultrastructural observations revealed a large number of gap junctions (GJs) in the neck and immature proglottid tissues of Taenia solium tapeworms. In these helminths, cytoplasmic glycogen sacs are connected by numerous discrete GJs to other cells throughout the maturing strobilar tissue. Disconti...

journal_title：Parasitology

authors： Zurabian R,Landa A,Robert L,Willms K

更新日期：2008-08-01 00:00:00

abstract：:Cryptosporidium parvum is a zoonotic protozoan parasite that mainly affects the ileum of humans and livestock, with the potential to cause severe enteric disease. We describe the complete life cycle of C. parvum in an in vitro system. Infected cultures of the human ileocecal epithelial cell line (HCT-8) were observed ...

journal_title：Parasitology

authors： Borowski H,Thompson RC,Armstrong T,Clode PL

更新日期：2010-01-01 00:00:00

abstract：:The epicontinental fauna of the Iberian Peninsula is strongly influenced by its geographical history. As the possibilities for dispersion of organisms into and from this region were (and still are) limited, the local fauna consists almost exclusively of endemic species. Almost all Iberian freshwater fishes of the fami...

journal_title：Parasitology

authors： Benovics M,Desdevises Y,Šanda R,Vukić J,Scheifler M,Doadrio I,Sousa-Santos C,Šimková A

更新日期：2020-04-01 00:00:00

abstract：:Differentiation of epimastigotes and production of infective metacyclic forms of Trypanosoma congolense were examined in a culture system which enabled manipulation of the population density of insect forms. Scanning electron microscopy of cultures revealed the attachment sites of epimastigotes in detail, showing them...

journal_title：Parasitology

authors： Prain CJ,Ross CA

更新日期：1990-02-01 00:00:00

abstract：:Susceptibility to oxidative stress is a well-established feature of the malarial parasite. Pharmacologists have taken advantage of this property to design highly effective pro-oxidant antimalarial drugs. Less well appreciated is the fact that nutritional manipulation of host oxidative stress status by dietary means ca...

journal_title：Parasitology

authors： Levander OA,Ager AL Jr

更新日期：1993-01-01 00:00:00

abstract：:The snail Bulinus nasutus 1214 possesses a potent haemagglutinin (end-point titre with human erythrocytes, 2(-18)) in its cell-free haemolymph which also binds to the miracidia (but not other larvae) of the incompatible parasite Schistosoma margrebowiei. We have purified a protein possessing this haemagglutinating pro...

journal_title：Parasitology

authors： Harris RA,Preston TM,Southgate VR

更新日期：1993-02-01 00:00:00

abstract：:New treatment strategies for schistosomiasis should be evaluated, since resistant strains to the only available drug, Praziquantel, have already been described. Thus, we demonstrated antiparasitic effects of ethanolic extracts of Jatropha gossypiifolia and Piper arboreum on cercariae and adult worms of Schistosoma man...

journal_title：Parasitology

authors： da Silva Alves RR,Mendes Rodrigues JG,Teles-Reis A,Araújo Nogueira R,Correia Lima Licá I,Sampaio Lira MG,da Silva Alves R,Silva-Souza N,Aguiar Dos Santos Andrade TJ,Silva Miranda G

更新日期：2020-12-01 00:00:00

abstract：:Oesophagostomum dentatum stages were investigated for glutathione S-transferase (GST) expression at the protein and mRNA levels. GST activity was detected in all stages (infectious and parasitic stages including third- and fourth-stage larvae of different ages as well as males and females) and could be dose-dependentl...

journal_title：Parasitology

authors： Joachim A,Ruttkowski B

更新日期：2008-09-01 00:00:00

abstract：:Antigenic differences between intra-lymphocytic theilerial parasites isolated from the blood of 18 African buffalo and grown in vitro were assessed with anti-schizont monoclonal antibodies (mAbs). There was marked antigenic diversity both between isolates from different buffalo and between isolates taken at different ...

journal_title：Parasitology

authors： Conrad PA,Stagg DA,Grootenhuis JG,Irvin AD,Newson J,Njamunggeh RE,Rossiter PB,Young AS

更新日期：1987-06-01 00:00:00

abstract：:Since 2004 there has been a remarkable increment in our knowledge of the proteins and glycans that reside at, or are released from the surfaces of schistosomes in the mammalian host. Initial characterization of the soluble proteome permits distinctions to be made between the parasite secretome and its necrotome. The p...

journal_title：Parasitology

authors： Wilson RA

更新日期：2012-08-01 00:00:00

abstract：:A comparison has been made of the interactions between passively transferred and actively acquired immunity in regulating populations of Taenia hydatigena and T. ovis. When ewes were grazed prior to parturition under a high infection pressure, immunity was transferred to their offspring for up to 8 weeks. A qualitativ...

journal_title：Parasitology

authors： Gemmell MA,Lawson JR,Roberts MG,Griffin JF

更新日期：1990-08-01 00:00:00

abstract：:The development and growth of Haemonchus contortus was studied in the stomach of the laboratory rabbit. Less than 1% of the ensheathed infective larvae given to rabbits became established, whereas after exsheathment in vitro under physiological conditions, 20-30% of the larvae administered developed to the 4th stage. ...

journal_title：Parasitology

authors： Mapes CJ,Gallie GJ

更新日期：1977-06-01 00:00:00

abstract：:Ivermectin treatment may induce severe adverse reactions in some individuals heavily infected with Loa loa. This hampers the implementation of mass ivermectin treatment against onchocerciasis in areas where Onchocerca volvulus and L. loa are co-endemic. In order to identify factors, including co-infections, which may ...

journal_title：Parasitology

authors： Pion SD,Clarke P,Filipe JA,Kamgno J,Gardon J,Basáñez MG,Boussinesq M

更新日期：2006-06-01 00:00:00

abstract：:Within the genus Cryptosporidium 2 lineages have evolved, one adapted to the acid environment of the stomach and abomasum, the other comprising parasites that multiply in the small intestine. We tested whether the release of sporozoites from oocysts, a process known as excystation, is triggered by conditions which mim...

journal_title：Parasitology

authors： Widmer G,Klein P,Bonilla R

更新日期：2007-10-01 00:00:00

abstract：:The host recognition and invasion process of Myxobolus cerebralis actinospores (triactinomyxon, TAM) was studied on a genetic level. A small-scale in vitro assay was developed to activate a large number of TAMs simultaneously, and to monitor the host invasion in the absence of live fish. The transcriptomes of non-acti...

journal_title：Parasitology

authors： Eszterbauer E,Kallert DM,Grabner D,El-Matbouli M

更新日期：2009-04-01 00:00:00

abstract：:We have recently identified 2 surface proteins in Entamoeba histolytica as intermediate subunits of galactose- and N-acetyl-D-galactosamine-inhibitable lectin (EhIgl1 and EhIgl2); these proteins both contain multiple CXXC motifs. Here, we report the molecular characterization of the corresponding proteins in Entamoeba...

journal_title：Parasitology

authors： Tachibana H,Cheng XJ,Kobayashi S,Okada Y,Itoh J,Takeuchi T

更新日期：2007-12-01 00:00:00

abstract：:Early in the history of schistosomiasis research, children under 5 years of age were known to be infected. Although this problem was recognized over 100 years ago, insufficient action has been taken to address this issue. Under current policy, such infected children only receive their first antiparasitic treatment (pr...

journal_title：Parasitology

authors： Bustinduy AL,Wright S,Joekes EC,Kabatereine NB,Reinhard-Rupp J,King CH,Stothard JR

更新日期：2017-10-01 00:00:00

abstract：:Leishmania are obligatory intracellular parasitic protozoa that cycle between sand fly mid-gut and phagolysosomes of mammalian macrophages. They have developed genetically programmed changes in gene and protein expression that enable rapid optimization of cell function according to vector and host environments. During...

journal_title：Parasitology

authors： Tsigankov P,Gherardini PF,Helmer-Citterich M,Zilberstein D

更新日期：2012-08-01 00:00:00