Current status of vaccination against African trypanosomiasis.

abstract：:Leishmania are obligatory intracellular parasitic protozoa that cycle between sand fly mid-gut and phagolysosomes of mammalian macrophages. They have developed genetically programmed changes in gene and protein expression that enable rapid optimization of cell function according to vector and host environments. During...

journal_title：Parasitology

authors： Tsigankov P,Gherardini PF,Helmer-Citterich M,Zilberstein D

更新日期：2012-08-01 00:00:00

abstract：:The worldwide economic impact of Neospora caninum infection has caused the development of effective vaccines to become one of the main goals in the field of neosporosis research. In this study, the protection conferred by antigens from inactivated whole tachyzoites (TZ) and a tachyzoite-bradyzoite mixture (TZ-BZ) of N...

journal_title：Parasitology

authors： Rojo-Montejo S,Collantes-Fernández E,Rodríguez-Marcos S,Pérez-Zaballos F,López-Pérez I,Prenafeta A,Ortega-Mora LM

更新日期：2011-09-01 00:00:00

abstract：:The rapid elimination of the intestinal phase of Trichinella spiralis in NIH mice is associated with progressive inflammation of the intestinal tract. The non-specific effects of this inflammation were studied in mice concurrently infected with an unrelated parasite, Hymenolepis diminuta, which does not stimulate a vi...

journal_title：Parasitology

authors： Behnke JM,Bland PW,Wakelin D

更新日期：1977-08-01 00:00:00

abstract：:Little is known about the effects of infection with Borrelia burgdorferi, the bacterium that causes Lyme disease, on its tick vectors. The purpose of this study was to determine the behavioural and ecological effects of infection by the bacterium in nymphal and adult black-legged (Ixodes scapularis) ticks. We found th...

journal_title：Parasitology

authors： Lefcort H,Durden LA

更新日期：1996-08-01 00:00:00

abstract：:Pasteuria penetrans is a Gram-positive endospore-producing bacterium that is a parasite of root-knot nematodes. Attachment of endospores to the cuticle of the nematode is the first stage in the infection process. Western blot analysis with monoclonal and polyclonal antibodies that recognize the 30 kDa heparin-binding ...

journal_title：Parasitology

authors： Mohan S,Fould S,Davies KG

更新日期：2001-09-01 00:00:00

abstract：:An ultrastructural study has been performed on radiation-attenuated parasites fixed in situ during their extended stay in the lungs. At day 7 post-infection all parasites were located within blood vessels. In contrast to normally migrating parasites, at days 13 and 21 post-infection the majority of radiation-attenuate...

journal_title：Parasitology

authors： Mastin A,Bickle QD,Wilson RA

更新日期：1985-08-01 00:00:00

abstract：:The World Health Organization announced in November 2014 at the fourth international meeting on 'the control of neglected zoonotic diseases - from advocacy to action', that intervention tools for eliminating Taenia solium taeniosis/cysticercosis (TSTC) are in place. The aim of this work was to elucidate theoretical ou...

journal_title：Parasitology

authors： Johansen MV,Trevisan C,Gabriël S,Magnussen P,Braae UC

更新日期：2017-01-01 00:00:00

abstract：:The relationships between populations of the Deer Mouse (Peromyscus maniculatus) and the White-footed Mouse (P. leucopus) and their respective Cuterebra parasites were examined. Population genetic structure of hosts and parasites was inferred using cytochrome oxidase mitochondrial sequences of specimens from 7 populat...

journal_title：Parasitology

authors： Noel S,Angers B,Lapointe FJ

更新日期：2005-08-01 00:00:00

abstract：:Most of our knowledge about the process of penetration of skin, by cercariae of Schistosoma mansoni, has been gained from studies carried out in vivo with laboratory animals. Human skin is significantly different from that of other animals but there are obvious practical difficulties in directly studying attachment an...

journal_title：Parasitology

authors： Khammo N,Bartlett A,Clothier RH,Whitfield PJ

更新日期：2002-01-01 00:00:00

abstract：:Angiostrongylus cantonensis is a metastrongyloid nematode found widely in the Asia-Pacific region, and the aetiological agent of angiostrongyliasis; a disease characterized by eosinophilic meningitis. Rattus rats are definitive hosts of A. cantonensis, while intermediate hosts include terrestrial and aquatic molluscs....

journal_title：Parasitology

authors： Barratt J,Chan D,Sandaradura I,Malik R,Spielman D,Lee R,Marriott D,Harkness J,Ellis J,Stark D

更新日期：2016-08-01 00:00:00

abstract：:The transmission from one host to another constitutes a challenging obstacle for parasites and is a key determinant of their fitness. Due to their complex life histories involving several different hosts, the free-living dispersal stages (cercariae) of digenean trematodes show a huge diversity in morphology and behavi...

journal_title：Parasitology

authors： Selbach C,Poulin R

更新日期：2018-09-01 00:00:00

abstract：:A novel tetrahydroquinolinyl ester, quinfamide, administered orally in multiple doses for 3 days had an ED50 of 0.25 mg/kg/day (total dose 0.75 mg/kg) for eradicating Entamoeba criceti in hamsters in several tests. It was significantly more active by direct comparison than 3 commercially available amoebicides and at l...

journal_title：Parasitology

authors： Slighter RG,Yarinsky A,Drobeck HP,Bailey DM

更新日期：1980-08-01 00:00:00

abstract：:The respiratory chain of the procyclic stage of Trypanosoma brucei contains the standard complexes I through IV, as well as several alternative enzymes contributing to electron flow. In this work, we studied the function of an alternative NADH : ubiquinone oxidoreductase (NDH2). Depletion of target mRNA was achieved u...

journal_title：Parasitology

authors： Verner Z,Skodová I,Poláková S,Durišová-Benkovičová V,Horváth A,Lukeš J

更新日期：2013-03-01 00:00:00

abstract：:The snail Bulinus nasutus 1214 possesses a potent haemagglutinin (end-point titre with human erythrocytes, 2(-18)) in its cell-free haemolymph which also binds to the miracidia (but not other larvae) of the incompatible parasite Schistosoma margrebowiei. We have purified a protein possessing this haemagglutinating pro...

journal_title：Parasitology

authors： Harris RA,Preston TM,Southgate VR

更新日期：1993-02-01 00:00:00

abstract：:Vertically transmitted parasites (VTPs) such as Wolbachia are expected not only to minimize the damage they inflict on their hosts, but also to protect their hosts against the damaging effects of coinfecting parasites. By modifying the fitness costs of the infection, VTPs can therefore play an important role in the ev...

journal_title：Parasitology

authors： Zélé F,Denoyelle J,Duron O,Rivero A

更新日期：2018-05-01 00:00:00

abstract：:Exponential decay in community similarity as a function of distance is a ubiquitous phenomenon in biogeography. Thus, for parasite communities, pairwise similarity decreases with increasing geographical distance between host populations. This biogeographical rule should also apply along other dimensions characterizing...

journal_title：Parasitology

authors： Poulin R

更新日期：2010-04-01 00:00:00

abstract：:Stratospheric ozone depletion threatens to increase exposure to ultraviolet (UV) radiation which is known to be a factor in a number of diseases. There is little doubt that cumulative exposure to UV radiation is important in the aetiology of non-melanoma skin cancers. Evidence is also strong for a link with cutaneous ...

journal_title：Parasitology

authors： Bentham G

更新日期：1993-01-01 00:00:00

abstract：:The complete nucleotide sequence of the mitochondrial genome was determined for the fish tapeworm Diphyllobothrium latum. This genome is 13,608 bp in length and encodes 12 protein-coding genes (but lacks the atp8), 22 transfer RNA (tRNA) and 2 ribosomal RNA (rRNA) genes, corresponding to the gene complement found thus...

journal_title：Parasitology

authors： Park JK,Kim KH,Kang S,Jeon HK,Kim JH,Littlewood DT,Eom KS

更新日期：2007-05-01 00:00:00

abstract：:An endemic transmission cycle of Babesia microti was discovered in Colorado in the foothills of the Rocky Mountains. B. microti were found by PCR in 4 of 25 Ixodes spinipalpis tick pools tested (a 3.2 % minimum infection rate) and in 87% (13 of 15) of Microtus ochrogaster (the prairie vole) spleen and blood samples. U...

journal_title：Parasitology

authors： Burkot TR,Schneider BS,Pieniazek NJ,Happ CM,Rutherford JS,Slemenda SB,Hoffmeister E,Maupin GO,Zeidner NS

更新日期：2000-12-01 00:00:00

abstract：OBJECTIVE:Unravelling the determinants of parasite life-history traits in natural settings is complex. Here, we deciphered the relationships between biotic, abiotic factors and the variation in 4 life-history traits (body size, egg presence, egg number and egg size) in the fish ectoparasite Tracheliastes polycolpus. We...

journal_title：Parasitology

authors： Loot G,Poulet N,Brosse S,Tudesque L,Thomas F,Blanchet S

更新日期：2011-06-01 00:00:00

abstract：:Blastocystis spp. is the most frequent infectious unicellular, luminal parasite in all species of animals and humans. It has been linked to diarrhoea and irritable bowel syndrome. Saccharomyces boulardii (Sb) is a widely used probiotic that previously showed efficacy against several intestinal pathogens. The aim of th...

journal_title：Parasitology

authors： Méabed EMH,Abdelhafez DN,Abdelaliem YF

更新日期：2019-10-01 00:00:00

abstract：:A multi-subunit antigen (native M(r) > 200 kDa, reduced M(r) 97-100 kDa) has been identified in homogenates of Trichinella spiralis larvae using affinity-purified rabbit anti-keyhole limpet haemocyanin (KLH) antibodies and its cross-reactivity with KLH was confirmed by competition blotting. The antigen was not present...

journal_title：Parasitology

authors： Modha J,Robertson WM,Kennedy MW,Kusel JR

更新日期：1994-11-01 00:00:00

abstract：:A cDNA encoding a beta-galactoside-binding lectin (galectin) was identified by immunoscreening a Haemonchus contortus cDNA library with antisera from lambs vaccinated with a membrane protein complex (H-gal-GP) derived from the parasites' gut. The cDNA sequence, exhibiting a tandem repeat structure and designated Hco-g...

journal_title：Parasitology

authors： Newlands GF,Skuce PJ,Knox DP,Smith SK,Smith WD

更新日期：1999-11-01 00:00:00

abstract：:Cats were repeatedly inoculated with infective larvae of Brugia pahangi. On parasitological grounds they could be divided into 5 groups. Group I--most cats (some 70%) became microfilaraemic (mf+) and retained high levels of microfilariae (mf) in their blood for over 2 years. In some Group I cats mf counts stabilized a...

journal_title：Parasitology

authors： Denham DA,Medeiros F,Baldwin C,Kumar H,Midwinter IC,Birch DW,Smail A

更新日期：1992-06-01 00:00:00

abstract：:The importance of host heterogeneity in generating aggregation was investigated using Heligmosomoides polygyrus (Nematoda) in laboratory mice. Parameters of infection were compared between inbred and outbred mice, between primary and challenge infection protocols, and between gavage and natural exposure protocols, to ...

journal_title：Parasitology

authors： Tanguay GV,Scott ME

更新日期：1992-06-01 00:00:00

abstract：:The SICA[-] or non-agglutinable phenotype of Plasmodium knowlesi schizont-infected erythrocytes has been defined serologically but not biochemically. Similarly, non-cloned SICA[+] or agglutinable parasites have been shown serologically to express SICA or variant antigen(s) but the number and nature of such antigens ha...

journal_title：Parasitology

authors： Howard RJ,Barnwell JW

更新日期：1985-10-01 00:00:00

abstract：:Serology is an important tool for the diagnosis of alveolar echinococcosis (AE) in humans. In order to improve serodiagnostic performance, we have developed an in vitro-produced Echinococcus mulilocularis metacestode vesicle fluid (EmVF) antigen for application in an immunoblot assay. Immunoblot analysis of EmVF revea...

journal_title：Parasitology

authors： Müller N,Frei E,Nuñez S,Gottstein B

更新日期：2007-06-01 00:00:00

abstract：:Biochemical characterization of 137 Leishmania braziliensis isolates from South and Central America, and from selected endemic foci in Bolivia, Brazil and Colombia, performed by isoenzymatic electrophoresis using 10 enzymatic systems, showed a high enzymatic polymorphism (44 zymodemes obtained) based on the variation ...

journal_title：Parasitology

authors： Chouicha N,Lanotte G,Pratlong F,Cuba Cuba CA,Velez ID,Dedet JP

更新日期：1997-10-01 00:00:00

abstract：:DNA barcoding is now a common tool in parasitology and epidemiology, which require good methods for identification not only of parasites and pathogens but vectors and reservoirs. This special issue presents some advances and challenges in barcoding of microbes, parasites, and their vectors and reservoirs. DNA barcodin...

journal_title：Parasitology

authors： Morand S

更新日期：2018-04-01 00:00:00

abstract：:Merocyanin 540 (Mc540) is a fluorescent compound which is thought to bind to membranes in which there are substantial amounts of lipid in the lipid-crystalline phase. It is shown here to be of value in detecting the transformation by both mechanical and skin-penetration methods of the cercaria to the schistosomulum. T...

journal_title：Parasitology

authors： Foley M,Kusel JR,Garland PB

更新日期：1988-02-01 00:00:00