Discovery of new eunicellin-based diterpenoids from a Formosan soft coral Cladiella sp.

Abstract:

:A new eunicellin diterpenoid, cladieunicellin I (1), and a new natural eunicellin, litophynin I diacetate (2), were isolated from a Formosan soft coral identified as Cladiella sp. The structures of eunicellins 1 and 2 were elucidated by spectroscopic methods and by comparison of the spectral data with those of related analogues. Eunicellin 1 exhibited significant cytotoxicity toward the DLD-1 human colorectal adenocarcinoma cells.

journal_name

Mar Drugs

journal_title

Marine drugs

authors

Chen TH,Lu MC,Chang YC,Su YD,Chen YH,Lin NC,Fang LS,Wu YC,Sung PJ

doi

10.3390/md11114585

subject

Has Abstract

pub_date

2013-11-14 00:00:00

pages

4585-93

issue

11

issn

1660-3397

pii

md11114585

journal_volume

11

pub_type

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