Effect of 2.45 GHz microwave radiation on the fertility pattern in male mice.

Abstract:

:A number of studies have reported that male reproductive organs are susceptible to electromagnetic fields (EMFs). The aim of this study was to explore the effects of microwave radiation exposures on 6-8 weeks old male Swiss albino mice. Mice were divided into two groups: group I - sham-exposed (Control), and group II - microwaves-exposed (MWs). Mice were exposed to 2.45 GHz with power density 0.25 mW/cm2 and specific absorbtion rate (SAR) 0.09 W/kg. Exposure was given in Plexiglas cages for 2 h/day for 30 days. Results showed that 2.45 GHz microwave radiation resulted in a significant increase (p < 0.001) in catalase (CAT), malondialdehyde (MDA), reactive oxygen species (ROS) and decrease (p < 0.001) in the levels of glutathione peroxidase (GPx), testosterone and superoxide dismutase (SOD) (p < 0.05). Flow cytometer analysis of blood showed the formation of micronuclei in microwave-exposed group. Histopathological changes were also seen in seminiferous tubules of microwave-exposed group as compared to the sham-exposed group. It is concluded that 2.45 GHz microwave radiation exposure causes oxidative stress in testes and it may lead to detrimental and injurious effects on fertility potential of the male reproductive system of Swiss albino mice.

journal_name

Gen Physiol Biophys

authors

Jonwal C,Sisodia R,Saxena VK,Kesari KK

doi

10.4149/gpb_2017059

subject

Has Abstract

pub_date

2018-07-01 00:00:00

pages

453-460

issue

4

eissn

0231-5882

issn

1338-4325

journal_volume

37

pub_type

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