Epithelioid angiosarcoma of the spine: A case report of a rare bone tumor.

abstract：:Docetaxel is the current first-line treatment for castration-resistant prostate cancer (CRPC), following failure to respond to maximal androgen blockade (MAB). Patients who fail to respond to docetaxel may receive cabazitaxel or abiraterone; however, there are no recommendations on which of these two agents should be ...

journal_title：Oncology letters

authors： Marech I,Vacca A,Sivestris N,Gnoni A,Lorusso V

更新日期：2013-06-01 00:00:00

abstract：:Altered expression of microRNAs (miRNAs or miRs) contributes to lung carcinogenesis. The present study performed an in silico analysis of differentially expressed miRNAs in different peripheral blood samples from patients with various diseases vs. controls using the Gene Expression Omnibus (GEO) database data, and ass...

journal_title：Oncology letters

authors： Lu G,Fu D,Jia C,Chai L,Han Y,Liu J,Wu T,Xie R,Chang Z,Yang H,Luo P,Lv Z,Yu F,Zhong X,Ma Y

更新日期：2017-12-01 00:00:00

abstract：:Severe hemorrhage following a prostatectomy is a rare and serious complication. A 63-year-old male with severe hemorrhage following radical prostatectomy which led to hypovolemic shock presented at our department and was treated with superselective internal iliac arterial embolization. At 6 months follow-up, the patie...

journal_title：Oncology letters

authors： Cheng S,Xu L,Li G,Chen Y,Hu H,Zhang Z,Ding G

更新日期：2012-09-01 00:00:00

abstract：:In the present study, we investigated the correlation between the presence of occult neoplastic cells (ONCs) in lymph node sinuses and recurrence/metastasis of stage II/III gastric cancer in 164 patients who underwent radical curative resection. We calculated the five-year relapse-free survival rate (5Y-RFS) and five-...

journal_title：Oncology letters

authors： Sekido Y,Mukai M,Yamazaki M,Tajima T,Yamamoto S,Hasegawa S,Kishima K,Tajiri T,Nakamura N

更新日期：2014-01-01 00:00:00

abstract：:While erlotinib is primarily administered to patients with non-small cell lung cancer with sensitizing epidermal growth factor receptor (EGFR) mutations, it is also prescribed to patients with wild type (wt) EGFR in higher lines of treatment. However, there is no predictive marker for erlotinib efficacy in patients wi...

journal_title：Oncology letters

authors： Svaton M,Fiala O,Krakorova G,Blazek J,Hurdalkova K,Barinova M,Mukensnabl P,Pesek M

更新日期：2020-08-01 00:00:00

abstract：:The aim of the present study was to investigate the significance and values of 3.0T diffusion weighted imaging (DWI) to differentially diagnose benign and malignant space-occupying liver lesions. A total of 91 patients with liver space-occupying lesions (145 lesions) were admitted into Zhongnan Hospital of Wuhan Unive...

journal_title：Oncology letters

authors： Li R,Wu G,Wang R

更新日期：2018-02-01 00:00:00

abstract：:The detection of epidermal growth factor receptor (EGFR) mutations is necessary for the selection of suitable patients with non-small cell lung cancer (NSCLC) for treatment with EGFR tyrosine kinase inhibitors. Cytology specimens are known to be suitable for EGFR mutation detection, although tissue specimens should be...

journal_title：Oncology letters

authors： Asaka S,Yoshizawa A,Nakata R,Negishi T,Yamamoto H,Shiina T,Shigeto S,Matsuda K,Kobayashi Y,Honda T

更新日期：2018-02-01 00:00:00

abstract：:Pituitary tumor transforming gene 1 (PTTG11) is abundantly expressed in glioma. Our previous study demonstrated that the downregulation of PTTG11 gene expression significantly inhibited the proliferation, migration and invasion ability, and increased the apoptosis of SHG44 glioma cells. However, the molecular mechanis...

journal_title：Oncology letters

authors： Cui L,Xu L,Wang G,Wen J,Luo L,Zhao H,Chen S,Zheng M,Sun C,Jin X,Yang L

更新日期：2020-10-01 00:00:00

abstract：:Despite advancements in treatment regimens, the mortality rate of patients with oral tongue squamous cell carcinoma (OTSCC) is high. In addition, the signaling pathways and oncoproteins involved in OTSCC progression remain largely unknown. Therefore, the aim of the present study was to identify specific prognostic mar...

journal_title：Oncology letters

authors： Zhong P,Liu L,Shen A,Chen Z,Hu X,Cai Y,Lin J,Wang B,Li J,Chen Y,Peng J

更新日期：2019-12-01 00:00:00

abstract：:The current study presents a case of primary T-cell lymphoma (PTBL), unspecified, in a 27-year-old female. The patient received chemotherapy [cyclophosphamide, epirubicin, vindesine and prednisolone (CHOP) and VP-16 plus CHOP (ECHOP)] and autologous peripheral blood stem cell transplantation, however, relapse occurred...

journal_title：Oncology letters

authors： Gao Q,Zhang X,Xiang H,Ren G,Zheng Y

更新日期：2014-01-01 00:00:00

abstract：:The present study reviewed three patients with acute myeloid leukemia (AML) who had the specific genetic abnormality t(16;21)(p11;q22). To investigate the clinical and laboratory characteristics of AML with t(16;21)(p11;q22) translocation, the similarities and differences of clinical characteristics and laboratory exa...

journal_title：Oncology letters

authors： Zhang Z,Zou J,Li Y,Liu Z,Xu R,Tian W,Zhao Z,Sun H,Han J,Wang J,Zhang B,Ju Y

更新日期：2015-05-01 00:00:00

abstract：:Gelatinases are overexpressed in several types of maligancies and tumor stromal cells. Lidamycin is an enediyne antitumor antibiotic, which is composed of an apoprotein (LDP) and an active chromophore (AE). It is known that the heavy-chain complementarity-determining region-3 (CDR3) domain of scFv is important in anti...

journal_title：Oncology letters

authors： Zhong GS,Wu MN,Guo XF,Xu ZS,Zhang SH,Zhen YS

更新日期：2013-04-01 00:00:00

abstract：:The present case report describes the infrequent coexistence of squamous cell transformation and the epidermal growth factor receptor (EGFR) T790M mutation as resistance mechanisms to first line treatment with tyrosine kinase inhibitors. The patient was a 44-year-old female, diagnosed with a primitive advanced lung ad...

journal_title：Oncology letters

authors： Bruno R,Proietti A,Alì G,Puppo G,Ribechini A,Chella A,Fontanini G

更新日期：2017-11-01 00:00:00

abstract：:The present study examined the association between squamous cell carcinoma antigen (SCCA) expression and the response of patients with cervical cancer to docetaxel-carboplatin (DC) combination chemotherapy, in order to determine the prognostic potential of SCCA expression. A total of 21 patients were enrolled with sta...

journal_title：Oncology letters

authors： Chen P,Jiao L,Wang DB

更新日期：2017-03-01 00:00:00

abstract：:Nasopharyngeal carcinoma (NPC) is a common malignancy of the head and neck. The aim of the present study was to conduct an integrated bioinformatics analysis of differentially expressed genes (DEGs) and to explore the molecular mechanisms of NPC. Two profiling datasets, GSE12452 and GSE34573, were downloaded from the ...

journal_title：Oncology letters

authors： Zou Z,Gan S,Liu S,Li R,Huang J

更新日期：2019-07-01 00:00:00

abstract：:5,7-dihydroxy-3',4',6-trimethoxyflavone, commonly known as eupatilin, is a traditional Asian medicinal plant, which is mainly used for the treatment of gastritis, as well as its use as an anti-inflammatory agent. Eupatilin is a bioactive compound; however, its effects on osteosarcoma (OS) have remained to be elucidate...

journal_title：Oncology letters

authors： Li YY,Wu H,Dong YG,Lin BO,Xu G,Ma YB

更新日期：2015-10-01 00:00:00

abstract：:Survivin is expressed in the nucleus and/or cytoplasm of various malignant cells. Nuclear survivin is critical for the completion of mitosis, while cytoplasmic survivin functions as an inhibitor of apoptosis. The expression of survivin has been reported to be associated with the aggressiveness of certain types of canc...

journal_title：Oncology letters

authors： Hirano H,Maeda H,Yamaguchi T,Yokota S,Mori M,Sakoda S

更新日期：2015-09-01 00:00:00

abstract：:Ganglioneuromas (GNs) arising from neural crest sympathogonia are rare benign neurogenic tumors. The most commonly affected sites are the posterior mediastinum, the retroperitoneum and the adrenal gland. GNs often present as a solitary, painless and slow-growing mass, and multiple occurrences in the cervical region ar...

journal_title：Oncology letters

authors： Ma J,Liang L,Liu H

更新日期：2012-09-01 00:00:00

abstract：:The long non-coding RNA (lncRNA) plasmacytoma variant translocation 1 (PVT1) has been identified as an oncogene in numerous diseases, and aberrant lncRNA PVT1 expression has been associated with the development of cancer. However, the underlying mechanism by which lncRNA PVT1 affects cell invasion in esophageal cancer...

journal_title：Oncology letters

authors： Zheng X,Hu H,Li S

更新日期：2016-10-01 00:00:00

abstract：:S100A11, a member of S100 calcium-binding protein family, is associated with the numerous processes of tumorigenesis and metastasis. In the present study, the role of S100A11, and its possible underlying mechanisms in cell proliferation, apoptosis and cell cycle distribution in human pancreatic cancer were explored. I...

journal_title：Oncology letters

authors： Xiao M,Li T,Ji Y,Jiang F,Ni W,Zhu J,Bao B,Lu C,Ni R

更新日期：2018-01-01 00:00:00

abstract：:The aim of the present study was to perform a retrospective analysis to investigate the outcome and toxicity of radiation (RT) and chemoradiation (CRT) in elderly, inoperable patients >70 years old. Between 2003 and 2012, 1,024 patients with squamous cell carcinoma (SCC) of the esophagus were treated at the Department...

journal_title：Oncology letters

authors： Xu HY,DU ZD,Zhou L,Yu M,Ding ZY,Lu Y

更新日期：2014-01-01 00:00:00

abstract：:A growing body of evidence suggests that oncogenesis is associated with systemic inflammation. The present study investigated white blood cell and platelet indices, whose values change during the inflammatory response, in women with invasive ductal breast carcinoma. Preoperatively obtained white blood cell and platele...

journal_title：Oncology letters

authors： Mantas D,Kostakis ID,Machairas N,Markopoulos C

更新日期：2016-08-01 00:00:00

abstract：:Thyroid cancer is the most common malignant endocrine tumor, with significant morbidity and mortality. Bovine myeloid antimicrobial peptide 28 (BMAP-28) is a cathelicidin that is found in bovine neutrophils. In the present study, the effect and relative mechanism of BMAP-28 on the human thyroid cancer TT cell line in ...

journal_title：Oncology letters

authors： Zhang D,Wan L,Zhang J,Liu C,Sun H

更新日期：2015-10-01 00:00:00

abstract：:Abnormalities in proto-oncogene B-Raf (BRAF) are typical in several subgroups of gliomas, including pilocytic astrocytomas, optic nerve gliomas, pleomorphic xanthoastrocytomas (PXA), anaplastic PXAs and gangliogliomas. However, they are rarely reported in adult gliomas. BRAF alterations are frequent in a distinct vari...

journal_title：Oncology letters

authors： Tosuner Z,Geçer MÖ,Hatiboğlu MA,Abdallah A,Turna S

更新日期：2018-08-01 00:00:00

abstract：:The present study aimed to investigate the feasibility of using ecto-mesenchymal stem cell (EMSC)-derived dendritic cells (DCs) for glioma immunotherapy following infection by a recombinant adenovirus containing the melanoma-associated antigen D4a (MAGE-D4a) gene. The ex vivo cultured EMSCs were infected by the adenov...

journal_title：Oncology letters

authors： Hu S,Li B,Shen X,Zhang R,Gao D,Guo Q,Jin Y,Fei Z

更新日期：2016-04-01 00:00:00

abstract：:High-fat diet induced obesity was associated with more aggressive prostate cancer. Recent research has demonstrated that integrin-linked kinase (ILK), β-parvin and downstream cofilin 1 jointly affected cancer progression. Meanwhile, these proteins were also involved in energy metabolism. Therefore, the present study w...

journal_title：Oncology letters

authors： Hu MB,Hu JM,Jiang LR,Yang T,Zhu WH,Hu Y,Wu XB,Jiang HW,Ding Q

更新日期：2018-10-01 00:00:00

abstract：:With the growing requirement for novel prognostic biomarkers for pancreatic cancer, many studies have focused on clinical and/or genomic variables. Although many studies have been performed, carbohydrate antigen 19-9 is the only biomarker in clinical use. Therefore, the present study examined whether γ-secretase genes...

journal_title：Oncology letters

authors： Jeon YH,Ha M,Kim SW,Kim MJ,Lee CS,Oh CK,Han ME,Oh SO,Kim YH

更新日期：2019-05-01 00:00:00

abstract：:The prognosis for patients with head and neck cancer (HNC) remains poor, owing to uncontrolled tumor invasion and metastasis. Epithelial-mesenchymal transition (EMT) serves an important role in this invasion and metastasis, and transient receptor potential polycystic 2 (TRPP2) enhances metastasis and invasion by regul...

journal_title：Oncology letters

authors： Wang C,Chen L,Huang Y,Li K,Jinye A,Fan T,Zhao R,Xia X,Shen B,Du J,Liu Y

更新日期：2019-02-01 00:00:00

abstract：:Retroperitoneal liposarcoma is a rare tumor with an incidence of 2.5 per million individuals. Early diagnosis is difficult as there is an absence of specific clinical presentations. The present case study reports a patient diagnosed with retroperitoneal liposarcoma who was treated by complete surgical resection and re...

journal_title：Oncology letters

authors： Zhang WD,Liu DR,Que RS,Zhou CB,Zhan CN,Zhao JG,Chen LI

更新日期：2015-07-01 00:00:00

abstract：:The global incidence of prostate cancer (PCa) has been increasing in recent years. Meanwhile, some studies have indicated the association between malignancies, such as lung and gastric cancer and PCa, and microRNAs (miRNAs). The present study was designed to assess the prognostic value of miR-92b-3p in patients with P...

journal_title：Oncology letters

authors： Wang G,Cheng B,Jia R,Tan B,Liu W

更新日期：2021-01-01 00:00:00