Differential expressions of integrin-linked kinase, β-parvin and cofilin 1 in high-fat diet induced prostate cancer progression in a transgenic mouse model.

abstract：:The clinical use of doxorubicin (DOX), a potent antineoplastic agent, is limited by its serious side-effects, which include acute and chronic cumulative dose-related cardiotoxicity. Berberine (BER), a botanical alkaloid, has been reported to possess cardioprotective and antitumor effects. The 3-(4,5-dimethyl-2-thiazol...

journal_title：Oncology letters

authors： Tong N,Zhang J,Chen Y,Li Z,Luo Y,Zuo H,Zhao X

更新日期：2012-06-01 00:00:00

abstract：:Patients with renal medullary carcinoma (RMC) have a poor prognosis, usually due to late diagnosis. Computed tomography (CT) analysis may aid the differentiation between RMC and other types of renal cell carcinoma, in order to establish an accurate early diagnosis. There is a limited number of reports in the literatur...

journal_title：Oncology letters

authors： Shi Z,Zhuang Q,You R,Li Y,Li J,Cao D

更新日期：2016-01-01 00:00:00

abstract：:Hepatocellular carcinoma (HCC) metastases in the mediastinum are rare, particularly under the arch of the aorta. The present study describes the case of a 30-year-old male patient who presented with back pain and hoarseness for 2 months due to lymph node metastasis of HCC. The patient had undergone right hepatic lobec...

journal_title：Oncology letters

authors： Xu L,Xue F,Wang B,Yan D,Ding W,Yin J,Yi C,Wang W

更新日期：2016-08-01 00:00:00

abstract：:Bladder cancer (BC) is one of the most common urogenital malignancies. However, present studies of its multiple gene interaction and cellular pathways remain unable to accurately verify the genesis and the development of BC. The aim of the present study was to investigate the genetic signatures of BC and identify its ...

journal_title：Oncology letters

authors： Yan M,Jing X,Liu Y,Cui X

更新日期：2018-09-01 00:00:00

abstract：:In this study, we report the cytogenetic analysis of a 31-year-old male with a rare translocation between chromosomes 1 and 16 and inversion of chromosome 5 in CD99-positive soft tissue sarcoma of the thigh, which metastasized to the lung. Histologically, the tumor showed ovoid or short-spindle atypical cells with pos...

journal_title：Oncology letters

authors： Kanamori M,Suzuki K,Yasuda T,Hori T

更新日期：2012-06-01 00:00:00

abstract：:Oncological and functional prognostic factors for patients with foot sarcomas have yet to be clarified. This study was undertaken to identify the prognostic factors for oncological and functional outcomes and the significance of adjuvant radiotherapy in achieving local control in patients with foot sarcomas. We review...

journal_title：Oncology letters

authors： Kozawa E,Nishida Y,Nakashima H,Tsukushi S,Toriyama K,Kamei Y,Ishiguro N

更新日期：2012-01-01 00:00:00

abstract：:Colorectal cancer (CRC) is the third most common cancer worldwide and its treatment remains a challenge. Effective control of cell survival and proliferation is critical in the prevention of oncogenesis and successful treatment of cancer. Long non-coding RNAs (lncRNAs) have emerged as primary regulators of carcinogene...

journal_title：Oncology letters

authors： Yang Y,Shen Z,Yan Y,Wang B,Zhang J,Shen C,Li T,Ye C,Gao Z,Peng G,Ye Y,Jiang K,Wang S

更新日期：2017-05-01 00:00:00

abstract：:The present study aimed to investigate the expression levels and clinical value of miR-365 and miR-25 in serum of patients with non-small cell lung cancer (NSCLC). Patients (180) diagnosed with NSCLC at the Affiliated Hospital of Guangdong Medical University from July 2011 to December 2013 were used as the experimenta...

journal_title：Oncology letters

authors： Huang D,Ou W,Tong H,Peng M,Ou Y,Song Z

更新日期：2020-11-01 00:00:00

abstract：:Gap junctions (GJs) serve the principal role in the antineoplastic (cytotoxicity and induced apoptosis) effect of chemical drugs. The aim of the present study was to determine the effect of GJ intercellular communication (GJIC) composed of connexin 43 (Cx43) on adriamycin cytotoxicity in breast cancer cells. Four cell...

journal_title：Oncology letters

authors： Jiang G,Dong S,Yu M,Han X,Zheng C,Zhu X,Tong X

更新日期：2017-02-01 00:00:00

abstract：:The prognosis following surgical treatment of gastric carcinoma (GC) or gastroesophageal junction (GEJ) adenocarcinoma remains poor. Although adjuvant chemo-radiotherapy with 5-fluorouracil has been shown to be beneficial, a high rate of distant failure has been reported. Thus, the toxicity profile and efficacy of an ...

journal_title：Oncology letters

authors： Shulman K,Haim N,Wollner M,Bernstein Z,Abdah-Bortnyak R,Bar-Sela G

更新日期：2012-05-01 00:00:00

abstract：:KG-1 and its less differentiated subline KG-1a are leukemia cell lines used in research in a number of laboratories. The karyotypes of the two lines were initially identical. In the following years, further analysis revealed that the cell lines had acquired additional karyotypical abnormalities and differed in the pre...

journal_title：Oncology letters

authors： Pelliccia F,Ubertini V,Bosco N

更新日期：2012-08-01 00:00:00

abstract：:The aim of this study was to construct the eukaryotic expression vector pEGFP-N1-hPer2 and assess its expression in the human osteosarcoma cell line MG63. Total mRNA was extracted from human osteosarcoma MG63 cells, the human period 2 (hPer2) gene was obtained by reverse transcription-polymerase chain reaction (RT-PCR...

journal_title：Oncology letters

authors： Cheng A,Zhang Y,Mei H,Fang S,Ji P,Yang J,Yu L,Guo W

更新日期：2016-04-01 00:00:00

abstract：:MicroRNAs (miRs) are an emerging class of non-coding, endogenous and small RNA molecules that serve important functions in tumorigenesis and development. The present study investigated the expression, functions and molecular mechanism underlying miR-205 in hepatocellular carcinoma. miR-205 was downregulated in hepatoc...

journal_title：Oncology letters

authors： Zhao X,Zhou S,Wang D,He W,Li J,Zhang S

更新日期：2018-08-01 00:00:00

abstract：:This study investigated energy metabolism and its association with inflammatory cytokines and appetite- regulating hormones in patients with gastrointestinal cancer. Subjects were inpatients scheduled to undergo therapeutic intervention for diagnosed gastrointestinal cancer. Nutritional status on admission was assesse...

journal_title：Oncology letters

authors： Shinsyu A,Bamba S,Kurihara M,Matsumoto H,Sonoda A,Inatomi O,Andoh A,Takebayashi K,Kojima M,Iida H,Tani M,Sasaki M

更新日期：2020-08-01 00:00:00

abstract：:Clear cell renal cell carcinoma (ccRCC) exhibits the highest mortality among all urological malignancies. The investigation of the potential disease progression markers can improve ccRCC diagnosis and treatment. Gene associated with retinoid-interferon-induced mortality-19 (GRIM-19) is involved in carcinogenesis and c...

journal_title：Oncology letters

authors： Yan N,Feng X,Jiang S,Sun W,Sun MZ,Liu S

更新日期：2020-06-01 00:00:00

abstract：:Gastric cancer is a pathological process of an accumulation of multigene and multistage mutations. A new gene segment, MDSCBC11, has been previously obtained using a gene chip and is negatively associated with gastric cancer. The present study aimed to clone the full cDNA sequence of the MDSCBC11 segment and to detect...

journal_title：Oncology letters

authors： Gan R,Liu X,Zhou Y,Tan Y,Liu H,Li G,Tang Y,Xie H

更新日期：2013-12-01 00:00:00

abstract：:The aim of the present study was to investigate the significance and values of 3.0T diffusion weighted imaging (DWI) to differentially diagnose benign and malignant space-occupying liver lesions. A total of 91 patients with liver space-occupying lesions (145 lesions) were admitted into Zhongnan Hospital of Wuhan Unive...

journal_title：Oncology letters

authors： Li R,Wu G,Wang R

更新日期：2018-02-01 00:00:00

abstract：:Retroperitoneal tumors are lesions with diverse pathological subtypes that originate from the retroperitoneal space; ~40% of these tumors are benign. Due to such lesions often surrounding and associating with vital abdominal blood vessels, a complete surgical resection is difficult. The current study presents a novel ...

journal_title：Oncology letters

authors： Wan Z,Yin T,Chen H,Li D

更新日期：2016-05-01 00:00:00

abstract：:The value of interventional ultrasound in the diagnosis and treatment of submucous myoma of the uterus was assessed to study the ultrasonographic features of modified sonohysterography for submucous polyp of uterus. A total of 25 patients diagnosed preliminarily as submucous myoma of the uterus via conventional ultras...

journal_title：Oncology letters

authors： Liang B,Xie YG,Xu XP,Hu CH

更新日期：2018-05-01 00:00:00

abstract：:A 77-year-old female, with proptosis, reduced eye motility and diplopia which had developed over two to three months and a 69-year-old female with proptosis, oedema of the eyelid, reduced motility and ptosis, which had developed over three weeks, are presented in the present study. Computed tomography scans revealed i...

journal_title：Oncology letters

authors： Nickelsen MN,VON Holstein S,Hansen AB,Prause JU,Heegaard S

更新日期：2015-08-01 00:00:00

abstract：:The aim of the present study was to investigate the expression of transactivation response RNA-binding protein (TARBP)1 and its clinical significance in human non-small-cell lung cancer (NSCLC). TARBP1 expression at the mRNA level was detected by reverse transcription-quantitative polymerase chain reaction (RT-qPCR) i...

journal_title：Oncology letters

authors： Ye J,Wang J,Zhang N,Liu Y,Tan L,Xu L

更新日期：2018-05-01 00:00:00

abstract：:Our previous study demonstrated that the 2-benzyloxybenzaldehyde analog CCY-1a-E2 is a potent compound against HL-60 human leukemia cell lines. To investigate the potential therapeutic application of CCY-1a-E2 for leukemia, we analyzed the antileukemic effects and safety of CCY-1a-E2 in the BALB/c mouse WEHI-3 allogra...

journal_title：Oncology letters

authors： Lin C,Yang JS,Tsai SC,Lin CF,Lee MR

更新日期：2013-03-01 00:00:00

abstract：:Osteosarcoma (OS) is the most common form of bone malignancy in children and adolescents. A class of molecules known as microRNAs (miRNAs) have been routinely associated in the development and progression of OS. The present study was centered on the less well-known miRNA, miRNA (miR)-150, and its role in OS was invest...

journal_title：Oncology letters

authors： Li CH,Yu TB,Qiu HW,Zhao X,Zhou CL,Qi C

更新日期：2017-04-01 00:00:00

abstract：:Few reports have explored laparoscopic adnexal tumorectomy as a treatment for large and symptomatic ovarian leiomyomas during pregnancy. The current study presents the case of a patient with a large and symptomatic ovarian leiomyoma at 14 weeks of pregnancy. A laparoscopic adnexal tumorectomy was performed without com...

journal_title：Oncology letters

authors： Zhao X,Chen L,Zeng W,Jin B,DU W

更新日期：2014-12-01 00:00:00

abstract：:Peritumoral edema (PTE), one of the main characteristics of malignant glioma, is a significant contributor to the morbidity and mortality from glioma, however, a recent systematic review suggested that controversy remains with regard to its prognostic value. To further determine whether PTE was a potential prognostic ...

journal_title：Oncology letters

authors： Wu CX,Lin GS,Lin ZX,Zhang JD,Chen L,Liu SY,Tang WL,Qiu XX,Zhou CF

更新日期：2015-11-01 00:00:00

abstract：:Atorvastatin (ATST), a drug commonly used to reduce the levels of cholesterol and low-density lipoproteins, is a prospective agent for the prevention of colorectal cancer in patients with hyperlipidemia. ATST in combination with functional components is a promising strategy for cancer chemoprevention. In the present s...

journal_title：Oncology letters

authors： Zhou M,Zheng J,Bi J,Wu X,Lyu J,Gao K

更新日期：2018-02-01 00:00:00

abstract：:Value of MRI diffusion-weighted imaging (MRI DWI) combined with PET/CT in the diagnosis and staging of stomach cancer (SC) was investigated. A retrospective analysis was performed on 160 patients with SC diagnosed by pathological biopsy in The Affiliated Yantai Yuhuangding Hospital of Qingdao University from March 201...

journal_title：Oncology letters

authors： Sui Y,Zou Z,Li F,Hao C

更新日期：2019-07-01 00:00:00

abstract：:Sigma-1 receptor (sigma-1R), a 25-kDa integral membrane protein, is expressed at a high density in various tumor cell lines and its ligands mediate tumor cell proliferation. However, the effect of this receptor on proliferation and the associated intracellular molecules in tumors remains unclear. The present study aim...

journal_title：Oncology letters

authors： Wu Y,Bai X,Li X,Zhu C,Wu ZP

更新日期：2018-11-01 00:00:00

abstract：:Carcinoid tumors are neuroendocrine neoplasms derived from enterochromaffin cells. Skeletal metastases from carcinoid tumors are considered to be extremely rare. In this study, we present two cases of carcinoid tumors that metastasized to the bone. Furthermore, we review 50 published case reports and reveal the featur...

journal_title：Oncology letters

authors： Hori T,Yasuda T,Suzuki K,Kanamori M,Kimura T

更新日期：2012-05-01 00:00:00

abstract：:Long non-coding RNAs (lncRNAs) are recently identified regulators in tumorigenesis and tumour progression. BRAF-activated lncRNA (BANCR) is overexpressed in melanoma and has a potential functional role in melanoma cell migration. However, little is known concerning the role of BANCR in the development of colorectal ca...

journal_title：Oncology letters

authors： Guo Q,Zhao Y,Chen J,Hu J,Wang S,Zhang D,Sun Y

更新日期：2014-08-01 00:00:00