Abstract:
:Ganglioneuromas (GNs) arising from neural crest sympathogonia are rare benign neurogenic tumors. The most commonly affected sites are the posterior mediastinum, the retroperitoneum and the adrenal gland. GNs often present as a solitary, painless and slow-growing mass, and multiple occurrences in the cervical region are extremely rare. Here, we report a case of massive multiple cervical GN in a 4-year-old girl, and review cases of cervical GN that have been reported in the past 10 years. The results demonstrated that cervical GN, compared to other sites, is seldom secretory. The signs and symptoms of cervical GN are unspecific; the ultimate diagnosis of GN depends on pathological examination. Fine-needle aspiration biopsy has limited value in diagnosis. Surgical excision is the treatment of choice and the prognosis is excellent even in cases where complete excision cannot be achieved. Furthermore, GNs should be considered in patients with multiple masses in the neck.
journal_name
Oncol Lettjournal_title
Oncology lettersauthors
Ma J,Liang L,Liu Hdoi
10.3892/ol.2012.767subject
Has Abstractpub_date
2012-09-01 00:00:00pages
509-512issue
3eissn
1792-1074issn
1792-1082pii
ol-04-03-0509journal_volume
4pub_type
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