Giant malignant mesothelioma in the upper mediastinum: A case report.

Abstract:

:Malignant mesothelioma in the mediastinum is rare and the majority of known cases have been reported as 'localized mesothelioma'. The present study reports a case of an upper mediastinal tumor, which was diagnosed through thoracoscopic surgery and surgical biopsies of the mass. A computed tomography scan revealed a giant upper mediastinal tumor, adjacent to the aortic arch, trachea, superior vena cava and left pulmonary artery. The vessels in the mediastinum were compressed and were shifted to the lower right. The trachea became stenotic and a small amount of bilateral pleural effusion was observed. The mass was relatively well encapsulated. There was no pleural thickening or clearly swollen lymph nodes in the mediastinum. The histopathological and immunohistochemical examinations of the tumor verified the diagnosis of a malignant mesothelioma. The tumor was demonstrated to be derived from the mediastinal pleural mesothelium cells. The patient received pemetrexed disodium and cisplatin combination chemotherapy for four cycles. At present, the patient is undergoing follow-up.

journal_name

Oncol Lett

journal_title

Oncology letters

authors

Zhang S,Song P,Zhang B

doi

10.3892/ol.2013.1333

subject

Has Abstract

pub_date

2013-07-01 00:00:00

pages

181-184

issue

1

eissn

1792-1074

issn

1792-1082

pii

ol-06-01-0181

journal_volume

6

pub_type

杂志文章
  • Diagnosis of bladder cancer from the voided urine specimens using multi-target fluorescence in situ hybridization.

    abstract::The present study aimed to evaluate the diagnostic value of chromosomal analysis by fluorescence in situ hybridization (FISH) for bladder cancer in light of the histological diagnosis. Several valuable observations using FISH technologies in voided urine cells were also reported. The multi-target FISH-containing probe...

    journal_title:Oncology letters

    pub_type: 杂志文章

    doi:10.3892/ol.2013.1744

    authors: Ke Z,Lai Y,Ma X,Lil S,Huang W

    更新日期:2014-02-01 00:00:00

  • Camptothecin inhibits the progression of NPC by regulating TGF-β-induced activation of the PI3K/AKT signaling pathway.

    abstract::Nasopharyngeal carcinoma (NPC) is a type of cancer that is characterized by increased invasiveness, metastatic potential and tumor recurrence. Camptothecin has been demonstrated to exhibit anticancer activity. However, the potential underlying molecular mechanisms mediated by camptothecin in NPC cells remain elusive. ...

    journal_title:Oncology letters

    pub_type: 杂志文章

    doi:10.3892/ol.2018.8688

    authors: Li BS,Huang JY,Guan J,Chen LH

    更新日期:2018-07-01 00:00:00

  • Tanshinone IIA inhibits proliferation and induces apoptosis of human nasopharyngeal carcinoma cells via p53-cyclin B1/CDC2.

    abstract::Tanshinone IIA exhibits natural antioxidative and antineoplastic activity. However, to the best of our knowledge, the effects of tanshinone IIA on human nasopharyngeal carcinoma cells remains unknown. The present study aimed to investigate whether tanshinone IIA inhibits proliferation and induces apoptosis of human na...

    journal_title:Oncology letters

    pub_type: 杂志文章

    doi:10.3892/ol.2019.10658

    authors: Liu B,Liu L,Zang A,Song Z,Yang H,Wang Z,Shang Y,Ma T,Zhang Y

    更新日期:2019-09-01 00:00:00

  • Erratum: A novel t(9;22;11) translocation involving 11q24 in a patient with chronic myeloid leukemia: A case report.

    abstract::[This corrects the article DOI: 10.3892/ol.2017.5668.]. ...

    journal_title:Oncology letters

    pub_type: 杂志文章,已发布勘误

    doi:10.3892/ol.2017.6875

    authors: Lee J,Kim DS,Lee HS,Choi SI,Cho YG

    更新日期:2017-11-01 00:00:00

  • Synovial sarcoma individual chemotherapy directed by collagen gel droplet embedded culture drug sensitivity test: A case report.

    abstract::The collagen gel droplet embedded culture-drug sensitivity test (CD-DST) is an anticancer drug sensitivity test developed about 10 years ago. This study reports the application of this test in the choice of neoadjuvant chemotherapy for the treatment of one patient with a large synovial sarcoma in the right shank. A 28...

    journal_title:Oncology letters

    pub_type: 杂志文章

    doi:10.3892/ol_00000157

    authors: Gu F,Ma Y,Fan Y,Lang R,Ding T,Hao X,Gong Y,Kobayahsi H,Fang Z,Fu L

    更新日期:2010-09-01 00:00:00

  • Human papillomavirus infection induces NF-κB activation in cervical cancer: A comparison with penile cancer.

    abstract::This study aimed to determine the relationship between human papillomavirus (HPV) and nuclear factor-κB (NF-κB) in cervical cancer using 62 tissues of cervical cancer, and to compare the findings to penile cancer. HPV-DNA integration is a crucial factor for malignant transformation in cervical cancer and can be identi...

    journal_title:Oncology letters

    pub_type: 杂志文章

    doi:10.3892/ol.2010.207

    authors: Senba M,Buziba N,Mori N,Fujita S,Morimoto K,Wada A,Toriyama K

    更新日期:2011-01-01 00:00:00

  • Diagnosis and treatment of submucous myoma of the uterus with interventional ultrasound.

    abstract::The value of interventional ultrasound in the diagnosis and treatment of submucous myoma of the uterus was assessed to study the ultrasonographic features of modified sonohysterography for submucous polyp of uterus. A total of 25 patients diagnosed preliminarily as submucous myoma of the uterus via conventional ultras...

    journal_title:Oncology letters

    pub_type: 杂志文章

    doi:10.3892/ol.2018.8122

    authors: Liang B,Xie YG,Xu XP,Hu CH

    更新日期:2018-05-01 00:00:00

  • Evaluation of the optimal dosage of S-1 in adjuvant SOX chemotherapy for gastric cancer.

    abstract::Gastric cancer (GC) is the second leading cause of cancer-related mortality worldwide. The usual treatment of GC consists of surgery with additional adjuvant chemotherapy. In the present study, the feasibility and safety of adjuvant S-1 plus oxaliplatin (SOX) chemotherapy for patients with GC and the optimal dosage of...

    journal_title:Oncology letters

    pub_type: 杂志文章

    doi:10.3892/ol.2014.2821

    authors: Yang L,Yang Y,Qin Q,Zhou A,Zhao J,Wang J,Shu C,Yuan X,Hu S

    更新日期:2015-03-01 00:00:00

  • MicroRNA-125a-3p downregulation correlates with tumorigenesis and poor prognosis in patients with non-small cell lung cancer.

    abstract::MicroRNA (miR)-125a-3p is derived from the 3'-end of pre-miR-125a, which is associated with several types of cancer, such as gastric and prostate cancer, and glioma. The aim of the present study was to identify the prognostic significance of miR-125a-3p expression levels in patients with NSCLC. The gene expression omn...

    journal_title:Oncology letters

    pub_type: 杂志文章

    doi:10.3892/ol.2017.6809

    authors: Hou L,Luo P,Ma Y,Jia C,Yu F,Lv Z,Wu C,Fu D

    更新日期:2017-10-01 00:00:00

  • High expression of ZEB1 correlates with liver metastasis and poor prognosis in colorectal cancer.

    abstract::Zinc finger E-box binding homeobox 1 (ZEB1) has been shown to promote invasion and metastasis in several types of human cancer and to have a prognostic role in certain cancers. However, the clinical significance of ZEB1 in colorectal cancer (CRC) has not been sufficiently investigated. This study aimed to address this...

    journal_title:Oncology letters

    pub_type: 杂志文章

    doi:10.3892/ol.2012.1026

    authors: Zhang GJ,Zhou T,Tian HP,Liu ZL,Xia SS

    更新日期:2013-02-01 00:00:00

  • MicroRNA-335 is downregulated in papillary thyroid cancer and suppresses cancer cell growth, migration and invasion by directly targeting ZEB2.

    abstract::MicroRNAs (miRs) are a group of short, endogenous, non-protein-coding and single-stranded RNAs that regulate gene expression by binding to the 3'-untranslated region (3'UTR) of mRNAs, which results in their degradation or translational repression. The aim of the present study was to investigate the expression and func...

    journal_title:Oncology letters

    pub_type: 杂志文章

    doi:10.3892/ol.2017.7126

    authors: Kan Q,Su Y,Yang H

    更新日期:2017-12-01 00:00:00

  • Identification and functional characterization of long non-coding RNAs in human gastric cancer.

    abstract::Abnormal regulation of long non-coding RNAs (lncRNAs) appears to be a primary feature of numerous types of human cancer. However, the association between the dysregulation of lncRNAs and functional alterations in gastric cancer (GC) remains unclear. In previous studies, we applied microarray and bioinformatics analyse...

    journal_title:Oncology letters

    pub_type: 杂志文章

    doi:10.3892/ol.2018.8369

    authors: Li CY,Liang GY,Yao WZ,Sui J,Shen X,Zhang YQ,Ma SM,Ye YC,Zhang ZY,Zhang WH,Yin LH,Pu YP

    更新日期:2018-06-01 00:00:00

  • Statins and pancreatic cancer.

    abstract::Pancreatic cancer remains among the most lethal cancers, despite ongoing advances in treatment for all stages of the disease. Disease prevention represents another opportunity to improve patient outcome, with metabolic syndrome and its components, such as diabetes, obesity and dyslipidemia, having been recognized as m...

    journal_title:Oncology letters

    pub_type: 杂志文章

    doi:10.3892/ol.2017.5572

    authors: Gong J,Sachdev E,Robbins LA,Lin E,Hendifar AE,Mita MM

    更新日期:2017-03-01 00:00:00

  • Rechallenge of carboplatin-gemcitabine based chemotherapy for rapidly progressing metastatic collecting duct carcinoma of the kidney leading to a delayed and durable complete response: A case report.

    abstract::Renal collecting duct carcinoma (CDC) is a rare and highly aggressive subtype of kidney cancer with poor prognosis. We report a case of one patient, who was successfully treated with gemcitabine-platin based chemotherapy for polymetastatic renal CDC, and experienced a late and prolonged complete remission. In June 201...

    journal_title:Oncology letters

    pub_type: 杂志文章

    doi:10.3892/ol.2019.9991

    authors: Dano D,Delteil C,Boissier R,Delaporte V,Habert P,Salas S,Duffaud F,Deville JL

    更新日期:2019-03-01 00:00:00

  • Advanced choroidal melanoma with a desirable aesthetic outcome after enucleation: A case report.

    abstract::Choroidal melanoma is a rare ocular tumor. The present study reports the case of a 66-year-old male who presented with chronic headache and progressive visual loss. Physical eye examination and combined A- and B-mode ultrasonography detected choroidal melanoma. Due to tumor characteristics the eye was enucleated resto...

    journal_title:Oncology letters

    pub_type: 杂志文章

    doi:10.3892/ol.2018.8661

    authors: Terzidou C,Trivli A,Dalianis G,Apessou D,Spandidos DA,Goulielmos GN

    更新日期:2018-07-01 00:00:00

  • Effects of resveratrol on vascular endothelial growth factor expression in osteosarcoma cells and cell proliferation.

    abstract::The aim of the current study was to investigate the effects of resveratrol (Res) on vascular endothelial growth factor (VEGF) expression and cell proliferation in the human osteosarcoma cell line U20S. U20S cells were treated with Res at various concentrations (0, 10, 20 and 40 μmol/l) for various times (24, 48 and 72...

    journal_title:Oncology letters

    pub_type: 杂志文章

    doi:10.3892/ol.2012.824

    authors: Liu Z,Li Y,Yang R

    更新日期:2012-10-01 00:00:00

  • Role of wild-type p53-induced phosphatase 1 in cancer.

    abstract::Wild-type p53-induced phosphatase (Wip1) is a member of the protein phosphatase type 2C family and is an established oncogene due to its dephosphorylation of several tumor suppressors and negative control of the DNA damage response system. It has been reported to dephosphorylate p53, ataxia telangiectasia mutated, che...

    journal_title:Oncology letters

    pub_type: 杂志文章

    doi:10.3892/ol.2017.6685

    authors: Wang ZP,Tian Y,Lin J

    更新日期:2017-10-01 00:00:00

  • Effect of overexpression of HOX genes on its invasive tendency in cerebral glioma.

    abstract::Transcription factors encoded by HOX genes are vital in the determination of cell fate and identity during embryonic development. In certain malignancies, HOX genes also behave as oncogenes. The present study demonstrated suppression of the invasive tendency of glioblastoma multiforme U-118 and U-138 cells by the intr...

    journal_title:Oncology letters

    pub_type: 杂志文章

    doi:10.3892/ol.2015.3893

    authors: Guo YB,Shao YM,Chen J,Xu SB,Zhang XD,Wang MR,Liu HY

    更新日期:2016-01-01 00:00:00

  • Multifocal epithelial hyperplasia: A potentially precancerous disease? (Review).

    abstract::Multifocal epithelial hyperplasia (MEH), also known as Heck's disease, manifests as a papulonodular lesion in the oral mucosa and has been associated with the human papillomavirus, a virus related to various precancerous diseases in the oral cavity. It has a predisposition for the female gender and for children. Altho...

    journal_title:Oncology letters

    pub_type: 杂志文章

    doi:10.3892/ol.2011.465

    authors: Bascones-Martínez A,Cok S,Bascones-Ilundáin C,Arias-Herrera S,Gomez-Font R,Bascones-Ilundáin J

    更新日期:2012-02-01 00:00:00

  • Stromal fibroblast activation and their potential association with uterine fibroids (Review).

    abstract::Uterine fibroids are the most common type of benign, gynecologic neoplasm and are the primary indication for performance of a hysterectomy, accounting for >200,000 hysterectomies annually in the USA. At present, females are younger and exhibit larger leiomyomas at the time of diagnosis. Cancer-associated fibroblasts i...

    journal_title:Oncology letters

    pub_type: 杂志文章

    doi:10.3892/ol.2014.2225

    authors: Zheng LH,Cai FF,Ge I,Biskup E,Cheng ZP

    更新日期:2014-08-01 00:00:00

  • Usefulness of PET/CT in the diagnosis of recurrent or metastasized differentiated thyroid carcinoma.

    abstract::The aim of the present study was to determine the usefulness of the positron emission tomography/computed tomography (PET/CT) with 18F-fluorodeoxyglucose (FDG) in the detection of recurrence or metastasization of differentiated thyroid carcinoma (DTC) in patients with abnormal thyroglobulin levels and negative finding...

    journal_title:Oncology letters

    pub_type: 杂志文章

    doi:10.3892/ol.2016.4229

    authors: Lu CZ,Cao SS,Wang W,Liu J,Fu N,Lu F

    更新日期:2016-04-01 00:00:00

  • Antitumor and antimetastasis effects of carboplatin liposomes with polyethylene glycol-2000 on SGC-7901 gastric cell-bearing nude mice.

    abstract::The present study aimed to analyze the characteristics of polyethylene glycol (PEG)ylated carboplatin liposomes (PL-CBPs), including size, stability, their release, entrapping and loading efficiencies, and their antitumor and antimetastatic effects on the lymph nodes. The PL-CBPs were prepared using PEG-2000 with the ...

    journal_title:Oncology letters

    pub_type: 杂志文章

    doi:10.3892/ol.2014.2494

    authors: Zhang J,Huang C,Huang H

    更新日期:2014-11-01 00:00:00

  • miR-202 acts as a potential tumor suppressor in breast cancer.

    abstract::Breast cancer affects ~10% of women worldwide and is responsible for ~12% of all cancer-associated mortalities. Breast cancer is more prone to metastasis compared with other types of cancer. Up to 5% of patients with breast cancer present with incurable metastasis and an additional 10-15% of patients develop metastase...

    journal_title:Oncology letters

    pub_type: 杂志文章

    doi:10.3892/ol.2018.8726

    authors: Gao S,Cao C,Dai Q,Chen J,Tu J

    更新日期:2018-07-01 00:00:00

  • Effects of silencing RIP1 with siRNA on the biological behavior of the LoVo human colon cancer cell line.

    abstract::The present study aimed to investigate the effects of silencing RIP1 by small interfering RNA (siRNA) on the biological behavior of the LoVo human colorectal carcinoma cell line and to provide evidence for the feasibility of colorectal cancer gene therapy. LoVo cells were divided into the RIP1 siRNA group, the blank c...

    journal_title:Oncology letters

    pub_type: 杂志文章

    doi:10.3892/ol.2014.2040

    authors: You HX,Zhou YH,Tan SY,She TH

    更新日期:2014-06-01 00:00:00

  • STMN1 accumulation is associated with dysplastic and neoplastic lesions in patients with ulcerative colitis.

    abstract::Ulcerative colitis (UC) is thought to be associated with precancerous lesions that can ultimately lead to colon cancer. Therefore, diagnostic markers for colorectal dysplasia and cancer are urgently needed for patients with UC. Stathmin 1 (STMN1) is a novel cancer biomarker that is also a novel target for treatment in...

    journal_title:Oncology letters

    pub_type: 杂志文章

    doi:10.3892/ol.2019.10814

    authors: Osone K,Yokobori T,Katayama C,Takahashi R,Kato R,Tatsuski H,Takada T,Yajima R,Motegi Y,Ogawa H,Fujii T,Ojima H,Nakamura J,Yao T,Shirabe K,Kuwano H

    更新日期:2019-11-01 00:00:00

  • Correlation between FOXP3 expression and gastric cancer.

    abstract::The aim of the present study was to investigate the expression and function of forkhead box protein 3 (FOXP3) in gastric cancer using a rat model. A total of 92 Wistar rats were divided into two groups: An experimental group (n=46) and a control group (n=46). In the experimental group, sarcosine ethyl ester hydrochlor...

    journal_title:Oncology letters

    pub_type: 杂志文章

    doi:10.3892/ol.2016.4752

    authors: Guo G,He Z,Shi Z

    更新日期:2016-08-01 00:00:00

  • Malignant neoplasia arising from ovarian remnants following bilateral salpingo-oophorectomy (Review).

    abstract::Ovarian remnant syndrome (ORS) is a rare, but well-known gynecological complication, most often induced by difficult bilateral salpingo-oophorectomy (BSO) procedures that leave residual ovarian tissue on the pelvic wall. The most common preexisting conditions for this complication include endometriosis, pelvic inflamm...

    journal_title:Oncology letters

    pub_type: 杂志文章

    doi:10.3892/ol.2014.2089

    authors: Imai A,Matsunami K,Takagi H,Ichigo S

    更新日期:2014-07-01 00:00:00

  • Giant cell tumor of bone arising in long bones possibly originates from the metaphyseal region.

    abstract::Giant cell tumor of bone (GCTB) is a primary benign bone tumor with a locally aggressive character. Definitive descriptions of the site of origin for this type of tumor are not available. The aim of the present study was to evaluate the site of origin of GCTB of long bones with regards to epiphyseal lines by means of ...

    journal_title:Oncology letters

    pub_type: 杂志文章

    doi:10.3892/ol.2016.4264

    authors: Futamura N,Urakawa H,Tsukushi S,Arai E,Kozawa E,Ishiguro N,Nishida Y

    更新日期:2016-04-01 00:00:00

  • Serum peptidomic profiling identifies a minimal residual disease detection and prognostic biomarker for patients with acute leukemia.

    abstract::The evaluation of minimal residual disease (MRD) in acute leukemia (AL) is currently recognized as a potential critical tool to assess the response and relapse rate of treatments. The present study investigated serum peptides from patients with AL to identify biomarkers that would be useful in providing clinical evalu...

    journal_title:Oncology letters

    pub_type: 杂志文章

    doi:10.3892/ol.2013.1574

    authors: Song W,Wang N,Li W,Wang G,Hu J,He K,Li Y,Meng Y,Chen N,Wang S,Hu L,Xu B,Wang J,Li A,Cui J

    更新日期:2013-11-01 00:00:00

  • Role of podocalyxin in astrocytoma: Clinicopathological and in vitro evidence.

    abstract::The present study examined the expression of podocalyxin (PODX) in surgically-resected astrocytomas, associated the levels of PODX expression with the clinicopathological characteristics and survival outcomes of astrocytoma and assessed how PODX affected the viability of astrocytoma cells following the administration ...

    journal_title:Oncology letters

    pub_type: 杂志文章

    doi:10.3892/ol.2013.1556

    authors: Huang T,Jin X,He L,Zhang M,Wu J,Wang Y,Fang J

    更新日期:2013-11-01 00:00:00