MicroRNA and endometrial cancer: Roles of small RNAs in human tumors and clinical applications (Review).

abstract：:Prognosis and treatment differences between initial and second primary chondrosarcoma (pCS) remain unknown. In the present study, patients with chondrosarcoma diagnosed between January 2004 and December 2015 were identified using the Surveillance Epidemiology and End Results database. Kaplan-Meier curves and log-rank ...

journal_title：Oncology letters

authors： Mao W,Kong M,Yu H,Wang D,Huang X,Yao X,Fan J,Geng J

更新日期：2019-07-01 00:00:00

abstract：:The present study reports a case of low-grade fibromyxoid sarcoma that occurred in a 62-year-old woman 9 years subsequent to whole breast irradiation for a carcinoma of the left breast, and 18 years following chemotherapy and radiotherapy (RT) for non-Hodgkin's lymphoma (NHL; diagnosed at the age of 43). The patient w...

journal_title：Oncology letters

authors： Shibata S,Shiraishi K,Yamashita H,Kobayashi R,Nakagawa K

更新日期：2016-04-01 00:00:00

abstract：:Emerging evidence has revealed that mitochondrial DNA (mtDNA) is encapsulated in plasma extracellular vesicles (EVs). However, the characteristics of mtDNA in EVs from patients with cancer remain largely unexplored, which greatly limits its clinical application. Whole genome and capture-based sequencing found that EV ...

journal_title：Oncology letters

authors： Li Y,Guo X,Guo S,Wang Y,Chen L,Liu Y,Jia M,An J,Tao K,Xing J

更新日期：2020-09-01 00:00:00

abstract：:The issue of delayed neurological damage as a result of treatment is becoming increasingly important now that an increased number of children survive treatment for acute lymphoblastic leukemia (ALL). Following modification of the treatment protocols, severe symptomatic late effects are rare, and most adverse effects a...

journal_title：Oncology letters

authors： Badr MA,Hassan TH,El-Gerby KM,Lamey ME

更新日期：2013-02-01 00:00:00

abstract：:Prostate cancer is the most common form of cancer in men, with increased incidence rates observed in older individuals. Prostate cancer is primarily driven via activation of the androgen receptor (AR), the principal transcriptional factor governing prostate cancer cellular programming and its associated metabolism. On...

journal_title：Oncology letters

authors： Dan C,Zhang H,Zeng W,Huang L,Gong X,Li H,Yang E,Wang L,Yao Q

更新日期：2019-01-01 00:00:00

abstract：:DNA hypomethylation is associated with carcinogenesis due to its involvement in cancer initiation and progression. In this study we analyzed the hypomethylation status of candidate genes in clear cell renal cell carcinoma (CCRCC) using a large-scale, high-throughput DNA methylation profiling technique. Results reveale...

journal_title：Oncology letters

authors： Yoo KH,Park YK,Chang SG

更新日期：2013-01-01 00:00:00

abstract：:Previous studies have revealed the aberrant expression of a number of microRNAs (miRNA/miRs) in the blood circulation of patients with breast cancer (BC). The aim of the present study was to assess the effect of neoadjuvant chemotherapy on the levels of a panel of BC-associated miRNAs, which are at relatively low (let...

journal_title：Oncology letters

authors： Gezer U,Keskin S,Iğci A,Tükenmez M,Tiryakioğlu D,Cetinkaya M,Dişci R,Dalay N,Eralp Y

更新日期：2014-08-01 00:00:00

abstract：:The present study examined the expression of podocalyxin (PODX) in surgically-resected astrocytomas, associated the levels of PODX expression with the clinicopathological characteristics and survival outcomes of astrocytoma and assessed how PODX affected the viability of astrocytoma cells following the administration ...

journal_title：Oncology letters

authors： Huang T,Jin X,He L,Zhang M,Wu J,Wang Y,Fang J

更新日期：2013-11-01 00:00:00

abstract：:Breast cancer has a major impact on the health of women worldwide. In the Kingdom of Saudi Arabia (KSA), breast cancer incidence is on the increase and is characterized by early onset and aggressiveness. Owing to the importance of the TP53 gene in breast carcinogenesis, we analyzed the possible link between TP53 singl...

journal_title：Oncology letters

authors： Al-Qasem A,Toulimat M,Tulbah A,Elkum N,Al-Tweigeri T,Aboussekhra A

更新日期：2012-04-01 00:00:00

abstract：:Primary Ewing's sarcoma (ES) is rare, especially when it occurs in the spinal canal during middle or old age. The rarity of Ewing's sarcoma breakpoint region 1 fusion-negative ES has been reported in the literature. The present case report describes a 60-year-old Chinese patient who was diagnosed with ES originating f...

journal_title：Oncology letters

authors： Yan D,Zhang J,Zhong D

更新日期：2019-12-01 00:00:00

abstract：:Sarcomas arise from primitive mesenchymal cells, which are classified, into two main groups: Bone and soft tissue sarcomas. We have searched all-important electronic databases including Google scholar and PubMed for the collection of latest literature pertaining to pediatric sarcomas. Latest literature confirmed that ...

journal_title：Oncology letters

authors： Cao J,An Q,Wang L

更新日期：2018-02-01 00:00:00

abstract：:Aldo-keto reductases, known as AKR1C1-AKR1C4 enzymes, are pivotal to NADPH-dependent reduction, and their expression is highly associated with the progression of malignant cancers. However, the expression and distinct prognostic value of the AKR1C family members in liver cancer are not well established. In the current...

journal_title：Oncology letters

authors： Zhao SF,Wang SG,Zhao ZY,Li WL

更新日期：2019-11-01 00:00:00

abstract：:[This retracts the article DOI: 10.3892/ol.2016.4607.]. ...

journal_title：Oncology letters

authors： Li L,Mao X,Qin X,Zhou M,Xing H,Dong F,Jiang X,Zhuang W

更新日期：2019-05-01 00:00:00

abstract：:Glycocholic acid (GCA) is a novel identified biomarker for hepatocellular carcinoma (HCC). However, clinical pathological study of GCA has not been extensive due to the limited availability of anti-GCA monoclonal antibodies (mAbs) and restricted detection methods. In the present study, using human GCA conjugated with ...

journal_title：Oncology letters

authors： Wu M,Zhai S,Gao J,Wei D,Xue J,Zhou Y,Li N,Hu L

更新日期：2019-03-01 00:00:00

abstract：:This study aimed to investigate the clinicopathological characteristics, differential diagnosis and prognosis of pulmonary epithelioid hemangioendothelioma (PEH). PEH is a rare low-grade malignant vascular tumor. The cause of PEH remains unclear. Patient prognosis is unpredictable, with life expectancy ranging from 1 ...

journal_title：Oncology letters

authors： Shao J,Zhang J

更新日期：2014-12-01 00:00:00

abstract：:MicroRNA-181 (miR-181) has been recently demonstrated to participate in the differentiation and development of immune cells, including natural killer cells and B and T lymphocytes, and myeloid linages, including erythroid and megakaryocytic cells. The aberrant expression of miR-181, particularly low expression levels,...

journal_title：Oncology letters

authors： Wang G,Zhao R,Zhao X,Chen XI,Wang D,Jin Y,Liu XI,Zhao CI,Zhu Y,Ren C,Li M,Jin X,Zhang F,Zhong Z,Wang T,Li X

更新日期：2015-11-01 00:00:00

abstract：:The incidence of gastric cancer is high, especially in China. The present study aims to provide a novel therapeutic target for gastric cancer. Peripheral blood, cancerous and paracancerous tissues were collected from patients with gastric cancer. T-cell immunoglobulin mucin domain-3 (Tim-3) expression in T-cells was m...

journal_title：Oncology letters

authors： Yu J,Zhang H,Sun S,Sun S,Li L

更新日期：2019-02-01 00:00:00

abstract：:Carbohydrate antigen 19-9 (CA19-9) is not generally considered to be a biomarker in pancreatic neuroendocrine tumors (pNETs), as the majority of pNETs present with a normal range of CA19-9. The present study aimed to evaluate the role of serum CA19-9 levels as a prognostic factor in a relatively large number of patien...

journal_title：Oncology letters

authors： Luo G,Jin K,Cheng H,Liu C,Guo M,Lu Y,Yang C,Xu J,Wang W,Gao H,Zhang S,Long J,Xu J,Ni Q,Chen J,Yu X

更新日期：2017-12-01 00:00:00

abstract：:The present study aimed to explore the clinical efficacy and safety of hydromorphone combined with sufentanil in patient-controlled intravenous analgesia (PCIA) for patients with hepatocellular carcinoma (HCC) and its effect on serum immune factors in serum. Data from 385 patients with HCC, admitted to the Hunan Provi...

journal_title：Oncology letters

authors： Liu J,Wang Y,Tang Y,Luo J,Long Y,Tan S

更新日期：2020-12-01 00:00:00

abstract：:Cyclin-dependent kinase inhibitor 2A (p16INK4a) protein is a surrogate immunohistochemical marker of human papillomavirus infection in oropharynx squamous cell carcinoma (OPSCC). However, the effects of p16INK4a in non-OPSCC require additional analysis. In addition, major gaps remain in the literature, including small...

journal_title：Oncology letters

authors： Yang H,Cao Y,Li ZM,Li YJ,Jiang WQ,Shi YX

更新日期：2018-11-01 00:00:00

abstract：:Pancreatic cancer is one of the most frequently occurring malignancies worldwide and it is the fourth most common cause of cancer-associated mortality in Western countries. Thalidomide (THD) plays an important role in tumor therapy, as it is able to promote early stage apoptosis and inhibit the process of angiogenesis...

journal_title：Oncology letters

authors： Qiao Z,Yuan J,Shen J,Wang C,He Z,Hu Y,Zhang M,Xu C

更新日期：2015-05-01 00:00:00

abstract：:Inhibition of nuclear factor-κB (NF-κB) results in antitumor activity in leukemia cells, and may be a potential therapeutic strategy for the treatment of leukemia. However, a significant limitation of NF-κB inhibition in the treatment of leukemia is the low efficiency of this technique. NF-κB inhibitor treatment induc...

journal_title：Oncology letters

authors： Dong QM,Ling C,Chen X,Zhao LI

更新日期：2015-12-01 00:00:00

abstract：:Intramuscular myxoma (IM) is a benign intramuscular neoplasm composed of fibroblasts and abundant myxoid stroma. IMs most commonly affect larger skeletal muscles, while those affecting the oral and maxillofacial regions are rare, with a small number of documented cases in the available literature. The aim of the prese...

journal_title：Oncology letters

authors： Li G,Jiang W,Li W,Li J

更新日期：2014-05-01 00:00:00

abstract：:KRAS mutation is frequently identified in advanced colorectal carcinoma (CRC); however, its prognostic significance and the associated histological features have remained to be clarified. In the present study, the precise histological results and prognostic value of KRAS-mutated CRCs were investigated in patients from...

journal_title：Oncology letters

authors： Lee HS,Hwang DY,Han HS

更新日期：2020-07-01 00:00:00

abstract：:Elongator protein 3 (ELP3), the catalytic subunit of the elongator complex of RNA polymerase II, is involved in various functions, including transcriptional elongation, chromatin modification and cytoskeletal regulation. In this study, ELP3 expression was immunohistochemically examined in normal uterus tissue and uter...

journal_title：Oncology letters

authors： Wang Y,Ikeda JI,Rahadiani N,Mamat S,Ueda Y,Tian T,Enomoto T,Kimura T,Aozasa K,Morii E

更新日期：2012-01-01 00:00:00

abstract：:As a rare hypopharyngeal diverticulum, Killian-Jamieson diverticulum (KJD) is usually incidentally detected, small, asymptomatic and likely to be misdiagnosed as a thyroid nodule. In order to avoid unnecessary treatments resulting from misdiagnosis, principles to distinguish between esophageal diverticula and thyroid ...

journal_title：Oncology letters

authors： Cao L,Ge J,Zhao D,Lei S

更新日期：2016-10-01 00:00:00

abstract：:Collecting duct carcinoma (CDC) is a rare type of renal neoplasm. Early diagnosis is possibly the only factor leading to a prolonged survival for patients with CDC. The purpose of the present study was to characterize the imaging features of CDC and improve its diagnosis. Radiological data of six patients were retrosp...

journal_title：Oncology letters

authors： Hu Y,Lu GM,Li K,Zhang LJ,Zhu H

更新日期：2014-02-01 00:00:00

abstract：:Fibroadenomas are a type of benign tumor that occur in young women below the age of 35 years old. The tumors are the second most common type of tumor after fibrocystic disease. The chance of carcinoma arising in a fibroadenoma is extremely low. To date, <130 such cases have been reported. Previous studies have reporte...

journal_title：Oncology letters

authors： Zheng H,Chen J,Wu X,Jin L,Qi C

更新日期：2015-09-01 00:00:00

abstract：:The present case report describes the infrequent coexistence of squamous cell transformation and the epidermal growth factor receptor (EGFR) T790M mutation as resistance mechanisms to first line treatment with tyrosine kinase inhibitors. The patient was a 44-year-old female, diagnosed with a primitive advanced lung ad...

journal_title：Oncology letters

authors： Bruno R,Proietti A,Alì G,Puppo G,Ribechini A,Chella A,Fontanini G

更新日期：2017-11-01 00:00:00

abstract：:The aim of the present study was to assess the expression of microRNA-146a (miR-146a) in human lung adenocarcinoma cells, its effect on cellular behaviors, and the underlying molecular mechanisms. Reverse transcription-quantitative PCR (RT-qPCR) was used to measure miR-146a expression in the human normal lung epitheli...

journal_title：Oncology letters

authors： Yuan F,Zhang S,Xie W,Yang S,Lin T,Chen X

更新日期：2020-06-01 00:00:00