Intramuscular myxoma of the hyoglossus muscle: A case report and literature review.

abstract：:Solitary fibrous tumors (SFTs) are uncommon, with the pleura as a site of predilection. Central nervous system SFTs, particularly intracranial SFTs, are extremely rare. The lesions are generally benign and localized, and surgery is the main therapeutic solution. The current study reports the cases of a patient who pre...

journal_title：Oncology letters

authors： Wang ZY,Qiu K,Ma YH,Wang XT,Bao JJ,Zhang ZF,Liu XZ

更新日期：2016-02-01 00:00:00

abstract：:The prognosis following surgical treatment of gastric carcinoma (GC) or gastroesophageal junction (GEJ) adenocarcinoma remains poor. Although adjuvant chemo-radiotherapy with 5-fluorouracil has been shown to be beneficial, a high rate of distant failure has been reported. Thus, the toxicity profile and efficacy of an ...

journal_title：Oncology letters

authors： Shulman K,Haim N,Wollner M,Bernstein Z,Abdah-Bortnyak R,Bar-Sela G

更新日期：2012-05-01 00:00:00

abstract：:Lung cancer is one of the most common cancers, which is the leading cause of cancer-related death among various cancers worldwide. Flavokawain A (FKA), a chalcone found in the kava plant, exerts potent anticancer activity. However, the activity and mechanisms of FKA in inhibiting the viability of paclitaxel (PTX)-resi...

journal_title：Oncology letters

authors： Li J,Zheng L,Yan M,Wu J,Liu Y,Tian X,Jiang W,Zhang L,Wang R

更新日期：2020-01-01 00:00:00

abstract：:Hypoxic microenvironments and angiogenesis have been a focus of tumor research in previous years. The aim of the the present study was to create a hypoxic model and observe the effect of hypoxia on the expression of hypoxia inducible factor-1α (HIF-1α), insulin-like growth factor I (IGF-1) and vascular endothelial gro...

journal_title：Oncology letters

authors： Liu Q,Xu Z,Mao S,Chen W,Zeng R,Zhou S,Liu J

更新日期：2015-03-01 00:00:00

abstract：:The collagen gel droplet embedded culture-drug sensitivity test (CD-DST) is an anticancer drug sensitivity test developed about 10 years ago. This study reports the application of this test in the choice of neoadjuvant chemotherapy for the treatment of one patient with a large synovial sarcoma in the right shank. A 28...

journal_title：Oncology letters

authors： Gu F,Ma Y,Fan Y,Lang R,Ding T,Hao X,Gong Y,Kobayahsi H,Fang Z,Fu L

更新日期：2010-09-01 00:00:00

abstract：:Primary mediastinal extraskeletal Ewing's sarcoma (EES) is quite rare. To the best of our knowledge, only five cases have been reported. Given the paucity of data, there is consequently no optimal treatment strategy available. The current study presents the case of a 51-year-old female with unresectable EES of the pos...

journal_title：Oncology letters

authors： Liu M,Liu B,Dong L,Han T,Zhang L

更新日期：2015-02-01 00:00:00

abstract：:Decoy receptor 3 (DcR3) is a tumor necrosis factor receptor, which may inhibit apoptosis. The aim of the present study was to investigate the clinical significance of DcR3 upregulation in patients with chronic hepatitis B (CHB) and hepatic fibrosis. A total of 128 patients with a clinical diagnosis of CHB who underwen...

journal_title：Oncology letters

authors： Lou X,Hou Y,Cao H,Zhao J,Zhu F

更新日期：2018-07-01 00:00:00

abstract：:The present study reported three rare cases of multicystic vestibular schwannoma with fluid-fluid levels. These three tumors exhibited apparent fluid-fluid levels that demonstrated a radiological appearance of two fluid levels in the cystic area. Two cases had an acute history, whereas one case presented with a chroni...

journal_title：Oncology letters

authors： Li P,Bi Z,Hao S,Zhang J

更新日期：2015-07-01 00:00:00

abstract：:Ovarian cancer is the most malignant gynecologic neoplasm in women and has the worst prognosis of all cancer types in women based on the 5-year survival rates. A previous study indicated that mangiferin exerts an anti-neoplastic effect on human ovarian cancer cells by targeting Notch3. Additionally, it has been demons...

journal_title：Oncology letters

authors： He W,You Y,Du S,Lei T,Wang H,Li X,He X,Tong R,Wang Y

更新日期：2019-01-01 00:00:00

abstract：:The current study presents the case of a 68-year-old female patient who received biological intensity-modulated radiotherapy (BIMRT) and neoadjuvant chemotherapy for multiple peritoneal metastases of ovarian cancer. The International Federation of Gynecology and Obstetrics disease stage was IIIc. In addition, the pati...

journal_title：Oncology letters

authors： Huang S,Dang Y,Li F,Wei W,Ma Y,Qiao S,Wang Q

更新日期：2015-03-01 00:00:00

abstract：:The frequency of deficient mismatch repair (dMMR) or microsatellite instability-high colorectal cancer (CRC) is estimated to be ~15% of all patients with CRC; however, the patients reported are limited to surgical cases, and the frequency of patients exhibiting stage 0 disease is not considered, despite the currently ...

journal_title：Oncology letters

authors： Sugiyama T,Iwaizumi M,Kaneko M,Tani S,Yamade M,Hamaya Y,Furuta T,Miyajima H,Osawa S,Baba S,Maekawa M,Sugimoto K

更新日期：2020-09-01 00:00:00

abstract：:Breast tissue is very sensitive to ionizing radiation due to the presence of reproductive hormones, including estrogen. In the present pilot study, the efficiency of mammography X-rays to induce DNA double strand breaks (DSB) in mammary epithelial cells was investigated. For this, freshly resected healthy breast tissu...

journal_title：Oncology letters

authors： Depuydt J,Viaene T,Blondeel P,Roche N,Van den Broecke R,Thierens H,Vral A

更新日期：2018-09-01 00:00:00

abstract：:Skeletal muscle is rich in lymphatic vessels, with an abundant blood supply, and it is an infrequent site of cancer metastasis. Previous studies have demonstrated that enhanced secretion of MyoD may occur when skeletal muscle is injured or becomes cancerous. It was hypothesized that MyoD may act as an endogenous cytok...

journal_title：Oncology letters

authors： Cai C,Qin X,Wu Z,Shen Q,Yang W,Zhang S,Duan J,Liang F,Liu C

更新日期：2016-06-01 00:00:00

abstract：:Epithelial-mesenchymal transition (EMT) is a process by which cancer cells acquire mesenchymal properties, such as induction of vimentin, while epithelial-associated genes like E-cadherin are lost. This enables cells to be more metastatic. Factors that are able to induce EMT include growth factors such as transforming...

journal_title：Oncology letters

authors： Randle DD,Clarke S,Henderson V,Odero-Marah VA

更新日期：2013-12-01 00:00:00

abstract：:A gallbladder neuroendocrine neoplasm (GB-NEN) is a unique heterogeneous neoplasm, originating from neuroendocrine cells and able to secrete peptides as its neurotransmitter. Among all the neuroendocrine tumors (NETs), the GB-NEN prevalence is 0.5%, which accounts for ~2.1% of all gallbladder tumors. The current study...

journal_title：Oncology letters

authors： Niu C,Wang S,Guan Q,Ren X,Ji B,Liu Y

更新日期：2020-05-01 00:00:00

abstract：:Laryngeal squamous cell carcinoma (LSCC) is a genetically complex tumor type and one of the leading causes of cancer-associated disability and mortality. Genetic instability, such as chromosomal instability, is associated with the tumorigenesis of LSCC. Copy number variations (CNVs) have been demonstrated to contribut...

journal_title：Oncology letters

authors： Li D,Wang X,Lu S,Wang P,Wang X,Yin W,Zhu W,Li S

更新日期：2020-08-01 00:00:00

abstract：:Death associated protein kinase 1 (DAPK1) is a notable serine/threonine kinase involved in the regulation of multiple cellular pathways, including apoptosis and autophagy. Although DAPK1 is usually considered to be a tumor suppressor, it was previously reported to promote the viability of p53 mutant cancer cell lines ...

journal_title：Oncology letters

authors： Huang Y,Lin M,Chen X,Huang C,Zhang X,Chen L,Wu K,Chen Y,Zhu Y,Lin Y

更新日期：2018-06-01 00:00:00

abstract：:Papillary thyroid cancer (PTC) is the most common type of thyroid malignancy, and it is often observed to overexpress epidermal growth factor receptor (EGFR). Previous research has indicated that EH domain-containing 1 (EHD1) is associated with EGFR-mediated endocytotic recycling in multiple tumor types. The objective...

journal_title：Oncology letters

authors： Liu Y,Liang Y,Li M,Liu D,Tang J,Yang W,Tong D,Jin X

更新日期：2018-10-01 00:00:00

abstract：:Pulmonary sequestration (PS) is an uncommon lung disease. Carcinoid tumorlets in pulmonary sequestration are extremely rare. This case report presents a rare clinical case of carcinoid tumorlet in pulmonary sequestration with bronchiectasis after breast cancer. A 64-year-old female was diagnosed with infiltrating duct...

journal_title：Oncology letters

authors： Ye Y,Mu Z,Wu D,Xie Y

更新日期：2013-05-01 00:00:00

abstract：:The purpose of the present study was to investigate the clinical significance of BRCA1/BRCA2 DNA repair associated (BRCA1/BRCA2) gene expression in patients with sporadic gastric cancer (GC) who had received postoperative adjuvant chemotherapy. Breast cancer type 1 and 2 susceptibility protein (BRCA1 and BRCA2) expres...

journal_title：Oncology letters

authors： Kim HS,Hwang IG,Min HY,Bang YJ,Kim WH

更新日期：2019-05-01 00:00:00

abstract：:The transcription factor forkhead box O1 (FOXO1) can be inactivated via its phosphorylation, resulting in suppression of apoptosis. Using immunohistochemistry, the expression of a phosphorylated form of FOXO1 was assessed in upper urinary tract urothelial carcinoma (UUTUC) specimens. Overall, phospho-FOXO1 (p-FOXO1) w...

journal_title：Oncology letters

authors： Ide H,Jiang G,Mizushima T,Fujita K,Inoue S,Yamaguchi S,Fushimi H,Nonomura N,Miyamoto H

更新日期：2019-01-01 00:00:00

abstract：:Activation of the hepatocyte growth factor (HGF)/c-Met signaling pathway was identified to be associated with malignant tumors. The present study aimed at determining the expression of HGF and c-Met in gastric carcinogenesis and its association with Helicobacter pylori infection. Gastric biopsies were obtained from 16...

journal_title：Oncology letters

authors： Xie C,Yang Z,Hu Y,Cao X,Chen J,Zhu Y,Lu N

更新日期：2017-11-01 00:00:00

abstract：:The present study aimed to investigate the impact of overexpression of long noncoding RNA PEG10 (lncRNA PEG10) on the proliferation, invasion and metastasis of hypopharyngeal squamous cell carcinoma (HSCC). Quantitative reverse transcription polymerase chain reaction was used to quantify lncRNA PEG10 expression levels...

journal_title：Oncology letters

authors： Zhao M,Sun D,Li X,Xu Y,Zhang H,Qin Y,Xia M

更新日期：2017-09-01 00:00:00

abstract：:Liver cancer is the sixth most commonly occurring cancer globally, and the main histological type is hepatocellular carcinoma. This type of neoplasia has a poor prognosis due to a high rate of recurrence and intrahepatic metastasis, which are closely are closely associated with the angiogenic process. Vascular endothe...

journal_title：Oncology letters

authors： Colombo J,Maciel JM,Ferreira LC,DA Silva RF,Zuccari DA

更新日期：2016-07-01 00:00:00

abstract：:Numerous studies have shown that marital status may be a prognostic factor in various malignancies, but little is known about its effect on duodenal adenocarcinoma. The aim of the present study was to determine the association between marital status and survival in patients with duodenal adenocarcinoma. The Surveillan...

journal_title：Oncology letters

authors： Wang N,Bu Q,Liu Q,Yang J,He H,Liu J,Ren X,Lyu J

更新日期：2019-08-01 00:00:00

abstract：:Krüppel-like factor 5 (KLF5) is frequently deleted and inactivated in prostate cancer, and exerts tumor-suppressing function in prostate cancer cells. However, the function of KLF5 in the apoptosis of prostate cancer cells remains unclear. In the present study, the effect of KLF5 on phorbol 12-myristate 13-acetate (PM...

journal_title：Oncology letters

authors： Shi Q,Jia J,Hui K,Gao Y,Xu S,Guan B,Tang X,Wang X,He D,Guo P

更新日期：2017-08-01 00:00:00

abstract：:Gelatinases are overexpressed in several types of maligancies and tumor stromal cells. Lidamycin is an enediyne antitumor antibiotic, which is composed of an apoprotein (LDP) and an active chromophore (AE). It is known that the heavy-chain complementarity-determining region-3 (CDR3) domain of scFv is important in anti...

journal_title：Oncology letters

authors： Zhong GS,Wu MN,Guo XF,Xu ZS,Zhang SH,Zhen YS

更新日期：2013-04-01 00:00:00

abstract：:CD133+ tumor cells have a greater potential ability for tumorigenesis, proliferation, invasion and metastasis compared with CD133- tumor cells. Ki-67 is associated with cell proliferation in various tumors and has a markedly positive correlation with the prognosis of patients. However, there are a limited number of st...

journal_title：Oncology letters

authors： Lu C,Liu L,Wu X,Xu W

更新日期：2013-11-01 00:00:00

abstract：:Dendritic cell-specific intercellular adhesion molecule-3-grabbing nonintegrin-related protein (DC-SIGNR) is a type II transmembrane protein that has been reported to bind to various pathogens and participate in immunoregulation and tumorigenesis. However, further research is required to investigate whether the level ...

journal_title：Oncology letters

authors： Wang X,Jiang Y,Yuan M,Chen C,Wang K,Zhang Q,Zuo Y,Ren S

更新日期：2017-09-01 00:00:00

abstract：:Salidroside is one of the most potent compounds extracted from the plant Rhodiola rosea, and its cardiovascular protective effects have been studied extensively. However, the role of salidroside in human ovarian carcinoma remains unknown. The aim of the current study was to investigate the effects of salidroside on th...

journal_title：Oncology letters

authors： Yu G,Li N,Zhao Y,Wang W,Feng XL

更新日期：2018-05-01 00:00:00