Role of podocalyxin in astrocytoma: Clinicopathological and in vitro evidence.

abstract：:Bufalin, one of the active ingredients of the Chinese drug Chan su, exhibits significant antitumor activity against various cancer types. However, the role of bufalin in renal cell carcinoma (RCC) remains unclear. In the present study, it was demonstrated that bufalin inhibited cell proliferation, blocked the cell cyc...

journal_title：Oncology letters

authors： Xie J,Lin W,Huang L,Xu N,Xu A,Chen B,Watanabe M,Liu C,Huang P

更新日期：2018-09-01 00:00:00

abstract：:A number of available studies have focused on the role of mastocytes and their angiogenic factors, such as tryptase expression, in cancer growth as a major research objective. Cardiac myxoma is a rare neoplasia and is the most common primary tumor of the heart. The cellular elements of cardiac myxoma have an endotheli...

journal_title：Oncology letters

authors： Donato G,Conforti F,Camastra C,Ammendola M,Donato A,Renzulli A

更新日期：2014-07-01 00:00:00

abstract：:The current study aimed to explore whether the efficiency of the standard International Prognostic Index (S-IPI), revised-IPI (R-IPI) and enhanced-IPI (NCCN-IPI) in evaluating the prognosis of patients with diffuse large B-cell lymphoma (DLBCL) may be improved by interim 18F-FDG PET/CT. A total of 185 patients with ne...

journal_title：Oncology letters

authors： Jiang M,Chen P,Ruan X,Ye X,Pan Y,Zhang J,Huang Q,Zhou W,Wu H,Wang Q

更新日期：2017-12-01 00:00:00

abstract：:Docetaxel is the current first-line treatment for castration-resistant prostate cancer (CRPC), following failure to respond to maximal androgen blockade (MAB). Patients who fail to respond to docetaxel may receive cabazitaxel or abiraterone; however, there are no recommendations on which of these two agents should be ...

journal_title：Oncology letters

authors： Marech I,Vacca A,Sivestris N,Gnoni A,Lorusso V

更新日期：2013-06-01 00:00:00

abstract：:The present study aimed to identify microRNA (miRNA) expression profiles associated with brain metastases of colorectal cancers. We conducted miRNA expression profiling of 3 primary colorectal cancers and 3 brain-metastatic carcinomas using Agilent Human miRNA Microarrays. Quantitative real-time reverse transcription-...

journal_title：Oncology letters

authors： Li Z,Gu X,Fang Y,Xiang J,Chen Z

更新日期：2012-02-01 00:00:00

abstract：:The present study aims to investigate the radiosensitization effect of the migration and invasion inhibitory protein (MIIP) gene on nasopharyngeal carcinoma (NPC) cells. The MIIP gene was transfected into NPC 5-8F and CNE2 cells. The level of MIIP was analyzed by quantitative reverse transcription-polymerase chain rea...

journal_title：Oncology letters

authors： Zhou HP,Qian LX,Zhang N,Gu JJ,Ding K,Wu J,Lu ZW,Du MY,Zhu HM,Wu JZ,He X,Yin L

更新日期：2018-06-01 00:00:00

abstract：:Pancreatic cancer is a deadly disease that is frequently associated with mortality at the time of diagnosis due to rapid metastasis, which makes it unsuitable for operative surgery, and resistant to chemotherapy and radiation therapy. Isochorismatase domain-containing protein 1 (ISOC1) has putative isochorismatase act...

journal_title：Oncology letters

authors： Cheng L,Zhao Y,Tang M,Luo Z,Wang X

更新日期：2019-05-01 00:00:00

abstract：:The aim of the present study was to determine the usefulness of the positron emission tomography/computed tomography (PET/CT) with 18F-fluorodeoxyglucose (FDG) in the detection of recurrence or metastasization of differentiated thyroid carcinoma (DTC) in patients with abnormal thyroglobulin levels and negative finding...

journal_title：Oncology letters

authors： Lu CZ,Cao SS,Wang W,Liu J,Fu N,Lu F

更新日期：2016-04-01 00:00:00

abstract：:For osteoblastoma, with its predilection for the spinal column and appendicular skeleton, the skull is an unusual site, and paranasal sinus involvement is very rare. Herein, we report on a case in which the disease was located within the sphenoid bone. To the best of our knowledge, this is the 4th reported case of ost...

journal_title：Oncology letters

authors： Kukwa W,Oziębło A,Oecińska A,Czarnecka AM,Włodarski K,Kukwa A

更新日期：2010-03-01 00:00:00

abstract：:Osteosarcoma (OS) is the most common form of bone malignancy in children and adolescents. A class of molecules known as microRNAs (miRNAs) have been routinely associated in the development and progression of OS. The present study was centered on the less well-known miRNA, miRNA (miR)-150, and its role in OS was invest...

journal_title：Oncology letters

authors： Li CH,Yu TB,Qiu HW,Zhao X,Zhou CL,Qi C

更新日期：2017-04-01 00:00:00

abstract：:The aim of the present study was to investigate the relationship between the expression of transcription factor forkhead box C2 (FOXC2) and the clinical features of cervical cancer. A total of 66 patients with cervical cancer, 42 patients with cervical intraepithelial neoplasia (CIN) and 25 patients with cervical infl...

journal_title：Oncology letters

authors： Wang J,Yue X

更新日期：2017-12-01 00:00:00

abstract：:Interleukin (IL)-37, a new IL-1 family member, has received increasing attention in recent years. In the past decade, it has been determined that IL-37 is expressed in various normal cells and tissues and is regulated by inflammatory stimuli and pro-cytokines via different signal transduction pathways. Recently, it ha...

journal_title：Oncology letters

authors： Wang L,Quan Y,Yue Y,Heng X,Che F

更新日期：2018-04-01 00:00:00

abstract：:The aim of the present study was to obtain comprehensive microRNA (miRNA) profiles of type I [Ishikawa (ISK)] and type II (HEC-1B) human endometrial adenocarcinoma cell lines, utilizing the latest high-throughput sequencing techniques. RNA was extracted from ISK and HEC-1B cell lines. Sequencing results were obtained ...

journal_title：Oncology letters

authors： Lu J,Zhang X,Zhang R,Ge Q

更新日期：2015-12-01 00:00:00

abstract：:Ovarian cancer (OVAC) remains the most lethal gynecological malignancy; it is ranked fifth among the most common types of cancer that affect women worldwide. Several aspects of the disease, including molecular pathogenesis, epidemiology, histological subtypes, poor prognosis at early stages due to the absence of speci...

journal_title：Oncology letters

authors： Sun W,Fu S

更新日期：2019-09-01 00:00:00

abstract：:This study aimed to investigate the clinicopathological characteristics, differential diagnosis and prognosis of pulmonary epithelioid hemangioendothelioma (PEH). PEH is a rare low-grade malignant vascular tumor. The cause of PEH remains unclear. Patient prognosis is unpredictable, with life expectancy ranging from 1 ...

journal_title：Oncology letters

authors： Shao J,Zhang J

更新日期：2014-12-01 00:00:00

abstract：:Although ring finger protein 2 (RNF2) serves an important role in the occurrence, development and regulation of various types of cancer, RNF2 expression in skin squamous cell carcinoma (SCC) remains unknown. The aim of the present study was to investigate the role of RNF2 expression in SCC and adjacent tissues from pa...

journal_title：Oncology letters

authors： Ling B,Yao M,Li G,Liu J,Liu B,Wang W,Jiang B

更新日期：2020-08-01 00:00:00

abstract：:Endometrial cancer (EC) is the most commonly diagnosed gynecological malignancy in Australian women. Notably, its incidence and mortality rate is increasing. Despite this, there are limited treatment options for EC. Galectin-7 regulates tumorigenesis in numerous epithelial cancer types, but the role of galectin-7 has ...

journal_title：Oncology letters

authors： Menkhorst E,Griffiths M,Van Sinderen M,Rainczuk K,Niven K,Dimitriadis E

更新日期：2018-10-01 00:00:00

abstract：:Prostate stem cell antigen (PSCA) is a glycosylphosphatidylinositol (GPI)-anchored cell surface protein and exhibits an organ-dependent expression pattern in cancer. PSCA is upregulated in prostate cancer and downregulated in gastric cancer. PSCA is expressed in a variety of human organs. Although certain studies prev...

journal_title：Oncology letters

authors： Ono H,Sakamoto H,Yoshida T,Saeki N

更新日期：2018-03-01 00:00:00

abstract：:MicroRNAs (miRs) can function as tumor suppressors or oncogenes in different types of human malignancy, and may provide an effective therapy for cancer. The expression and functions of miR-592 have previously been studied in relation to cancer. However, the expression and potential functions of miR-592 in hepatocellul...

journal_title：Oncology letters

authors： Wang W,Zhang H,Tang M,Liu L,Zhou Z,Zhang S,Wang L

更新日期：2017-05-01 00:00:00

abstract：:Low-grade myofibroblastic sarcoma (LGMS) is a distinct mesenchymal myofibroblastic malignancy. The tumor may occur at a variety of sites, but is particularly associated with the head and neck. Of the two maxillary sarcomas that were analyzed in the present study, one was misdiagnosed as an inflammatory myofibroblastic...

journal_title：Oncology letters

authors： Qiu JY,Liu P,Shi C,Han B

更新日期：2015-02-01 00:00:00

abstract：:Trefoil factor 2 (TFF2) plays a protective role in gastric mucosa and may be involved in the progression of gastric cancer, but the detailed functions and underlying molecular mechanisms are not clear. The present study used a combination of clinical observations and molecular methods to investigate the correlation be...

journal_title：Oncology letters

authors： Jiang P,Yu G,Zhang Y,Xiang Y,Zhu Z,Feng W,Lee W,Zhang Y

更新日期：2014-05-01 00:00:00

abstract：:Clear cell myoepithelial carcinoma is a very rare disease which develops primarily in the parotid gland. To date, only 17 cases of clear cell myoepithelial carcinoma have been reported worldwide. Among them, only three cases developed in the minor salivary gland in the oral cavity. No cases developed in the base of th...

journal_title：Oncology letters

authors： Park JH,Choi JY,Hong R,DO NY

更新日期：2012-12-01 00:00:00

abstract：:An elevated neutrophil to lymphocyte ratio (NLR) has been reported to be associated with the pathological response to neoadjuvant therapies in numerous types of cancer. The aim of the current study was to clarify the association between pre-treatment NLR and the pathological response to preoperative chemoradiotherapy ...

journal_title：Oncology letters

authors： Hasegawa S,Eguchi H,Tomokuni A,Tomimaru Y,Asaoka T,Wada H,Hama N,Kawamoto K,Kobayashi S,Marubashi S,Konnno M,Ishii H,Mori M,Doki Y,Nagano H

更新日期：2016-02-01 00:00:00

abstract：:Breast tissue is very sensitive to ionizing radiation due to the presence of reproductive hormones, including estrogen. In the present pilot study, the efficiency of mammography X-rays to induce DNA double strand breaks (DSB) in mammary epithelial cells was investigated. For this, freshly resected healthy breast tissu...

journal_title：Oncology letters

authors： Depuydt J,Viaene T,Blondeel P,Roche N,Van den Broecke R,Thierens H,Vral A

更新日期：2018-09-01 00:00:00

abstract：:Cancer/testis (CT) antigens are promising targets for immunotherapy due to their restricted expression in the germ cells of the testis in healthy tissue and high immunogenicity. The aim of the present study was to determine whether transmembrane protein 31 (TMEM31) is a CT antigen and to investigate the pattern of TME...

journal_title：Oncology letters

authors： Li J,Zou X,Li C,Zhong J,Chen Y,Zhang X,Qi F,Li M,Cai Z,Tang A

更新日期：2017-04-01 00:00:00

abstract：:A number of studies have revealed the usefulness of multimodal imaging in gliomas. Although the results have been heavily affected by the method used for region of interest (ROI) design, the most discriminatory method for setting the ROI remains unclear. The aim of the present study was to determine the most suitable ...

journal_title：Oncology letters

authors： Takano K,Kinoshita M,Arita H,Okita Y,Chiba Y,Kagawa N,Watanabe Y,Shimosegawa E,Hatazawa J,Hashimoto N,Fujimoto Y,Kishima H

更新日期：2018-05-01 00:00:00

abstract：:Retroperitoneal liposarcoma is a rare tumor with an incidence of 2.5 per million individuals. Early diagnosis is difficult as there is an absence of specific clinical presentations. The present case study reports a patient diagnosed with retroperitoneal liposarcoma who was treated by complete surgical resection and re...

journal_title：Oncology letters

authors： Zhang WD,Liu DR,Que RS,Zhou CB,Zhan CN,Zhao JG,Chen LI

更新日期：2015-07-01 00:00:00

abstract：:Hepatocellular carcinoma (HCC) is generally considered one of the most common gastrointestinal malignant tumors, characterized by high invasiveness and metastatic rate, as well as insidious onset. A relationship between carcinogenicity and aberrant microRNA-139-5p (miR-139-5p) expression has been identified in multipl...

journal_title：Oncology letters

authors： Qin H,Wen DY,Que Q,Zhou CY,Wang XD,Peng YT,He Y,Yang H,Liao BM

更新日期：2019-12-01 00:00:00

abstract：:Morphological response is considered an improved surrogate to the Response Evaluation Criteria in Solid Tumors (RECIST) model with regard to predicting the prognosis for patients with colorectal liver metastases. However, its use as a decision-making tool for surgical intervention has not been examined. The present st...

journal_title：Oncology letters

authors： Suzuki K,Muto Y,Ichida K,Fukui T,Takayama Y,Kakizawa N,Kato T,Hasegawa F,Watanabe F,Kaneda Y,Kikukawa R,Saito M,Tsujinaka S,Futsuhara K,Takata O,Noda H,Miyakura Y,Kiyozaki H,Konishi F,Rikiyama T

更新日期：2017-08-01 00:00:00

abstract：:Matrix metalloproteinases (MMPs) exhibit an important function in extracellular matrix degradation. MMPs modulate the activation of growth factors, cytokines and metastasis. At present, the effect of exercise on serum levels of MMP-2 and -9 remains unclear. The aim of the present study was to investigate the effect of...

journal_title：Oncology letters

authors： Giganti MG,Tresoldi I,Sorge R,Melchiorri G,Triossi T,Masuelli L,Lido P,Albonici L,Foti C,Modesti A,Bei R

更新日期：2016-09-01 00:00:00