Safety of bevacizumab in clinical practice for recurrent ovarian cancer: A retrospective cohort study.

abstract：:The aim of the present study was to observe the in vivo targeting characteristic of angiopoietin 2-small interfering RNA (Ang2-siRNA) plasmid/chitosan magnetic nanoparticles in an established nude mouse model of malignant melanoma (MM) under an external magnetic field. The nude mouse MM model was first established, th...

journal_title：Oncology letters

authors： Shan XY,Xu TT,Liu ZL,Hu XF,Zhang YD,Guo SZ,Wang B

更新日期：2017-08-01 00:00:00

abstract：:Effect of microRNA-27b (miR-27b) on cisplatin chemotherapy sensitivity of oral squamous cell carcinoma (OSCC) was investigated to provide a reference for clinical prevention of OSCC cell resistance. The clinical tissues of 34 patients with OSCC-resistant cancer and 28 patients with cisplatin-sensitive OSCC in Nanjing ...

journal_title：Oncology letters

authors： Liu B,Cao G,Dong Z,Guo T

更新日期：2019-07-01 00:00:00

abstract：:In the majority of acute promyelocytic leukemia (APL) cases, translocons produce a promyelocytic leukemia protein-retinoic acid receptor α (PML-RARα) fusion gene. Studies have reported that neutrophil elastase (NE) cleaves bcr-1-derived PML-RAα in early myeloid cells, leaving only the nuclear localization signal (NLS)...

journal_title：Oncology letters

authors： Wang H,Yang R,Zhong L,Zhu XY,Ma PP,Yang XQ,Jiang KL,Liu BZ

更新日期：2017-04-01 00:00:00

abstract：:Impairment of microRNA (miRNA) biogenesis may be involved in clear cell renal cell carcinoma (ccRCC). The objective of the present study was to investigate the mRNA levels of important miRNA machinery components, DICER1, DROSHA, DiGeroge syndrome critical region gene 8 (DGCR8), and Argonaute 2 (AGO2), and their correl...

journal_title：Oncology letters

authors： Lee SS,Min H,Ha JY,Kim BH,Choi MS,Kim S

更新日期：2019-10-01 00:00:00

abstract：:Colorectal cancer (CRC) is one of the most prevalent malignancies worldwide and remains the third leading cause of cancer-associated mortality. The present study aimed to fully elucidate the pathogenesis of CRC and identify associated genes in tumor development. Microarray GSE44076, GSE41328 and GSE44861 datasets were...

journal_title：Oncology letters

authors： Shen X,Yue M,Meng F,Zhu J,Zhu X,Jiang Y

更新日期：2016-11-01 00:00:00

abstract：:Glioma is one of the most prevalent types of malignancy in the central nervous system worldwide, and the prognosis of patients with late stage glioma remains poor. Thus, the development of promising therapeutic strategies against glioma is essential. Long non-coding RNAs (lncRNAs) are functional RNA molecules involved...

journal_title：Oncology letters

authors： Guan N,Wang R,Feng X,Li C,Guo W

更新日期：2020-09-01 00:00:00

abstract：:The present study aimed to evaluate the effects of amentoflavone on sorafenib-induced apoptosis in sorafenib-resistant hepatocellular carcinoma (HCC) cells. The sorafenib-resistant SK-Hep1 (SK-Hep1R) cell line was established for the present study. Initially, the differences in sorafenib-induced cytotoxicity and apopt...

journal_title：Oncology letters

authors： Chen WL,Hsieh CL,Chen JH,Huang CS,Chen WT,Kuo YC,Chen CY,Hsu FT

更新日期：2017-09-01 00:00:00

abstract：:The aim of the present study was to analyze potential therapy targets for prostate cancer using integrated analysis of two gene expression profiles. First, gene expression profiles GSE38241 and GSE3933 were downloaded from the Gene Expression Omnibus database. Differentially expressed genes (DEGs) between prostate can...

journal_title：Oncology letters

authors： Zhao R,Wang Y,Zhang M,Gu X,Wang W,Tan J,Wei X,Jin N

更新日期：2017-11-01 00:00:00

abstract：:Angiosarcoma is a rare and deadly malignancy originating from the vascular endothelial cells. Surgery is the most effective method to cure this disease, but for metastatic angiosarcoma, a chemotherapy-based treatment is the main therapeutic choice. However, there is currently no standard chemotherapy regimen. The curr...

journal_title：Oncology letters

authors： Ye J,Li XF,Wang YD,Yuan Y

更新日期：2015-04-01 00:00:00

abstract：:The aim of the present study was to investigate the expression and role of microRNA-26a (miR-26a) in lung cancer, and to verify whether differentially expressed in adenocarcinoma of the lung (DAL-1) is the target protein of miR-26a. mRNA expression levels of miR-26a and DAL-1 were detected using reverse transcription-...

journal_title：Oncology letters

authors： Cai T,Guan X,Wang H,Fang Y,Long J,Xie X,Zhang Y

更新日期：2018-04-01 00:00:00

abstract：:The aim of this study was to investigate the correlation between H-ras mutation and primary hepatocellular carcinoma (HCC) and to describe the role of H-ras mutation in carcinogenesis. Clinical samples of 69 patients were collected and the expression levels of H-ras in HCC and the surrounding normal tissues were exami...

journal_title：Oncology letters

authors： Sui G,Ma X,Liu S,Niu H,Dong Q

更新日期：2012-10-01 00:00:00

abstract：:Renal oncocytoma is one of the most unusual benign lesion, which are usually diagnosed postoperatively, since their differentiation from renal cell carcinoma is challenging. The present study reports two cases of renal oncocytoma in a 60-year-old woman and a 46-year-old man. Relevant clinical and pathological data on ...

journal_title：Oncology letters

authors： Wang Y,Hu YU,Zhai X,Wang W,Dong B,Zhou H

更新日期：2016-07-01 00:00:00

abstract：:There is a growing body of evidence indicating that several melanoma-associated antigen-A (MAGE-A) subgroups contribute to the malignancy of head and neck cancer. The present study retrospectively analyzed the expression of all known MAGE-A subgroups in the tumor front and center of 38 head and neck cancer patients (U...

journal_title：Oncology letters

authors： Hartmann S,Brisam M,Rauthe S,Driemel O,Brands RC,Rosenwald A,Kübler AC,Müller-Richter UD

更新日期：2016-10-01 00:00:00

abstract：:Head and neck squamous cell carcinoma (HNSCC), one of the most common malignant tumors, endangers human health. Recently, the incidence of HNSCC has kept increasing: However, its prognosis has not significantly improved. Understanding the molecular mechanism underlying HNSCC development will therefore provide new stra...

journal_title：Oncology letters

authors： Zou B,Guan X,Zhang W,Wang D,Xu K,Yuan DY,Meng Z,Zhang B

更新日期：2019-12-01 00:00:00

abstract：:Ecto-5'-nucleotidase [cluster of differentiation (CD)73] has important functions in several types of cancer, however, its expression in squamous cell carcinoma (SCC) remains unknown. The present study was designed to investigate CD73 expression in SCC. CD73 expression was assessed by immunohistochemistry in 113 patien...

journal_title：Oncology letters

authors： Ren ZH,Yuan YX,Ji T,Zhang CP

更新日期：2016-07-01 00:00:00

abstract：:Clear cell myoepithelial carcinoma is a very rare disease which develops primarily in the parotid gland. To date, only 17 cases of clear cell myoepithelial carcinoma have been reported worldwide. Among them, only three cases developed in the minor salivary gland in the oral cavity. No cases developed in the base of th...

journal_title：Oncology letters

authors： Park JH,Choi JY,Hong R,DO NY

更新日期：2012-12-01 00:00:00

abstract：:The present study sought to characterize the role of macrophage inflammatory protein-3α (MIP-3α) in non-small cell lung cancer (NSCLC) patients with early recurrence or metastasis after primary pulmonary resection. Follow-up examinations were conducted for 203 NSCLC patients with primary pulmonary resection for two ye...

journal_title：Oncology letters

authors： Zhang X,Meng A,Wang H,Yan X

更新日期：2014-08-01 00:00:00

abstract：:The aim of this study was to evaluate potential predictive factors in the treatment of limited-disease small cell lung cancer (LD-SCLC). A total of 33 patients with LD-SCLC who underwent definitive chemoradiotherapy at our institute between April 1996 and May 2007 were enrolled in our retrospective study. The relation...

journal_title：Oncology letters

authors： Komatsu T,Oizumi Y,Kunieda E,Tamai Y,Akiba T,Kogawa A

更新日期：2011-09-01 00:00:00

abstract：:The present study aimed to measure the expression of WNT1 in ameloblastoma (AB). Immunohistochemistry was used to observe changes in WNT1 expression in 80 AB samples, 10 keratocystic odontogenic tumor (KCOT) samples and 10 normal oral mucosa (NOM) samples. Western blotting and reverse transcription-quantitative polyme...

journal_title：Oncology letters

authors： Wang GN,Zhong M,Chen Y,Ji J,Gao XQ,Wang TF

更新日期：2018-08-01 00:00:00

abstract：:Sex determining region Y-box 2 (SOX2) is a transcription factor that serves a role in numerous different types of malignant cancer. Altered expression of chloride channel proteins has been described in a variety of malignancies. However, the association between SOX2 and chloride channel proteins is not yet fully under...

journal_title：Oncology letters

authors： Chen J,Wang F,Lu Y,Yang S,Chen X,Huang Y,Lin X

更新日期：2020-12-01 00:00:00

abstract：:Nanoparticle albumin-bound (nab)-paclitaxel appears to exhibit better response rates in patients with metastatic urothelial cancer of the bladder whom are pretreated with nab-paclitaxel compared with conventional paclitaxel. Paclitaxel may induce multidrug resistance in patients with cancer, while the mechanisms of re...

journal_title：Oncology letters

authors： Vallo S,Köpp R,Michaelis M,Rothweiler F,Bartsch G,Brandt MP,Gust KM,Wezel F,Blaheta RA,Haferkamp A,Cinatl J Jr

更新日期：2017-06-01 00:00:00

abstract：:Pancreatic ductal adenocarcinoma (PDA) is an aggressive malignant disease that is resistant to various chemotherapeutic agents and commonly relapses. Efficient elimination of metastasized PDA is critical for a positive post-surgical treatment outcome. The present study analyzed the effect of the B-cell lymphoma-2 (Bcl...

journal_title：Oncology letters

authors： Kasai S,Sasaki T,Watanabe A,Nishiya M,Yasuhira S,Shibazaki M,Maesawa C

更新日期：2017-07-01 00:00:00

abstract：:In recent decades, thyroid cancer (TC) has become one of the most common endocrine malignancies. Next-generation sequencing of paired TC and adjacent healthy thyroid tissues demonstrated that polycystic kidney and hepatic disease 1-like 1 (PKHD1L1) may serve as a tumour suppressor gene in thyroid cancer. However, the ...

journal_title：Oncology letters

authors： Zheng C,Quan R,Xia EJ,Bhandari A,Zhang X

更新日期：2019-09-01 00:00:00

abstract：:Ovarian endometrioid borderline tumors (EBTs) are extremely rare, and are thought to be precursors of endometrioid carcinoma, beginning as adenofibroma or endometriosis and progressing in a slow, stepwise manner. In endometrioid carcinomas, a high frequency of activating mutations in phosphatase and tensin homolog (PT...

journal_title：Oncology letters

authors： Nakamura K,Nakayama K,Ishikawa M,Minamoto T,Ishibashi T,Sato E,Sanuki K,Yamashita H,Ono R,Iida K,Sultana R,Hossain MM,Ishikawa N,Kyo S

更新日期：2018-07-01 00:00:00

abstract：:Pulmonary tumor thrombotic microangiopathy (PTTM) is an uncommon cancer-related complication characterized by intimal proliferation in pulmonary small arteries and arterioles with or without tumor emboli. In the majority of cases, the causative lesion is gastric poorly differentiated adenocarcinoma. In the present stu...

journal_title：Oncology letters

authors： Hotta M,Ishida M,Kojima F,Iwai Y,Okabe H

更新日期：2011-05-01 00:00:00

abstract：:[This corrects the article DOI: 10.3892/ol.2017.6360.]. ...

journal_title：Oncology letters

authors： Liu X,Guo H,Wei Y,Cai C,Zhang B,Li J

更新日期：2021-02-01 00:00:00

abstract：:The aim of the present study was to investigate the feasibility and value of serum microRNAs (miRNAs/miRs) as biological markers for the prediction of the behavior and prognosis of esophageal squamous cell cancer (ESCC). The differential expression of serum miRNA was detected by an miRNA microarray of 9 patients with ...

journal_title：Oncology letters

authors： Hui B,Chen X,Hui L,Xi R,Zhang X

更新日期：2015-11-01 00:00:00

abstract：:Cancer metastasis, particularly multiple metastatic cancer, is a significant event that affects patient prognosis. However, single metastasis can be treated by partial resection, although the clinicopathological and molecular profile of single lung metastasis has not been thoroughly elucidated. The present study exami...

journal_title：Oncology letters

authors： Yanai Y,Hayashi T,Akazawa Y,Yatagai N,Tsuyama S,Yao T,Saito T

更新日期：2020-07-01 00:00:00

abstract：:The aim of the present study was to assess the expression of microRNA-146a (miR-146a) in human lung adenocarcinoma cells, its effect on cellular behaviors, and the underlying molecular mechanisms. Reverse transcription-quantitative PCR (RT-qPCR) was used to measure miR-146a expression in the human normal lung epitheli...

journal_title：Oncology letters

authors： Yuan F,Zhang S,Xie W,Yang S,Lin T,Chen X

更新日期：2020-06-01 00:00:00

abstract：:[This corrects the article DOI: 10.3892/ol.2018.8006.]. ...

journal_title：Oncology letters

authors： Xu F,Zhu Y,Lu Y,Yu Z,Zhong J,Li Y,Pan J

更新日期：2020-11-01 00:00:00