Location of NLS-RARα protein in NB4 cell and nude mice.

abstract：:Anaplastic thyroid carcinoma is a significantly fatal endocrine neoplasm, with an average survival time of 4-12 months following diagnosis. The present study reports the case of a 57-year-old male patient who presented to the Bağcılar Training and Research Hospital (Istanbul, Turkey) due to swelling in the neck and di...

journal_title：Oncology letters

authors： Altinay S,Taş B,Ozen A,Süt PA

更新日期：2014-06-01 00:00:00

abstract：:The aim of this study was to objectively evaluate the benefits of laparoscopically assisted vaginal radical hysterectomy and lymphadenectomy for early-stage cervical cancer. Clinical data were prospectively collected from patients with IA-IIB cervical cancer who underwent laparoscopically assisted vaginal radical hyst...

journal_title：Oncology letters

authors： Hou CY,Li XL,Jiang F,Gong RJ,Guo XY,Yao YQ

更新日期：2011-07-01 00:00:00

abstract：:Melanoma is the most common primary intraocular malignancy and metastasis of melanoma to other organs often results in a poor prognosis. ADP-ribosyltransferase 3 (ART3) is involved in cell division and DNA repair. However, its biological function in melanoma remains unclear. In the present study, it was identified tha...

journal_title：Oncology letters

authors： He J,Li Y,Wang Y,Zhang H,Ge S,Fan X

更新日期：2018-05-01 00:00:00

abstract：:Pancreatic cancer has a low survival rate globally. Anillin (ANLN) is involved in the pathogenesis of pancreatic cancer (PC). The present study used databases and reverse transcription-quantitative PCR to investigate the association between ANLN expression, clinical variables and the survival rate of patients with pan...

journal_title：Oncology letters

authors： Nie Y,Zhao Z,Chen M,Ma F,Fan Y,Kang Y,Kang B,Wang C

更新日期：2021-02-01 00:00:00

abstract：:The present study aimed to investigate the imaging characteristics of primary malignant bone tumors in children. The imaging results of 34 children with primary malignant bone tumors confirmed by histopathological diagnosis between March 2008 and January 2014 were retrospectively analyzed. In total, 25 patients had os...

journal_title：Oncology letters

authors： Sun Y,Liu X,Pan S,Deng C,Li X,Guo Q

更新日期：2017-11-01 00:00:00

abstract：:The aim of this study was to investigate the correlation between cyclin A expression and efficacy of paclitaxel-based chemotherapy in patients with esophageal squamous cell carcinoma (ESCC). The expression of cyclin A was examined in 48 newly diagnosed ESCC patients prior to treatment using the MaxVision immunohistoch...

journal_title：Oncology letters

authors： Huang JX,Shen SL,Lin M,Xiao W,Chen WC,Lin MS,Yu H,Chen P,Qian RY

更新日期：2012-10-01 00:00:00

abstract：:The current study reports the case of a large retroperitoneal tumor treated with modified simultaneous integrated boost (SIB) radiotherapy. A 45-year-old female presented to the emergency department complaining of left abdominal pain and fever. A computed tomography scan detected a retroperitoneal tumor of 12×16×16 cm...

journal_title：Oncology letters

authors： Nomiya T,Akamatsu H,Harada M,Ota I,Hagiwara Y,Ichikawa M,Miwa M,Mizutani M,Kato T,Nagaoka A,Tomita Y,Nemoto K

更新日期：2015-06-01 00:00:00

abstract：:We present the case of a patient with a solitary left frontoparietal brain metastasis of melanoma previously treated with surgery. Three months later, the patient was admitted to the emergency room in a confusional state with meningeal signs. A cerebrospinal fluid (CSF) test and magnetic resonance imaging findings sug...

journal_title：Oncology letters

authors： Moyano MS,Gutiérrez-Gutiérrez G,Rodríguez-Esteban I,Crespo GS,Casado E

更新日期：2010-11-01 00:00:00

abstract：:Nordihydroguaiaretic acid (NDGA) and its derivatives possess anti-cancer effects on various types of cancer via the induction of apoptosis or cell cycle arrest. This study proved that NDGA inhibited cervical cancer SiHa cell growth and induced cell cycle arrest at the G(1) phase, which may be a consequence of cell cyc...

journal_title：Oncology letters

authors： Gao P,Zhai F,Guan L,Zheng J

更新日期：2011-01-01 00:00:00

abstract：:Despite advancements in treatment regimens, the mortality rate of patients with oral tongue squamous cell carcinoma (OTSCC) is high. In addition, the signaling pathways and oncoproteins involved in OTSCC progression remain largely unknown. Therefore, the aim of the present study was to identify specific prognostic mar...

journal_title：Oncology letters

authors： Zhong P,Liu L,Shen A,Chen Z,Hu X,Cai Y,Lin J,Wang B,Li J,Chen Y,Peng J

更新日期：2019-12-01 00:00:00

abstract：:Although there is evidence that galectin-9 is a critical factor in health and disease, the upstream regulatory microRNA (miRNA or miR) of the protein remains poorly defined. miR-455-5p is characterized as a tumor-associated miRNA in cancer research. However, the actual role of miR-455-5p with respect to inhibiting or ...

journal_title：Oncology letters

authors： Yang Q,Hou C,Huang D,Zhuang C,Jiang W,Geng Z,Wang X,Hu L

更新日期：2017-03-01 00:00:00

abstract：:A 72-year-old man initially presented with lumbar and right chest pain, but was later found out to also have an elevated prostate-specific antigen (PSA) level at 2,000.0 ng/ml. Further evaluation disclosed metastatic prostate cancer involving the bones and lymph nodes. The patient was initially treated with combined a...

journal_title：Oncology letters

authors： Kato T,Komiya A,Yuasa J,Kaga K,Kaga M,Kojima S,Naya Y,Isaka S

更新日期：2018-02-01 00:00:00

abstract：:Primary hemangioendotheliomas (HEs) of the spleen are rare, low-grade borderline-malignant vascular tumors. To date, only a few splenic HE cases have been reported in adults. In infants, one 9-year-old male patient has previously been reported, and the patient succumbed to the disease shortly following surgery. Curren...

journal_title：Oncology letters

authors： Wang Z,Zhang L,Zhang B,Mu D,Cui K,Li S

更新日期：2015-01-01 00:00:00

abstract：:The present case study reported of amelanotic malignant melanoma of the esophagus. A 68-year-old man underwent laparoscopic distal gastrectomy for early gastric cancer diagnosis. After gastrectomy, endoscopic examination revealed a protruded lesion lying adjacent to the melanosis area of the esophagus. Histology of th...

journal_title：Oncology letters

authors： Kobayashi J,Fujimoto D,Murakami M,Hirono Y,Goi T

更新日期：2018-06-01 00:00:00

abstract：:The histological subtype of non-small-cell lung cancer (NSCLC) is a significant factor when selecting treatment strategies. However, cases are occasionally encountered that are diagnosed as 'not otherwise specified' (NOS) prior to surgery, due to an uncertain histological subtype. The present study investigated the pr...

journal_title：Oncology letters

authors： Tane S,Nishio W,Ogawa H,Hokka D,Tane K,Tanaka Y,Tauchi S,Uchino K,Sakai Y,Ohbayashi C,Yoshimura M,Maniwa Y

更新日期：2014-09-01 00:00:00

abstract：:The present study aimed to investigate the anticancer effect of aloe-emodin, an anthraquinone compound present in the leaves of Aloe vera, on two human colon carcinoma cell lines, DLD-1 and WiDr. Colon carcinoma cells were treated with various concentrations of aloe-emodin for different durations. Cell viability was m...

journal_title：Oncology letters

authors： Lin KY,Uen YH

更新日期：2010-05-01 00:00:00

abstract：:Epidermal growth factor receptor (EGFR)-tyrosine kinase inhibitors (TKIs) are an approved first-line therapy against unresectable or advanced non-small cell lung cancer (NSCLC) harboring EGFR gene activating mutations. However, the majority of tumors develop acquired resistance against EGFR-TKIs and some tumors exhibi...

journal_title：Oncology letters

authors： Yamaura T,Muto S,Mine H,Takagi H,Watanabe M,Ozaki Y,Inoue T,Fukuhara M,Okabe N,Matsumura Y,Hasegawa T,Osugi J,Hoshino M,Higuchi M,Shio Y,Suzuki H

更新日期：2020-06-01 00:00:00

abstract：:The present study aimed to examine whether serum microRNA (miR)-22 may be considered a potential biomarker to differentiate patients with papillary thyroid cancer (PTC) from healthy controls. Reverse transcription-quantitative polymerase chain reaction demonstrated that serum miR-22 expression was significantly enhanc...

journal_title：Oncology letters

authors： Wang D,Guo C,Kong T,Mi G,Li J,Sun Y

更新日期：2019-03-01 00:00:00

abstract：:With the growing requirement for novel prognostic biomarkers for pancreatic cancer, many studies have focused on clinical and/or genomic variables. Although many studies have been performed, carbohydrate antigen 19-9 is the only biomarker in clinical use. Therefore, the present study examined whether γ-secretase genes...

journal_title：Oncology letters

authors： Jeon YH,Ha M,Kim SW,Kim MJ,Lee CS,Oh CK,Han ME,Oh SO,Kim YH

更新日期：2019-05-01 00:00:00

abstract：:The present study aimed to investigate the effects of silencing RIP1 by small interfering RNA (siRNA) on the biological behavior of the LoVo human colorectal carcinoma cell line and to provide evidence for the feasibility of colorectal cancer gene therapy. LoVo cells were divided into the RIP1 siRNA group, the blank c...

journal_title：Oncology letters

authors： You HX,Zhou YH,Tan SY,She TH

更新日期：2014-06-01 00:00:00

abstract：:Askin tumors are rare malignant neoplasms that are localized in the thoracopulmonary region and mainly occur in children and adolescents. Further investigation with regard to the effective treatment of this disease is required, since the disease has a low incidence and limited knowledge is available on the biological ...

journal_title：Oncology letters

authors： Dou X,Yan H,Wang R

更新日期：2013-10-01 00:00:00

abstract：:Percutaneous transluminal angioplasty using balloon catheters for Budd-Chiari syndrome (BCS) and transcatheter arterial chemoembolization (TACE) for unresectable hepatocellular carcinoma (HCC) have become increasingly accepted as alternative therapeutic modalities. However, few studies have investigated the clinical e...

journal_title：Oncology letters

authors： Zhang QQ,Zu MH,Xu H,Gu YM,Wang WL,Gao ZK

更新日期：2013-08-01 00:00:00

abstract：:Resistance to oxaliplatin (L-OHP) is a major obstacle to successful chemotherapy in colorectal cancer (CRC). In the present study, the ability of gambogic acid (GA) to reverse L-OHP resistance in CRC LoVo cells was investigated. L-OHP-resistant LoVo/L-OHP cells were established by exposing them to increasing concentra...

journal_title：Oncology letters

authors： Wang Q,Wei J,Wang C,Zhang T,Huang D,Wei F,He F,Cai W,Yang P,Zeng S,Li W,Cao J

更新日期：2018-08-01 00:00:00

abstract：:Carbohydrate antigen 19-9 (CA19-9) is not generally considered to be a biomarker in pancreatic neuroendocrine tumors (pNETs), as the majority of pNETs present with a normal range of CA19-9. The present study aimed to evaluate the role of serum CA19-9 levels as a prognostic factor in a relatively large number of patien...

journal_title：Oncology letters

authors： Luo G,Jin K,Cheng H,Liu C,Guo M,Lu Y,Yang C,Xu J,Wang W,Gao H,Zhang S,Long J,Xu J,Ni Q,Chen J,Yu X

更新日期：2017-12-01 00:00:00

abstract：:MicroRNA-1470 (miR-1470) is overexpressed in esophageal squamous cell carcinoma (ESCC); however, its role and underlying molecular mechanism remain unknown. The aim of the present study was to explore the tumorigenic role and mechanism of miR-1470 overexpression in ESCC. The expression of miR-1470 in ESCC tissues and ...

journal_title：Oncology letters

authors： Mei LL,Qiu YT,Wang WJ,Bai J,Shi ZZ

更新日期：2017-12-01 00:00:00

abstract：:Wild-type p53-induced phosphatase (Wip1) is a member of the protein phosphatase type 2C family and is an established oncogene due to its dephosphorylation of several tumor suppressors and negative control of the DNA damage response system. It has been reported to dephosphorylate p53, ataxia telangiectasia mutated, che...

journal_title：Oncology letters

authors： Wang ZP,Tian Y,Lin J

更新日期：2017-10-01 00:00:00

abstract：:The expression of human transfer ribonucleic acid (tRNA) methyltransferase 9-like (KIAA1456) protein in lung cancer tissue and its effects on certain genes involved in the proliferation, migration and invasion of lung cancer cells were investigated. Immunohistochemistry was applied to stain lung cancer tissue and adja...

journal_title：Oncology letters

authors： Wang S,Liu X,Huang J,Zhang Y,Sang C,Li T,Yuan J

更新日期：2018-09-01 00:00:00

abstract：:There is a growing body of evidence indicating that several melanoma-associated antigen-A (MAGE-A) subgroups contribute to the malignancy of head and neck cancer. The present study retrospectively analyzed the expression of all known MAGE-A subgroups in the tumor front and center of 38 head and neck cancer patients (U...

journal_title：Oncology letters

authors： Hartmann S,Brisam M,Rauthe S,Driemel O,Brands RC,Rosenwald A,Kübler AC,Müller-Richter UD

更新日期：2016-10-01 00:00:00

abstract：:The aim of the present study was to investigate the role of edema surrounding breast cancer masses in the prognostic prediction of magnetic resonance imaging (MRI) T2-weighted fat suppression sequence. For this purpose, 80 patients with mass-type breast cancer underwent conventional plain breast MRI, dynamic contrast-...

journal_title：Oncology letters

authors： Liang T,Hu B,Du H,Zhang Y

更新日期：2020-12-01 00:00:00

abstract：:In previous studies, we observed that STAT1 and Survivin correlated negatively with gastric cancer tissues, and that the functions of the IFN-γ-STAT1 pathway and Survivin in gastric cancer are the same as those reported for other types of cancer. In this study, the SGC7901 gastric cancer cell line and 83 gastric cance...

journal_title：Oncology letters

authors： Deng H,Zhen H,Fu Z,Huang X,Zhou H,Liu L

更新日期：2012-01-01 00:00:00