Treatment of an Askin tumor: A case report and review of the literature.

abstract：:Nasopharyngeal carcinoma (NPC) is a common malignancy of the head and neck. The aim of the present study was to conduct an integrated bioinformatics analysis of differentially expressed genes (DEGs) and to explore the molecular mechanisms of NPC. Two profiling datasets, GSE12452 and GSE34573, were downloaded from the ...

journal_title：Oncology letters

authors： Zou Z,Gan S,Liu S,Li R,Huang J

更新日期：2019-07-01 00:00:00

abstract：:Ovarian cancer is the most malignant gynecologic neoplasm in women and has the worst prognosis of all cancer types in women based on the 5-year survival rates. A previous study indicated that mangiferin exerts an anti-neoplastic effect on human ovarian cancer cells by targeting Notch3. Additionally, it has been demons...

journal_title：Oncology letters

authors： He W,You Y,Du S,Lei T,Wang H,Li X,He X,Tong R,Wang Y

更新日期：2019-01-01 00:00:00

abstract：:Targeted therapy of non-small cell lung cancer (NSCLC) patients with mutations in the epidermal growth factor receptor (EGFR) gene has been associated with improved prognosis. However, there is a shortage on data from real-world clinical practice in management of EGFR-positive NSCLC patients in Poland. The present stu...

journal_title：Oncology letters

authors： Ramlau R,Krawczyk P,Dziadziuszko R,Chmielewska I,Milanowski J,Olszewski W,Stencel K,Ramlau-Piątek K,Segiet A,Skroński M,Grudny J,Chorostowska-Wynimko J

更新日期：2017-11-01 00:00:00

abstract：:The aim of the present study was to evaluate the curative effect of fludeoxyglucose-positron emission tomography/computed tomography (18F-FDG-PET/CT)-guided intensity-modulated radiotherapy (IMRT) for 42 patients with International Federation of Gynecology and Obstetrics (FIGO) stage III/IV ovarian cancer. Between Jan...

journal_title：Oncology letters

authors： Dang YZ,Li X,Ma YX,Li XL,Yang T,Lu WL,Huang SG

更新日期：2019-01-01 00:00:00

abstract：:Manganese superoxide dismutase (MnSOD) promotes invasive and migratory activities by upregulating Forkhead box protein M1 (FoxM1) expression. The present study investigated whether modulation of MnSOD and FoxM1 expression was responsible for the antitumor effects of genistein on cancer stem-like cells (CSLCs) derived ...

journal_title：Oncology letters

authors： Fu Z,Cao X,Liu L,Cao X,Cui Y,Li X,Quan M,Ren K,Chen A,Xu C,Qiu Y,Chen X,Wang Z,Cao J

更新日期：2020-09-01 00:00:00

abstract：:The aim of the present study was to establish a prediction index (PI) model for the 5-year survival rate of patients with hepatitis B-related hepatocellular carcinoma (HCC) after radical resection, and to evaluate the effect of prophylactic transcatheter arterial chemoembolization (TACE). A total of 201 patients with ...

journal_title：Oncology letters

authors： He S,Fan X,Ma H,Xiaerfuhazi H,Rehato A,Feng J,Shi X,He F

更新日期：2019-08-01 00:00:00

abstract：:The aim of the present study was to investigate the expression and role of microRNA-26a (miR-26a) in lung cancer, and to verify whether differentially expressed in adenocarcinoma of the lung (DAL-1) is the target protein of miR-26a. mRNA expression levels of miR-26a and DAL-1 were detected using reverse transcription-...

journal_title：Oncology letters

authors： Cai T,Guan X,Wang H,Fang Y,Long J,Xie X,Zhang Y

更新日期：2018-04-01 00:00:00

abstract：:The present study aimed to evaluate regional liver function impairment following transcatheter arterial chemoembolization (TACE), assessed by magnetic resonance imaging (MRI) enhanced by gadolinium ethoxybenzyl diethylenetriamine pentaacetic acid (Gd-EOB-DTPA). Additionally, this study evaluated the associations betwe...

journal_title：Oncology letters

authors： Xiao YD,Paudel R,Liu H,Zhang B,Ma C,Zhou SK

更新日期：2015-03-01 00:00:00

abstract：:Chronic hepatitis B virus (HBV) is the leading cause of hepatocellular carcinoma (HCC). Covalently closed circular DNA (cccDNA) is an intermediate in the life cycle of HBV. HBV-encoded X protein (HBx), a key viral oncoprotein, can be specifically ubiquitylated by male specific lethal 2 (MSL2), which causes upregulatio...

journal_title：Oncology letters

authors： Jin XL,Hong SK,Kim H,Lee SK,Yi NJ,Lee KW,Suh KS

更新日期：2019-11-01 00:00:00

abstract：:In recent decades, thyroid cancer (TC) has become one of the most common endocrine malignancies. Next-generation sequencing of paired TC and adjacent healthy thyroid tissues demonstrated that polycystic kidney and hepatic disease 1-like 1 (PKHD1L1) may serve as a tumour suppressor gene in thyroid cancer. However, the ...

journal_title：Oncology letters

authors： Zheng C,Quan R,Xia EJ,Bhandari A,Zhang X

更新日期：2019-09-01 00:00:00

abstract：:In order to study the influence and mechanism of miR-544a on the self-renewal ability of lung cancer stem cells, TargetScan was used to predict the target gene of miR-544a. A luciferase reporter system and western blotting were used to validate the target genes identified by TargetScan. 95C and 95D low and high metast...

journal_title：Oncology letters

authors： Mo XM,Li HH,Liu M,Li YT

更新日期：2014-10-01 00:00:00

abstract：:Interleukins (ILs) are involved in the occurrence and development of numerous types of cancer, and serve a critical role in the development of effective cancer therapeutics. The aim of the present study was to investigate the effect of IL-27 on chemotherapy resistance in lung cancer cells, and analyze its potential mo...

journal_title：Oncology letters

authors： Jiang B,Shi W,Li P,Wu Y,Li Y,Bao C

更新日期：2021-01-01 00:00:00

abstract：:Intramuscular myxoma (IM) is a benign intramuscular neoplasm composed of fibroblasts and abundant myxoid stroma. IMs most commonly affect larger skeletal muscles, while those affecting the oral and maxillofacial regions are rare, with a small number of documented cases in the available literature. The aim of the prese...

journal_title：Oncology letters

authors： Li G,Jiang W,Li W,Li J

更新日期：2014-05-01 00:00:00

abstract：:Ubiquitin-conjugating enzyme E2T (UBE2T), a member of the ubiquitin-conjugating E2 family in the ubiquitin-proteasome pathway, has been reported to be overexpressed in certain tumor types and to have an important role in the Fanconi anemia pathway. In the present study, the expression of UBE2T and its association with...

journal_title：Oncology letters

authors： Gong YQ,Peng D,Ning XH,Yang XY,Li XS,Zhou LQ,Guo YL

更新日期：2016-12-01 00:00:00

abstract：:The aim of the present study was to investigate the underlying molecular mechanisms of the potent cell cycle inhibition and apoptotic effect of luteolin on LoVo human colon cancer cells. In the present study, Cell Counting kit-8 assay revealed that luteolin exerted notable cytotoxicity on LoVo cells in a dose- and tim...

journal_title：Oncology letters

authors： Chen Z,Zhang B,Gao F,Shi R

更新日期：2018-02-01 00:00:00

abstract：:Significant antitumor activity of Momordica anti-human immunodeficiency virus protein of 30 kDa (MAP30) purified from Momordica charantia has been the subject of previous research. However, the effective mechanism of MAP30 on malignant glioma cells has not yet been clarified. The aim of the present study was to invest...

journal_title：Oncology letters

authors： Jiang Y,Miao J,Wang D,Zhou J,Liu B,Jiao F,Liang J,Wang Y,Fan C,Zhang Q

更新日期：2018-04-01 00:00:00

abstract：:Hepatic epithelioid angiomyolipoma (EAML) is a rare type of hepatic tumor. Due to a lack of adequate understanding about this tumor, hepatic EAML is often misdiagnosed as other diseases with similar clinical characteristics such as hepatic cancer. In the present study, 3 cases of hepatic EAML are reported, and the mai...

journal_title：Oncology letters

authors： Liu W,Meng Z,Liu H,Li W,Wu Q,Zhang X,E C

更新日期：2016-06-01 00:00:00

abstract：:Glutathione transferase Mu 1 (GSTM1) induces cancer drug resistance by hydrolyzing cancer chemotherapeutics or activating the anti-apoptosis pathway. However, the chemoresistance-inducing mechanism of GSTM1 in hepatocellular carcinoma (HCC) remains unknown. In the present study, the expression of GSTM1 was examined in...

journal_title：Oncology letters

authors： Fu XT,Song K,Zhou J,Shi YH,Liu WR,Tian MX,Jin L,Shi GM,Gao Q,Ding ZB,Fan J

更新日期：2018-07-01 00:00:00

abstract：:Toll-like receptor 4 (TLR4) and the interleukin (IL)-23/IL-17A axis serve an important role in tumor immunology. In the present study, the activation of the TLR4/myeloid differentiation primary response 88 (MyD88)-mediated signal transduction pathway in human hepatocellular carcinoma (HCC) cells was examined using imm...

journal_title：Oncology letters

authors： Kang Y,Su G,Sun J,Zhang Y

更新日期：2018-06-01 00:00:00

abstract：:The periostin protein, encoded by the POSTN gene, is a component of the extracellular matrix, which is expressed by fibroblasts and has been observed in a variety of human malignancies. The present study aimed to detect the expression of periostin in the tissues of non-small cell lung cancer (NSCLC) patients and benig...

journal_title：Oncology letters

authors： Hong LZ,Wei XW,Chen JF,Shi Y

更新日期：2013-12-01 00:00:00

abstract：:Resistance to oxaliplatin (L-OHP) is a major obstacle to successful chemotherapy in colorectal cancer (CRC). In the present study, the ability of gambogic acid (GA) to reverse L-OHP resistance in CRC LoVo cells was investigated. L-OHP-resistant LoVo/L-OHP cells were established by exposing them to increasing concentra...

journal_title：Oncology letters

authors： Wang Q,Wei J,Wang C,Zhang T,Huang D,Wei F,He F,Cai W,Yang P,Zeng S,Li W,Cao J

更新日期：2018-08-01 00:00:00

abstract：:Hepatocellular carcinoma (HCC) can result from hepatitis B or C infection, fibrosis or cirrhosis. Transforming growth factor-β (TGF-β) is one of the main growth factors associated with fibrosis or cirrhosis progression in the liver, but its role is controversial in hepatocarcinogenesis. In the present study, the effec...

journal_title：Oncology letters

authors： Kim JB,Lee S,Kim HR,Park SY,Lee M,Yoon JH,Kim YJ

更新日期：2018-06-01 00:00:00

abstract：:Hepatocellular carcinoma (HCC) is generally considered one of the most common gastrointestinal malignant tumors, characterized by high invasiveness and metastatic rate, as well as insidious onset. A relationship between carcinogenicity and aberrant microRNA-139-5p (miR-139-5p) expression has been identified in multipl...

journal_title：Oncology letters

authors： Qin H,Wen DY,Que Q,Zhou CY,Wang XD,Peng YT,He Y,Yang H,Liao BM

更新日期：2019-12-01 00:00:00

abstract：:Epithelial ovarian cancer has the highest mortality of all gynecological cancers, and its progression is often without symptoms. Clinical outcome and survival may be improved if the disease is identified in the early stages. The objective of the study was to evaluate the utility of the serum biomarkers human epididymi...

journal_title：Oncology letters

authors： Fritz-Rdzanek A,Grzybowski W,Beta J,Durczyński A,Jakimiuk A

更新日期：2012-09-01 00:00:00

abstract：:The aim of the present study was to investigate the expression of activin A in esophageal carcinoma and its association with tumor differentiation and metastasis. A total of 57 esophageal carcinoma patients and 36 controls were included in the current study. The mRNA and protein expression levels of activin A in esoph...

journal_title：Oncology letters

authors： Wang Z,Zhang N,Song R,Fan R,Yang L,Wu L

更新日期：2015-07-01 00:00:00

abstract：:Metastasis remains a notable issue in patients with newly diagnosed colorectal carcinomas (CRC). Although anti-angiogenic therapies target metastatic diseases, hypoxia-inducible factor-1 α (HIF-1α) and vascular endothelial growth factor (VEGF) status are routinely evaluated in primary tumors as metastatic sites are in...

journal_title：Oncology letters

authors： Yin L,Li J,Ma D,Li D,Sun Y

更新日期：2020-05-01 00:00:00

abstract：:Synovial sarcoma (SS) is a soft tissue sarcoma of unknown histogenesis that rarely occurs in the female genital tract. We report a case of SS occurring in the right vulva of a young Japanese female. The tumor was composed of poorly differentiated rounded cell areas, surrounded by fibroblastic spindle-shaped cell areas...

journal_title：Oncology letters

authors： Kawauchi S,Ihara K,Nishikawa K,Sugino N,Takahashi M,Sasaki1 K

更新日期：2012-11-01 00:00:00

abstract：:Human umbilical cord-derived mesenchymal stem cells (hUCMSCs) represent potential therapeutic tools for solid tumors. However, there are numerous inconsistent results regarding the effects of hUCMSCs on tumors, and the mechanisms underlying this remain poorly understood. The present study further examined this controv...

journal_title：Oncology letters

authors： Yuan Y,Zhou C,Chen X,Tao C,Cheng H,Lu X

更新日期：2018-06-01 00:00:00

abstract：:The soluble urokinase-type plasminogen activator receptor (suPAR) and the urokinase-type plasminogen activator receptor (uPAR) have been proposed as useful biomarkers of tumor progression. Recently, suPAR was associated with chemoresistance in lung cancer. However, its clinical significance in leukemia has not previou...

journal_title：Oncology letters

authors： Guo H,Zhou LX,Ma H,Liu B,Cheng J,Ma YY,Zhao L

更新日期：2017-07-01 00:00:00

abstract：:Autophagy is a lysosomal degradation process which is key for the regulation of the turnover of long-lived or damaged proteins and organelles and which promotes cell survival during nutrient deprivation or other microenvironmental stresses. Current evidence supports the hypothesis that autophagy suppresses tumorigenes...

journal_title：Oncology letters

authors： Xu Y,Xia X,Pan H

更新日期：2013-02-01 00:00:00