Anillin is a prognostic factor and is correlated with genovariation in pancreatic cancer based on databases analysis.

abstract：:The aim of the present study was to establish a prediction index (PI) model for the 5-year survival rate of patients with hepatitis B-related hepatocellular carcinoma (HCC) after radical resection, and to evaluate the effect of prophylactic transcatheter arterial chemoembolization (TACE). A total of 201 patients with ...

journal_title：Oncology letters

authors： He S,Fan X,Ma H,Xiaerfuhazi H,Rehato A,Feng J,Shi X,He F

更新日期：2019-08-01 00:00:00

abstract：:Natural products are a promising source for the development of novel cancer therapies, due to their potential effectiveness and low toxicity profiles. As a main component of Herba oxytropis, 2',4'-dihydroxychalcone (TFC) is known to demonstrate anti-tumor activity in vitro. In the present study, TFC was found to potent...

journal_title：Oncology letters

authors： Sheng Y,Zou M,Wang Y,Li Q

更新日期：2015-12-01 00:00:00

abstract：:A 77-year-old female, with proptosis, reduced eye motility and diplopia which had developed over two to three months and a 69-year-old female with proptosis, oedema of the eyelid, reduced motility and ptosis, which had developed over three weeks, are presented in the present study. Computed tomography scans revealed i...

journal_title：Oncology letters

authors： Nickelsen MN,VON Holstein S,Hansen AB,Prause JU,Heegaard S

更新日期：2015-08-01 00:00:00

abstract：:Transforming growth factor β (TGFβ) ligands, including TGFβ1, are multifunctional cytokines known as key regulators of cell growth, differentiation and inflammation. Dysregulated TGFβ signaling is common in numerous solid tumors, including head and neck squamous cell carcinoma (HNSCC). Previously, TGFβ ligands were al...

journal_title：Oncology letters

authors： Bae WJ,Lee SH,Rho YS,Koo BS,Lim YC

更新日期：2016-12-01 00:00:00

abstract：:The frequency of deficient mismatch repair (dMMR) or microsatellite instability-high colorectal cancer (CRC) is estimated to be ~15% of all patients with CRC; however, the patients reported are limited to surgical cases, and the frequency of patients exhibiting stage 0 disease is not considered, despite the currently ...

journal_title：Oncology letters

authors： Sugiyama T,Iwaizumi M,Kaneko M,Tani S,Yamade M,Hamaya Y,Furuta T,Miyajima H,Osawa S,Baba S,Maekawa M,Sugimoto K

更新日期：2020-09-01 00:00:00

abstract：:The seven-amino acid truncated (7ND) protein is an N-terminal deletion mutant of monocyte chemoattractant protein-1 (MCP-1) and it functions as a dominant-negative inhibitor. 7ND and wild-type MCP-1 form a heterodimer, which binds to MCP-1 receptors and inhibits monocyte chemotaxis. In the present study, the 7ND prote...

journal_title：Oncology letters

authors： Luo S,Zhou C,Zhang J,Chen M,Li H,Zheng S,Quan J

更新日期：2018-05-01 00:00:00

abstract：:Thyroid carcinoma is the most prevalent endocrine neoplasm globally. In the majority of thyroid carcinoma cases, a positive prognosis is predicted following administration of the appropriate treatment. A wide range of genetic alterations present in thyroid carcinoma exert their oncogenic actions partially through the ...

journal_title：Oncology letters

authors： Jiang L,Chu H,Zheng H

更新日期：2016-04-01 00:00:00

abstract：:Gastric cancer (GC) is one of the most common malignancies and is the second leading cause of cancer-associated mortality world-wide. In the present study, the prognostic value and antitumor effects of transforming growth factor β1 (TGFβ1) and its receptors in GC were explored. The online Kaplan-Meier plotter database...

journal_title：Oncology letters

authors： Liu F,Wang H,Zhang M

更新日期：2020-09-01 00:00:00

abstract：:Point mutation of the BRAF gene is a genetic event that occurs in a subset of lung adenocarcinoma cases. For example, BRAF V600E is a driver mutation that can be effectively targeted using selective BRAF and/or MEK inhibitors. The present study hypothesized that an increase in BRAF copy number may be correlated with c...

journal_title：Oncology letters

authors： Sasaki H,Maekawa M,Tatematsu T,Okuda K,Moriyama S,Yano M,Fujii Y

更新日期：2015-02-01 00:00:00

abstract：:The recent successful use of the immune checkpoint inhibitors (CPIs) anti-programmed death receptor-1 (PD-1)/PD-1 ligand 1 in clinical trials indicates their crucial role in obtaining an effective cancer immune therapy. These CPIs have been identified to have an effective therapeutic response, particularly in tumors w...

journal_title：Oncology letters

authors： Cai LL,Wang J

更新日期：2019-06-01 00:00:00

abstract：:The aim of this study was to evaluate the efficacy of multi-detector row helical computed tomography (MDCT) angiography in the detection of feeding arteries prior to multi-arterial infusion for lung cancer. A total of 59 consecutive patients (44 males and 15 females; age range, 27-86 years; median age, 62 years) with ...

journal_title：Oncology letters

authors： Ye XD,Yuan Z,Ye JD,Xiao XS

更新日期：2013-01-01 00:00:00

abstract：:The CDw75 epitope is an α(2,6) sialylated antigen overexpressed in colorectal cancer (CRC), where its expression correlates with the progression of the disease. The CDw75 epitope is located mainly in N-glycoproteins, whose identity remains unknown. The aim of the present study was to identify proteins with the CDw75 e...

journal_title：Oncology letters

authors： Mariño-Crespo Ó,Fernández-Briera A,Gil-Martín E

更新日期：2018-01-01 00:00:00

abstract：:Non-small cell lung cancer (NSCLC) is the most common cause of cancer-associated mortality worldwide. Prostaglandin E2 (PGE2) regulates various biological processes, including invasion, proliferation and apoptosis. E-prostanoid 3 (Ep3) is a PGE2 receptor, and the functional role of Ep3 in the progression of NSCLC rema...

journal_title：Oncology letters

authors： Li L,Lv Y,Yan D

更新日期：2018-11-01 00:00:00

abstract：:A gallbladder neuroendocrine neoplasm (GB-NEN) is a unique heterogeneous neoplasm, originating from neuroendocrine cells and able to secrete peptides as its neurotransmitter. Among all the neuroendocrine tumors (NETs), the GB-NEN prevalence is 0.5%, which accounts for ~2.1% of all gallbladder tumors. The current study...

journal_title：Oncology letters

authors： Niu C,Wang S,Guan Q,Ren X,Ji B,Liu Y

更新日期：2020-05-01 00:00:00

abstract：:Dendrobium candidum Wall ex Lindl. (D. candidum) is a traditional Chinese medicine widely used in Asia. The present study has showed that D. candidum exerted an anti-metastatic effect in mice injected with 26-M3.1 colon carcinoma cells. D. candidum showed the most marked tumor inhibitory rate of 64.5% at a dose of 400...

journal_title：Oncology letters

authors： Li G,Sun P,Zhou Y,Zhao X,Chen F

更新日期：2014-10-01 00:00:00

abstract：:Diagnostic assays for human epidermal growth factor receptor 2 (HER2) expression have a high predictive value because patients with HER2-positive tumors could benefit from HER2-targeted therapy. The aim of the present study is to analyze the incidence of HER2 gene amplification in selected tumors with adverse features...

journal_title：Oncology letters

authors： Petroni S,Caldarola L,Scamarcio R,Giotta F,Latorre A,Mangia A,Simone G

更新日期：2016-11-01 00:00:00

abstract：:Breast cancer is a highly heterogeneous disease at the molecular level and >90% of mortalities are due to metastasis and its associated complications. The present study determined the impact of molecular subtypes on metastatic behavior and overall survival (OS) of patients with metastatic breast cancer. The influence ...

journal_title：Oncology letters

authors： Yang H,Wang R,Zeng F,Zhao J,Peng S,Ma Y,Chen S,Ding S,Zhong L,Guo W,Wang W

更新日期：2020-10-01 00:00:00

abstract：:The aim of the present study was to investigate the effects of the mammalian target of rapamycin (mTOR) inhibitor, RAD001, on the growth of human endometrial cancer cells. The effects of RAD001 on human endometrial cancer Ishikawa and HEC-1A cell proliferation were determined by MTT assay. Green fluorescent protein mi...

journal_title：Oncology letters

authors： Wang H,Li D,Li X,Ou X,Liu S,Zhang Y,Ding J,Xie B

更新日期：2016-12-01 00:00:00

abstract：:Being biomarkers that reflect host nutritional and immune status, prognostic nutritional index (PNI) and neutrophil/lymphocyte ratio (NLR) have been identified to be independent prognostic factors in various malignancies. The aim of the present study was to determine the predictive value of these parameters for the pr...

journal_title：Oncology letters

authors： Yang T,Mao P,Chen X,Niu X,Xu G,Bai X,Xie W

更新日期：2019-02-01 00:00:00

abstract：:Polymorphisms of the vitamin D receptor (VDR) gene may be a risk factor for pancreatic cancer (PC). We investigated the association of two single-nucleotide polymorphisms (SNPs) of the VDR gene with PC in age- and gender-matched patients and controls. PC (n=91) and healthy control (n=80) samples were genotyped for the...

journal_title：Oncology letters

authors： Li L,Wu B,Yang L,Yin G,Wei W,Sui S,Liu J

更新日期：2013-05-01 00:00:00

abstract：:The current report presents the case of a 43-year-old male suffering from a penile cutaneous horn. A surgical excision of the lesion was performed and histopathology demonstrated hyperkeratosis, dyskeratosis and epithelial hyperplasia. The cutaneous horn progressed to squamous cell carcinoma <1.5 months following surg...

journal_title：Oncology letters

authors： Zhou Y,Tang Y,Tang J,Xia B,Dai Y

更新日期：2014-09-01 00:00:00

abstract：:Gefitinib is a selective inhibitor of the tyrosine kinase epidermal growth factor receptor, which inhibits tumor pathogenesis, metastasis and angiogenesis, as well as promoting apoptosis. Therefore, gefitinib presents an effective drug for the targeted therapy of lung cancer. However, the underlying mechanisms by whic...

journal_title：Oncology letters

authors： Zhao ZQ,Yu ZY,Li J,Ouyang XN

更新日期：2016-07-01 00:00:00

abstract：:Integrin signaling may modulate several different functions involved in cell migration, invasion, proliferation and motility, and is a potential candidate biomarker for oral cancer. In the present study, a total of four integrin genes were evaluated as potential biomarkers of oral squamous cell carcinoma (OSCC). Gene ...

journal_title：Oncology letters

authors： Chang HW,Yen CY,Chen CH,Tsai JH,Tang JY,Chang YT,Kao YH,Wang YY,Yuan SF,Lee SY

更新日期：2018-10-01 00:00:00

abstract：:Changes in the expression of regulator of G protein signaling 2 (RGS2) are involved in the genesis and development of a number of malignancies. However, the association between changes in the expression of RGS2 and breast invasive carcinoma of no special type (BIC-NST) remains unknown. The present study found that, in...

journal_title：Oncology letters

authors： Wang C,Ye Q,Cao Y,Tan J,Wang F,Jiang J,Cao Y

更新日期：2018-01-01 00:00:00

abstract：:The inhibitory effect of resveratrol on the growth of gastric cancer cells through downregulation of the Wnt/β-catenin signaling pathway were studied. First we determined the effective concentration of resveratrol on the growth and proliferation of MGC-803 gastric cancer cells. Methylthiazolyl tetrazolium assay showed...

journal_title：Oncology letters

authors： Dai H,Deng HB,Wang YH,Guo JJ

更新日期：2018-08-01 00:00:00

abstract：:The aim of the present study was to develop a water-soluble biomarker for the detection of breast cancer using quantum dots (QDs) conjugated to Ki-67, a nuclear protein associated with the cell cycle. Ki-67 is also a marker of cell proliferation, with expression levels categorizing good and poor prognosis in invasive ...

journal_title：Oncology letters

authors： Sun G,Xing W,Xing R,Cong L,Tong S,Yu S

更新日期：2018-02-01 00:00:00

abstract：:Tuberous sclerosis complex (TSC) is an autosomal dominant disease involving multiple organs, but there are a limited number of reports on family TSC. In the present report, a case of a 52-year-old female with a familial genetic TSC, associated with bilateral giant renal angiomyolipoma, was described. The mother, secon...

journal_title：Oncology letters

authors： Wang L,Ni D,Zhong L,Wang J

更新日期：2017-12-01 00:00:00

abstract：:The present study aimed to identify the regulatory mechanisms associated with the metastasis of prostate cancer (PC). The microRNA (miRNA/miR) microarray dataset GSE21036 and gene transcript dataset GSE21034 were downloaded from the Gene Expression Omnibus database. Following pre-processing, differentially expressed m...

journal_title：Oncology letters

authors： Guo K,Liang Z,Li F,Wang H

更新日期：2017-11-01 00:00:00

abstract：:Clear cell myoepithelial carcinoma is a very rare disease which develops primarily in the parotid gland. To date, only 17 cases of clear cell myoepithelial carcinoma have been reported worldwide. Among them, only three cases developed in the minor salivary gland in the oral cavity. No cases developed in the base of th...

journal_title：Oncology letters

authors： Park JH,Choi JY,Hong R,DO NY

更新日期：2012-12-01 00:00:00

abstract：:The present study was conducted to evaluate the methanolic extract of Piper betle leaves (MPBL) and its organic fractions with regard to antitumor activity against Ehrlich ascites carcinoma (EAC) in Swiss albino mice and to confirm their antioxidant activities. At 24 h post-intraperitoneal inoculation of tumor cells i...

journal_title：Oncology letters

authors： Alam B,Majumder R,Akter S,Lee SH

更新日期：2015-02-01 00:00:00